OA11642A - Transgenic amorpha-4, 11-diene synthesis. - Google Patents

Transgenic amorpha-4, 11-diene synthesis. Download PDF

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Publication number
OA11642A
OA11642A OA1200100047A OA1200100047A OA11642A OA 11642 A OA11642 A OA 11642A OA 1200100047 A OA1200100047 A OA 1200100047A OA 1200100047 A OA1200100047 A OA 1200100047A OA 11642 A OA11642 A OA 11642A
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Prior art keywords
cell
amorpha
transgenic
dna sequence
organism
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OA1200100047A
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English (en)
Inventor
Hendrik Jan Bouwmeester
Thorvald Eelco Wallaart
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Genoclipp Biotechnology B V
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Application filed by Genoclipp Biotechnology B V filed Critical Genoclipp Biotechnology B V
Publication of OA11642A publication Critical patent/OA11642A/en

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/18Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
    • C12P17/181Heterocyclic compounds containing oxygen atoms as the only ring heteroatoms in the condensed system, e.g. Salinomycin, Septamycin
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241Phenotypically and genetically modified plants via recombinant DNA technology
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8243Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88Lyases (4.)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/18Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P5/00Preparation of hydrocarbons or halogenated hydrocarbons
    • C12P5/007Preparation of hydrocarbons or halogenated hydrocarbons containing one or more isoprene units, i.e. terpenes

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Plant Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • Nutrition Science (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Holo Graphy (AREA)
  • Footwear And Its Accessory, Manufacturing Method And Apparatuses (AREA)
  • Processes Of Treating Macromolecular Substances (AREA)
  • Liquid Crystal Substances (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
OA1200100047A 1998-08-27 1999-08-27 Transgenic amorpha-4, 11-diene synthesis. OA11642A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP98202854A EP0982404A1 (en) 1998-08-27 1998-08-27 DNA encoding amorpha-4,11-diene synthase

Publications (1)

Publication Number Publication Date
OA11642A true OA11642A (en) 2004-11-22

Family

ID=8234064

Family Applications (1)

Application Number Title Priority Date Filing Date
OA1200100047A OA11642A (en) 1998-08-27 1999-08-27 Transgenic amorpha-4, 11-diene synthesis.

Country Status (19)

Country Link
US (2) US7091027B1 (zh)
EP (2) EP0982404A1 (zh)
JP (1) JP4638036B2 (zh)
CN (1) CN1253573C (zh)
AT (1) ATE348174T1 (zh)
AU (1) AU766764B2 (zh)
BR (1) BR9913196A (zh)
CA (1) CA2340925C (zh)
CY (1) CY1105926T1 (zh)
DE (1) DE69934413T2 (zh)
DK (1) DK1108041T3 (zh)
ES (1) ES2274636T3 (zh)
HK (1) HK1042516B (zh)
ID (1) ID28532A (zh)
MX (1) MXPA01002040A (zh)
OA (1) OA11642A (zh)
PT (1) PT1108041E (zh)
WO (1) WO2000012725A2 (zh)
ZA (1) ZA200101455B (zh)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0982404A1 (en) * 1998-08-27 2000-03-01 Wallaart, Thorvald Eelco DNA encoding amorpha-4,11-diene synthase
EP1231273A1 (en) 2001-02-12 2002-08-14 Plant Research International B.V. Terpene synthase/cyclase and olefin synthase and uses thereof
JP2005503163A (ja) * 2001-09-17 2005-02-03 プラント リサーチ インターナショナル ビー. ブイ. 生物的転化のための植物酵素
BRPI0513837B1 (pt) 2004-07-27 2021-10-13 The Regents Of The University Of California Célula hospedeira saccharomyces cerevisiae geneticamente modificada; composição compreendendo a mesma e método para aumentar a produção de isoprenoides
JP2008537878A (ja) 2005-03-18 2008-10-02 マイクロビア, インコーポレイテッド 含油性酵母および真菌におけるカロテノイドの産生
US8017835B2 (en) * 2005-04-19 2011-09-13 University Of Kentucky Research Foundation Transformed plants accumulating terpenes
ATE486133T1 (de) * 2005-07-01 2010-11-15 Univ Kentucky Res Found Transformierte pflanzen mit anreicherung von mono-und/oder sesquiterpenen
SG176459A1 (en) * 2005-07-05 2011-12-29 Univ California Polynucleotides encoding isoprenoid modifying enzymes and methods of use thereof
WO2008100251A1 (en) * 2007-02-13 2008-08-21 Ls9, Inc. Modified microorganism uses therefor
EP2204449A3 (en) 2006-04-05 2010-09-08 National Research Council of Canada Nucleotide sequences encoding enzymes in biosynthesis of dihydroartemisinic acid
US8110670B2 (en) 2006-05-19 2012-02-07 Ls9, Inc. Enhanced production of fatty acid derivatives
US20100242345A1 (en) 2006-05-19 2010-09-30 LS9, Inc Production of fatty acids & derivatives thereof
US8691555B2 (en) 2006-09-28 2014-04-08 Dsm Ip Assests B.V. Production of carotenoids in oleaginous yeast and fungi
CN101074443B (zh) * 2006-11-14 2011-08-03 西南大学 携带质体转运肽的紫槐二烯合成酶融合基因及应用
KR20110023862A (ko) * 2008-05-23 2011-03-08 시부스 오일즈, 엘엘씨 효모를 사용한 스쿠알렌 생산
US8481286B2 (en) * 2008-08-12 2013-07-09 Allylix, Inc. Method for production of isoprenoid compounds
WO2010054221A2 (en) 2008-11-06 2010-05-14 The Johns Hopkins University Treatment of chronic inflammatory respiratory disorders
WO2010126891A1 (en) 2009-04-27 2010-11-04 Ls9, Inc. Production of fatty acid esters
US9371537B2 (en) * 2009-09-25 2016-06-21 Basf Plant Science Company Gmbh Plants having enhanced yield-related traits resulted from modulated expression of a SGT1 polypeptide and a method for making the same
CN102242145A (zh) * 2011-04-20 2011-11-16 上海交通大学 转aoc基因提高青蒿中青蒿素含量的方法
CN103276000B (zh) * 2013-05-31 2015-02-04 天津大学 一种生产青蒿二烯的酵母菌及构建方法
JP6436417B2 (ja) * 2014-12-01 2018-12-12 住友ゴム工業株式会社 アモルファ−4,11−ジエン増産方法及び天然ゴム増産方法
CN112877355A (zh) * 2021-01-22 2021-06-01 杜云龙 一种利用烟草表达三七皂苷的方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994000584A2 (en) * 1992-06-23 1994-01-06 Worcester Polytechnic Institute Artemisia annua transformed with agrobacterium rhizogenes
AU2490399A (en) * 1998-02-02 1999-08-16 Regents Of The University Of California, The Germacrene c synthase gene of (lycopersicon esculentum)
EP0982404A1 (en) * 1998-08-27 2000-03-01 Wallaart, Thorvald Eelco DNA encoding amorpha-4,11-diene synthase
AR022383A1 (es) 1998-09-18 2002-09-04 Univ Kentucky Res Found Sintasas

Also Published As

Publication number Publication date
US7091027B1 (en) 2006-08-15
DE69934413T2 (de) 2007-09-27
AU766764B2 (en) 2003-10-23
US20070031947A1 (en) 2007-02-08
CA2340925C (en) 2011-07-12
CY1105926T1 (el) 2011-04-06
DE69934413D1 (de) 2007-01-25
AU5742399A (en) 2000-03-21
US7541172B2 (en) 2009-06-02
JP2002523101A (ja) 2002-07-30
EP0982404A1 (en) 2000-03-01
ES2274636T3 (es) 2007-05-16
DK1108041T3 (da) 2007-04-10
ID28532A (id) 2001-05-31
WO2000012725A2 (en) 2000-03-09
ZA200101455B (en) 2001-08-28
ATE348174T1 (de) 2007-01-15
PT1108041E (pt) 2007-03-30
EP1108041B1 (en) 2006-12-13
CN1321194A (zh) 2001-11-07
HK1042516B (zh) 2006-09-29
CN1253573C (zh) 2006-04-26
JP4638036B2 (ja) 2011-02-23
WO2000012725A3 (en) 2000-06-02
CA2340925A1 (en) 2000-03-09
BR9913196A (pt) 2001-09-25
MXPA01002040A (es) 2002-04-24
EP1108041A2 (en) 2001-06-20
HK1042516A1 (en) 2002-08-16

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