PE20040084A1 - Combinaciones de medicamentos que contienen compuestos heterociclicos y un nuevo agente anticolinergico - Google Patents
Combinaciones de medicamentos que contienen compuestos heterociclicos y un nuevo agente anticolinergicoInfo
- Publication number
- PE20040084A1 PE20040084A1 PE2003000366A PE2003000366A PE20040084A1 PE 20040084 A1 PE20040084 A1 PE 20040084A1 PE 2003000366 A PE2003000366 A PE 2003000366A PE 2003000366 A PE2003000366 A PE 2003000366A PE 20040084 A1 PE20040084 A1 PE 20040084A1
- Authority
- PE
- Peru
- Prior art keywords
- phenyl
- ethyl
- containing heterocyclic
- heterocyclic compounds
- drug combinations
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
- C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
- C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
- C07D451/06—Oxygen atoms
- C07D451/10—Oxygen atoms acylated by aliphatic or araliphatic carboxylic acids, e.g. atropine, scopolamine
Abstract
SE REFIERE A UNA SAL DE FORMULA I DONDE X- ES UN ANION MONOCARGADO NEGATIVAMENTE SELECCIONADO DEL GRUPO DE Cl, Br, I, METANOSULFONATO, NITRATO, MALEATO, FUMARATO ENTRE OTROS EN COMBINACION CON UN COMPUESTO DE FORMULA II DONDE R1 ES H, METILO, ETILO, n-BUTILO, i-BUTILO, FENILO, 2-ETILFENILO, BENCILO, ENTRE OTROS; R2 ES H, METILO, ETILO O JUNTO CON R1, UN PUENTE BUTILENO O PENTILENO; R3 ES H; R4 ES METOXI; R5 ES CICLOHEXILO, FENILO, 3-METOXICARBONILFENILO, 4-METOXICARBONILFENILO, 3-CARBOXIFENILO, 4-CARBOXIFENILO, CN, -COOH, ENTRE OTROS; A ES O, -CH2-; B ES O, -C(R12)(R13)-, ENTRE OTROS; D ES -CH2-CH2-, -CH(Ph)-CH2-, -CONH-, -CO-CH2, ENTRE OTROS; R12 ES H, METILO, ETILO, I-PROPILO, FENILO ENTRE OTROS; R13 ES H O, JUNTO CON R2, UN ENLACE SENCILLO O UN PUENTE BUTILENO. LA COMBINACION MENCIONADA PUEDE ESTAR CONTENIDA EN UNA UNICA FORMA DE ADMINISTRACION O EN DOS FORMAS DE ADMINISTRACION SEPARADAS Y SON UTILES PARA EL TRATAMIENTO DE ENFERMEDADES DE LAS VIAS RESPIRATORIAS
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE10216427A DE10216427A1 (de) | 2002-04-12 | 2002-04-12 | Arzneimittelkompositionen enthaltend heterocyclische Verbindungen und ein neues Anticholinergikum |
Publications (1)
Publication Number | Publication Date |
---|---|
PE20040084A1 true PE20040084A1 (es) | 2004-04-01 |
Family
ID=28458800
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PE2003000366A PE20040084A1 (es) | 2002-04-12 | 2003-04-10 | Combinaciones de medicamentos que contienen compuestos heterociclicos y un nuevo agente anticolinergico |
Country Status (8)
Country | Link |
---|---|
US (1) | US20040002502A1 (es) |
AR (1) | AR039404A1 (es) |
AU (1) | AU2003221562A1 (es) |
DE (1) | DE10216427A1 (es) |
PE (1) | PE20040084A1 (es) |
TW (1) | TW200406209A (es) |
UY (1) | UY27759A1 (es) |
WO (1) | WO2003087049A2 (es) |
Families Citing this family (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7084153B2 (en) * | 2002-04-12 | 2006-08-01 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Medicaments comprising steroids and a novel anticholinergic |
US7417051B2 (en) * | 2002-04-12 | 2008-08-26 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Medicaments comprising betamimetics and a novel anticholinergic |
US20040058950A1 (en) * | 2002-07-09 | 2004-03-25 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Pharmaceutical compositions based on anticholinergics and PDE-IV inhibitors |
US20040048886A1 (en) * | 2002-07-09 | 2004-03-11 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Pharmaceutical compositions based on new anticholinergics and NK1 receptor antagonists |
US20040048887A1 (en) * | 2002-07-09 | 2004-03-11 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Pharmaceutical compositions based on anticholinergics and EGFR kinase inhibitors |
US20040044020A1 (en) * | 2002-07-09 | 2004-03-04 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Pharmaceutical compositions based on novel anticholinergics and p38 kinase inhibitors |
US20040166065A1 (en) | 2002-08-14 | 2004-08-26 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Aerosol formulation for inhalation comprising an anticholinergic |
US7244742B2 (en) * | 2002-08-17 | 2007-07-17 | Boehringer Ingelheim Pharma Gmbh & Co Kg | Pharmaceutical compositions for inhalation containing an anticholinergic, corticosteroid and betamimetic |
US8603296B2 (en) | 2002-10-07 | 2013-12-10 | Georgia-Pacific Consumer Products Lp | Method of making a fabric-creped absorbent cellulosic sheet with improved dispensing characteristics |
US7494563B2 (en) | 2002-10-07 | 2009-02-24 | Georgia-Pacific Consumer Products Lp | Fabric creped absorbent sheet with variable local basis weight |
US7056916B2 (en) | 2002-11-15 | 2006-06-06 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Medicaments for the treatment of chronic obstructive pulmonary disease |
US7332175B2 (en) * | 2003-05-27 | 2008-02-19 | Boehringer Ingelheim International Gmbh | Long-acting drug combinations for the treatment of respiratory complaints |
EP1504756A1 (en) * | 2003-08-06 | 2005-02-09 | Kyowa Hakko Kogyo Co., Ltd | Medicament compositions comprising a heterocyclic compound and an anticholinergic |
DE10345065A1 (de) * | 2003-09-26 | 2005-04-14 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Aerosolformulierung für die Inhalation enthaltend ein Anticholinergikum |
US20050272726A1 (en) * | 2004-04-22 | 2005-12-08 | Boehringer Ingelheim International Gmbh | Novel medicaments for the treatment of respiratory diseases |
US7220742B2 (en) * | 2004-05-14 | 2007-05-22 | Boehringer Ingelheim International Gmbh | Enantiomerically pure beta agonists, process for the manufacture thereof and use thereof as medicaments |
US20050255050A1 (en) * | 2004-05-14 | 2005-11-17 | Boehringer Ingelheim International Gmbh | Powder formulations for inhalation, comprising enantiomerically pure beta agonists |
JP5270343B2 (ja) * | 2005-08-15 | 2013-08-21 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | ベータミメティックスの製造方法 |
US7599861B2 (en) | 2006-03-02 | 2009-10-06 | Convergys Customer Management Group, Inc. | System and method for closed loop decisionmaking in an automated care system |
US8379830B1 (en) | 2006-05-22 | 2013-02-19 | Convergys Customer Management Delaware Llc | System and method for automated customer service with contingent live interaction |
US7809663B1 (en) | 2006-05-22 | 2010-10-05 | Convergys Cmg Utah, Inc. | System and method for supporting the utilization of machine language |
Family Cites Families (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2540633A1 (de) * | 1975-09-12 | 1977-04-28 | Boehringer Sohn Ingelheim | Neue quartaere n-beta-substituierte benzilsaeure-n-alkyl-nortropinester und verfahren zu deren herstellung |
US5770738A (en) * | 1992-03-05 | 1998-06-23 | Boehringer Ingelheim Kg | Esters of bi- and tricyclic amino alcohols, their preparation and their use in pharmaceutical compositions |
JP4172817B2 (ja) * | 1995-05-19 | 2008-10-29 | 協和醗酵工業株式会社 | 含酸素複素環化合物 |
DE19921693A1 (de) * | 1999-05-12 | 2000-11-16 | Boehringer Ingelheim Pharma | Neuartige Arzneimittelkompositionen auf der Basis von anticholinergisch wirksamen Verbindungen und ß-Mimetika |
US6706726B2 (en) * | 2000-10-14 | 2004-03-16 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Anticholinergics which may be used as medicaments as well as processes for preparing them |
US20020193393A1 (en) * | 2001-03-07 | 2002-12-19 | Michel Pairet | Pharmaceutical compositions based on anticholinergics and PDE-IV inhibitors |
DE10200943A1 (de) * | 2002-01-12 | 2003-07-24 | Boehringer Ingelheim Pharma | Verfahren zur Herstellung von Scopinestern |
US7084153B2 (en) * | 2002-04-12 | 2006-08-01 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Medicaments comprising steroids and a novel anticholinergic |
US7417051B2 (en) * | 2002-04-12 | 2008-08-26 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Medicaments comprising betamimetics and a novel anticholinergic |
US20040048887A1 (en) * | 2002-07-09 | 2004-03-11 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Pharmaceutical compositions based on anticholinergics and EGFR kinase inhibitors |
US20040048886A1 (en) * | 2002-07-09 | 2004-03-11 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Pharmaceutical compositions based on new anticholinergics and NK1 receptor antagonists |
US20040044020A1 (en) * | 2002-07-09 | 2004-03-04 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Pharmaceutical compositions based on novel anticholinergics and p38 kinase inhibitors |
US20040058950A1 (en) * | 2002-07-09 | 2004-03-25 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Pharmaceutical compositions based on anticholinergics and PDE-IV inhibitors |
US20040166065A1 (en) * | 2002-08-14 | 2004-08-26 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Aerosol formulation for inhalation comprising an anticholinergic |
US7244742B2 (en) * | 2002-08-17 | 2007-07-17 | Boehringer Ingelheim Pharma Gmbh & Co Kg | Pharmaceutical compositions for inhalation containing an anticholinergic, corticosteroid and betamimetic |
US7332175B2 (en) * | 2003-05-27 | 2008-02-19 | Boehringer Ingelheim International Gmbh | Long-acting drug combinations for the treatment of respiratory complaints |
US7273603B2 (en) * | 2003-07-11 | 2007-09-25 | Boehringer Ingelheim International Gmbh | HFC solution formulations containing an anticholinergic |
TWI259994B (en) * | 2003-07-21 | 2006-08-11 | Ali Corp | Adaptive multiple levels step-sized method for time scaling |
DE10345065A1 (de) * | 2003-09-26 | 2005-04-14 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Aerosolformulierung für die Inhalation enthaltend ein Anticholinergikum |
US20050154006A1 (en) * | 2004-01-09 | 2005-07-14 | Boehringer Ingelheim International Gmbh | Pharmaceutical compositions based on a scopineester and nicotinamide derivatives |
US20050186175A1 (en) * | 2004-02-20 | 2005-08-25 | Boehringer Ingelheim International Gmbh | Pharmaceutical compositions based on benzilic acid esters and soluble TNF receptor fusion proteins |
-
2002
- 2002-04-12 DE DE10216427A patent/DE10216427A1/de not_active Withdrawn
-
2003
- 2003-04-08 US US10/409,402 patent/US20040002502A1/en not_active Abandoned
- 2003-04-09 AU AU2003221562A patent/AU2003221562A1/en not_active Abandoned
- 2003-04-09 WO PCT/EP2003/003670 patent/WO2003087049A2/de not_active Application Discontinuation
- 2003-04-10 PE PE2003000366A patent/PE20040084A1/es not_active Application Discontinuation
- 2003-04-10 UY UY27759A patent/UY27759A1/es not_active Application Discontinuation
- 2003-04-10 TW TW092108228A patent/TW200406209A/zh unknown
- 2003-04-11 AR ARP030101265A patent/AR039404A1/es not_active Suspension/Interruption
Also Published As
Publication number | Publication date |
---|---|
TW200406209A (en) | 2004-05-01 |
AU2003221562A1 (en) | 2003-10-27 |
US20040002502A1 (en) | 2004-01-01 |
WO2003087049A3 (de) | 2004-02-05 |
AR039404A1 (es) | 2005-02-16 |
UY27759A1 (es) | 2003-11-28 |
DE10216427A1 (de) | 2003-10-23 |
AU2003221562A8 (en) | 2003-10-27 |
WO2003087049A2 (de) | 2003-10-23 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FA | Abandonment or withdrawal |