PE20030711A1 - Metodo para la produccion de carotenoides asimetricos - Google Patents

Metodo para la produccion de carotenoides asimetricos

Info

Publication number
PE20030711A1
PE20030711A1 PE2002001110A PE2002001110A PE20030711A1 PE 20030711 A1 PE20030711 A1 PE 20030711A1 PE 2002001110 A PE2002001110 A PE 2002001110A PE 2002001110 A PE2002001110 A PE 2002001110A PE 20030711 A1 PE20030711 A1 PE 20030711A1
Authority
PE
Peru
Prior art keywords
host cell
carotenoids
nucleic acid
isolated nucleic
asymmetric
Prior art date
Application number
PE2002001110A
Other languages
English (en)
Inventor
Luan Tao
Qiong Cheng
Original Assignee
Du Pont
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Du Pont filed Critical Du Pont
Publication of PE20030711A1 publication Critical patent/PE20030711A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P23/00—Preparation of compounds containing a cyclohexene ring having an unsaturated side chain containing at least ten carbon atoms bound by conjugated double bonds, e.g. carotenes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

SE REFIERE A UN METODO PARA LA PRODUCCION DE COMPUESTOS CAROTENOIDES ASIMETRICOS QUE COMPRENDE: a) PROVEER UNA CELULA HUESPED QUE PRODUCE CAROTENOIDES ACICLICOS CON POR LO MENOS UN GRUPO DE EXTREMO EN DONDE DICHA CELULA HUESPED EXPRESA UNA ß-CICLASA DE LICOPENO, SELECCIONADA DEL GRUPO DE i) UNA MOLECULA DE ACIDO NUCLEICO AISLADA QUE CODIFICA LA SECUENCIA DE AMINOACIDOS SELECCIONADA DE SEC.ID NO:2 Y SEC.ID NO:4; ii) UNA MOLECULA DE ACIDO NUCLEICO AISLADA QUE SE HIBRIDA CON (i) BAJO CONDICIONES DE HIBRIDACION, iii) UNA MOLECULA DE ACIDO NUCLEICO AISLADA QUE CODIFICA UN POLIPEPTIDO QUE TIENE POR LO MENOS UNA IDENTIDAD DEL 70% PARA LOS POLIPEPTIDOS SELECCIONADOS DEL GRUPO CONSISTENTE DE SEC ID NO:2 Y SEC ID NO.4 EN BASE AL METODO DE ALINEACION DE SMITH-WATERMAN; b) DESARROLLAR LA CELULA HUESPED BAJO CONDICIONES POR LAS CUALES SE PRODUCEN LOS CAROTENOIDES ASIMETRICOS; c) RECUPERAR DICHOS CAROTENIDES. LA CELULA HUESPED SE SELECCIONA DEL GRUPO DE ASPERGILLUS, TRICHODERMA, SACCHAROMYCES, CANDIDA, SALMONELLA, BACILLUS ENTRE OTRAS. EL CAROTENOIDE ACICLICO SE SELECCIONA DE LICOPENO, NEUROSPENO, DIDEHIDROLICOPENO, LICOXANTINA, HIDROXILICOPENO, ENTRE OTROS. LA INVENCION PROVEE CELULAS HUESPED TRANSFORMADAS QUE EXPRESAN LOS GENES PRESENTES Y METODOS PARA LA BIO-CONVERSION DE SUBSTRATOS DE CAROTENOIDES ACICLICOS A LOS CORRESPONDIENTES CAROTENOIDES ASIMETRICOS
PE2002001110A 2001-11-20 2002-11-20 Metodo para la produccion de carotenoides asimetricos PE20030711A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US33183001P 2001-11-20 2001-11-20

Publications (1)

Publication Number Publication Date
PE20030711A1 true PE20030711A1 (es) 2003-09-16

Family

ID=23295544

Family Applications (1)

Application Number Title Priority Date Filing Date
PE2002001110A PE20030711A1 (es) 2001-11-20 2002-11-20 Metodo para la produccion de carotenoides asimetricos

Country Status (8)

Country Link
US (1) US7063955B2 (es)
EP (1) EP1446491A4 (es)
JP (1) JP2005511034A (es)
AU (1) AU2002343754A1 (es)
CA (1) CA2468096A1 (es)
NO (1) NO20042202L (es)
PE (1) PE20030711A1 (es)
WO (1) WO2003044205A1 (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060088904A1 (en) * 2004-10-01 2006-04-27 Lockwood Samuel F Methods for the synthesis of astaxanthin
EP1866428A2 (en) 2005-03-18 2007-12-19 Microbia, Inc. Production of carotenoids in oleaginous yeast and fungi
US8691555B2 (en) 2006-09-28 2014-04-08 Dsm Ip Assests B.V. Production of carotenoids in oleaginous yeast and fungi
US20090093015A1 (en) * 2007-10-09 2009-04-09 Kemin Foods, L.C. Beta-cryptoxanthin production using a novel lycopene beta-monocyclase gene
EP2210935A1 (en) * 2009-01-19 2010-07-28 Deinove Methods for isolating bacteria
CN110819646A (zh) * 2018-08-09 2020-02-21 南京农业大学 一种与胡萝卜类胡萝卜素合成相关的DcLCYB1基因序列及其应用

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5429939A (en) * 1989-04-21 1995-07-04 Kirin Beer Kabushiki Kaisha DNA sequences useful for the synthesis of carotenoids
EP0471056B1 (en) * 1990-03-02 2001-10-17 BP Corporation North America Inc. Biosynthesis of carotenoids in genetically engineered hosts
US5545816A (en) * 1990-03-02 1996-08-13 Amoco Corporation Phytoene biosynthesis in genetically engineered hosts
US5530189A (en) * 1990-03-02 1996-06-25 Amoco Corporation Lycopene biosynthesis in genetically engineered hosts
US5530188A (en) * 1990-03-02 1996-06-25 Amoco Corporation Beta-carotene biosynthesis in genetically engineered hosts
US5792903A (en) 1993-10-25 1998-08-11 Yissum Research Development Company Of Hebrew University Of Jerusalem Lycopene cyclase gene
US5744341A (en) * 1996-03-29 1998-04-28 University Of Maryland College Park Genes of carotenoid biosynthesis and metabolism and a system for screening for such genes
WO2001066703A1 (en) 2000-03-07 2001-09-13 Cargill, Incorporated Production of lutein in microorganisms
EP1360313A4 (en) 2000-11-22 2004-08-04 Cargill Inc CAROTENOID BIOSYNTHESIS
JP2004528839A (ja) 2001-01-26 2004-09-24 カーギル，インコーポレーテッド カロテノイド生合成
US7034140B2 (en) * 2001-04-24 2006-04-25 E.I. Du Pont De Nemours And Company Genes involved in isoprenoid compound production

Also Published As

Publication number Publication date
CA2468096A1 (en) 2003-05-30
JP2005511034A (ja) 2005-04-28
EP1446491A1 (en) 2004-08-18
WO2003044205A1 (en) 2003-05-30
US20030143660A1 (en) 2003-07-31
NO20042202L (no) 2004-08-19
EP1446491A4 (en) 2006-02-15
US7063955B2 (en) 2006-06-20
AU2002343754A1 (en) 2003-06-10

Similar Documents

Publication Publication Date Title
CO5601037A2 (es) Anticuerpos anti-a beta y sus usos
ATE310090T1 (de) Gereinigte coprinus laccasen und nukleinsäuren welche dafür kodieren
PH12019501335A1 (en) Thermostable cas9 nucleases
BR9814404A (pt) " clonagem de expressão em fungos filamentosos "
DK1419255T3 (da) En ny gruppe af alfa-amylaser såvel som en fremgangsmåde til at identificere og udvinde nye alfa-amylaser.
AR002832A1 (es) Haloperoxidasas obtenidas de curvularia verruculosa, acidos nucleicos que las codifican, vector recombinante, celula huesped recombinante, metodos paraproducir dichas haloperoxidasas, metodo para oxidar un ion haluro, metodo para halogenar un compuesto y metodo para matar celulas microbianas o inhibir su
ES2422291T3 (es) Meganucleasas monocatenarias diseñadas racionalmente con secuencias de reconocimiento no palindrómicas
AR049177A1 (es) Polipeptidos y conjugados de interferon-alfa
DE60328715D1 (de) Polypeptide mit cellobiohydrolase ii-aktivität und dafür kodierende polynucleotide
BR9813608B1 (pt) célula hospedeira de bacillus transgênica, e, processo para produzir um polipeptìdeo tendo atividade aminopeptidase.
AR083848A1 (es) Polipeptidos con actividad de fosfolipasa c y polinucleotidos que los codifican
AR016223A1 (es) Fragmento aislado de acidos nucleicos que codifica enzimas de la biosintesis de carotenoides, gen quimerico, celula huesped transformada, polipeptido,metodos para alterar el nivel de expresion de dichas enzimas, metodos para obtener dicho fragmento, productos que se obtienen por dichos metodos y met
ATE323770T1 (de) Polypeptide mit lysophospholipaseaktivität und nukleinesäuren die sie kodieren
BRPI0416912A (pt) ácido nucleico isolado, método para preparar uma sesquiterpeno sintase funcional variante, sintase, polipeptìdeo, vetor, célula hospedeira, organismo não humano, e, métodos para produzir uma célula hospedeira recombinante, uma sesquiterpeno sintase, e pelo menos um terpenóide
DK1675956T3 (da) Minimal DNA-sekvens, der virksom som chromatinisolator, og dennes anvendelse til proteinekspression
ES2200728T1 (es) Clonacion y expresion de una lipasa extracelular acidorresistente de yarrowia lipolytica.
PE20030711A1 (es) Metodo para la produccion de carotenoides asimetricos
AR069054A1 (es) Polinucleotidos que codifican glutamato descarboxilasa (gad) y metodos para el mejoramiento de plantas
HUP0303517A2 (hu) Hímfertilitást közvetítő nukleotidszekvenciák és alkalmazásuk
CO2017011431A2 (es) Proteínas de fusión de receptor de factor de crecimiento epidermal variante iii - mesotelina
BRPI0410562B8 (pt) proteína de veículo e seu método de produção em uma planta, ácido nucleico isolado, vetor de expressão e célula hospedeira
DK0981631T3 (da) Polypeptider, som har aminopeptidase-aktivitet, og nukleinsyrer, som koder for samme
AR011994A1 (es) Secuencia aislada de acidos nucleicos, vector para la distribucion de dicha secuencia aislada de acidos nucleicos, celula huesped, planta y metodo
DK1756273T3 (da) Signalpeptid til frembringelse af et polypeptid
BR112021026326A2 (pt) Sacarose fosforilase engenheirada, composição, sequência de polinucleotídeo, vetor de expressão, célula hospedeira, e, método para produzir uma sacarose fosforilase engenheirada

Legal Events

Date Code Title Description
FD Application declared void or lapsed