PE20081841A1 - Composiciones farmaceuticas con capacidad de induccion de apotosis en celulas tumorales, utiles para el diagnostico y tratamiento de la leucemia linfocitica cronica b - Google Patents
Composiciones farmaceuticas con capacidad de induccion de apotosis en celulas tumorales, utiles para el diagnostico y tratamiento de la leucemia linfocitica cronica bInfo
- Publication number
- PE20081841A1 PE20081841A1 PE2008000031A PE2008000031A PE20081841A1 PE 20081841 A1 PE20081841 A1 PE 20081841A1 PE 2008000031 A PE2008000031 A PE 2008000031A PE 2008000031 A PE2008000031 A PE 2008000031A PE 20081841 A1 PE20081841 A1 PE 20081841A1
- Authority
- PE
- Peru
- Prior art keywords
- diagnosis
- useful
- treatment
- tumor cells
- capacity
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2896—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against molecules with a "CD"-designation, not provided for elsewhere
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57407—Specifically defined cancers
- G01N33/57426—Specifically defined cancers leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Hematology (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Biochemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Microbiology (AREA)
- Oncology (AREA)
- Biotechnology (AREA)
- Pathology (AREA)
- Cell Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Food Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Physics & Mathematics (AREA)
- Hospice & Palliative Care (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
SE REFIERE A UNA COMPOSICION FARMACEUTICA QUE COMPRENDE UN ANTICUERPO MONOCLONAL HUMANIZADO QUE RECONOCE EL ANTIGENO DE DIFERENCIACION LEUCOCITARIO HUMANO CD6 (ANTI-CD6) T1h OBTENIDO A PARTIR DEL HIBRIDOMA SECRETOR IOR-T1A CON Nº DE DEPOSITO ECACC 96112640; QUE ADEMAS PUEDE ESTAR EN COMBINACION CON UN AGENTE QUIMIOTERAPEUTICO SELECCIONADO DE FOSFATO DE FLUDARABINA O ANTICUERPOS MONOCLONALES ESPECIFICOS CONTRA MOLECULAS DE SUPERFICIEDE LOS LINFOCITOS TUMORALES TAL COMO ANTI CD-20 Y UN EXCIPIENTE APROPIADO. ESTE ANTICUERPO INDUCE APOPTOSIS DE LAS CELULAS TUMORALES; SIENDO UTIL EN EL DIAGNOSTICO Y TRATAMIENTO DE SINDROMES LINFOPROLIFERATIVOS TAL COMO LEUCEMIA LINFOCITA CRONICA B
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CU20060249 | 2006-12-26 |
Publications (1)
Publication Number | Publication Date |
---|---|
PE20081841A1 true PE20081841A1 (es) | 2009-01-22 |
Family
ID=40261613
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PE2008000031A PE20081841A1 (es) | 2006-12-26 | 2008-01-02 | Composiciones farmaceuticas con capacidad de induccion de apotosis en celulas tumorales, utiles para el diagnostico y tratamiento de la leucemia linfocitica cronica b |
Country Status (19)
Country | Link |
---|---|
US (1) | US8435521B2 (es) |
EP (1) | EP2119453B1 (es) |
KR (1) | KR101482959B1 (es) |
CN (1) | CN101678101B (es) |
AU (1) | AU2007336564B2 (es) |
CA (1) | CA2676188C (es) |
CL (1) | CL2007003825A1 (es) |
DK (1) | DK2119453T3 (es) |
ES (1) | ES2542861T3 (es) |
HK (1) | HK1140696A1 (es) |
IT (1) | ITTO20070944A1 (es) |
JO (1) | JO3016B1 (es) |
MY (1) | MY154819A (es) |
NZ (1) | NZ578633A (es) |
PE (1) | PE20081841A1 (es) |
PL (1) | PL2119453T3 (es) |
PT (1) | PT2119453E (es) |
RU (1) | RU2454245C2 (es) |
WO (1) | WO2008077356A1 (es) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8524233B2 (en) | 2008-03-14 | 2013-09-03 | Biocon Limited & Centro de Immunologia Molecular | Monoclonal antibody and a method thereof |
AU2010320515B2 (en) * | 2009-11-20 | 2013-05-02 | Biocon Limited | Formulations of antibody |
NZ746944A (en) | 2013-07-23 | 2021-07-30 | Biocon Ltd | Use of a cd6 binding partner and method based thereon |
RU2619259C1 (ru) * | 2016-01-19 | 2017-05-12 | Сергей Анатольевич Фирсов | Способ экспресс-диагностики хронического алкоголизма при тяжелых сочетанных травмах |
WO2018073734A1 (en) | 2016-10-21 | 2018-04-26 | Biocon Limited | A monoclonal antibody and a method of use for the treatment of lupus |
BR112020017445A2 (pt) | 2018-02-27 | 2021-01-26 | Equillium, Inc. | anticorpos anti cd6 para tratar asma severa |
US20210395382A1 (en) * | 2018-10-05 | 2021-12-23 | The Regents Of The University Of Michigan | Compositions and methods for treating cancer |
JP2022521973A (ja) | 2019-02-26 | 2022-04-13 | エクイリウム,インコーポレイテッド | 抗cd6抗体組成物およびループスを処置するための方法 |
CN111257558B (zh) * | 2020-01-19 | 2021-08-24 | 江苏省人民医院(南京医科大学第一附属医院) | 基于机器学习的慢性淋巴细胞白血病肿瘤细胞识别方法 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5618920A (en) * | 1985-11-01 | 1997-04-08 | Xoma Corporation | Modular assembly of antibody genes, antibodies prepared thereby and use |
US5530101A (en) * | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
CU22615A1 (es) | 1994-06-30 | 2000-02-10 | Centro Inmunologia Molecular | Procedimiento de obtención de anticuerpos monoclonales murinos menos inmunogénicos. anticuerpos monoclonales obtenidos |
CU22584A1 (es) * | 1995-11-17 | 1999-11-03 | Centro Inmunologia Molecular | Composiciones farmacéuticas que contienen un anticuerpo monoclonal que reconoce el antígeno de diferenciación leucocitario humano cd6 y sus usos para el diagnóstico y tratamiento de la psoriasis |
WO1998043089A1 (en) * | 1997-03-03 | 1998-10-01 | Bristol-Myers Squibb Company | Monoclonal antibodies to human cd6 |
DE102005014071A1 (de) | 2005-03-23 | 2006-09-28 | Bühler AG | Herstellung eines Polyesters mit verbesserten Aufschmelzeigenschaften und Kristallisationseigenschaften |
US8524233B2 (en) * | 2008-03-14 | 2013-09-03 | Biocon Limited & Centro de Immunologia Molecular | Monoclonal antibody and a method thereof |
-
2007
- 2007-12-24 PL PL07855984T patent/PL2119453T3/pl unknown
- 2007-12-24 AU AU2007336564A patent/AU2007336564B2/en active Active
- 2007-12-24 WO PCT/CU2007/000022 patent/WO2008077356A1/es active Application Filing
- 2007-12-24 CA CA2676188A patent/CA2676188C/en active Active
- 2007-12-24 NZ NZ578633A patent/NZ578633A/en unknown
- 2007-12-24 PT PT78559846T patent/PT2119453E/pt unknown
- 2007-12-24 RU RU2009128660/15A patent/RU2454245C2/ru not_active IP Right Cessation
- 2007-12-24 MY MYPI20092716A patent/MY154819A/en unknown
- 2007-12-24 US US12/525,449 patent/US8435521B2/en active Active
- 2007-12-24 KR KR1020097015727A patent/KR101482959B1/ko active IP Right Grant
- 2007-12-24 EP EP07855984.6A patent/EP2119453B1/en active Active
- 2007-12-24 DK DK07855984.6T patent/DK2119453T3/en active
- 2007-12-24 CN CN2007800502487A patent/CN101678101B/zh not_active Expired - Fee Related
- 2007-12-24 ES ES07855984.6T patent/ES2542861T3/es active Active
- 2007-12-26 CL CL200703825A patent/CL2007003825A1/es unknown
- 2007-12-26 JO JOP/2007/0562A patent/JO3016B1/ar active
- 2007-12-27 IT IT000944A patent/ITTO20070944A1/it unknown
-
2008
- 2008-01-02 PE PE2008000031A patent/PE20081841A1/es not_active Application Discontinuation
-
2010
- 2010-07-29 HK HK10107259.9A patent/HK1140696A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
JO3016B1 (ar) | 2016-09-05 |
KR101482959B1 (ko) | 2015-01-15 |
US20100047242A1 (en) | 2010-02-25 |
HK1140696A1 (en) | 2010-10-22 |
EP2119453A4 (en) | 2010-11-24 |
EP2119453B1 (en) | 2015-05-20 |
PL2119453T3 (pl) | 2015-10-30 |
PT2119453E (pt) | 2015-09-01 |
EP2119453A1 (en) | 2009-11-18 |
CN101678101A (zh) | 2010-03-24 |
RU2454245C2 (ru) | 2012-06-27 |
CN101678101B (zh) | 2012-11-07 |
AU2007336564B2 (en) | 2012-11-01 |
ITTO20070944A1 (it) | 2008-06-27 |
KR20090122911A (ko) | 2009-12-01 |
CA2676188C (en) | 2013-02-05 |
CL2007003825A1 (es) | 2008-05-16 |
NZ578633A (en) | 2012-03-30 |
DK2119453T3 (en) | 2015-07-27 |
MY154819A (en) | 2015-07-31 |
US8435521B2 (en) | 2013-05-07 |
AU2007336564A1 (en) | 2008-07-03 |
ES2542861T3 (es) | 2015-08-12 |
CA2676188A1 (en) | 2008-07-03 |
RU2009128660A (ru) | 2011-02-10 |
WO2008077356A1 (es) | 2008-07-03 |
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Legal Events
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