PE20080234A1 - Combinacion antiepileptica que comprende derivados de benzoheteroarilsulfamidas - Google Patents
Combinacion antiepileptica que comprende derivados de benzoheteroarilsulfamidasInfo
- Publication number
- PE20080234A1 PE20080234A1 PE2007000616A PE2007000616A PE20080234A1 PE 20080234 A1 PE20080234 A1 PE 20080234A1 PE 2007000616 A PE2007000616 A PE 2007000616A PE 2007000616 A PE2007000616 A PE 2007000616A PE 20080234 A1 PE20080234 A1 PE 20080234A1
- Authority
- PE
- Peru
- Prior art keywords
- sulfamide
- methyl
- benzoheteroarylsulfamides
- antiepileptic
- derivatives
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
- A61K31/381—Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
Abstract
REFERIDA A UN DERIVADO DE BENZOHETEROARILSULFAMIDA DE FORMULA (I), DONDE R1 ES H, HALOGENO, OH, METOXI, NITRO, ENTRE OTROS; X-Y ES -S-CH-, -O-CH-, -O-C(CH3)-, ENTRE OTROS; A ES -CH2- O -CH(CH3)-; R2 ES H O METILO; R3 Y R4 SON H O ALQUILO C1-C4 O JUNTO CON EL ATOMO DE NITROGENO AL CUAL ESTAN UNIDOS FORMAN UN ANILLO DE 5 A 7 MIEMBROS OPCIONALMENTE SUSTITUIDO CON O, N O S. SON COMPUESTOS PREFERIDOS: N-(BENZO[b]TIEN-3-ILMETIL)-SULFAMIDA, N-[(5-CLOROBENZO[b]TIEN-3-IL)METIL]-SULFAMIDA, N-[(5-FLUOROBENZO[b]TIEN-3-IL)METIL]-SULFAMIDA, ENTRE OTROS. DICHOS COMPUESTOS SON UTILES EN EL TRATAMIENTO DE LA EPILEPSIA Y TRASTORNOS RELACIONADOS. TAMBIEN ESTA REFERIDA A UNA COMBINACION FARMACEUTICA QUE COMPRENDE LOS COMPUESTOS DE FORMULA (I) Y OTRO AGENTE ANTIEPILEPTICO TAL COMO CARBAMAZEPINA, CLOBAZAM, CLONAZEPAM, GABAPENTINA, FENITOINA, ENTRE OTROS
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US80200106P | 2006-05-19 | 2006-05-19 |
Publications (1)
Publication Number | Publication Date |
---|---|
PE20080234A1 true PE20080234A1 (es) | 2008-04-25 |
Family
ID=38510389
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PE2007000616A PE20080234A1 (es) | 2006-05-19 | 2007-05-21 | Combinacion antiepileptica que comprende derivados de benzoheteroarilsulfamidas |
Country Status (7)
Country | Link |
---|---|
US (1) | US20070293476A1 (es) |
AR (1) | AR061066A1 (es) |
CL (1) | CL2007001468A1 (es) |
PE (1) | PE20080234A1 (es) |
TW (1) | TW200812574A (es) |
UY (1) | UY30360A1 (es) |
WO (1) | WO2007137164A2 (es) |
Families Citing this family (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TW200612905A (en) * | 2004-06-16 | 2006-05-01 | Janssen Pharmaceutica Nv | Novel sulfamate and sulfamide derivatives useful for the treatment of epilepsy and related disorders |
MY147767A (en) * | 2004-06-16 | 2013-01-31 | Janssen Pharmaceutica Nv | Novel sulfamate and sulfamide derivatives useful for the treatment of epilepsy and related disorders |
WO2006127184A1 (en) * | 2005-05-20 | 2006-11-30 | Janssen Pharmaceutica N.V. | Process for preparation of sulfamide derivatives |
US8937096B2 (en) * | 2005-12-19 | 2015-01-20 | Janssen Pharmaceutica Nv | Use of benzo-fused heterocyle sulfamide derivatives for the treatment of mania and bipolar disorder |
US20070155827A1 (en) * | 2005-12-19 | 2007-07-05 | Smith-Swintosky Virginia L | Use of benzo-fused heterocycle sulfamide derivatives for the treatment of depression |
US8497298B2 (en) * | 2005-12-19 | 2013-07-30 | Janssen Pharmaceutica Nv | Use of benzo-fused heterocycle sulfamide derivatives for lowering lipids and lowering blood glucose levels |
US8716231B2 (en) * | 2005-12-19 | 2014-05-06 | Janssen Pharmaceutica Nv | Use of benzo-fused heterocycle sulfamide derivatives for the treatment of pain |
US20070155823A1 (en) * | 2005-12-19 | 2007-07-05 | Smith-Swintosky Virginia L | Use of benzo-fused heterocycle sulfamide derivatives as neuroprotective agents |
US8691867B2 (en) * | 2005-12-19 | 2014-04-08 | Janssen Pharmaceutica Nv | Use of benzo-fused heterocycle sulfamide derivatives for the treatment of substance abuse and addiction |
AR058389A1 (es) * | 2005-12-19 | 2008-01-30 | Janssen Pharmaceutica Nv | Uso de derivados heterociclicos benzo-fusionados de sulfamida para el tratamiento de la obesidad |
US20070191474A1 (en) * | 2006-02-15 | 2007-08-16 | Smith-Swintosky Virginia L | Use of benzo-fused heterocyle sulfamide derivatives for the treatment of migraine |
AU2007253814A1 (en) * | 2006-05-19 | 2007-11-29 | Janssen Pharmaceutica N.V. | Co-therapy for the treatment of epilepsy |
EA019757B1 (ru) * | 2006-06-15 | 2014-06-30 | ЮСиБи ФАРМА ГМБХ | Фармацевтическая композиция с синергетическим противосудорожным эффектом |
US20090247617A1 (en) * | 2008-03-26 | 2009-10-01 | Abdel-Magid Ahmed F | Process for the preparation of benzo-fused heteroaryl sulfamates |
US20090247616A1 (en) * | 2008-03-26 | 2009-10-01 | Smith-Swintosky Virginia L | Use of benzo-fused heterocyle sulfamide derivatives for the treatment of anxiety |
AU2009271362B2 (en) | 2008-06-23 | 2014-03-13 | Janssen Pharmaceutica Nv | Crystalline form of (2s)-(-)-N-(6-chloro-2,3-dihydro-benzo[1,4]dioxin-2-ylmethyl)-sulfamide |
US8815939B2 (en) * | 2008-07-22 | 2014-08-26 | Janssen Pharmaceutica Nv | Substituted sulfamide derivatives |
US8609849B1 (en) | 2010-11-30 | 2013-12-17 | Fox Chase Chemical Diversity Center, Inc. | Hydroxylated sulfamides exhibiting neuroprotective action and their method of use |
US8652527B1 (en) | 2013-03-13 | 2014-02-18 | Upsher-Smith Laboratories, Inc | Extended-release topiramate capsules |
US9101545B2 (en) | 2013-03-15 | 2015-08-11 | Upsher-Smith Laboratories, Inc. | Extended-release topiramate capsules |
CA2961410C (en) | 2014-09-16 | 2023-07-11 | India Globalization Capital, Inc. | Cannabinoid composition and method for treating pain |
WO2016118391A1 (en) | 2015-01-25 | 2016-07-28 | India Globalization Capital, Inc. | Composition and method for treating seizure disorders |
WO2017027651A1 (en) | 2015-08-12 | 2017-02-16 | India Globalization Capital, Inc. | Method and composition for treating cachexia and eating disorders |
CA3027862A1 (en) | 2016-06-15 | 2017-12-21 | India Globalization Capital, Inc. | Method and composition for treating seizure disorders |
EP3769759B1 (en) | 2018-03-20 | 2023-11-15 | Eisai R&D Management Co., Ltd. | Combination of an indanesulfamide derivative with perampanel for use in the treatment of epilepsy |
WO2024054807A1 (en) * | 2022-09-06 | 2024-03-14 | Biohaven Therapeutics Ltd. | Combination therapies including metal channel activators and tdp-43 modulators |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4513006A (en) * | 1983-09-26 | 1985-04-23 | Mcneil Lab., Inc. | Anticonvulsant sulfamate derivatives |
WO1997019682A1 (en) * | 1995-12-01 | 1997-06-05 | Synaptic Pharmaceutical Corporation | Aryl sulfonamide and sulfamide derivatives and uses thereof |
CZ2002524A3 (cs) * | 1999-08-20 | 2002-11-13 | Ortho-Mcneil Pharmaceutical, Inc. | Kompozice obsahující tramadol a antikonvulziva |
CN1897950A (zh) * | 2003-10-14 | 2007-01-17 | 惠氏公司 | 稠合芳基和杂芳基衍生物及其使用方法 |
EP1727538A2 (en) * | 2004-02-13 | 2006-12-06 | Neuromolecular Inc. | Combination of an nmda receptor antagonist and an anti-epileptic drug for the treatment of epilepsy and other cns disorders |
AU2005277134A1 (en) * | 2004-08-24 | 2006-03-02 | Janssen Pharmaceutica N.V. | Novel benzo-fused heteroaryl sulfamide derivatives useful as anticonvulsant agents |
US20070191460A1 (en) * | 2006-02-15 | 2007-08-16 | Smith-Swintosky Virginia L | Use of Benzo-Heteroaryl Sulfamide Derivatives for the Treatment of Disease Modification / Epileptogenesis |
-
2007
- 2007-05-18 TW TW096117855A patent/TW200812574A/zh unknown
- 2007-05-18 WO PCT/US2007/069250 patent/WO2007137164A2/en active Application Filing
- 2007-05-18 US US11/750,579 patent/US20070293476A1/en not_active Abandoned
- 2007-05-21 AR ARP070102201A patent/AR061066A1/es not_active Application Discontinuation
- 2007-05-21 PE PE2007000616A patent/PE20080234A1/es not_active Application Discontinuation
- 2007-05-22 CL CL200701468A patent/CL2007001468A1/es unknown
- 2007-05-22 UY UY30360A patent/UY30360A1/es unknown
Also Published As
Publication number | Publication date |
---|---|
TW200812574A (en) | 2008-03-16 |
US20070293476A1 (en) | 2007-12-20 |
WO2007137164A2 (en) | 2007-11-29 |
UY30360A1 (es) | 2007-08-31 |
CL2007001468A1 (es) | 2008-04-04 |
AR061066A1 (es) | 2008-07-30 |
WO2007137164A3 (en) | 2008-01-17 |
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