NO20092230L - Azabicykliske heterocykler som cannabinoid reseptor modulatorer - Google Patents

Azabicykliske heterocykler som cannabinoid reseptor modulatorer

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Publication number
NO20092230L
NO20092230L NO20092230A NO20092230A NO20092230L NO 20092230 L NO20092230 L NO 20092230L NO 20092230 A NO20092230 A NO 20092230A NO 20092230 A NO20092230 A NO 20092230A NO 20092230 L NO20092230 L NO 20092230L
Authority
NO
Norway
Prior art keywords
formula
receptor modulators
cannabinoid receptor
therapeutic agents
additional therapeutic
Prior art date
Application number
NO20092230A
Other languages
English (en)
Inventor
Richard B Sulsky
William R Ewing
Yeheng Zhu
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Publication of NO20092230L publication Critical patent/NO20092230L/no

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
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    • A61P9/12—Antihypertensives

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
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  • Diabetes (AREA)
  • Immunology (AREA)
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  • Pulmonology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Addiction (AREA)
  • Pain & Pain Management (AREA)
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  • Dermatology (AREA)
  • Rheumatology (AREA)
  • Vascular Medicine (AREA)
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  • Transplantation (AREA)
  • Psychology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Anesthesiology (AREA)
  • Urology & Nephrology (AREA)
  • Reproductive Health (AREA)

Abstract

Foreliggende søknad beskriver forbindelser med formel I og Ia, farmasøytiske preparater som omfatter minst én forbindelse med formel I eller Ia og eventuelt ett eller flere ytterligere terapeutiske midler, og metoder for behandling ved anvendelse av forbindelsene i henhold til Formel I eller Ia, både alene og i kombinasjon med ett eller flere ytterligere terapeutiske midler. De foretrukne forbindelser har den generelle formel Ia nedenfor; som omfatter alle prodrugs, farmasøytisk akseptable salter og stereoisomerer derav, hvor R1, R2, Ar1, Ar2 er som definert her.
NO20092230A 2006-12-14 2009-06-10 Azabicykliske heterocykler som cannabinoid reseptor modulatorer NO20092230L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US86993306P 2006-12-14 2006-12-14
PCT/US2007/087404 WO2008076810A2 (en) 2006-12-14 2007-12-13 Azabicyclic heterocycles as cannabinoid receptor modulators

Publications (1)

Publication Number Publication Date
NO20092230L true NO20092230L (no) 2009-07-13

Family

ID=39343511

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20092230A NO20092230L (no) 2006-12-14 2009-06-10 Azabicykliske heterocykler som cannabinoid reseptor modulatorer

Country Status (8)

Country Link
US (1) US8030306B2 (no)
EP (1) EP2094705B1 (no)
JP (1) JP2010513307A (no)
CN (1) CN101631789A (no)
AT (1) ATE554092T1 (no)
ES (1) ES2384808T3 (no)
NO (1) NO20092230L (no)
WO (1) WO2008076810A2 (no)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UA111640C2 (uk) 2011-11-08 2016-05-25 Ф. Хоффманн-Ля Рош Аг ПОХІДНІ [1,2,3]ТРИАЗОЛО[4,5-d]ПІРИМІДИНУ ЯК АГОНІСТИ КАНАБІНОЇДНОГО РЕЦЕПТОРА 2
EP3215506B1 (en) 2014-11-07 2019-01-02 F.Hoffmann-La Roche Ag Triazolo[4,5-d]pyrimidines as agonists of the cannabinoid receptor 2

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL1697371T3 (pl) * 2003-12-19 2007-09-28 Bristol Myers Squibb Co Azabicykliczne heterocykle jako modulatory receptora kanabinoidowego
BRPI0515488A (pt) * 2004-09-20 2008-07-29 Xenon Pharmaceuticals Inc derivados de heterocìclicos e seu uso como agentes terapêuticos
US7629342B2 (en) 2005-06-17 2009-12-08 Bristol-Myers Squibb Company Azabicyclic heterocycles as cannabinoid receptor modulators
WO2009048544A1 (en) * 2007-10-10 2009-04-16 Merck & Co., Inc. Liquid pharmaceutical compositions for parenteral administration of a substituted amide

Also Published As

Publication number Publication date
US20100029656A1 (en) 2010-02-04
EP2094705A2 (en) 2009-09-02
EP2094705B1 (en) 2012-04-18
US8030306B2 (en) 2011-10-04
ATE554092T1 (de) 2012-05-15
WO2008076810A2 (en) 2008-06-26
JP2010513307A (ja) 2010-04-30
CN101631789A (zh) 2010-01-20
WO2008076810A3 (en) 2008-08-14
WO2008076810A9 (en) 2009-07-30
ES2384808T3 (es) 2012-07-12

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