PE20040363A1 - Derivados de hidroxi tetrahidro-naftalenilurea - Google Patents

Derivados de hidroxi tetrahidro-naftalenilurea

Info

Publication number
PE20040363A1
PE20040363A1 PE2003000445A PE2003000445A PE20040363A1 PE 20040363 A1 PE20040363 A1 PE 20040363A1 PE 2003000445 A PE2003000445 A PE 2003000445A PE 2003000445 A PE2003000445 A PE 2003000445A PE 20040363 A1 PE20040363 A1 PE 20040363A1
Authority
PE
Peru
Prior art keywords
hydroxy
tetrahydro
naphthalenyl
naphthalenylurea
disorders
Prior art date
Application number
PE2003000445A
Other languages
English (en)
Inventor
Klaus Urbahns
Muneto Mogi
Nagahiro Yoshida
Toshio Kokubo
Hiroshi Fujishima
Mashiro Shiroo
Yasuhiro Tsujimi
Noriyuki Yamamoto
Masaomi Tajimi
Toshiya Moriwaki
Tsutomu Masuda
Takeshi Yura
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of PE20040363A1 publication Critical patent/PE20040363A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/28—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C275/32—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by singly-bound oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/17—Amides, e.g. hydroxamic acids having the group >N—C(O)—N< or >N—C(S)—N<, e.g. urea, thiourea, carmustine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/28—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C275/40—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by nitrogen atoms not being part of nitro or nitroso groups

Abstract

SE REFIERE A UN DERIVADO DE HIDROXI-TETRAHIDRO-NAFTALENILUREA, SUS FORMAS TAUTOMERICAS Y ESTEREOISOMERICA Y SALES DEL MISMO, DE FORMULA I, DONDE X ES (a) O (b); Y ES UN ENLACE DIRECTO; R1, R2 Y R3 SON H, HALOGENO, HIDROXI, ENTRE OTROS; Z1 ES H O ALQUILO C1-C6; Z2 ES H, HALOGENO O ALQUILO C1-C6. SON COMPUESTOS PREFERIDOS N-[4-CLORO-3-(TRIFLUOROMETIL)FENIL]-N'-(7-HIDROXI-5,6,7,8-TETRAHIDRO-1-NAFTALENIL)UREA, N-(3-CLOROFENIL)-N'-(7-HIDROXI-5,6,7,8-TETRAHIDRO-1-NAFTALENIL)UREA Y 3-({[(7-HIDROXI-5,6,7,8-TETRAHIDRO-1-NAFTALENIL)AMINO]CARBONIL}AMINO)BENZOATO DE ETILO; SE REFIERE TAMBIEN A COMPOSICIONES FARMACEUTICAS ANTAGONISTAS DE VR-1 UTILES EN EL TRATAMIENTO Y PROFILAXIS DE ENFERMEDADES ASOCIADAS A TRASTORNOS UROLOGICOS, TRASTORNOS RELACIONADOS A DOLOR, TRASTORNOS INFLAMATORIOS Y TRASTORNOS NEUROLOGICOS
PE2003000445A 2002-05-08 2003-05-07 Derivados de hidroxi tetrahidro-naftalenilurea PE20040363A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0210512.0A GB0210512D0 (en) 2002-05-08 2002-05-08 Tetrahydro-napthalene derivatives
GBGB0227262.3A GB0227262D0 (en) 2002-05-08 2002-11-21 Tetrahydro-naphthalene derivatives

Publications (1)

Publication Number Publication Date
PE20040363A1 true PE20040363A1 (es) 2004-07-03

Family

ID=9936269

Family Applications (1)

Application Number Title Priority Date Filing Date
PE2003000445A PE20040363A1 (es) 2002-05-08 2003-05-07 Derivados de hidroxi tetrahidro-naftalenilurea

Country Status (13)

Country Link
KR (1) KR101000688B1 (es)
AR (1) AR039983A1 (es)
CU (1) CU23422B7 (es)
DO (1) DOP2003000642A (es)
EC (1) ECSP045413A (es)
GB (2) GB0210512D0 (es)
GT (1) GT200300102A (es)
MA (1) MA30728B1 (es)
MY (1) MY155011A (es)
PE (1) PE20040363A1 (es)
PT (1) PT1506167E (es)
UA (1) UA77301C2 (es)
ZA (1) ZA200408993B (es)

Also Published As

Publication number Publication date
AR039983A1 (es) 2005-03-09
MA30728B1 (fr) 2009-10-01
KR20040108784A (ko) 2004-12-24
DOP2003000642A (es) 2003-11-15
CU23422B7 (es) 2009-09-08
ECSP045413A (es) 2005-01-03
GB0210512D0 (en) 2002-06-19
ZA200408993B (en) 2006-01-25
PT1506167E (pt) 2007-12-10
UA77301C2 (en) 2006-11-15
GT200300102A (es) 2004-03-17
MY155011A (en) 2015-08-28
KR101000688B1 (ko) 2010-12-10
GB0227262D0 (en) 2002-12-31

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Legal Events

Date Code Title Description
FG Grant, registration
FD Application declared void or lapsed