PA8802201A1 - Compuestos de bencensulfonalida apropiados para tratar trastornos que responden a la modulacion del receptor de serotonina 5-ht6 - Google Patents

Compuestos de bencensulfonalida apropiados para tratar trastornos que responden a la modulacion del receptor de serotonina 5-ht6

Info

Publication number
PA8802201A1
PA8802201A1 PA20088802201A PA8802201A PA8802201A1 PA 8802201 A1 PA8802201 A1 PA 8802201A1 PA 20088802201 A PA20088802201 A PA 20088802201A PA 8802201 A PA8802201 A PA 8802201A PA 8802201 A1 PA8802201 A1 PA 8802201A1
Authority
PA
Panama
Prior art keywords
hydrogen
serotonine
receptor
respond
modulation
Prior art date
Application number
PA20088802201A
Other languages
English (en)
Inventor
Colm Turner Sean
Haupt Andreas
Lange Udo
Drescher Karla
Wicke Karsten
Unger Liliane
Mezler Mario
Wernet Wolfgang
Mayrer Matthias
Martin Braje Wilfried
Jongen-Relo Ana
Bespalov Anton
Zhang Min
Original Assignee
Abbott Gmbh & Co Kg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40340548&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PA8802201(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Abbott Gmbh & Co Kg filed Critical Abbott Gmbh & Co Kg
Publication of PA8802201A1 publication Critical patent/PA8802201A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Addiction (AREA)
  • Diabetes (AREA)
  • Child & Adolescent Psychology (AREA)
  • Psychology (AREA)
  • Anesthesiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Nutrition Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)

Abstract

NUEVOS COMPUESTOS DE BENCENSULFONANILIDA DE LAS FÓRMULAS I Y I' SALES DE ADICIÓN ÁCIDA TOLERADA PARA APLICACIONES FISIOLÓGICAS Y SUS N-ÓXIDOS. LOS COMOUESTOS POSEEN PROPIEDADES TERAPÉUTICAS VALIOSAS Y SON PARTICULARMENTE ADECUADOS PARA EL TRATAMIENTO DE ENFERMEDADES QUE RESPONDEN A LA MODULACIÓN DEL RECEPTOR DE SEROTONINA 5-HT6. EN DONDE R1 ES HIDRÓGENO O METILO R2 ES HIDRÓGENO O METILO R3 HIDRÓGENO, FLÚOR C1-C2 ALCOXI O C1-C2 ALCOXI FLUORADO; R4 ES HIDRÓGENO, C1-C4 ALQUILO O C1-C4 ALQUILO FLUORADO; R5 ES HIDRÓGENO, FLÚOR, C1-C2 ALQUILO, C1-C2 ALQUILO FLUORADO, C1-C2 ALCOXI O C1-C2 ALCOXI FLUORADO; Y R6 ES HIDRÓGENO, FLUÓR O CLORO.
PA20088802201A 2007-11-02 2008-10-29 Compuestos de bencensulfonalida apropiados para tratar trastornos que responden a la modulacion del receptor de serotonina 5-ht6 PA8802201A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US165607P 2007-11-02 2007-11-02

Publications (1)

Publication Number Publication Date
PA8802201A1 true PA8802201A1 (es) 2009-06-23

Family

ID=40340548

Family Applications (1)

Application Number Title Priority Date Filing Date
PA20088802201A PA8802201A1 (es) 2007-11-02 2008-10-29 Compuestos de bencensulfonalida apropiados para tratar trastornos que responden a la modulacion del receptor de serotonina 5-ht6

Country Status (22)

Country Link
US (2) US7790727B2 (es)
EP (1) EP2217583B1 (es)
JP (1) JP2011502973A (es)
KR (1) KR20100100849A (es)
CN (1) CN101918384A (es)
AR (1) AR069151A1 (es)
AT (1) ATE535517T1 (es)
AU (1) AU2008320821A1 (es)
BR (1) BRPI0819233A2 (es)
CA (1) CA2704529A1 (es)
CL (1) CL2008003232A1 (es)
ES (1) ES2378596T3 (es)
IL (1) IL205469A0 (es)
MX (1) MX2010004832A (es)
NZ (1) NZ585087A (es)
PA (1) PA8802201A1 (es)
PE (1) PE20091016A1 (es)
RU (1) RU2010122300A (es)
TW (1) TW200927117A (es)
UY (1) UY31447A1 (es)
WO (1) WO2009056632A1 (es)
ZA (1) ZA201003594B (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PA8802201A1 (es) * 2007-11-02 2009-06-23 Abbott Gmbh & Co Kg Compuestos de bencensulfonalida apropiados para tratar trastornos que responden a la modulacion del receptor de serotonina 5-ht6
US8183237B2 (en) * 2009-04-30 2012-05-22 Abbott Laboratories Benzenesulfonanilide compounds suitable for treating disorders that respond to modulation of the serotonin 5-HT6 receptor
CN105085436B (zh) 2014-04-19 2019-08-16 广东东阳光药业有限公司 磺酰胺类衍生物及其在药物上的应用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DZ2376A1 (fr) * 1996-12-19 2002-12-28 Smithkline Beecham Plc Dérivés de sulfonamides nouveaux procédé pour leurpréparation et compositions pharmaceutiques les c ontenant.
GB9818916D0 (en) * 1998-08-28 1998-10-21 Smithkline Beecham Plc Use
GB9818914D0 (en) * 1998-08-28 1998-10-21 Smithkline Beecham Plc Use
SE0002739D0 (sv) * 2000-07-21 2000-07-21 Pharmacia & Upjohn Ab New use
BRPI0513713A (pt) * 2004-07-28 2008-05-13 Glaxo Group Ltd derivados de piperazina úteis para o tratamento de distúrbios gastrointestinais
PA8802201A1 (es) * 2007-11-02 2009-06-23 Abbott Gmbh & Co Kg Compuestos de bencensulfonalida apropiados para tratar trastornos que responden a la modulacion del receptor de serotonina 5-ht6

Also Published As

Publication number Publication date
ZA201003594B (en) 2011-02-23
US20110086863A1 (en) 2011-04-14
PE20091016A1 (es) 2009-08-15
IL205469A0 (en) 2010-12-30
RU2010122300A (ru) 2011-12-10
MX2010004832A (es) 2010-10-20
AR069151A1 (es) 2009-12-30
ES2378596T3 (es) 2012-04-16
CN101918384A (zh) 2010-12-15
US7790727B2 (en) 2010-09-07
BRPI0819233A2 (pt) 2017-05-02
UY31447A1 (es) 2009-05-29
EP2217583B1 (en) 2011-11-30
ATE535517T1 (de) 2011-12-15
US20090131452A1 (en) 2009-05-21
CL2008003232A1 (es) 2009-11-27
AU2008320821A1 (en) 2009-05-07
EP2217583A1 (en) 2010-08-18
JP2011502973A (ja) 2011-01-27
KR20100100849A (ko) 2010-09-15
CA2704529A1 (en) 2009-05-07
NZ585087A (en) 2012-06-29
WO2009056632A1 (en) 2009-05-07
TW200927117A (en) 2009-07-01

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