PA8781801A1 - Derivados heteroarilo antidepresivos de benzodioxanos heterociclo-fusionados - Google Patents

Derivados heteroarilo antidepresivos de benzodioxanos heterociclo-fusionados

Info

Publication number
PA8781801A1
PA8781801A1 PA20088781801A PA8781801A PA8781801A1 PA 8781801 A1 PA8781801 A1 PA 8781801A1 PA 20088781801 A PA20088781801 A PA 20088781801A PA 8781801 A PA8781801 A PA 8781801A PA 8781801 A1 PA8781801 A1 PA 8781801A1
Authority
PA
Panama
Prior art keywords
disorder
fusionados
benzodioxanos
heterociclo
heteroarilo
Prior art date
Application number
PA20088781801A
Other languages
English (en)
Inventor
Li Yanfang
A Failli Amadeo
Evrard Deborah
T Hatzenbuhler Nicole
Mogish Juliann
S Gunawan Iwan
Nikitenko Antonina
Zhou Ping
Original Assignee
Wyeth Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth Corp filed Critical Wyeth Corp
Publication of PA8781801A1 publication Critical patent/PA8781801A1/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/12Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/32Alcohol-abuse
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/36Opioid-abuse

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Neurology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Addiction (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

LA INVENCIÓN PROPORCIONA COMPUESTOS DE FÓRMULA: QUE SON ÚTILES PARA EL TRATAMIENTO DE LA DEPRESIÓN(QUE INCLUYE,AUNQUE NO A MODO DE LIMITACIÓN,TRASTORNO DEPRESIVO GRAVE,DEPRESIÓN EN LA NIÑEZ Y DISTIMIA),ANSIEDAD,TRASTORNO DE PÁNICO,TRASTORNO DE ESTRÉS POST-TRAUMÀTICO,TRASTORNO DISFÓRICO PREMESTRUAL(TAMBIÉN CONOCIDO COMO SÍNDROME PRE-MESTRUAL),TRASTORNO DE DÉFICIT DE ATENCIÓN(CON Y SIN HIPERACTIVIDAD),TRASTORNO OBSESIVO-COMPULSIVO,TRASTORNO DE ANSIEDAD SOCIAL,TRASTORNO DE ANSIEDAD GENERALIZADA, OBESIDAD,TRASTORNOS ALIMENTICIOS TALES COMO ANOREXIA, NERVIOSA,BULIMIA NERVIOSA,RUBEFACCIÓN VASOMOTORA, ADICCIÓN A LA COCAÍNA Y AL ALCOHOL, DISFUCIÓN SEXUAL Y ENFERMEDADES RELACIONADAS.
PA20088781801A 2007-05-30 2008-05-29 Derivados heteroarilo antidepresivos de benzodioxanos heterociclo-fusionados PA8781801A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US94076507P 2007-05-30 2007-05-30

Publications (1)

Publication Number Publication Date
PA8781801A1 true PA8781801A1 (es) 2009-01-23

Family

ID=39720304

Family Applications (1)

Application Number Title Priority Date Filing Date
PA20088781801A PA8781801A1 (es) 2007-05-30 2008-05-29 Derivados heteroarilo antidepresivos de benzodioxanos heterociclo-fusionados

Country Status (7)

Country Link
US (1) US20090042874A1 (es)
AR (1) AR066760A1 (es)
CL (1) CL2008001563A1 (es)
PA (1) PA8781801A1 (es)
PE (1) PE20090759A1 (es)
TW (1) TW200904446A (es)
WO (1) WO2008150848A1 (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2766088C (en) 2009-06-25 2017-06-13 Alkermes, Inc. Heterocyclic compounds for the treatment of neurological and psychological disorders
ES2834973T3 (es) 2010-05-04 2021-06-21 Alkermes Pharma Ireland Ltd Procedimiento de síntesis de compuestos de lactama oxidada
EP2585066B1 (en) 2010-06-24 2018-09-26 Alkermes Pharma Ireland Limited Prodrugs of nh-acidic compounds: ester, carbonate, carbamate and phosphonate derivatives
CN104356063A (zh) * 2014-10-16 2015-02-18 华东师范大学 7-羟基-3,4-二氢-2-(1h)喹诺酮的制备方法
EP3233799B1 (en) 2014-12-19 2021-05-19 The Broad Institute, Inc. Dopamine d2 receptor ligands
WO2016100940A1 (en) 2014-12-19 2016-06-23 The Broad Institute, Inc. Dopamine d2 receptor ligands
CN111909170B (zh) * 2020-09-11 2022-08-12 吉林奥来德光电材料股份有限公司 一种有机电致发光化合物、其制备方法以及包含该有机电致发光化合物的有机电致发光器件

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6319241B1 (en) * 1998-04-30 2001-11-20 Medtronic, Inc. Techniques for positioning therapy delivery elements within a spinal cord or a brain
US6421566B1 (en) * 1998-04-30 2002-07-16 Medtronic, Inc. Selective dorsal column stimulation in SCS, using conditioning pulses
US6941171B2 (en) * 1998-07-06 2005-09-06 Advanced Bionics Corporation Implantable stimulator methods for treatment of incontinence and pain
US6407092B1 (en) * 1999-04-23 2002-06-18 Pharmacia & Upjohn Company Tetracyclic azepinoindole compounds
US6516227B1 (en) * 1999-07-27 2003-02-04 Advanced Bionics Corporation Rechargeable spinal cord stimulator system
FR2801885B1 (fr) * 1999-12-06 2002-01-11 Adir Nouveaux derives (dihydro)benzoxaziniques et (dihydro) benzothiaziniques substitues, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
US6885888B2 (en) * 2000-01-20 2005-04-26 The Cleveland Clinic Foundation Electrical stimulation of the sympathetic nerve chain
US6697676B2 (en) * 2000-12-21 2004-02-24 Medtronic, Inc. Medical electrical lead having an expandable electrode assembly
US6735472B2 (en) * 2001-01-26 2004-05-11 Pacesetter, Inc. Method of defibrillating a heart with electrode configurations including a left ventricular defibrillation electrode
US6458802B1 (en) * 2001-03-14 2002-10-01 Wyeth Antidepressant azaheterocyclymethyl derivatives of 2,3-dihydro-1,4-dioxino [2,3-f]quinoline
WO2002088132A1 (en) * 2001-04-26 2002-11-07 Wyeth Azaheterocyclylmethyl derivatives of 2,3-dihydro-1,4-dioxino[2,3-f]quinoline as 5-ht1aantagonists
US6861427B2 (en) * 2001-04-26 2005-03-01 Wyeth Azabicyclylmethyl derivatives of 2,3-dihydro-1,4-dioxino[2,3-f]quinoline as 5-HT1A antagonists
BR0209901A (pt) * 2001-05-17 2004-07-13 Wyeth Corp Processos para a sìntese de derivados de 2,3-dihidro-1,4-dioxino-[2,3-f] quinolina
US7153849B2 (en) * 2002-09-12 2006-12-26 Wyeth Antidepressant arylpiperazine derivatives of hetrocycle-fused benzodioxans
US6939877B2 (en) * 2002-09-12 2005-09-06 Wyeth Antidepressant piperidine derivatives of heterocycle-fused benzodioxans
US6800637B2 (en) * 2002-09-12 2004-10-05 Wyeth Antidepressant indolealkyl derivatives of heterocycle-fused benzodioxan methylamines
US7135479B2 (en) * 2002-09-12 2006-11-14 Wyeth Antidepressant azaheterocyclylmethyl derivatives of heterocycle-fused benzodioxans
US6911445B2 (en) * 2002-09-12 2005-06-28 Wyeth Antidepressant cycloalkylamine derivatives of heterocycle-fused benzodioxans
GB0227240D0 (en) * 2002-11-21 2002-12-31 Glaxo Group Ltd Compounds
US7160888B2 (en) * 2003-08-22 2007-01-09 Warner Lambert Company Llc [1,8]naphthyridin-2-ones and related compounds for the treatment of schizophrenia
US7414052B2 (en) * 2004-03-30 2008-08-19 Wyeth Phenylaminopropanol derivatives and methods of their use
US20060062725A1 (en) * 2004-08-09 2006-03-23 Valliant John F Methods for preparing metal-carborane complexes for radioimaging and radiotherapy
WO2008042735A1 (en) * 2006-09-29 2008-04-10 Wyeth Tetrahydroquinoline, indoline, and related aniline derivatives of heterocycle-fused benzodioxan methylamines

Also Published As

Publication number Publication date
CL2008001563A1 (es) 2008-10-10
AR066760A1 (es) 2009-09-09
US20090042874A1 (en) 2009-02-12
PE20090759A1 (es) 2009-07-20
TW200904446A (en) 2009-02-01
WO2008150848A1 (en) 2008-12-11

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