PE20061047A1 - COMPOSICION FARMACEUTICA QUE COMPRENDE UN PEPTIDO ß-AMILOIDE - Google Patents
COMPOSICION FARMACEUTICA QUE COMPRENDE UN PEPTIDO ß-AMILOIDEInfo
- Publication number
- PE20061047A1 PE20061047A1 PE2005001290A PE2005001290A PE20061047A1 PE 20061047 A1 PE20061047 A1 PE 20061047A1 PE 2005001290 A PE2005001290 A PE 2005001290A PE 2005001290 A PE2005001290 A PE 2005001290A PE 20061047 A1 PE20061047 A1 PE 20061047A1
- Authority
- PE
- Peru
- Prior art keywords
- pharmaceutical composition
- composition including
- composition
- amyloid peptide
- refers
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/385—Haptens or antigens, bound to carriers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/162—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0007—Nervous system antigens; Prions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
- A61K47/6901—Conjugates being cells, cell fragments, viruses, ghosts, red blood cells or viral vectors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5258—Virus-like particles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6031—Proteins
- A61K2039/6075—Viral proteins
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Organic Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Microbiology (AREA)
- Virology (AREA)
- Mycology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Zoology (AREA)
- Endocrinology (AREA)
- Dermatology (AREA)
- Hematology (AREA)
- Cell Biology (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Molecular Biology (AREA)
- Psychology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
SE REFIERE A UNA COMPOSICION FARMACEUTICA QUE COMPRENDE PROTEINAS CAPSIDES DE UN BACTERIFAGO DE ARN ENSAMBLADO A UNA PARTICULA TIPO VIRUS (VLP) QUIMICAMENTE ACOPLADAS A UN FRAGMENTO DEL PEPTIDO Ab-1-42 EN UNA CANTIDAD COMPRENDIDA ENTRE 5 ug A 300 ug. DICHA COMPOSICION EN SOLUCION ACUOSA TIENE UNA CONCENTRACION COMPRENDIDA ENTRE 0.25 A 0.75 mg/ml. TAMBIEN SE REFIERE A UNA MOLECULA DE UNION TAL COMO UN ANTICUERPO MONOCLONAL QUE PRESENTA AFINIDAD A Ab-1-42 CON UNA CONSTANTE DE DISOCIACION MENOR A 1000 mM. DICHA COMPOSICION ES UTIL EN EL TRATAMIENTO DE LA ENFERMEDAD DE ALZHEIMER, DEMENCIA
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB0424563A GB0424563D0 (en) | 2004-11-05 | 2004-11-05 | Organic compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
PE20061047A1 true PE20061047A1 (es) | 2006-11-07 |
Family
ID=33523293
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PE2005001290A PE20061047A1 (es) | 2004-11-05 | 2005-11-03 | COMPOSICION FARMACEUTICA QUE COMPRENDE UN PEPTIDO ß-AMILOIDE |
Country Status (25)
Country | Link |
---|---|
US (4) | US7867499B2 (es) |
EP (2) | EP1812050A1 (es) |
JP (2) | JP2008515954A (es) |
KR (1) | KR20070073882A (es) |
CN (1) | CN101048174A (es) |
AR (1) | AR054092A1 (es) |
AU (2) | AU2005300692A1 (es) |
BR (1) | BRPI0517682A (es) |
CA (1) | CA2581300A1 (es) |
EC (1) | ECSP077415A (es) |
GB (1) | GB0424563D0 (es) |
GT (1) | GT200500313A (es) |
IL (1) | IL182692A (es) |
MA (1) | MA29020B1 (es) |
MX (1) | MX2007005430A (es) |
MY (1) | MY148584A (es) |
NO (1) | NO20072743L (es) |
NZ (1) | NZ583688A (es) |
PE (1) | PE20061047A1 (es) |
RU (1) | RU2415677C2 (es) |
SG (1) | SG170646A1 (es) |
TN (1) | TNSN07166A1 (es) |
TW (1) | TWI380825B (es) |
WO (1) | WO2006048295A1 (es) |
ZA (1) | ZA200702369B (es) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB0424563D0 (en) * | 2004-11-05 | 2004-12-08 | Novartis Ag | Organic compounds |
PE20130642A1 (es) * | 2010-03-29 | 2013-06-19 | Novartis Ag | Composicion que comprende el peptido amiloide beta 1-6 acoplado a una particula similar a virus y un auxiliar |
CA3208643A1 (en) | 2021-01-18 | 2022-07-21 | Conserv Bioscience Limited | Coronavirus immunogenic compositions, methods and uses thereof |
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US5204096A (en) * | 1984-03-07 | 1993-04-20 | New York Blood Center, Inc. | Pre-S gene coded peptide hepatitis B immunogens, vaccines, diagnostics, and synthetic lipid vesicle carriers |
US4722840A (en) * | 1984-09-12 | 1988-02-02 | Chiron Corporation | Hybrid particle immunogens |
US4959314A (en) * | 1984-11-09 | 1990-09-25 | Cetus Corporation | Cysteine-depleted muteins of biologically active proteins |
DE3750176T2 (de) | 1986-09-22 | 1994-10-13 | Emory University, Atlanta, Ga. | Impfstoff und verfahren zur herstellung. |
US5143726A (en) * | 1986-12-09 | 1992-09-01 | The Scripps Research Institute | T cell epitopes of the hepatitis B virus nucleocapsid protein |
GB8903313D0 (en) | 1989-02-14 | 1989-04-05 | Wellcome Found | Conjugates |
GB8913737D0 (en) | 1989-06-15 | 1989-08-02 | Univ Birmingham | A novel anti-allergy treatment |
US5334394A (en) | 1990-06-22 | 1994-08-02 | The Regents Of The University Of California | Human immunodeficiency virus decoy |
US5178882A (en) | 1990-06-22 | 1993-01-12 | The Regents Of The University Of California | Viral decoy vaccine |
US5142726A (en) * | 1991-04-03 | 1992-09-01 | Mann Robert F | Adjustable bristle length toothbrush |
GB9114003D0 (en) * | 1991-06-28 | 1991-08-14 | Mastico Robert A | Chimaeric protein |
ZA934199B (en) | 1992-06-18 | 1994-01-10 | Akzo Nv | Carrier system against gnrh |
US6004763A (en) * | 1992-09-11 | 1999-12-21 | Institut Pasteur | Antigen-carrying microparticles and their use in the induction of humoral or cellular responses |
ES2148116T1 (es) * | 1992-10-13 | 2000-10-16 | Univ Duke | Metodos de detectar la enfermedad de alzheimer. |
CA2153391C (en) * | 1993-01-11 | 2000-08-15 | Kenneth Rock | Inducing cytotoxic t lymphocyte responses |
US6180771B1 (en) * | 1993-12-08 | 2001-01-30 | Immulogic Pharmaceutical Corp. | Nucleic acids encoding a house dust mite allergen, Der p III, and uses therefor |
US5935821A (en) * | 1995-01-17 | 1999-08-10 | Board Of Trustees Of The University Of Kentucky | Polynucleotides related to monoclonal antibody 1A7 and use for the treatment of melanoma and small cell carcinoma |
JPH09202735A (ja) | 1996-01-25 | 1997-08-05 | Nof Corp | リポソーム型アレルギー治療薬 |
US5786161A (en) * | 1996-06-06 | 1998-07-28 | Miltenyi Biotec. Gmbh | Isolation and characterization of allergen-binding cells for diagnosis of hypersensitivity |
SE9604815D0 (sv) | 1996-12-20 | 1996-12-20 | Pharmacia & Upjohn Ab | A metod of diagnosis |
EP1005368B1 (en) | 1997-03-10 | 2009-09-02 | Ottawa Hospital Research Institute | Use of nucleic acids containing unmethylated CpG dinucleotide in combination with alum as adjuvants |
US8173127B2 (en) * | 1997-04-09 | 2012-05-08 | Intellect Neurosciences, Inc. | Specific antibodies to amyloid beta peptide, pharmaceutical compositions and methods of use thereof |
AU743827B2 (en) | 1997-04-09 | 2002-02-07 | Intellect Neurosciences, Inc. | Recombinant antibodies specific for beta-amyloid ends, DNA encoding and methods of use thereof |
US6169175B1 (en) | 1997-08-06 | 2001-01-02 | Centers For Disease Control And Prevention | Preparation and use of recombinant influenza A virus M2 construct vaccines |
US6054312A (en) * | 1997-08-29 | 2000-04-25 | Selective Genetics, Inc. | Receptor-mediated gene delivery using bacteriophage vectors |
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US6743427B1 (en) * | 1997-12-02 | 2004-06-01 | Neuralab Limited | Prevention and treatment of amyloidogenic disease |
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US7128911B2 (en) * | 2001-01-19 | 2006-10-31 | Cytos Biotechnology Ag | Antigen arrays for treatment of bone disease |
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US7094409B2 (en) * | 2001-01-19 | 2006-08-22 | Cytos Biotechnology Ag | Antigen arrays for treatment of allergic eosinophilic diseases |
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EP1425040A2 (en) | 2001-09-14 | 2004-06-09 | Cytos Biotechnology AG | In vivo activation of antigen presenting cells for enhancement of immune responses induced by virus like particles |
US7115266B2 (en) * | 2001-10-05 | 2006-10-03 | Cytos Biotechnology Ag | Angiotensin peptide-carrier conjugates and uses thereof |
US20030219459A1 (en) * | 2002-01-18 | 2003-11-27 | Cytos Biotechnology Ag | Prion protein carrier-conjugates |
AU2003246690B2 (en) * | 2002-07-17 | 2010-03-11 | Cytos Biotechnology Ag | Molecular antigen arrays using a virus like particle derived from the AP205 coat protein |
BR0312297A (pt) * | 2002-07-18 | 2005-04-12 | Cytos Biotechnology Ag | Conjugados veìculos de hapteno e seu uso |
DE60329106D1 (de) * | 2002-07-19 | 2009-10-15 | Cytos Biotechnology Ag | Ghrelin-träger-konjugate |
KR101070078B1 (ko) * | 2002-07-19 | 2011-10-04 | 노파르티스 파르마 아게 | 아밀로이드 베타1-6 항원 어레이를 포함하는 백신 조성물 |
AU2003254914A1 (en) | 2002-08-12 | 2004-03-03 | Kyowa Hakko Kogyo Co., Ltd. | Amino acid-containing chewable |
TW200509968A (en) * | 2002-11-01 | 2005-03-16 | Elan Pharm Inc | Prevention and treatment of synucleinopathic disease |
TW200501962A (en) * | 2003-04-01 | 2005-01-16 | Novartis Ag | Use of carbamazepine derivatives for the treatment of agitation in dementia patients |
GB0424563D0 (en) * | 2004-11-05 | 2004-12-08 | Novartis Ag | Organic compounds |
-
2004
- 2004-11-05 GB GB0424563A patent/GB0424563D0/en not_active Ceased
-
2005
- 2005-10-28 MY MYPI20055090A patent/MY148584A/en unknown
- 2005-10-28 GT GT200500313A patent/GT200500313A/es unknown
- 2005-11-03 US US11/718,665 patent/US7867499B2/en not_active Expired - Fee Related
- 2005-11-03 PE PE2005001290A patent/PE20061047A1/es not_active Application Discontinuation
- 2005-11-03 MX MX2007005430A patent/MX2007005430A/es active IP Right Grant
- 2005-11-03 CA CA002581300A patent/CA2581300A1/en not_active Abandoned
- 2005-11-03 WO PCT/EP2005/011788 patent/WO2006048295A1/en active Application Filing
- 2005-11-03 EP EP05801760A patent/EP1812050A1/en not_active Withdrawn
- 2005-11-03 AR ARP050104609A patent/AR054092A1/es unknown
- 2005-11-03 BR BRPI0517682-4A patent/BRPI0517682A/pt not_active IP Right Cessation
- 2005-11-03 EP EP20100177232 patent/EP2286830A3/en not_active Withdrawn
- 2005-11-03 RU RU2007120689/15A patent/RU2415677C2/ru not_active IP Right Cessation
- 2005-11-03 SG SG200907306-5A patent/SG170646A1/en unknown
- 2005-11-03 NZ NZ583688A patent/NZ583688A/en not_active IP Right Cessation
- 2005-11-03 CN CNA2005800368845A patent/CN101048174A/zh active Pending
- 2005-11-03 JP JP2007536128A patent/JP2008515954A/ja not_active Withdrawn
- 2005-11-03 KR KR1020077010214A patent/KR20070073882A/ko not_active Application Discontinuation
- 2005-11-03 AU AU2005300692A patent/AU2005300692A1/en not_active Abandoned
- 2005-11-04 TW TW094138839A patent/TWI380825B/zh not_active IP Right Cessation
-
2007
- 2007-03-22 ZA ZA200702369A patent/ZA200702369B/xx unknown
- 2007-04-19 IL IL182692A patent/IL182692A/en not_active IP Right Cessation
- 2007-04-24 EC EC2007007415A patent/ECSP077415A/es unknown
- 2007-05-04 TN TNP2007000166A patent/TNSN07166A1/fr unknown
- 2007-05-14 MA MA29899A patent/MA29020B1/fr unknown
- 2007-05-30 NO NO20072743A patent/NO20072743L/no not_active Application Discontinuation
-
2010
- 2010-02-04 AU AU2010200410A patent/AU2010200410B2/en not_active Ceased
- 2010-12-17 US US12/971,534 patent/US8460676B2/en not_active Expired - Fee Related
-
2011
- 2011-05-02 JP JP2011102847A patent/JP2011157395A/ja active Pending
-
2013
- 2013-05-13 US US13/892,552 patent/US8617566B2/en not_active Expired - Fee Related
- 2013-11-20 US US14/085,048 patent/US20140079730A1/en not_active Abandoned
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