PE20070098A1 - Formulacion de liberacion prolongada de principios activos que tienen solubilidad dependiente del ph - Google Patents
Formulacion de liberacion prolongada de principios activos que tienen solubilidad dependiente del phInfo
- Publication number
- PE20070098A1 PE20070098A1 PE2006000753A PE2006000753A PE20070098A1 PE 20070098 A1 PE20070098 A1 PE 20070098A1 PE 2006000753 A PE2006000753 A PE 2006000753A PE 2006000753 A PE2006000753 A PE 2006000753A PE 20070098 A1 PE20070098 A1 PE 20070098A1
- Authority
- PE
- Peru
- Prior art keywords
- derivatives
- excipient
- release formulation
- prolonged release
- active principles
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
- A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Anesthesiology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
REFERIDA A UNA FORMULACION DE LIBERACION PROLONGADA QUE COMPRENDE UN EXCIPIENTE MATRICIAL A BASE DE UN POLIMERO HIDROFILO, DONDE EL EXCIPIENTE MATRICIAL CONTIENE UNA DOSIS DETERMINADA DEL PRINCIPIO ACTIVO, CARACTERIZADA PORQUE COMPRENDE UNO O VARIOS AGENTES ACIDIFICANTES EN FORMA DE UNA SAL ACIDA DE UN ACIDO ORGANICO. LA SAL ACIDA DEL AGENTE ACIDIFICANTE SE SELECCIONA DE TARTRATO MONOPOTASICO, TERTRATO MONOSODICO, CITRATO MONOSODICO, CITRATO BISODICO Y/O MEZCLAS DE LAS MISMAS; EL PRINCIPIO ACTIVO SE SELECCIONA DE ZOLPIDEM, N-[2-[(4-AMINOCARBONIL)PIRIMIDIN-2-IL]AMINO]ETIL]-2-[[3-[4-(5-CLORO-2-METOXIFENIL)PIPERAZIN-1-IL]PROPIL]AMINOPIRIMIDIN-4-CARBOXIMIDA, CLORHIDRATO DE 5-(8-AMINO-7-CLORO-2,3-DIHIDRO-1,4-BENZODIOXIN-5-IL)-3-[1-(2-FENILETIL)PIPERIDIN-4-IL]-1,3,4-OXODIAZOL-2(3H)-ONA, 7-FLUORO.2-OXO-4-[2-[4-(TIENO-[3,2-c]-PIRIDIN-4-IL)PIPERAZIN-1-IL]ETIL]-1,2-DIHIDROQUINOLIN-1-ACETAMIDA, CLOPIDOGREL O MIZOLASTINA Y EL POLIMERO QUE FORMA EL EXCIPIENTE MATRICIAL SE SELECCIONA DE CELULOSA Y SUS DERIVADOS, GOMAS VEGETALES Y DERIVADOS DE ACIDO ALGINICO O ALMIDON Y SUS DERIVADOS. DICHA FORMULACION ES UTIL PARA PRINCIPIOS ACTIVOS QUE PRESENTAN UNA SOLUBILIDAD DEPENDIENTE DEL pH
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0506539A FR2887455B1 (fr) | 2005-06-28 | 2005-06-28 | Formulation a liberation prolongee de principes actifs de medicaments |
Publications (1)
Publication Number | Publication Date |
---|---|
PE20070098A1 true PE20070098A1 (es) | 2007-03-01 |
Family
ID=35708770
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PE2006000753A PE20070098A1 (es) | 2005-06-28 | 2006-06-28 | Formulacion de liberacion prolongada de principios activos que tienen solubilidad dependiente del ph |
Country Status (31)
Country | Link |
---|---|
US (1) | US20080089936A1 (es) |
EP (1) | EP1904037A1 (es) |
JP (1) | JP2008546830A (es) |
KR (1) | KR101387839B1 (es) |
CN (1) | CN101217943B (es) |
AR (1) | AR057410A1 (es) |
AU (1) | AU2006264856B2 (es) |
BR (1) | BRPI0612990A2 (es) |
CA (1) | CA2611125A1 (es) |
CR (1) | CR9567A (es) |
DO (1) | DOP2006000144A (es) |
EA (1) | EA013745B1 (es) |
EC (1) | ECSP078010A (es) |
FR (1) | FR2887455B1 (es) |
GT (1) | GT200600275A (es) |
HK (1) | HK1122731A1 (es) |
HN (1) | HN2006023741A (es) |
IL (1) | IL187901A0 (es) |
MA (1) | MA29560B1 (es) |
MX (1) | MX2007016238A (es) |
MY (1) | MY150069A (es) |
NO (1) | NO20080420L (es) |
NZ (1) | NZ564069A (es) |
PA (1) | PA8682701A1 (es) |
PE (1) | PE20070098A1 (es) |
TN (1) | TNSN07438A1 (es) |
TW (1) | TWI446934B (es) |
UA (1) | UA91553C2 (es) |
UY (1) | UY29637A1 (es) |
WO (1) | WO2007003746A1 (es) |
ZA (1) | ZA200711035B (es) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2090297A1 (en) * | 2008-02-13 | 2009-08-19 | Boehringer Ingelheim International GmbH | Formulations of flibanserin |
BR112014006124A2 (pt) * | 2011-09-14 | 2017-04-11 | Pozen Inc | dosagem faseada de clopidogrel |
IT201700011337A1 (it) * | 2017-02-02 | 2018-08-02 | S I I T S R L Servizio Int Imballaggi Termosaldanti | Compressa multistrato per la somministrazione di magnesio |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2655266B1 (fr) * | 1989-12-05 | 1992-04-03 | Smith Kline French Lab | Compositions pharmaceutiques a base de cimetidine. |
DE59303759C5 (de) * | 1992-01-17 | 2009-04-09 | Alfatec-Pharma Gmbh | Wirkstoff-enthaltende festkörper mit einem gerüst aus hydrophilen makromolekülen und verfahren zu ihrer herstellung |
EP1005863A1 (en) * | 1998-12-04 | 2000-06-07 | Synthelabo | Controlled-release dosage forms comprising a short acting hypnotic or a salt thereof |
AU3469100A (en) * | 1999-01-05 | 2000-07-24 | Copley Pharmaceutical Inc. | Sustained release formulation with reduced moisture sensitivity |
EP1064937A1 (en) * | 1999-06-28 | 2001-01-03 | Sanofi-Synthelabo | Timed dual release dosage forms comprising a short acting hypnotic or a salt thereof |
JP4933033B2 (ja) * | 2003-03-17 | 2012-05-16 | 武田薬品工業株式会社 | 放出制御組成物 |
WO2005044199A2 (en) * | 2003-11-05 | 2005-05-19 | Santarus, Inc. | Combination of proton pump inhibitor and sleep aid |
-
2005
- 2005-06-28 FR FR0506539A patent/FR2887455B1/fr not_active Expired - Fee Related
-
2006
- 2006-06-23 PA PA20068682701A patent/PA8682701A1/es unknown
- 2006-06-26 UA UAA200800914A patent/UA91553C2/ru unknown
- 2006-06-26 AU AU2006264856A patent/AU2006264856B2/en not_active Ceased
- 2006-06-26 MX MX2007016238A patent/MX2007016238A/es active IP Right Grant
- 2006-06-26 KR KR1020077030484A patent/KR101387839B1/ko active IP Right Grant
- 2006-06-26 EP EP06778663A patent/EP1904037A1/fr not_active Withdrawn
- 2006-06-26 BR BRPI0612990-0A patent/BRPI0612990A2/pt not_active Application Discontinuation
- 2006-06-26 EA EA200800150A patent/EA013745B1/ru not_active IP Right Cessation
- 2006-06-26 NZ NZ564069A patent/NZ564069A/en not_active IP Right Cessation
- 2006-06-26 DO DO2006000144A patent/DOP2006000144A/es unknown
- 2006-06-26 WO PCT/FR2006/001466 patent/WO2007003746A1/fr active Application Filing
- 2006-06-26 ZA ZA200711035A patent/ZA200711035B/xx unknown
- 2006-06-26 MY MYPI20063017A patent/MY150069A/en unknown
- 2006-06-26 CN CN2006800231372A patent/CN101217943B/zh active Active
- 2006-06-26 CA CA002611125A patent/CA2611125A1/fr not_active Abandoned
- 2006-06-26 JP JP2008518906A patent/JP2008546830A/ja active Pending
- 2006-06-27 HN HN2006023741A patent/HN2006023741A/es unknown
- 2006-06-27 GT GT200600275A patent/GT200600275A/es unknown
- 2006-06-27 AR ARP060102755A patent/AR057410A1/es unknown
- 2006-06-28 PE PE2006000753A patent/PE20070098A1/es active IP Right Grant
- 2006-06-28 TW TW095123267A patent/TWI446934B/zh not_active IP Right Cessation
- 2006-06-29 UY UY29637A patent/UY29637A1/es unknown
-
2007
- 2007-11-26 TN TNP2007000438A patent/TNSN07438A1/en unknown
- 2007-12-03 US US11/949,291 patent/US20080089936A1/en not_active Abandoned
- 2007-12-04 IL IL187901A patent/IL187901A0/en unknown
- 2007-12-06 CR CR9567A patent/CR9567A/es unknown
- 2007-12-13 EC EC2007008010A patent/ECSP078010A/es unknown
- 2007-12-24 MA MA30501A patent/MA29560B1/fr unknown
-
2008
- 2008-01-22 NO NO20080420A patent/NO20080420L/no not_active Application Discontinuation
- 2008-12-29 HK HK08114006.5A patent/HK1122731A1/xx unknown
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG | Grant, registration |