OA11149A - Gene sequencer and methods - Google Patents
Gene sequencer and methods Download PDFInfo
- Publication number
- OA11149A OA11149A OA9900184A OA9900184A OA11149A OA 11149 A OA11149 A OA 11149A OA 9900184 A OA9900184 A OA 9900184A OA 9900184 A OA9900184 A OA 9900184A OA 11149 A OA11149 A OA 11149A
- Authority
- OA
- OAPI
- Prior art keywords
- mer
- oligonucleotides
- sample
- oligonucleotide
- spacer
- Prior art date
Links
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J19/0046—Sequential or parallel reactions, e.g. for the synthesis of polypeptides or polynucleotides; Apparatus and devices for combinatorial chemistry or for making molecular arrays
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y30/00—Nanotechnology for materials or surface science, e.g. nanocomposites
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
- C12Q1/6837—Enzymatic or biochemical coupling of nucleic acids to a solid phase using probe arrays or probe chips
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6869—Methods for sequencing
- C12Q1/6874—Methods for sequencing involving nucleic acid arrays, e.g. sequencing by hybridisation
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00497—Features relating to the solid phase supports
- B01J2219/005—Beads
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00497—Features relating to the solid phase supports
- B01J2219/00527—Sheets
- B01J2219/00536—Sheets in the shape of disks
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00585—Parallel processes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00596—Solid-phase processes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
- B01J2219/0061—The surface being organic
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
- B01J2219/00614—Delimitation of the attachment areas
- B01J2219/00617—Delimitation of the attachment areas by chemical means
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
- B01J2219/00614—Delimitation of the attachment areas
- B01J2219/00617—Delimitation of the attachment areas by chemical means
- B01J2219/00619—Delimitation of the attachment areas by chemical means using hydrophilic or hydrophobic regions
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
- B01J2219/00614—Delimitation of the attachment areas
- B01J2219/00621—Delimitation of the attachment areas by physical means, e.g. trenches, raised areas
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
- B01J2219/00623—Immobilisation or binding
- B01J2219/00626—Covalent
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
- B01J2219/00623—Immobilisation or binding
- B01J2219/0063—Other, e.g. van der Waals forces, hydrogen bonding
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
- B01J2219/00632—Introduction of reactive groups to the surface
- B01J2219/00635—Introduction of reactive groups to the surface by reactive plasma treatment
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
- B01J2219/00632—Introduction of reactive groups to the surface
- B01J2219/00637—Introduction of reactive groups to the surface by coating it with another layer
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00639—Making arrays on substantially continuous surfaces the compounds being trapped in or bound to a porous medium
- B01J2219/00644—Making arrays on substantially continuous surfaces the compounds being trapped in or bound to a porous medium the porous medium being present in discrete locations, e.g. gel pads
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00646—Making arrays on substantially continuous surfaces the compounds being bound to beads immobilised on the solid supports
- B01J2219/00648—Making arrays on substantially continuous surfaces the compounds being bound to beads immobilised on the solid supports by the use of solid beads
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00659—Two-dimensional arrays
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00709—Type of synthesis
- B01J2219/00711—Light-directed synthesis
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00718—Type of compounds synthesised
- B01J2219/0072—Organic compounds
- B01J2219/00722—Nucleotides
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B40/00—Libraries per se, e.g. arrays, mixtures
- C40B40/04—Libraries containing only organic compounds
- C40B40/06—Libraries containing nucleotides or polynucleotides, or derivatives thereof
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/00029—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor provided with flat sample substrates, e.g. slides
- G01N35/00069—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor provided with flat sample substrates, e.g. slides whereby the sample substrate is of the bio-disk type, i.e. having the format of an optical disk
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Analytical Chemistry (AREA)
- Nanotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Composite Materials (AREA)
- Condensed Matter Physics & Semiconductors (AREA)
- General Physics & Mathematics (AREA)
- Materials Engineering (AREA)
- Crystallography & Structural Chemistry (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US3902797P | 1997-02-21 | 1997-02-21 |
Publications (1)
Publication Number | Publication Date |
---|---|
OA11149A true OA11149A (en) | 2003-04-25 |
Family
ID=21903274
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
OA9900184A OA11149A (en) | 1997-02-21 | 1999-08-19 | Gene sequencer and methods |
Country Status (22)
Country | Link |
---|---|
US (2) | US6274373B1 (zh) |
EP (1) | EP0968307A1 (zh) |
JP (1) | JP2001512975A (zh) |
KR (1) | KR20000075555A (zh) |
CN (1) | CN1251617A (zh) |
AP (1) | AP9901654A0 (zh) |
AU (1) | AU745673B2 (zh) |
BR (1) | BR9808646A (zh) |
CA (1) | CA2281764A1 (zh) |
EE (1) | EE9900357A (zh) |
HU (1) | HUP0002038A2 (zh) |
ID (1) | ID22708A (zh) |
IL (1) | IL131486A0 (zh) |
IS (1) | IS5158A (zh) |
NO (1) | NO994009L (zh) |
NZ (1) | NZ337893A (zh) |
OA (1) | OA11149A (zh) |
PL (1) | PL335226A1 (zh) |
SG (2) | SG105505A1 (zh) |
SK (1) | SK114499A3 (zh) |
TR (1) | TR199902473T2 (zh) |
WO (1) | WO1998037238A2 (zh) |
Families Citing this family (37)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9418981D0 (en) | 1994-09-21 | 1994-11-09 | Univ Glasgow | Apparatus and method for carrying out analysis of samples |
US6327031B1 (en) | 1998-09-18 | 2001-12-04 | Burstein Technologies, Inc. | Apparatus and semi-reflective optical system for carrying out analysis of samples |
IL151635A0 (en) | 1996-07-08 | 2003-04-10 | Burstein Technologies Inc | Cleavable signal element device for diagnostic applications and assay method |
US6331275B1 (en) | 1996-07-08 | 2001-12-18 | Burstein Technologies, Inc. | Spatially addressable, cleavable reflective signal elements, assay device and method |
US6342349B1 (en) | 1996-07-08 | 2002-01-29 | Burstein Technologies, Inc. | Optical disk-based assay devices and methods |
JP3394181B2 (ja) * | 1998-03-30 | 2003-04-07 | 日立ソフトウエアエンジニアリング株式会社 | 試料添加方法及び試料添加装置 |
AU5080699A (en) * | 1998-07-21 | 2000-02-14 | Burstein Laboratories, Inc. | Optical disc-based assay devices and methods |
KR100369694B1 (ko) * | 1998-09-17 | 2003-01-29 | 인터내셔널 비지네스 머신즈 코포레이션 | 화학적 태그의 합성 방법 |
US20040185462A1 (en) * | 1999-08-06 | 2004-09-23 | Tum Gene, Inc. | Method of and detecting apparatus and detecting chip for single base substitution SNP and point mutation of genes |
US6888951B1 (en) | 1999-08-23 | 2005-05-03 | Nagaoka & Co., Ltd. | Methods and apparatus for analyzing operational and analyte data acquired from optical disc |
EP1146331B1 (en) | 1999-10-20 | 2008-09-10 | Shigeori Takenaka | Gene detecting chip, detector, and detecting method |
AU2002227181A1 (en) | 2000-11-16 | 2002-05-27 | Burstein Technologies, Inc. | Optical biodiscs with reflective layers |
US7079468B2 (en) | 2000-12-08 | 2006-07-18 | Burstein Technologies, Inc. | Optical discs for measuring analytes |
US7054258B2 (en) | 2000-12-08 | 2006-05-30 | Nagaoka & Co., Ltd. | Optical disc assemblies for performing assays |
DE10113711A1 (de) * | 2001-03-16 | 2002-09-26 | Lifebits Ag | Verfahren zum Nachweis biochemischer Reaktionen und Messträger zur Durchführung des Verfahrens |
WO2002090599A1 (en) * | 2001-05-09 | 2002-11-14 | Genetic Id, Inc. | Universal microarray system |
US20030194798A1 (en) * | 2001-05-24 | 2003-10-16 | Surber Mark W. | Minicell compositions and methods |
US20040166593A1 (en) * | 2001-06-22 | 2004-08-26 | Nolte David D. | Adaptive interferometric multi-analyte high-speed biosensor |
AU2003251986A1 (en) * | 2002-07-17 | 2004-02-02 | U.S.Genomics, Inc. | Methods and compositions for analyzing polymers using chimeric tags |
EP1620203A2 (en) * | 2003-04-10 | 2006-02-01 | U.S. Genomics, Inc. | Manipulation of polymers in a microchannel |
EP1660870A2 (en) * | 2003-08-26 | 2006-05-31 | Blueshift Biotechnologies, Inc. | Time dependent fluorescence measurements |
US20050264805A1 (en) * | 2004-02-09 | 2005-12-01 | Blueshift Biotechnologies, Inc. | Methods and apparatus for scanning small sample volumes |
WO2006014351A2 (en) | 2004-07-02 | 2006-02-09 | Blueshift Biotechnologies, Inc. | Exploring fluorophore microenvironments |
US20060040273A1 (en) * | 2004-08-17 | 2006-02-23 | Alison Chaiken | Method and apparatus for magnetic sensing and control of reagents |
US20070023643A1 (en) * | 2005-02-01 | 2007-02-01 | Nolte David D | Differentially encoded biological analyzer planar array apparatus and methods |
WO2006083915A1 (en) * | 2005-02-01 | 2006-08-10 | Purdue Research Foundation | Multiplexed and differentially encoded biological analyzer planar array apparatus and methods |
US7910356B2 (en) * | 2005-02-01 | 2011-03-22 | Purdue Research Foundation | Multiplexed biological analyzer planar array apparatus and methods |
US7663092B2 (en) * | 2005-02-01 | 2010-02-16 | Purdue Research Foundation | Method and apparatus for phase contrast quadrature interferometric detection of an immunoassay |
US20070128083A1 (en) * | 2005-07-18 | 2007-06-07 | U.S. Genomics, Inc. | Microfluidic methods and apparatuses for sample preparation and analysis |
US20070259366A1 (en) * | 2006-05-03 | 2007-11-08 | Greg Lawrence | Direct printing of patterned hydrophobic wells |
US20080230605A1 (en) * | 2006-11-30 | 2008-09-25 | Brian Weichel | Process and apparatus for maintaining data integrity |
US7522282B2 (en) * | 2006-11-30 | 2009-04-21 | Purdue Research Foundation | Molecular interferometric imaging process and apparatus |
US20080144899A1 (en) * | 2006-11-30 | 2008-06-19 | Manoj Varma | Process for extracting periodic features from images by template matching |
WO2008089495A2 (en) | 2007-01-19 | 2008-07-24 | Purdue Research Foundation | System with extended range of molecular sensing through integrated multi-modal data acquisition |
US7787126B2 (en) * | 2007-03-26 | 2010-08-31 | Purdue Research Foundation | Method and apparatus for conjugate quadrature interferometric detection of an immunoassay |
EP2871243B1 (en) * | 2013-11-06 | 2018-03-21 | Omya International AG | Nucleic acids and methods for detecting pathogens and beneficial microorganisms |
WO2019218262A1 (zh) * | 2018-05-16 | 2019-11-21 | 深圳华大智造科技有限公司 | 基因测序仪 |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5118605A (en) * | 1984-10-16 | 1992-06-02 | Chiron Corporation | Polynucleotide determination with selectable cleavage sites |
US5474796A (en) * | 1991-09-04 | 1995-12-12 | Protogene Laboratories, Inc. | Method and apparatus for conducting an array of chemical reactions on a support surface |
US5412087A (en) * | 1992-04-24 | 1995-05-02 | Affymax Technologies N.V. | Spatially-addressable immobilization of oligonucleotides and other biological polymers on surfaces |
CA2130562A1 (en) * | 1992-02-19 | 1993-09-02 | Alexander B. Chetverin | Novel oligonucleotide arrays and their use for sorting, isolating, sequencing, and manipulating nucleic acids |
EP0705271B1 (en) * | 1993-06-25 | 2002-11-13 | Affymetrix, Inc. (a Delaware Corporation) | Hybridization and sequencing of nucleic acids |
AU694146B2 (en) * | 1993-09-27 | 1998-07-16 | Arch Development Corporation | Methods and compositions for efficient nucleic acid sequencing |
US6974666B1 (en) * | 1994-10-21 | 2005-12-13 | Appymetric, Inc. | Methods of enzymatic discrimination enhancement and surface-bound double-stranded DNA |
US5585069A (en) * | 1994-11-10 | 1996-12-17 | David Sarnoff Research Center, Inc. | Partitioned microelectronic and fluidic device array for clinical diagnostics and chemical synthesis |
JPH08189379A (ja) | 1995-01-10 | 1996-07-23 | Mitsubishi Heavy Ind Ltd | 外部燃焼型ガスタービン装置 |
IL151635A0 (en) * | 1996-07-08 | 2003-04-10 | Burstein Technologies Inc | Cleavable signal element device for diagnostic applications and assay method |
-
1998
- 1998-02-20 AP APAP/P/1999/001654A patent/AP9901654A0/en unknown
- 1998-02-20 ID IDW991072A patent/ID22708A/id unknown
- 1998-02-20 NZ NZ337893A patent/NZ337893A/en unknown
- 1998-02-20 SG SG200105096A patent/SG105505A1/en unknown
- 1998-02-20 SK SK1144-99A patent/SK114499A3/sk unknown
- 1998-02-20 AU AU66621/98A patent/AU745673B2/en not_active Ceased
- 1998-02-20 IL IL13148698A patent/IL131486A0/xx unknown
- 1998-02-20 EP EP98908634A patent/EP0968307A1/en not_active Withdrawn
- 1998-02-20 BR BR9808646-4A patent/BR9808646A/pt not_active IP Right Cessation
- 1998-02-20 TR TR1999/02473T patent/TR199902473T2/xx unknown
- 1998-02-20 CA CA002281764A patent/CA2281764A1/en not_active Abandoned
- 1998-02-20 SG SG200105097A patent/SG105506A1/en unknown
- 1998-02-20 HU HU0002038A patent/HUP0002038A2/hu unknown
- 1998-02-20 JP JP53691598A patent/JP2001512975A/ja not_active Ceased
- 1998-02-20 PL PL98335226A patent/PL335226A1/xx unknown
- 1998-02-20 CN CN98803767A patent/CN1251617A/zh active Pending
- 1998-02-20 KR KR1019997007615A patent/KR20000075555A/ko not_active Application Discontinuation
- 1998-02-20 EE EEP199900357A patent/EE9900357A/xx unknown
- 1998-02-20 WO PCT/US1998/003362 patent/WO1998037238A2/en not_active Application Discontinuation
-
1999
- 1999-08-19 OA OA9900184A patent/OA11149A/en unknown
- 1999-08-19 NO NO994009A patent/NO994009L/no not_active Application Discontinuation
- 1999-08-20 IS IS5158A patent/IS5158A/is unknown
-
2000
- 2000-05-01 US US09/564,399 patent/US6274373B1/en not_active Expired - Fee Related
-
2001
- 2001-05-21 US US09/861,787 patent/US6566069B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
US6566069B2 (en) | 2003-05-20 |
US6274373B1 (en) | 2001-08-14 |
PL335226A1 (en) | 2000-04-10 |
KR20000075555A (ko) | 2000-12-15 |
SG105506A1 (en) | 2004-08-27 |
NZ337893A (en) | 2001-09-28 |
AU745673B2 (en) | 2002-03-28 |
SG105505A1 (en) | 2004-08-27 |
HUP0002038A2 (hu) | 2000-10-28 |
WO1998037238A3 (en) | 1998-10-29 |
CA2281764A1 (en) | 1998-08-27 |
SK114499A3 (en) | 2000-09-12 |
NO994009D0 (no) | 1999-08-19 |
BR9808646A (pt) | 2001-07-31 |
CN1251617A (zh) | 2000-04-26 |
AU6662198A (en) | 1998-09-09 |
NO994009L (no) | 1999-10-21 |
JP2001512975A (ja) | 2001-08-28 |
US20020045174A1 (en) | 2002-04-18 |
AP9901654A0 (en) | 1999-09-30 |
TR199902473T2 (xx) | 2000-07-21 |
EE9900357A (et) | 2000-02-15 |
ID22708A (id) | 1999-12-09 |
EP0968307A1 (en) | 2000-01-05 |
IS5158A (is) | 1999-08-20 |
WO1998037238A2 (en) | 1998-08-27 |
IL131486A0 (en) | 2001-01-28 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
OA11149A (en) | Gene sequencer and methods | |
US6218118B1 (en) | Method and mixture reagents for analyzing the nucleotide sequence of nucleic acids by mass spectrometry | |
US5631134A (en) | Methods of preparing probe array by hybridation | |
Drmanac et al. | Sequencing by hybridization (SBH): advantages, achievements, and opportunities | |
Rogers et al. | Immobilization of oligonucleotides onto a glass support via disulfide bonds: a method for preparation of DNA microarrays | |
Chetverin et al. | Oligonucleotide arrays: New concepts and possibilities | |
US6268210B1 (en) | Sandwich arrays of biological compounds | |
US20060040314A1 (en) | Methods for screening polypeptides | |
US7399844B2 (en) | Method and reagents for analyzing the nucleotide sequence of nucleic acids | |
EP0668932B1 (en) | Positional sequencing by hybridization | |
US6027880A (en) | Arrays of nucleic acid probes and methods of using the same for detecting cystic fibrosis | |
US7771975B2 (en) | Polynucleotide analysis using combinatorial PCR | |
KR20000070230A (ko) | 핵산 종을 감지하고 이를 정량화하는 방법 및 그 조성물 | |
US6423552B1 (en) | Method for the preparation of compound micro array chips and the compound micro array chips produced according to said method | |
KR100624467B1 (ko) | 전기수력학적(electrohydrodynamic)현상을 이용하여 기판 상에 생체분자를 프린팅하는 장치 | |
Jaklevic et al. | Instrumentation for the genome project | |
US20020042069A1 (en) | Long-length oligonucleotide microarrays | |
AU776614B2 (en) | Gene sequencer and methods | |
US20090239770A1 (en) | Detection oligomer and method for controlling quality of biochip using detection oligomer | |
Souteyrand et al. | Use of microtechnology for DNA chips implementation | |
NZ512488A (en) | Gene sequencer and methods suitable for long repeat sequences | |
MXPA99007738A (es) | Secuenciador de genes y metodos | |
US20020172960A1 (en) | DNA microarrays of networked oligonucleotides | |
Zhou et al. | DNA microarray technology | |
Cullen et al. | High‐Throughput and Industrial Methods for mRNA Expression Analysis |