PE20081138A1 - Metabolitos aislados de hidroxi y n-oxido y derivados de desmetil venlafaxina y metodos de tratamiento - Google Patents
Metabolitos aislados de hidroxi y n-oxido y derivados de desmetil venlafaxina y metodos de tratamientoInfo
- Publication number
- PE20081138A1 PE20081138A1 PE2007001445A PE2007001445A PE20081138A1 PE 20081138 A1 PE20081138 A1 PE 20081138A1 PE 2007001445 A PE2007001445 A PE 2007001445A PE 2007001445 A PE2007001445 A PE 2007001445A PE 20081138 A1 PE20081138 A1 PE 20081138A1
- Authority
- PE
- Peru
- Prior art keywords
- hydroxy
- oxide
- treatment
- desmetil
- venlafaxin
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
- C07C215/46—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
- C07C215/64—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with rings other than six-membered aromatic rings being part of the carbon skeleton
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/34—Tobacco-abuse
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C291/00—Compounds containing carbon and nitrogen and having functional groups not covered by groups C07C201/00 - C07C281/00
- C07C291/02—Compounds containing carbon and nitrogen and having functional groups not covered by groups C07C201/00 - C07C281/00 containing nitrogen-oxide bonds
- C07C291/04—Compounds containing carbon and nitrogen and having functional groups not covered by groups C07C201/00 - C07C281/00 containing nitrogen-oxide bonds containing amino-oxide bonds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Addiction (AREA)
- Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Saccharide Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Abstract
SE REFIERE A UN COMPUESTO DE FORMULA I, CARACTERIZADO POR QUE EL GRUPO HIDROXI SE UNE A UN CARBONO EN LA POSICION 2, 3 O 4 SOBRE EL ANILLO CICLOHEXILO. SON PREFERIDOS: 2-HIDROXI DV; 2-HIDROXI DV GLUCORONIDO; N-OXIDO DV; ENTRE OTROS. SE REFIERE TAMBIEN A UN PROCEDIMIENTO DE OBTENCION Y COMPOSICION FARMACEUTICA. DICHO COMPUESTO ES UN METABOLITO DE O-DESMETILVENLAFAXINA (DV) Y ES UTIL EN EL TRATAMIENTO DE TRASTORNOS DEL SISTEMA NERVIOSO CENTRAL
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US85406306P | 2006-10-25 | 2006-10-25 |
Publications (1)
Publication Number | Publication Date |
---|---|
PE20081138A1 true PE20081138A1 (es) | 2008-09-18 |
Family
ID=39103391
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PE2007001445A PE20081138A1 (es) | 2006-10-25 | 2007-10-24 | Metabolitos aislados de hidroxi y n-oxido y derivados de desmetil venlafaxina y metodos de tratamiento |
Country Status (12)
Country | Link |
---|---|
US (1) | US20080261895A1 (es) |
EP (1) | EP2086922A2 (es) |
JP (1) | JP2010507667A (es) |
CN (1) | CN101528667A (es) |
AR (1) | AR063376A1 (es) |
CA (1) | CA2666350A1 (es) |
CL (1) | CL2007003067A1 (es) |
MX (1) | MX2009004247A (es) |
PE (1) | PE20081138A1 (es) |
RU (1) | RU2009112105A (es) |
TW (1) | TW200826925A (es) |
WO (1) | WO2008051558A2 (es) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7696383B2 (en) * | 2007-06-26 | 2010-04-13 | Solvay Pharmaceuticals B.V. | N-oxides of venlafaxine and o-desmethylvenlafaxine as prodrugs |
CN109761826B (zh) * | 2019-01-17 | 2022-02-25 | 烟台大学 | 一种o-去甲基文拉法辛苯醚化合物及其制备方法和用途 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4535186A (en) * | 1983-04-19 | 1985-08-13 | American Home Products Corporation | 2-Phenyl-2-(1-hydroxycycloalkyl or 1-hydroxycycloalk-2-enyl)ethylamine derivatives |
EP1153603B1 (en) * | 1993-06-28 | 2006-10-18 | Wyeth | New treatments using phenethylamine derivatives |
HUP0303128A3 (en) * | 2001-02-12 | 2008-03-28 | Wyeth Corp | Novel succinate salt of o-desmethyl-venlafaxine, process for preparation thereof, its use and pharmaceutical composition containing it |
-
2007
- 2007-10-24 PE PE2007001445A patent/PE20081138A1/es not_active Application Discontinuation
- 2007-10-24 WO PCT/US2007/022525 patent/WO2008051558A2/en active Application Filing
- 2007-10-24 CA CA002666350A patent/CA2666350A1/en not_active Abandoned
- 2007-10-24 CN CNA2007800394478A patent/CN101528667A/zh active Pending
- 2007-10-24 MX MX2009004247A patent/MX2009004247A/es not_active Application Discontinuation
- 2007-10-24 US US11/976,413 patent/US20080261895A1/en not_active Abandoned
- 2007-10-24 RU RU2009112105/04A patent/RU2009112105A/ru not_active Application Discontinuation
- 2007-10-24 AR ARP070104708A patent/AR063376A1/es unknown
- 2007-10-24 CL CL200703067A patent/CL2007003067A1/es unknown
- 2007-10-24 EP EP07852918A patent/EP2086922A2/en not_active Withdrawn
- 2007-10-24 JP JP2009534631A patent/JP2010507667A/ja active Pending
- 2007-10-25 TW TW096140034A patent/TW200826925A/zh unknown
Also Published As
Publication number | Publication date |
---|---|
US20080261895A1 (en) | 2008-10-23 |
AR063376A1 (es) | 2009-01-28 |
JP2010507667A (ja) | 2010-03-11 |
WO2008051558A3 (en) | 2008-08-14 |
CL2007003067A1 (es) | 2008-04-11 |
EP2086922A2 (en) | 2009-08-12 |
CN101528667A (zh) | 2009-09-09 |
TW200826925A (en) | 2008-07-01 |
WO2008051558A2 (en) | 2008-05-02 |
RU2009112105A (ru) | 2010-11-27 |
MX2009004247A (es) | 2009-05-14 |
CA2666350A1 (en) | 2008-05-02 |
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Legal Events
Date | Code | Title | Description |
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FA | Abandonment or withdrawal |