PE105899A1 - Progestagenos cristalinos - Google Patents
Progestagenos cristalinosInfo
- Publication number
- PE105899A1 PE105899A1 PE1998000708A PE00070898A PE105899A1 PE 105899 A1 PE105899 A1 PE 105899A1 PE 1998000708 A PE1998000708 A PE 1998000708A PE 00070898 A PE00070898 A PE 00070898A PE 105899 A1 PE105899 A1 PE 105899A1
- Authority
- PE
- Peru
- Prior art keywords
- refers
- crystal form
- progestagens
- crystalline
- entalpia
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0003—Androstane derivatives
- C07J1/0033—Androstane derivatives substituted in position 17 alfa and 17 beta
- C07J1/004—Androstane derivatives substituted in position 17 alfa and 17 beta the substituent in position 17 alfa being an unsaturated hydrocarbon group
- C07J1/0048—Alkynyl derivatives
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
SE REFIERE A UNA NUEVA FORMA CRISTALINA DE (17O)-17-HIDROXI-11-METILEN-19-NORPREGNA-4,15-DIENO-20-IN-3-ONA, CARACTERIZADA POR SU a)ENTALPIA (DELTA H) DE ALREDEDOR DE 70 mJ/mg, MEDIDA EN LA CURVA DE CALORIMETRIA DIFERENCIAL; b)PUNTO DE FUSION DE 160�C, c)ESPECTRO DE RESONANCIA MAGNETICA NUCLEAR 13C, d)PATRON DE DIFRACCION DE RAYOS X. TAMBIEN SE REFIERE A UN PROCEDIMIENTO PARA LA PREPARACION QUE COMPRENDE SINTETIZAR LA FORMA CRISTALINA Y LUEGO CRISTALIZAR A PARTIR DE UNA MEZCLA DE SOLVENTES COMO ACETATO DE ETILO Y n-HEPTANO. TAMBIEN SE REFIERE A UNA COMPOSICION DE LIBERACION CONTINUA Y CONTROLADA. LA FORMA CRISTALINA PUEDE SER UTIL COMO ANTICONCEPTIVO ORAL, EN LA TERAPIA DE SUSTITUCION DE HORMONAS
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP97202472 | 1997-08-11 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PE105899A1 true PE105899A1 (es) | 1999-10-30 |
Family
ID=8228632
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PE1998000708A PE105899A1 (es) | 1997-08-11 | 1998-08-07 | Progestagenos cristalinos |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US20020010166A1 (es) |
| JP (1) | JPH11116595A (es) |
| KR (1) | KR19990023484A (es) |
| CN (1) | CN1208043A (es) |
| AR (1) | AR015146A1 (es) |
| AU (1) | AU740229B2 (es) |
| BR (1) | BR9803129A (es) |
| CA (1) | CA2244619A1 (es) |
| CO (1) | CO4960661A1 (es) |
| CZ (1) | CZ252798A3 (es) |
| HU (1) | HUP9801850A3 (es) |
| ID (1) | ID21262A (es) |
| IL (1) | IL125503A0 (es) |
| NO (1) | NO983650L (es) |
| NZ (1) | NZ331197A (es) |
| PE (1) | PE105899A1 (es) |
| PL (1) | PL327915A1 (es) |
| SG (1) | SG66491A1 (es) |
| TR (1) | TR199801520A1 (es) |
| ZA (1) | ZA986943B (es) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2000050041A1 (en) * | 1999-02-24 | 2000-08-31 | Akzo Nobel N.V. | Pharmaceutical compositions containing a crystalline form of the progestagen-(17alpha)-17-hydroxy-11-methylene-19-nor-pregna-4,15-dien-20-yn-3-one (org 30659) and lactose |
-
1998
- 1998-07-24 IL IL12550398A patent/IL125503A0/xx unknown
- 1998-07-31 NZ NZ331197A patent/NZ331197A/en unknown
- 1998-07-31 CA CA002244619A patent/CA2244619A1/en not_active Abandoned
- 1998-08-03 SG SG1998002740A patent/SG66491A1/en unknown
- 1998-08-03 ZA ZA986943A patent/ZA986943B/xx unknown
- 1998-08-04 US US09/128,434 patent/US20020010166A1/en not_active Abandoned
- 1998-08-07 ID IDP981110A patent/ID21262A/id unknown
- 1998-08-07 JP JP10223974A patent/JPH11116595A/ja active Pending
- 1998-08-07 PE PE1998000708A patent/PE105899A1/es not_active Application Discontinuation
- 1998-08-10 HU HU9801850A patent/HUP9801850A3/hu unknown
- 1998-08-10 CN CN98116281A patent/CN1208043A/zh active Pending
- 1998-08-10 AR ARP980103937A patent/AR015146A1/es unknown
- 1998-08-10 AU AU78966/98A patent/AU740229B2/en not_active Ceased
- 1998-08-10 KR KR1019980032366A patent/KR19990023484A/ko not_active Application Discontinuation
- 1998-08-10 PL PL98327915A patent/PL327915A1/xx unknown
- 1998-08-10 BR BR9803129-5A patent/BR9803129A/pt not_active IP Right Cessation
- 1998-08-10 NO NO983650A patent/NO983650L/no not_active Application Discontinuation
- 1998-08-11 CZ CZ982527A patent/CZ252798A3/cs unknown
- 1998-08-11 CO CO98045877A patent/CO4960661A1/es unknown
- 1998-08-11 TR TR1998/01520A patent/TR199801520A1/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| SG66491A1 (en) | 1999-07-20 |
| HU9801850D0 (en) | 1998-10-28 |
| CN1208043A (zh) | 1999-02-17 |
| NZ331197A (en) | 1998-11-25 |
| AR015146A1 (es) | 2001-04-18 |
| CA2244619A1 (en) | 1999-02-11 |
| PL327915A1 (en) | 1999-02-15 |
| US20020010166A1 (en) | 2002-01-24 |
| NO983650D0 (no) | 1998-08-10 |
| IL125503A0 (en) | 1999-03-12 |
| CO4960661A1 (es) | 2000-09-25 |
| JPH11116595A (ja) | 1999-04-27 |
| AU740229B2 (en) | 2001-11-01 |
| BR9803129A (pt) | 2000-05-02 |
| ID21262A (id) | 1999-05-12 |
| NO983650L (no) | 1999-02-12 |
| ZA986943B (en) | 1999-02-04 |
| CZ252798A3 (cs) | 1999-06-16 |
| AU7896698A (en) | 1999-02-18 |
| HUP9801850A3 (en) | 2000-01-28 |
| KR19990023484A (ko) | 1999-03-25 |
| HUP9801850A2 (hu) | 1999-04-28 |
| TR199801520A1 (xx) | 1999-02-22 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD | Application declared void or lapsed |