PE20000539A1 - Secuencia del gen relacionado con angiopoyetina scarface 3 - Google Patents

Secuencia del gen relacionado con angiopoyetina scarface 3

Info

Publication number
PE20000539A1
PE20000539A1 PE1999000465A PE00046599A PE20000539A1 PE 20000539 A1 PE20000539 A1 PE 20000539A1 PE 1999000465 A PE1999000465 A PE 1999000465A PE 00046599 A PE00046599 A PE 00046599A PE 20000539 A1 PE20000539 A1 PE 20000539A1
Authority
PE
Peru
Prior art keywords
scarface
sequence
amino acids
angiopoyetin
refers
Prior art date
Application number
PE1999000465A
Other languages
English (en)
Inventor
Georg Heuer Josef
Ann Leonard Rebecca
Gene Burgett Stanley
Raghavacharya Sankhavaram Patanjali
Robert Rosteck Junior Paul
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of PE20000539A1 publication Critical patent/PE20000539A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/515—Angiogenesic factors; Angiogenin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2799/00—Uses of viruses
    • C12N2799/02—Uses of viruses as vector
    • C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
    • C12N2799/027—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from a retrovirus

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Vascular Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

SE REFIERE A UNA PROTEINA PURA CON ACTIVIDAD SCARFACE 3 QUE TIENE a)UNA SECUENCIA DE AMINOACIDOS CON UNA IDENTIDAD DE AL MENOS 70% CON LA SECUENCIA ID N° 2 DE 460 AMINOACIDOS; b)UNA SECUENCIA DE AMINOACIDOS QUE ES CODIFICADA POR UNA SECUENCIA DE ACIDO NUCLEICO QUE SE HIBRIDA CON UNA SECUENCIA N°1 DE 1380 PARES DE BASES EN CONDICIONES ALTAMENTE RESTRICTIVAS. TAMBIEN SE REFIERE A UN ANALOGO DE SCARFACE 3 QUE TIENE UNA SECUENCIA DE 460 AMINOACIDOS; Y A ACIDOS NUCLEICOS QUE CODIFICAN LA PROTEINA; A UN PLASMIDO; CELULA HUESPED. LAS PROTEINAS SCARFACE (DE DROSOPHILA) ESTAN RELACIONADAS CON PROTEINAS DE MAMIFERO TAL COMO LA ANGIOPOYETINA, LAS QUE SON NECESARIAS PARA LA ANGIOGENESIS NORMAL O FORMACION DE LA RED VASCULAR POR LO QUE PUEDE SER UTIL PARA EL TRATAMIENTO DE TUMORES MALIGNOS Y NO MALIGNOS, PREVENIR EL CRECIMIENTO TUMORAL, TRATAMIENTO DE LEUCEMIAS Y LA SUPRESION DE CELULAS MADRES HEMATOPOYETICAS ANTES O DURANTE LA QUIMIOTERAPIA Y RADIOTERAPIA
PE1999000465A 1998-06-02 1999-06-01 Secuencia del gen relacionado con angiopoyetina scarface 3 PE20000539A1 (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US8771698P 1998-06-02 1998-06-02
US11062098P 1998-12-02 1998-12-02
US12906599P 1999-04-13 1999-04-13
US13038199P 1999-04-21 1999-04-21

Publications (1)

Publication Number Publication Date
PE20000539A1 true PE20000539A1 (es) 2000-07-05

Family

ID=27492162

Family Applications (1)

Application Number Title Priority Date Filing Date
PE1999000465A PE20000539A1 (es) 1998-06-02 1999-06-01 Secuencia del gen relacionado con angiopoyetina scarface 3

Country Status (7)

Country Link
EP (1) EP0962466A1 (es)
AR (1) AR019851A1 (es)
AU (1) AU4227799A (es)
CO (1) CO5060478A1 (es)
PE (1) PE20000539A1 (es)
SV (1) SV1999000069A (es)
WO (1) WO1999062956A1 (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6030831A (en) * 1997-09-19 2000-02-29 Genetech, Inc. Tie ligand homologues
MXPA01006330A (es) * 1998-12-22 2002-07-02 Genentech Inc Metodos y composiciones para inhibir el crecimiento de celulas neoplasticas.
KR100553300B1 (ko) * 1999-03-08 2006-02-20 제넨테크, 인크. 혈관신생 및 심혈관형성의 촉진 또는 억제 방법
JP2003505350A (ja) * 1999-07-20 2003-02-12 ジェネンテック・インコーポレーテッド 免疫関連疾患の治療のための組成物と方法
KR20020062652A (ko) * 1999-12-09 2002-07-26 상꾜 가부시키가이샤 고지혈증의 치료 또는 예방제의 시험방법

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69633121T2 (de) * 1995-04-06 2005-07-28 Regeneron Pharmaceuticals, Inc. Tie-2 liganden, herstellungsverfahren und verwendung
US6057435A (en) * 1997-09-19 2000-05-02 Genentech, Inc. Tie ligand homologues
US6030831A (en) * 1997-09-19 2000-02-29 Genetech, Inc. Tie ligand homologues

Also Published As

Publication number Publication date
WO1999062956A1 (en) 1999-12-09
SV1999000069A (es) 2000-04-11
AR019851A1 (es) 2002-03-20
AU4227799A (en) 1999-12-20
CO5060478A1 (es) 2001-07-30
EP0962466A1 (en) 1999-12-08

Similar Documents

Publication Publication Date Title
DE69834824D1 (de) Nukleinsäure, welche einen von lektin abstammenden faktor zur präservierung von progenitorzellen kodiert
CO4600683A1 (es) Bikunina humana
DK0917571T3 (da) Hidtil ukendt agoutirelateret gen
DE69932599D1 (de) Künstliche chromosomen, die die genetische information für die bildung von rekombinantem virus enthalten
AR024335A1 (es) Hialuronidasa de hirudinaria manillensis, aislamiento, purificacion y metodo recombinante de produccion
EP2261249A3 (en) KDR peptides and vaccines comprising the same
EA200101037A1 (ru) Соединения и способы для лечения и диагностики рака легкого
RU2009128647A (ru) Варианты дезинтегрина и их фармацевтическое применение
AR054526A1 (es) Metodo para tartar pacientes con una vacuna de glicoproteina mucinosa (muc-1)
HK1080895A1 (en) Hybrid hepatocyte growth factor gene having high expression efficiency of two heterotypes of hepatocyte growth factor
ATE478092T1 (de) Verbesserte sekretion von neublastin
NO20040222L (no) Peptider til fjerning eller destruksjon av celler
RU2015102027A (ru) Проникающие в клетку пептиды и способы идентификации проникающих в клетку пептидов
CA2461443A1 (en) Nucleic acid and amino acid sequences encoding high-level expressor factor viii polypeptides and methods of use
AR047574A1 (es) Genes del ciclo celular y metodos de uso relacionados
ATE309353T1 (de) Verfahren zur herstellung von rekombinanten peptiden
EA200300525A1 (ru) Гликозидирование индолкарбазола с применением межфазного катализа
PE20000539A1 (es) Secuencia del gen relacionado con angiopoyetina scarface 3
MXPA05005545A (es) Peptidos que se dirigen a celulas tomurales y endoteliales, composiciones y usos de los mismos.
HUP9904414A2 (hu) A neuritin neurogén
ATE494301T1 (de) Alpha-fetoprotein-peptide und ihre verwendung
AR047590A1 (es) Alteracion de la estructura de la raiz durante el desarrollo de la planta
FI20050753A (fi) Uudet peptidit
ATE363488T1 (de) Zusammensetzungen von stammzellfaktor (scf)- analogen und auf diese bezogene verfahren
DE69632963D1 (de) Mch3, eine apoptosis-protease, kodierende nukleinsäuren und methoden zur verwendung

Legal Events

Date Code Title Description
FC Refusal