PA8781801A1 - Derivados heteroarilo antidepresivos de benzodioxanos heterociclo-fusionados - Google Patents
Derivados heteroarilo antidepresivos de benzodioxanos heterociclo-fusionadosInfo
- Publication number
- PA8781801A1 PA8781801A1 PA20088781801A PA8781801A PA8781801A1 PA 8781801 A1 PA8781801 A1 PA 8781801A1 PA 20088781801 A PA20088781801 A PA 20088781801A PA 8781801 A PA8781801 A PA 8781801A PA 8781801 A1 PA8781801 A1 PA 8781801A1
- Authority
- PA
- Panama
- Prior art keywords
- disorder
- fusionados
- benzodioxanos
- heterociclo
- heteroarilo
- Prior art date
Links
- 230000001430 anti-depressive effect Effects 0.000 title 1
- 208000020401 Depressive disease Diseases 0.000 abstract 2
- 206010029216 Nervousness Diseases 0.000 abstract 2
- ZPUCINDJVBIVPJ-LJISPDSOSA-N cocaine Chemical compound O([C@H]1C[C@@H]2CC[C@@H](N2C)[C@H]1C(=O)OC)C(=O)C1=CC=CC=C1 ZPUCINDJVBIVPJ-LJISPDSOSA-N 0.000 abstract 2
- 208000019901 Anxiety disease Diseases 0.000 abstract 1
- 208000006096 Attention Deficit Disorder with Hyperactivity Diseases 0.000 abstract 1
- 208000036864 Attention deficit/hyperactivity disease Diseases 0.000 abstract 1
- 208000032841 Bulimia Diseases 0.000 abstract 1
- 206010006550 Bulimia nervosa Diseases 0.000 abstract 1
- 206010012335 Dependence Diseases 0.000 abstract 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 1
- 208000021384 Obsessive-Compulsive disease Diseases 0.000 abstract 1
- 201000001880 Sexual dysfunction Diseases 0.000 abstract 1
- 230000036506 anxiety Effects 0.000 abstract 1
- 208000015802 attention deficit-hyperactivity disease Diseases 0.000 abstract 1
- 229960003920 cocaine Drugs 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 230000001544 dysphoric effect Effects 0.000 abstract 1
- 208000013403 hyperactivity Diseases 0.000 abstract 1
- 208000035231 inattentive type attention deficit hyperactivity disease Diseases 0.000 abstract 1
- 208000019906 panic disease Diseases 0.000 abstract 1
- 231100000872 sexual dysfunction Toxicity 0.000 abstract 1
- 208000011580 syndromic disease Diseases 0.000 abstract 1
- 238000011282 treatment Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/32—Alcohol-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/36—Opioid-abuse
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Neurology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Addiction (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
LA INVENCIÓN PROPORCIONA COMPUESTOS DE FÓRMULA: QUE SON ÚTILES PARA EL TRATAMIENTO DE LA DEPRESIÓN(QUE INCLUYE,AUNQUE NO A MODO DE LIMITACIÓN,TRASTORNO DEPRESIVO GRAVE,DEPRESIÓN EN LA NIÑEZ Y DISTIMIA),ANSIEDAD,TRASTORNO DE PÁNICO,TRASTORNO DE ESTRÉS POST-TRAUMÀTICO,TRASTORNO DISFÓRICO PREMESTRUAL(TAMBIÉN CONOCIDO COMO SÍNDROME PRE-MESTRUAL),TRASTORNO DE DÉFICIT DE ATENCIÓN(CON Y SIN HIPERACTIVIDAD),TRASTORNO OBSESIVO-COMPULSIVO,TRASTORNO DE ANSIEDAD SOCIAL,TRASTORNO DE ANSIEDAD GENERALIZADA, OBESIDAD,TRASTORNOS ALIMENTICIOS TALES COMO ANOREXIA, NERVIOSA,BULIMIA NERVIOSA,RUBEFACCIÓN VASOMOTORA, ADICCIÓN A LA COCAÍNA Y AL ALCOHOL, DISFUCIÓN SEXUAL Y ENFERMEDADES RELACIONADAS.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US94076507P | 2007-05-30 | 2007-05-30 |
Publications (1)
Publication Number | Publication Date |
---|---|
PA8781801A1 true PA8781801A1 (es) | 2009-01-23 |
Family
ID=39720304
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PA20088781801A PA8781801A1 (es) | 2007-05-30 | 2008-05-29 | Derivados heteroarilo antidepresivos de benzodioxanos heterociclo-fusionados |
Country Status (7)
Country | Link |
---|---|
US (1) | US20090042874A1 (es) |
AR (1) | AR066760A1 (es) |
CL (1) | CL2008001563A1 (es) |
PA (1) | PA8781801A1 (es) |
PE (1) | PE20090759A1 (es) |
TW (1) | TW200904446A (es) |
WO (1) | WO2008150848A1 (es) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2766088C (en) | 2009-06-25 | 2017-06-13 | Alkermes, Inc. | Heterocyclic compounds for the treatment of neurological and psychological disorders |
ES2834973T3 (es) | 2010-05-04 | 2021-06-21 | Alkermes Pharma Ireland Ltd | Procedimiento de síntesis de compuestos de lactama oxidada |
EP2585066B1 (en) | 2010-06-24 | 2018-09-26 | Alkermes Pharma Ireland Limited | Prodrugs of nh-acidic compounds: ester, carbonate, carbamate and phosphonate derivatives |
CN104356063A (zh) * | 2014-10-16 | 2015-02-18 | 华东师范大学 | 7-羟基-3,4-二氢-2-(1h)喹诺酮的制备方法 |
EP3233799B1 (en) | 2014-12-19 | 2021-05-19 | The Broad Institute, Inc. | Dopamine d2 receptor ligands |
WO2016100940A1 (en) | 2014-12-19 | 2016-06-23 | The Broad Institute, Inc. | Dopamine d2 receptor ligands |
CN111909170B (zh) * | 2020-09-11 | 2022-08-12 | 吉林奥来德光电材料股份有限公司 | 一种有机电致发光化合物、其制备方法以及包含该有机电致发光化合物的有机电致发光器件 |
Family Cites Families (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6319241B1 (en) * | 1998-04-30 | 2001-11-20 | Medtronic, Inc. | Techniques for positioning therapy delivery elements within a spinal cord or a brain |
US6421566B1 (en) * | 1998-04-30 | 2002-07-16 | Medtronic, Inc. | Selective dorsal column stimulation in SCS, using conditioning pulses |
US6941171B2 (en) * | 1998-07-06 | 2005-09-06 | Advanced Bionics Corporation | Implantable stimulator methods for treatment of incontinence and pain |
US6407092B1 (en) * | 1999-04-23 | 2002-06-18 | Pharmacia & Upjohn Company | Tetracyclic azepinoindole compounds |
US6516227B1 (en) * | 1999-07-27 | 2003-02-04 | Advanced Bionics Corporation | Rechargeable spinal cord stimulator system |
FR2801885B1 (fr) * | 1999-12-06 | 2002-01-11 | Adir | Nouveaux derives (dihydro)benzoxaziniques et (dihydro) benzothiaziniques substitues, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
US6885888B2 (en) * | 2000-01-20 | 2005-04-26 | The Cleveland Clinic Foundation | Electrical stimulation of the sympathetic nerve chain |
US6697676B2 (en) * | 2000-12-21 | 2004-02-24 | Medtronic, Inc. | Medical electrical lead having an expandable electrode assembly |
US6735472B2 (en) * | 2001-01-26 | 2004-05-11 | Pacesetter, Inc. | Method of defibrillating a heart with electrode configurations including a left ventricular defibrillation electrode |
US6458802B1 (en) * | 2001-03-14 | 2002-10-01 | Wyeth | Antidepressant azaheterocyclymethyl derivatives of 2,3-dihydro-1,4-dioxino [2,3-f]quinoline |
WO2002088132A1 (en) * | 2001-04-26 | 2002-11-07 | Wyeth | Azaheterocyclylmethyl derivatives of 2,3-dihydro-1,4-dioxino[2,3-f]quinoline as 5-ht1aantagonists |
US6861427B2 (en) * | 2001-04-26 | 2005-03-01 | Wyeth | Azabicyclylmethyl derivatives of 2,3-dihydro-1,4-dioxino[2,3-f]quinoline as 5-HT1A antagonists |
BR0209901A (pt) * | 2001-05-17 | 2004-07-13 | Wyeth Corp | Processos para a sìntese de derivados de 2,3-dihidro-1,4-dioxino-[2,3-f] quinolina |
US7153849B2 (en) * | 2002-09-12 | 2006-12-26 | Wyeth | Antidepressant arylpiperazine derivatives of hetrocycle-fused benzodioxans |
US6939877B2 (en) * | 2002-09-12 | 2005-09-06 | Wyeth | Antidepressant piperidine derivatives of heterocycle-fused benzodioxans |
US6800637B2 (en) * | 2002-09-12 | 2004-10-05 | Wyeth | Antidepressant indolealkyl derivatives of heterocycle-fused benzodioxan methylamines |
US7135479B2 (en) * | 2002-09-12 | 2006-11-14 | Wyeth | Antidepressant azaheterocyclylmethyl derivatives of heterocycle-fused benzodioxans |
US6911445B2 (en) * | 2002-09-12 | 2005-06-28 | Wyeth | Antidepressant cycloalkylamine derivatives of heterocycle-fused benzodioxans |
GB0227240D0 (en) * | 2002-11-21 | 2002-12-31 | Glaxo Group Ltd | Compounds |
US7160888B2 (en) * | 2003-08-22 | 2007-01-09 | Warner Lambert Company Llc | [1,8]naphthyridin-2-ones and related compounds for the treatment of schizophrenia |
US7414052B2 (en) * | 2004-03-30 | 2008-08-19 | Wyeth | Phenylaminopropanol derivatives and methods of their use |
US20060062725A1 (en) * | 2004-08-09 | 2006-03-23 | Valliant John F | Methods for preparing metal-carborane complexes for radioimaging and radiotherapy |
WO2008042735A1 (en) * | 2006-09-29 | 2008-04-10 | Wyeth | Tetrahydroquinoline, indoline, and related aniline derivatives of heterocycle-fused benzodioxan methylamines |
-
2008
- 2008-05-29 AR ARP080102259A patent/AR066760A1/es unknown
- 2008-05-29 PE PE2008000918A patent/PE20090759A1/es not_active Application Discontinuation
- 2008-05-29 PA PA20088781801A patent/PA8781801A1/es unknown
- 2008-05-29 TW TW097119860A patent/TW200904446A/zh unknown
- 2008-05-29 CL CL200801563A patent/CL2008001563A1/es unknown
- 2008-05-29 US US12/128,930 patent/US20090042874A1/en not_active Abandoned
- 2008-05-29 WO PCT/US2008/065058 patent/WO2008150848A1/en active Application Filing
Also Published As
Publication number | Publication date |
---|---|
CL2008001563A1 (es) | 2008-10-10 |
AR066760A1 (es) | 2009-09-09 |
US20090042874A1 (en) | 2009-02-12 |
PE20090759A1 (es) | 2009-07-20 |
TW200904446A (en) | 2009-02-01 |
WO2008150848A1 (en) | 2008-12-11 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
PA8781801A1 (es) | Derivados heteroarilo antidepresivos de benzodioxanos heterociclo-fusionados | |
ECSP10010475A (es) | Derivados de azetidina y ciclobutano como inhibidores de jak | |
UY32629A (es) | Compuestos antivirales, composiciones y uso para la manufactura de un medicamento para el tratamiento de trastornos asociados con hepatitis c. | |
CO6511283A2 (es) | Primidinas sustituidas útiles en el tratamiento de enfermedades tales como cancer | |
PA8841901A1 (es) | Compuestos orgánicos | |
CO6511271A2 (es) | Compuestos de imidazopiridinil-aminopiridina sustituida | |
ECSP099823A (es) | Nuevos compuestos químicos | |
ECSP11011387A (es) | Anticuerpos biespecíficos anti-erbb-3/anti-c-met | |
UY32009A (es) | 5-alquinil-pirimidinas | |
CR20140071A (es) | Nuevos compuestos de 4-piperidinilo para uso como inhibidores de la tankirasa | |
UA111687C2 (uk) | Гетероароматичні сполуки як ліганди допаміну d1 | |
CL2011000137A1 (es) | Uso de compuestos derivados de 4,5-dihidro-oxazol-2-ilamina para tratar trastornos de ansiedad, trastornos bipolar, esquizofrenia, enfermedades neurológicas, epilepsias, migraña, trastornos metabólicos, trastornos cardiovasculares, entre otros; compuestos derivados de 4,5-dihidroxazol-2-ilamino; proceso de síntesis | |
CR20150171A (es) | Benzamidas | |
ECSP11011558A (es) | Nuevos compuestos químicos. | |
ECSP11010816A (es) | Nuevos Compuestos | |
PA8806801A1 (es) | Compuestos de amida como refuerzos de antivirales | |
PE20121556A1 (es) | 3,6-diazabiciclo[3.1.1]heptanos como ligandos de receptores nicotinicos neuronales de acetilcolina | |
ECSP109961A (es) | Derivados de indol-2-ona disustituidos en 3, su preparación y su aplicación en terapéutica | |
CL2011000865A1 (es) | Compuestos derivados de isoquinolinona; composicion farmaceutica que los comprende; y uso del compuesto para tratar enfermedades tales como psicosis, esquizofrenia, alzheimer entre otras. | |
CR20120592A (es) | Intermedios de agomelatina y métodos de preparación de estos | |
CU24420B1 (es) | Derivados de diheterociclo enlazado a cicloalquilo | |
CO6460762A2 (es) | 5-alquinil-piridinas | |
CL2017001588A1 (es) | Ácidos piridil-cicloalquil-carboxílicos sustituidos, composiciones que los contienen y usos de los mismos | |
SV2011003784A (es) | Nifurtimox para el tratamiento de enfermedades causadas por trichomonadida | |
CO6270354A2 (es) | Procedimiento mejorado para preparar 2-(fenil sustituido)-2-hidroxi-etil carbamatos |