PE20040242A1 - Un derivado de piridina opticamente activo y un medicamento que lo contiene - Google Patents
Un derivado de piridina opticamente activo y un medicamento que lo contieneInfo
- Publication number
- PE20040242A1 PE20040242A1 PE2003000253A PE2003000253A PE20040242A1 PE 20040242 A1 PE20040242 A1 PE 20040242A1 PE 2003000253 A PE2003000253 A PE 2003000253A PE 2003000253 A PE2003000253 A PE 2003000253A PE 20040242 A1 PE20040242 A1 PE 20040242A1
- Authority
- PE
- Peru
- Prior art keywords
- pyridine derivative
- agent
- optically active
- product containing
- medicinal product
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/06—Anti-spasmodics, e.g. drugs for colics, esophagic dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/16—Emollients or protectives, e.g. against radiation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Physical Education & Sports Medicine (AREA)
- Dermatology (AREA)
- Rheumatology (AREA)
- Pulmonology (AREA)
- Pain & Pain Management (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Vascular Medicine (AREA)
- Hematology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Communicable Diseases (AREA)
- Ophthalmology & Optometry (AREA)
- Oncology (AREA)
- Neurology (AREA)
- Transplantation (AREA)
- Diabetes (AREA)
- Biomedical Technology (AREA)
- Toxicology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Abstract
SE REFIERE A UN DERIVADO DE PIRIDINA, CONSTITUIDO POR (-)-7-[2-(CICLOPROPILMETOXI)-6-HIDROXIFENIL]-5-[(3S)-3-PIPERIDINIL]-1,4-DIHIDRO-2H-PIRIDO[2,3-d][1,3]OXAZIN-2-ONA DE FORMULA (I) QUE TIENE UNA PUREZA OPTICA DE AL MENOS UN 90% DE EXCESO ENANTIOMERICO. UNA COMPOSICION FARMACEUTICA QUE LO CONTIENE. EL COMPUESTO ES UN INHIBIDOR DE LA QUINASA IkB Y ES UTIL PARA EL TRATAMIENTO Y PROFILAXIS DE EFERMEDADES QUE IMPLICAN LA ACTIVIDAD DE NF-kB, Y ACTUA COMO: a) UN AGENTE ANTIINFLAMATORIO UTIL PARA TRATAR O PREVENIR UNA ENFERMEDAD SELECCIONADA DEL GRUPO CONSTITUIDO POR ASMA,RINITIS ALERGICA, DERMATITIS ATOPICA, URTICARIA, CONJUNTIVITIS, CATARRO PRIMAVERAL, ARTROREUMATISMO CRONICO, LUPUS ERITEMATOSO SISTEMICO,PSORIASIS, COLITIS DIABROTICA,SINDROME DE RESPUESTA INFLAMATORIA SISTEMICA (SIRS), ENTRE OTROS. b) UN INMUNOSUPRESOR; c) UN AGENTE PARA TRATAR ISQUEMIA; d) UN AGENTE ANTITUMORAL
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2002070655A JP2003277383A (ja) | 2002-03-14 | 2002-03-14 | 光学活性ピリジン誘導体およびそれを含む医薬 |
Publications (1)
Publication Number | Publication Date |
---|---|
PE20040242A1 true PE20040242A1 (es) | 2004-05-15 |
Family
ID=27800344
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PE2003000253A PE20040242A1 (es) | 2002-03-14 | 2003-03-13 | Un derivado de piridina opticamente activo y un medicamento que lo contiene |
Country Status (13)
Country | Link |
---|---|
US (2) | US7375103B2 (es) |
EP (1) | EP1487842B1 (es) |
JP (2) | JP2003277383A (es) |
AR (1) | AR038950A1 (es) |
AU (1) | AU2003215624A1 (es) |
CA (1) | CA2478942A1 (es) |
DE (1) | DE60312494T2 (es) |
ES (1) | ES2283795T3 (es) |
HN (1) | HN2003000098A (es) |
PE (1) | PE20040242A1 (es) |
TW (1) | TW200403247A (es) |
UY (1) | UY27719A1 (es) |
WO (1) | WO2003076447A1 (es) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE102005036655A1 (de) * | 2005-08-04 | 2007-02-08 | Bayer Healthcare Ag | Behandlung von Tumoren mit IKK-ß Inhibitoren |
US8426355B2 (en) | 2006-03-15 | 2013-04-23 | Theralogics, Inc. | Methods of treating muscular wasting diseases using NF-κB activation inhibitors |
WO2008044339A1 (fr) * | 2006-10-13 | 2008-04-17 | Aqumen Biopharmaceuticals K.K. | Agent thérapeutique/de prévention contenant un composé de statine, utilisé pour une maladie intraoculaire |
CN104491864A (zh) | 2008-04-21 | 2015-04-08 | 奥德纳米有限公司 | 用于治疗耳部疾病和病况的耳用调配物及方法 |
US11969501B2 (en) | 2008-04-21 | 2024-04-30 | Dompé Farmaceutici S.P.A. | Auris formulations for treating otic diseases and conditions |
AP2015008750A0 (en) * | 2013-04-08 | 2015-09-30 | Bayer Pharma AG | Use of substituted 2,3-dihydroimidazo[1,2-c] quinazolines for treating lymphomas |
US20180289685A1 (en) | 2015-04-30 | 2018-10-11 | Bayer Pharma Aktiengesellschaft | Combinations of inhibitors of irak4 with inhibitors of btk |
WO2017148902A1 (de) | 2016-03-03 | 2017-09-08 | Bayer Pharma Aktiengesellschaft | Neue 2-substituierte indazole, verfahren zu ihrer herstellung, pharmazeutische präparate die diese enthalten, sowie deren verwendung zur herstellung von arzneimitteln |
AU2017290256A1 (en) | 2016-06-29 | 2019-01-17 | Otonomy, Inc. | Triglyceride otic formulations and uses thereof |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP4272338B2 (ja) * | 2000-09-22 | 2009-06-03 | バイエル アクチェンゲゼルシャフト | ピリジン誘導体 |
-
2002
- 2002-03-14 JP JP2002070655A patent/JP2003277383A/ja active Pending
-
2003
- 2003-03-03 WO PCT/EP2003/002169 patent/WO2003076447A1/en active IP Right Grant
- 2003-03-03 JP JP2003574663A patent/JP2005526074A/ja active Pending
- 2003-03-03 ES ES03743829T patent/ES2283795T3/es not_active Expired - Lifetime
- 2003-03-03 DE DE60312494T patent/DE60312494T2/de not_active Expired - Fee Related
- 2003-03-03 US US10/508,107 patent/US7375103B2/en not_active Expired - Fee Related
- 2003-03-03 CA CA002478942A patent/CA2478942A1/en not_active Abandoned
- 2003-03-03 AU AU2003215624A patent/AU2003215624A1/en not_active Abandoned
- 2003-03-03 EP EP03743829A patent/EP1487842B1/en not_active Expired - Fee Related
- 2003-03-12 UY UY27719A patent/UY27719A1/es not_active Application Discontinuation
- 2003-03-12 AR ARP030100859A patent/AR038950A1/es not_active Application Discontinuation
- 2003-03-13 TW TW092105417A patent/TW200403247A/zh unknown
- 2003-03-13 HN HN2003000098A patent/HN2003000098A/es unknown
- 2003-03-13 PE PE2003000253A patent/PE20040242A1/es not_active Application Discontinuation
-
2008
- 2008-05-19 US US12/123,405 patent/US20090054424A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
TW200403247A (en) | 2004-03-01 |
DE60312494T2 (de) | 2007-11-29 |
WO2003076447A1 (en) | 2003-09-18 |
JP2003277383A (ja) | 2003-10-02 |
HN2003000098A (es) | 2003-12-15 |
UY27719A1 (es) | 2003-10-31 |
DE60312494D1 (de) | 2007-04-26 |
EP1487842B1 (en) | 2007-03-14 |
US20050215547A1 (en) | 2005-09-29 |
EP1487842A1 (en) | 2004-12-22 |
JP2005526074A (ja) | 2005-09-02 |
AR038950A1 (es) | 2005-02-02 |
CA2478942A1 (en) | 2003-09-18 |
US7375103B2 (en) | 2008-05-20 |
ES2283795T3 (es) | 2007-11-01 |
AU2003215624A1 (en) | 2003-09-22 |
US20090054424A1 (en) | 2009-02-26 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FA | Abandonment or withdrawal |