PE11395A1 - PURIFIED FORM OF STREPTOGRAMINS, PROCEDURE FOR ITS PREPARATION AND PHARMACEUTICAL COMPOSITION THAT CONTAINS IT - Google Patents
PURIFIED FORM OF STREPTOGRAMINS, PROCEDURE FOR ITS PREPARATION AND PHARMACEUTICAL COMPOSITION THAT CONTAINS ITInfo
- Publication number
- PE11395A1 PE11395A1 PE1994246898A PE24689894A PE11395A1 PE 11395 A1 PE11395 A1 PE 11395A1 PE 1994246898 A PE1994246898 A PE 1994246898A PE 24689894 A PE24689894 A PE 24689894A PE 11395 A1 PE11395 A1 PE 11395A1
- Authority
- PE
- Peru
- Prior art keywords
- purified form
- streptogramins
- procedure
- preparation
- pharmaceutical composition
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06139—Dipeptides with the first amino acid being heterocyclic
- C07K5/06182—Dipeptides with the first amino acid being heterocyclic and Pristinamycin II; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06139—Dipeptides with the first amino acid being heterocyclic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Immunology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Peptides Or Proteins (AREA)
Abstract
SE REFIERE A UNA FORMA PURIFICADA QUE COMPRENDE UNA ASOCIACION DE: 1) UNA ESTREPTOGRAMINA DEL GRUPO B DE FORMULA I DONDE A1 PUEDE SER: A) ENLACE1-CO-PIPERIDINA(-R1)(=O)-CO-CH(-CH2-C6H4Y)-ENLACE2 o B) ENLACE1-CO-CH(-CH2-COOH)-NH-CO-CH(-CH2-C6H4(N(CH3)2))-ENLACE2; DONDE R` ES H, OH; Y ES H, METILAMINO, DIMETILAMINO; R ES ETILO, METILO; R1 y R2 SON HIDROGENOS o BIEN A1 PUEDE SER: C) ENLACE1-CO-CH(-CH3)-NH-CO-CH(-CH(CH3)-CH(CH3)2)-N(CH3)-CO-CH2-ENLACE2; DONDE R ES ISOBUTILO; R1 ES OH; R2 ES METILO; 2) UNO O VARIOS COMPONENTES MINORITARIOS DEL GRUPO A DE LAS ESTREPTOGRAMINAS DE FORMULA II, DONDE R'' ES H, ETILO; ESTA ASOCIACION SE ENCUENTRA EN FORMA DE UN COCRISTALIZADO, COPRECIPITADO O MEZCLA FISICA DE POLVOS CON MENOS DE 6% DE IMPUREZA Y PUEDE SER UTIL COMO ANTIBACTERIANOIT REFERS TO A PURIFIED FORM COMPRISING AN ASSOCIATION OF: 1) A STREPTOGRAMINE OF GROUP B OF FORMULA I WHERE A1 MAY BE: A) LINK1-CO-PIPERIDINE (-R1) (= O) -CO-CH (-CH2- C6H4Y) -LINK2 or B) LINK1-CO-CH (-CH2-COOH) -NH-CO-CH (-CH2-C6H4 (N (CH3) 2)) - LINK2; WHERE R` IS H, OH; Y IS H, METHYLAMINE, DIMETHYLAMINE; R IS ETHYL, METHYL; R1 and R2 ARE HYDROGEN OR ALSO A1 MAY BE: C) LINK1-CO-CH (-CH3) -NH-CO-CH (-CH (CH3) -CH (CH3) 2) -N (CH3) -CO-CH2 -LINK2; WHERE R IS ISOBUTYL; R1 IS OH; R2 IS METHYL; 2) ONE OR SEVERAL MINORITY COMPONENTS OF GROUP A OF THE FORMULA II STREPTOGRAMS, WHERE R '' IS H, ETHYL; THIS ASSOCIATION IS IN THE FORM OF A CO-CRYSTALLIZED, COPRECIPITATED OR PHYSICAL MIXTURE OF POWDERS WITH LESS THAN 6% OF IMPURITY AND MAY BE USEFUL AS AN ANTIBACTERIAL
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9301787A FR2701709B1 (en) | 1993-02-17 | 1993-02-17 | Purified form of streptogramins, its preparation and the pharmaceutical compositions containing it. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PE11395A1 true PE11395A1 (en) | 1995-07-14 |
Family
ID=34639851
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PE1994246898A PE11395A1 (en) | 1993-02-17 | 1994-07-18 | PURIFIED FORM OF STREPTOGRAMINS, PROCEDURE FOR ITS PREPARATION AND PHARMACEUTICAL COMPOSITION THAT CONTAINS IT |
Country Status (4)
| Country | Link |
|---|---|
| JP (1) | JP3718521B2 (en) |
| KR (1) | KR100333185B1 (en) |
| PE (1) | PE11395A1 (en) |
| UY (1) | UY23821A1 (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2016055278A (en) * | 2014-09-12 | 2016-04-21 | 竹上 敬三 | Dividing method of cocrystal |
-
1994
- 1994-02-15 KR KR1019940002667A patent/KR100333185B1/en not_active IP Right Cessation
- 1994-07-18 PE PE1994246898A patent/PE11395A1/en not_active Application Discontinuation
- 1994-08-29 UY UY23821A patent/UY23821A1/en unknown
-
2005
- 2005-02-03 JP JP2005028045A patent/JP3718521B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| JP3718521B2 (en) | 2005-11-24 |
| JP2005132849A (en) | 2005-05-26 |
| UY23821A1 (en) | 1995-02-17 |
| KR940019712A (en) | 1994-09-14 |
| KR100333185B1 (en) | 2002-08-21 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant, registration | ||
| FD | Application declared void or lapsed |