PA8636301A1 - Polimorfos cristalinos de (3s)-n-hidroxi-4-({4-[(4-hidroxi-2-butinil)oxi]fenil} sulfonil)-2,2-dimetil-3-tiomorfolina carboxamida - Google Patents

Polimorfos cristalinos de (3s)-n-hidroxi-4-({4-[(4-hidroxi-2-butinil)oxi]fenil} sulfonil)-2,2-dimetil-3-tiomorfolina carboxamida

Info

Publication number
PA8636301A1
PA8636301A1 PA20058636301A PA8636301A PA8636301A1 PA 8636301 A1 PA8636301 A1 PA 8636301A1 PA 20058636301 A PA20058636301 A PA 20058636301A PA 8636301 A PA8636301 A PA 8636301A PA 8636301 A1 PA8636301 A1 PA 8636301A1
Authority
PA
Panama
Prior art keywords
hidroxi
tiomorpholine
polymorphes
oxi
carboxamide
Prior art date
Application number
PA20058636301A
Other languages
English (en)
Inventor
Tong Wei
Lalitha Krishnan
Abdolsamad Tadayon
Peter John Larkin
Subodh S Deshmukh
Jean Marie Akin
Original Assignee
Wyeth Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth Corp filed Critical Wyeth Corp
Publication of PA8636301A1 publication Critical patent/PA8636301A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D279/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D279/10—1,4-Thiazines; Hydrogenated 1,4-thiazines
    • C07D279/12—1,4-Thiazines; Hydrogenated 1,4-thiazines not condensed with other rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

ESTA INVENCION SE RELACIONA CON POLIMORFOS CRISTALINOS DE (3S)-N-HIDROXI-4-({4-[(4-HIDROXI-2-BUTINI)OXI]FENIL}SULFONIL)-2,2-DIMETIL-3-TIOMORFOLINA CARBOXAMIDA, Y CON SU PREPARACION Y USOS.
PA20058636301A 2004-06-08 2005-06-08 Polimorfos cristalinos de (3s)-n-hidroxi-4-({4-[(4-hidroxi-2-butinil)oxi]fenil} sulfonil)-2,2-dimetil-3-tiomorfolina carboxamida PA8636301A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US57778404P 2004-06-08 2004-06-08

Publications (1)

Publication Number Publication Date
PA8636301A1 true PA8636301A1 (es) 2006-03-24

Family

ID=35106941

Family Applications (2)

Application Number Title Priority Date Filing Date
PA20058636101A PA8636101A1 (es) 2004-06-08 2005-06-08 Metodo para la preparacion de acidos hidroxamicos
PA20058636301A PA8636301A1 (es) 2004-06-08 2005-06-08 Polimorfos cristalinos de (3s)-n-hidroxi-4-({4-[(4-hidroxi-2-butinil)oxi]fenil} sulfonil)-2,2-dimetil-3-tiomorfolina carboxamida

Family Applications Before (1)

Application Number Title Priority Date Filing Date
PA20058636101A PA8636101A1 (es) 2004-06-08 2005-06-08 Metodo para la preparacion de acidos hidroxamicos

Country Status (6)

Country Link
US (2) US7179911B2 (es)
AR (2) AR049073A1 (es)
GT (1) GT200500139A (es)
PA (2) PA8636101A1 (es)
TW (2) TW200610523A (es)
WO (2) WO2005123706A1 (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT1682537E (pt) 2003-11-05 2012-06-20 Sarcode Bioscience Inc Moduladores de adesão celular
GT200500139A (es) * 2004-06-08 2005-07-25 Metodo para la preparacion de acidos hidroxamicos
DK1881823T3 (en) 2005-05-17 2015-03-02 Sarcode Bioscience Inc COMPOSITION AND PROCEDURES FOR TREATMENT OF EYE DISORDERS
FR2898497B1 (fr) * 2006-03-20 2008-05-16 Galderma Res & Dev Utilisation de l'apratastat ou du (s)-n-hydroxy-4-(4-but-2- ynyloxy-benzenesulfonyl)-2,2-dimethyl-thiomorpholine-3-carbo xamide dans le traitement de pathologies inflammatoires cutanees
US7631568B2 (en) * 2007-08-28 2009-12-15 Quest Technologies Particulate monitor
ES2830024T3 (es) 2007-10-19 2021-06-02 Novartis Ag Composiciones y métodos para el tratamiento del edema macular
US8080562B2 (en) 2008-04-15 2011-12-20 Sarcode Bioscience Inc. Crystalline pharmaceutical and methods of preparation and use thereof
WO2011050175A1 (en) 2009-10-21 2011-04-28 Sarcode Corporation Crystalline pharmaceutical and methods of preparation and use thereof
EP2496079A4 (en) 2009-11-06 2014-05-14 Pierre Fabre Médicament Sas NOVEL (1S, 2R) -2- (AMINOMETHYL) -N, N-DIETHYL-1-PHENYLCYCLOPROPANECARBOXAMIDE CRYSTALLINE FORMS
CN110922393A (zh) 2012-07-25 2020-03-27 诺华股份有限公司 Lfa-1抑制剂及其多晶型物

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6153757A (en) 1995-12-08 2000-11-28 Agouron Pharmaceuticals, Inc. Metalloproteinase inhibitors and intermediates useful for their preparation
BR9807678A (pt) 1997-02-11 2000-02-15 Pfizer Derivados de ácidos arilsulfonil-hidroxâmicos
US6225311B1 (en) * 1999-01-27 2001-05-01 American Cyanamid Company Acetylenic α-amino acid-based sulfonamide hydroxamic acid tace inhibitors
US6387901B1 (en) 1999-07-06 2002-05-14 Pfizer Inc Alkyne containing metalloproteinase inhibitors
CA2357110A1 (en) * 2001-04-11 2002-10-11 American Cyanamid Company Method for the treatment of polycystic kidney disease
JP2005507937A (ja) 2001-11-01 2005-03-24 ワイス・ホールディングズ・コーポレイション マトリックスメタロプロテイナーゼおよびｔａｃｅ阻害剤としてのアレンアリールスルホンアミドヒドロキサム酸
GT200500139A (es) 2004-06-08 2005-07-25 Metodo para la preparacion de acidos hidroxamicos

Also Published As

Publication number Publication date
US20050272929A1 (en) 2005-12-08
AR049349A1 (es) 2006-07-19
US7179911B2 (en) 2007-02-20
PA8636101A1 (es) 2006-03-24
WO2005123706A9 (en) 2006-04-27
AR049073A1 (es) 2006-06-21
WO2005123705A1 (en) 2005-12-29
GT200500139A (es) 2005-07-25
US20050272928A1 (en) 2005-12-08
US7435732B2 (en) 2008-10-14
TW200610523A (en) 2006-04-01
TW200612959A (en) 2006-05-01
WO2005123706A1 (en) 2005-12-29

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