PA8743601A1 - Proceso para preparar derivados de indonelinona fenilaminopropanol - Google Patents

Proceso para preparar derivados de indonelinona fenilaminopropanol

Info

Publication number
PA8743601A1
PA8743601A1 PA20078743601A PA8743601A PA8743601A1 PA 8743601 A1 PA8743601 A1 PA 8743601A1 PA 20078743601 A PA20078743601 A PA 20078743601A PA 8743601 A PA8743601 A PA 8743601A PA 8743601 A1 PA8743601 A1 PA 8743601A1
Authority
PA
Panama
Prior art keywords
phenylaminopropanol
indonelinone
prepare
processes
derivatives
Prior art date
Application number
PA20078743601A
Other languages
English (en)
Inventor
Ghosh Mousumi
Levent Mahmut
Ren Jianxin
Raveendranath Panolil
Ding Zhixian
Wai-Yin Chan Anita
A Nikitenko Antonia
R Potoski John
Zhou Maotang
Alimardanov Asaf
V Gontcharov Alexander
Original Assignee
Wyeth Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth Corp filed Critical Wyeth Corp
Publication of PA8743601A1 publication Critical patent/PA8743601A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/32—Oxygen atoms
    • C07D209/34—Oxygen atoms in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Psychiatry (AREA)
  • Urology & Nephrology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Indole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

SE DESCRIBEN PROCESOS PARA PREPARAR DERIVADOS DE INDOLINONA FENILAMINOPROPANOL, PARTICULARMENTE DERIVADOS QUIRALES DE INDOLINONA FENILAMINOPROPANOL DE LA FÓRMULA GENERAL I. LOS PROCESOS DESCRITOS PUEDEN USARSE PARA PREPARAR, INTER ALIA, 7-FLUORO-1-[(1S,2R)-1-(3-FLUOROFENIL)-2-HIDROXI-3-(METILAMINO)PROPIL]-3,3-DIMETIL-1,3-DIHIDRO-2H-INDOL-2-ONA Y 7-FLUORO-1-[(1S,2R)-1-(3,5-DIFLUOROFENIL)-2-HIDROXI-3-(METILAMINO)PROPIL]-3,3-DIMETIL-1,3-DIHIDRO-2H-INDOL-2-ONA. TAMBIÉN SE DESCRIBEN INTERMEDIOS DE LOS PROCESOS.
PA20078743601A 2006-08-24 2007-08-22 Proceso para preparar derivados de indonelinona fenilaminopropanol PA8743601A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US83997806P 2006-08-24 2006-08-24

Publications (1)

Publication Number Publication Date
PA8743601A1 true PA8743601A1 (es) 2009-02-09

Family

ID=38961789

Family Applications (1)

Application Number Title Priority Date Filing Date
PA20078743601A PA8743601A1 (es) 2006-08-24 2007-08-22 Proceso para preparar derivados de indonelinona fenilaminopropanol

Country Status (7)

Country Link
US (1) US20080146645A1 (es)
AR (1) AR062481A1 (es)
CL (1) CL2007002449A1 (es)
PA (1) PA8743601A1 (es)
PE (1) PE20080655A1 (es)
TW (1) TW200817382A (es)
WO (1) WO2008024492A2 (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2021000043A (es) 2018-07-03 2021-03-25 Univ Illinois Activadores de la respuesta a proteinas desplegadas.

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7414052B2 (en) * 2004-03-30 2008-08-19 Wyeth Phenylaminopropanol derivatives and methods of their use
US7517899B2 (en) * 2004-03-30 2009-04-14 Wyeth Phenylaminopropanol derivatives and methods of their use
US20070072897A1 (en) * 2005-09-29 2007-03-29 Wyeth Phenylaminopropanol derivatives and methods of their use

Also Published As

Publication number Publication date
TW200817382A (en) 2008-04-16
CL2007002449A1 (es) 2008-03-07
PE20080655A1 (es) 2008-07-14
WO2008024492A2 (en) 2008-02-28
AR062481A1 (es) 2008-11-12
WO2008024492A3 (en) 2008-05-15
US20080146645A1 (en) 2008-06-19

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