PE20090941A1 - Asociacion entre un antiaterotrombotico y un inhibidor de la enzima de conversion de la angiotensina - Google Patents
Asociacion entre un antiaterotrombotico y un inhibidor de la enzima de conversion de la angiotensinaInfo
- Publication number
- PE20090941A1 PE20090941A1 PE2008001404A PE2008001404A PE20090941A1 PE 20090941 A1 PE20090941 A1 PE 20090941A1 PE 2008001404 A PE2008001404 A PE 2008001404A PE 2008001404 A PE2008001404 A PE 2008001404A PE 20090941 A1 PE20090941 A1 PE 20090941A1
- Authority
- PE
- Peru
- Prior art keywords
- compound
- inhibitor
- conversion enzyme
- antiaterotrombotic
- association
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/15—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/18—Sulfonamides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/01—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms
- C07C311/02—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
- C07C311/03—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton having the nitrogen atoms of the sulfonamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C311/06—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton having the nitrogen atoms of the sulfonamide groups bound to hydrogen atoms or to acyclic carbon atoms to acyclic carbon atoms of hydrocarbon radicals substituted by carboxyl groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/15—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings
- C07C311/20—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to a carbon atom of a ring other than a six-membered aromatic ring
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Epidemiology (AREA)
- Obesity (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Rheumatology (AREA)
- Child & Adolescent Psychology (AREA)
- Vascular Medicine (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Emergency Medicine (AREA)
- Ophthalmology & Optometry (AREA)
- Hospice & Palliative Care (AREA)
- Endocrinology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
Abstract
REFERIDA A UNA COMBINACION DEL COMPUESTO TERUTROBAN (ACIDO 3-[(6R)-6-[[4-CLOROFENIL)SULFONIL]AMINO]-2-METIL-5,6,7,8-TETRAHIDRONAFTALEN-1-IL]-PROPANOICO -COMPUESTO (A)) Y UN INHIBIDOR DE LA ENZIMA DE CONVERSION DE LA ANGIOTENSINA TAL COMO PERINDOPRIL, DONDE EL COMPUESTO A, OPCIONALMENTE, SE ENCUENTRA BAJO LA FORMA DE ISOMERO OPTICO O DE UNA DE SUS SALES FARMACEUTICAMENTE ACEPTABLES Y EL PESO TOTAL DE LOS PRINCIPIOS ACTIVOS ESTA DISTRIBUIDO ENTRE 60% Y 90% PARA EL COMPUESTO A Y ENTRE 10% Y 40% PARA EL PERINDOPRIL. DICHA COMBINACION ES UTIL EN EL TRATAMIENTO DE COMPLICACIONES VASCULARES ASOCIADAS A DIABETES, ENFERMEDADES ATEROTROMBOTICAS, HIPERLIPIDEMIA, HIPERTENSION, ENTRE OTRAS
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0706345A FR2920772B1 (fr) | 2007-09-11 | 2007-09-11 | Association entre un anti-atherothrombotique et un inhibiteur de l'enzyme de conversion de l'angiotensine |
Publications (1)
Publication Number | Publication Date |
---|---|
PE20090941A1 true PE20090941A1 (es) | 2009-07-18 |
Family
ID=39366989
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PE2008001404A PE20090941A1 (es) | 2007-09-11 | 2008-08-19 | Asociacion entre un antiaterotrombotico y un inhibidor de la enzima de conversion de la angiotensina |
Country Status (27)
Country | Link |
---|---|
US (1) | US20090075976A1 (es) |
EP (1) | EP2036886A1 (es) |
JP (1) | JP2009067793A (es) |
KR (1) | KR20090027167A (es) |
CN (1) | CN101385723A (es) |
AP (1) | AP2008004590A0 (es) |
AR (1) | AR068385A1 (es) |
AU (1) | AU2008207584A1 (es) |
BR (1) | BRPI0804140A2 (es) |
CA (1) | CA2638354A1 (es) |
CL (1) | CL2008002653A1 (es) |
CO (1) | CO6020018A1 (es) |
CR (1) | CR10228A (es) |
EA (1) | EA200801829A1 (es) |
EC (1) | ECSP088713A (es) |
FR (1) | FR2920772B1 (es) |
GT (2) | GT200800169A (es) |
IL (1) | IL193585A0 (es) |
MA (1) | MA30374B1 (es) |
MX (1) | MX2008011329A (es) |
NZ (1) | NZ571144A (es) |
PA (1) | PA8795401A1 (es) |
PE (1) | PE20090941A1 (es) |
SG (1) | SG151171A1 (es) |
TW (1) | TW200920354A (es) |
UY (1) | UY31304A1 (es) |
WO (1) | WO2009066035A2 (es) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20130190370A1 (en) * | 2010-07-29 | 2013-07-25 | The Trustees Of The University Of Pennsylvania | Novel Tetrahydronaphalene Antagonists to the Thromboxane A2 (TP) Receptor |
CN109248319A (zh) * | 2017-07-14 | 2019-01-22 | 郜建敏 | 含有司坦类化合物和阿司匹林的药物组合物 |
WO2020060823A1 (en) * | 2018-09-18 | 2020-03-26 | Eli Lilly And Company | Erbumine salt of treprostinil |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2711139B1 (fr) * | 1993-10-15 | 1995-12-01 | Adir | Nouveaux dérivés de 1,2,3,4-tétrahydronaphtalène, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent. |
US6509348B1 (en) * | 1998-11-03 | 2003-01-21 | Bristol-Myers Squibb Company | Combination of an ADP-receptor blocking antiplatelet drug and a thromboxane A2 receptor antagonist and a method for inhibiting thrombus formation employing such combination |
FR2838057B1 (fr) * | 2002-04-05 | 2005-07-08 | Servier Lab | Nouvelle association d'un antithrombotique et d'aspirine |
FR2857593B1 (fr) * | 2003-07-18 | 2005-10-14 | Servier Lab | Composition pharmaceutique orodispersible d'un compose antithrombotique |
FR2860436B1 (fr) * | 2003-10-03 | 2006-01-20 | Servier Lab | Nouvelle association d'un anti-atherothrombotique et d'un antiagregant plaquettaire |
FR2894825B1 (fr) * | 2005-12-21 | 2010-12-03 | Servier Lab | Nouvelle association d'un inhibiteur du courant if sinusal et d'un inhibiteur de l'enzyme de conversion et les compositions pharmaceutiques qui la contiennent |
-
2007
- 2007-09-11 FR FR0706345A patent/FR2920772B1/fr not_active Expired - Fee Related
-
2008
- 2008-08-19 PE PE2008001404A patent/PE20090941A1/es not_active Application Discontinuation
- 2008-08-20 CR CR10228A patent/CR10228A/es not_active Application Discontinuation
- 2008-08-20 SG SG200806159-0A patent/SG151171A1/en unknown
- 2008-08-21 UY UY31304A patent/UY31304A1/es unknown
- 2008-08-21 IL IL193585A patent/IL193585A0/en unknown
- 2008-08-26 AP AP2008004590A patent/AP2008004590A0/xx unknown
- 2008-08-28 AU AU2008207584A patent/AU2008207584A1/en not_active Abandoned
- 2008-09-02 TW TW097133649A patent/TW200920354A/zh unknown
- 2008-09-02 GT GT200800169A patent/GT200800169A/es unknown
- 2008-09-03 EC EC2008008713A patent/ECSP088713A/es unknown
- 2008-09-04 MX MX2008011329A patent/MX2008011329A/es not_active Application Discontinuation
- 2008-09-05 GT GT200800178A patent/GT200800178A/es unknown
- 2008-09-08 MA MA31217A patent/MA30374B1/fr unknown
- 2008-09-08 CL CL2008002653A patent/CL2008002653A1/es unknown
- 2008-09-08 US US12/231,981 patent/US20090075976A1/en not_active Abandoned
- 2008-09-09 PA PA20088795401A patent/PA8795401A1/es unknown
- 2008-09-09 JP JP2008230403A patent/JP2009067793A/ja active Pending
- 2008-09-09 AR ARP080103905A patent/AR068385A1/es not_active Application Discontinuation
- 2008-09-10 EP EP08290847A patent/EP2036886A1/fr not_active Withdrawn
- 2008-09-10 KR KR1020080089346A patent/KR20090027167A/ko not_active Application Discontinuation
- 2008-09-10 CA CA002638354A patent/CA2638354A1/fr not_active Abandoned
- 2008-09-10 WO PCT/FR2008/001261 patent/WO2009066035A2/fr active Application Filing
- 2008-09-10 BR BRPI0804140-7A patent/BRPI0804140A2/pt not_active IP Right Cessation
- 2008-09-10 NZ NZ571144A patent/NZ571144A/en not_active IP Right Cessation
- 2008-09-10 EA EA200801829A patent/EA200801829A1/ru unknown
- 2008-09-11 CO CO08095778A patent/CO6020018A1/es not_active Application Discontinuation
- 2008-09-11 CN CNA2008102135510A patent/CN101385723A/zh active Pending
Also Published As
Publication number | Publication date |
---|---|
GT200800178A (es) | 2010-07-02 |
BRPI0804140A2 (pt) | 2009-06-16 |
PA8795401A1 (es) | 2009-04-23 |
CR10228A (es) | 2009-04-28 |
US20090075976A1 (en) | 2009-03-19 |
UY31304A1 (es) | 2008-09-30 |
MA30374B1 (fr) | 2009-05-04 |
AP2008004590A0 (en) | 2008-08-31 |
EP2036886A1 (fr) | 2009-03-18 |
GT200800169A (es) | 2010-05-21 |
CA2638354A1 (fr) | 2009-03-11 |
FR2920772B1 (fr) | 2009-10-23 |
FR2920772A1 (fr) | 2009-03-13 |
WO2009066035A3 (fr) | 2009-08-27 |
CL2008002653A1 (es) | 2009-06-05 |
AU2008207584A1 (en) | 2009-03-26 |
SG151171A1 (en) | 2009-04-30 |
WO2009066035A2 (fr) | 2009-05-28 |
KR20090027167A (ko) | 2009-03-16 |
AR068385A1 (es) | 2009-11-11 |
CO6020018A1 (es) | 2009-03-31 |
NZ571144A (en) | 2010-01-29 |
IL193585A0 (en) | 2011-08-01 |
CN101385723A (zh) | 2009-03-18 |
JP2009067793A (ja) | 2009-04-02 |
ECSP088713A (es) | 2008-10-31 |
MX2008011329A (es) | 2009-03-10 |
TW200920354A (en) | 2009-05-16 |
EA200801829A1 (ru) | 2009-06-30 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FA | Abandonment or withdrawal |