UY23821A1 - PURIFIED FORM OF STREPTOGRAMINS, PROCEDURE FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING IT. - Google Patents

PURIFIED FORM OF STREPTOGRAMINS, PROCEDURE FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING IT.

Info

Publication number
UY23821A1
UY23821A1 UY23821A UY23821A UY23821A1 UY 23821 A1 UY23821 A1 UY 23821A1 UY 23821 A UY23821 A UY 23821A UY 23821 A UY23821 A UY 23821A UY 23821 A1 UY23821 A1 UY 23821A1
Authority
UY
Uruguay
Prior art keywords
streptogramins
purified form
group
procedure
preparation
Prior art date
Application number
UY23821A
Other languages
Spanish (es)
Inventor
Bonnavaud Bertrand
Callet Alain
Lefevre Patrick
Anger Pascal
Original Assignee
Rhone Poulenc Rorer Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR9301787A external-priority patent/FR2701709B1/en
Application filed by Rhone Poulenc Rorer Sa filed Critical Rhone Poulenc Rorer Sa
Publication of UY23821A1 publication Critical patent/UY23821A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06139—Dipeptides with the first amino acid being heterocyclic
    • C07K5/06182—Dipeptides with the first amino acid being heterocyclic and Pristinamycin II; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06139—Dipeptides with the first amino acid being heterocyclic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Una forma purificada de estreptograminas, caracterizadas en que esta constituida de la asociación de uno o varios componentes del grupo B de las estreptograminas, de fórmula l, en la cual A1 es un radical de fórmula ll; R puede representar metilo, y R1 y R2 un átomo de H. Una composición farmacéutica, caracterizada por que una forma purificada de estreptograminas, en el estado puro o en la presencia de cualquier diluyente o adyuvante compatible y farmacéuticamente aceptable. Un procedimiento de purificación de un componente minoritario del grupo A de las estreptograminas, caracterizado en que se prepara un compuesto cocristalizado de este componente con uno o varios componentes del grupo B de las estreptograminas, después se elimina el (los) componente(s) del grupo B, mediante el tratamiento en medio ácido.A purified form of streptogramins, characterized in that it consists of the association of one or more components of group B of streptogramins, of formula I, in which A1 is a radical of formula II; R can represent methyl, and R1 and R2 an H atom. A pharmaceutical composition, characterized in that it is a purified form of streptogramins, in the pure state or in the presence of any compatible and pharmaceutically acceptable diluent or adjuvant. A purification procedure of a minor component of group A of streptogramins, characterized in that a co-crystallized compound of this component is prepared with one or more components of group B of streptogramins, then the component (s) of the group B, by treatment in an acid medium.

UY23821A 1993-02-17 1994-08-29 PURIFIED FORM OF STREPTOGRAMINS, PROCEDURE FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING IT. UY23821A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9301787A FR2701709B1 (en) 1993-02-17 1993-02-17 Purified form of streptogramins, its preparation and the pharmaceutical compositions containing it.

Publications (1)

Publication Number Publication Date
UY23821A1 true UY23821A1 (en) 1995-02-17

Family

ID=34639851

Family Applications (1)

Application Number Title Priority Date Filing Date
UY23821A UY23821A1 (en) 1993-02-17 1994-08-29 PURIFIED FORM OF STREPTOGRAMINS, PROCEDURE FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING IT.

Country Status (4)

Country Link
JP (1) JP3718521B2 (en)
KR (1) KR100333185B1 (en)
PE (1) PE11395A1 (en)
UY (1) UY23821A1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2016055278A (en) * 2014-09-12 2016-04-21 竹上　敬三 Dividing method of cocrystal

Also Published As

Publication number Publication date
JP3718521B2 (en) 2005-11-24
JP2005132849A (en) 2005-05-26
KR940019712A (en) 1994-09-14
KR100333185B1 (en) 2002-08-21
PE11395A1 (en) 1995-07-14

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