OA07644A - Dérivés de la pyridazine amino -substitués en position 3, actifs sur le système nerveux central, procédé d'obtention et médicaments en contenant. - Google Patents

Dérivés de la pyridazine amino -substitués en position 3, actifs sur le système nerveux central, procédé d'obtention et médicaments en contenant.

Info

Publication number
OA07644A
OA07644A OA58216A OA58216A OA07644A OA 07644 A OA07644 A OA 07644A OA 58216 A OA58216 A OA 58216A OA 58216 A OA58216 A OA 58216A OA 07644 A OA07644 A OA 07644A
Authority
OA
OAPI
Prior art keywords
substituted
obtaining
active
nervous system
central nervous
Prior art date
Application number
OA58216A
Other languages
English (en)
French (fr)
Inventor
Jean-Ppierre Chambon
Kathleen Biziere
Camille-George Wermuth
Original Assignee
Sanofi Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Sa filed Critical Sanofi Sa
Publication of OA07644A publication Critical patent/OA07644A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/26Psychostimulants, e.g. nicotine, cocaine
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D237/00Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/02Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
    • C07D237/06Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D237/10Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D237/20Nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D237/00Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/02Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
    • C07D237/06Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D237/10Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D237/24Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Psychiatry (AREA)
  • Anesthesiology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
OA58216A 1983-01-27 1984-01-26 Dérivés de la pyridazine amino -substitués en position 3, actifs sur le système nerveux central, procédé d'obtention et médicaments en contenant. OA07644A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8301234A FR2540113A1 (fr) 1983-01-27 1983-01-27 Acides derives de la pyridazine actifs sur le systeme nerveux central

Publications (1)

Publication Number Publication Date
OA07644A true OA07644A (fr) 1985-05-23

Family

ID=9285330

Family Applications (1)

Application Number Title Priority Date Filing Date
OA58216A OA07644A (fr) 1983-01-27 1984-01-26 Dérivés de la pyridazine amino -substitués en position 3, actifs sur le système nerveux central, procédé d'obtention et médicaments en contenant.

Country Status (27)

Country Link
US (1) US4721711A (fi)
EP (1) EP0117779B1 (fi)
JP (1) JPS59141564A (fi)
KR (1) KR910000638B1 (fi)
AR (1) AR240045A1 (fi)
AT (1) ATE48417T1 (fi)
AU (2) AU2372984A (fi)
CA (1) CA1238637A (fi)
DD (1) DD220026A5 (fi)
DE (1) DE3480653D1 (fi)
DK (1) DK162985C (fi)
ES (1) ES529081A0 (fi)
FI (1) FI78691C (fi)
FR (1) FR2540113A1 (fi)
HU (1) HU193890B (fi)
IE (1) IE57054B1 (fi)
IL (1) IL70756A (fi)
MA (1) MA20018A1 (fi)
NO (1) NO840313L (fi)
NZ (1) NZ206945A (fi)
OA (1) OA07644A (fi)
PH (1) PH21162A (fi)
PL (1) PL142340B1 (fi)
PT (1) PT77993B (fi)
SG (1) SG93690G (fi)
YU (1) YU14284A (fi)
ZA (1) ZA84502B (fi)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2540113A1 (fr) * 1983-01-27 1984-08-03 Sanofi Sa Acides derives de la pyridazine actifs sur le systeme nerveux central
DE3664772D1 (en) * 1985-01-14 1989-09-07 Boehringer Ingelheim Kg 12-amino pyridazinoû4',5':3,4¨pyrroloû2,1-a¨isoquinolines, process for their preparation and use
US5082939A (en) * 1987-01-08 1992-01-21 I.S.F. Societa Per Azioni Pyridazine derivatives
US5106973A (en) * 1987-11-23 1992-04-21 Janssen Pharmaceutica N.V. Pyridzainamine derivatives
US5656631A (en) * 1989-02-07 1997-08-12 Sanofi Pyridazine derivatives
FR2663326B2 (fr) * 1989-11-17 1992-10-16 Sanofi Sa Derives de la pyridazine, procede de preparation et compositions pharmaceutiques en contenant.
FR2668151A1 (fr) * 1990-10-23 1992-04-24 Rhone Poulenc Agrochimie Composes a groupe triazolopyridazine leurs preparations et compositions herbicides les contenant.
FR2676444B1 (fr) * 1991-05-16 1995-03-10 Sanofi Elf Nouveaux derives d'amino-3 pyridazines actifs sur le systeme nerveux central, procede de preparation et compositions pharmaceutiques en contenant.
CN1038249C (zh) * 1991-08-28 1998-05-06 罗姆和哈斯公司 含有二氢哒嗪酮及其相关化合物的杀菌组合物
US20100210590A1 (en) * 1995-09-27 2010-08-19 Northwestern University Compositions and treatments for seizure-related disorders
US20030176437A1 (en) * 2001-08-31 2003-09-18 D.M. Watterson Anti-inflammatory and protein kinase inhibitor compositions and related methods for downregulation of detrimental cellular responses and inhibition of cell death
EP2592075B1 (en) 2004-11-02 2015-04-29 Northwestern University Pyridazine compounds for the treatment of inflammatory diseases
CA2589102C (en) * 2004-11-02 2013-08-13 Northwestern University Pyridazine compounds and methods for using the compounds to treat inflammatory diseases
EP2015751A2 (en) * 2006-04-28 2009-01-21 Northwestern University Salts of pyridazine compounds
US20090325973A1 (en) * 2006-04-28 2009-12-31 Watterson D Martin Formulations containing pyridazine compounds
EP2015750A2 (en) * 2006-04-28 2009-01-21 Northwestern University Compositions and treatments using pyridazine compounds and cholinesterase inhibitors
KR20100016073A (ko) * 2007-04-02 2010-02-12 인스티튜트 포 원월드 헬스 Cftr 억제제 화합물 및 이의 용도
US20090264433A1 (en) * 2008-04-21 2009-10-22 Institute For Oneworld Health Compounds, Compositions and Methods Comprising Triazine Derivatives
EP2278879B1 (en) 2008-04-21 2016-06-15 PATH Drug Solutions Compounds, compositions and methods comprising oxadiazole derivatives
WO2009131951A2 (en) * 2008-04-21 2009-10-29 Institute For Oneworld Health Compounds, compositions and methods comprising isoxazole derivatives
US20090270398A1 (en) * 2008-04-21 2009-10-29 Institute For Oneworld Health Compounds, Compositions and Methods Comprising Pyridazine Derivatives
EP2341776A4 (en) * 2008-09-19 2012-05-30 Inst Oneworld Health COMPOUNDS, COMPOSITIONS AND METHODS COMPRISING IMIDAZOL AND TRIAZOL DERIVATIVES
US20100267706A1 (en) * 2009-04-20 2010-10-21 Institute For Oneworld Health Compounds, Compositions and Methods Comprising Pyridazine Derivatives
US8343976B2 (en) * 2009-04-20 2013-01-01 Institute For Oneworld Health Compounds, compositions and methods comprising pyrazole derivatives

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2510998B1 (fr) * 1981-08-07 1986-01-10 Sanofi Sa Nouveaux derives amines de la pyridazine, leur procede de preparation et les medicaments, a action desinhibitrice, qui en comportent
FR2510997A1 (fr) * 1981-08-10 1983-02-11 Sanofi Sa Nouveaux derives de la methyl-4 phenyl-6 pyridazine, procede pour leur preparation et medicaments actifs sur le systeme nerveux central en contenant
FR2540113A1 (fr) * 1983-01-27 1984-08-03 Sanofi Sa Acides derives de la pyridazine actifs sur le systeme nerveux central
US4565814A (en) * 1983-01-28 1986-01-21 Sanofi Pyridazine derivatives having a psychotropic action and compositions

Also Published As

Publication number Publication date
PT77993A (fr) 1984-02-01
FI840323A (fi) 1984-07-28
EP0117779A1 (fr) 1984-09-05
NZ206945A (en) 1987-07-31
FI78691B (fi) 1989-05-31
FI840323A0 (fi) 1984-01-26
IL70756A (en) 1987-03-31
DD220026A5 (de) 1985-03-20
EP0117779B1 (fr) 1989-12-06
IE57054B1 (en) 1992-04-08
ZA84502B (en) 1984-09-26
PH21162A (en) 1987-08-05
AU2372984A (en) 1984-08-02
JPS59141564A (ja) 1984-08-14
AU652118B2 (en) 1994-08-18
DK38984A (da) 1984-07-28
FR2540113A1 (fr) 1984-08-03
PL142340B1 (en) 1987-10-31
DK162985C (da) 1992-06-01
ES8500243A1 (es) 1984-10-01
PL245931A1 (en) 1985-07-16
SG93690G (en) 1991-01-18
DE3480653D1 (de) 1990-01-11
KR910000638B1 (ko) 1991-01-31
IL70756A0 (en) 1984-04-30
PT77993B (fr) 1986-04-10
FR2540113B1 (fi) 1985-05-17
NO840313L (no) 1984-07-30
DK38984D0 (da) 1984-01-27
DK162985B (da) 1992-01-06
ATE48417T1 (de) 1989-12-15
CA1238637A (en) 1988-06-28
KR840007586A (ko) 1984-12-08
FI78691C (fi) 1989-09-11
US4721711A (en) 1988-01-26
ES529081A0 (es) 1984-10-01
AR240045A1 (es) 1990-01-31
IE840149L (en) 1984-07-27
HU193890B (en) 1987-12-28
YU14284A (en) 1986-12-31
MA20018A1 (fr) 1984-10-01
AU2142188A (en) 1989-03-16

Similar Documents

Publication Publication Date Title
OA07644A (fr) Dérivés de la pyridazine amino -substitués en position 3, actifs sur le système nerveux central, procédé d'obtention et médicaments en contenant.
OA08871A (fr) Nouveaux dérivés de thiazole actif sur le système cholinergique, procédé d'obtention et compositions pharmaceutiques en contenant.
EP0556387A4 (en) PROCESS FOR THE PREPARATION OF OPTICALLY ACTIVE 1,3-BUTANEDIOL.
DE3788244T2 (de) Pharmakologisch wirksame 3-substituierte 1,5-Diaryl-pyrazole und Verfahren zu ihrer Herstellung.
BE876815A (fr) Polymere synthetique, procede d'obtention et application a titre d'agent apaississant
OA07175A (fr) Nouveaux dérivés de la pyridazine actifs sur le système nerveux central.
FR2709754B1 (fr) Composés 2' ou 3'-déoxy- et 2', 3'-didéoxy-beta-L-pentofuranonucléosides, procédé de préparation et application thérapeutique, notamment anti-virale.
DE69013317T2 (de) Kode-multiplex-vielfachzugriffsystem mit durch teilnehmerstimme aktiviertem träger und kode-synchronisation.
DZ1488A1 (fr) Système et procédé d'irrigation.
DE68920061T2 (de) Hydrofile, feine Gelpartikel und Verfahren zu deren Herstellung.
OA06920A (fr) Halogénures d'ammonium spiro-quartenaire, leur procédé de préparation et leur utilisation dans un procédé de production de N-(2-pyrimidinyl) pipérazinyl-alkylazospiro-alcanédiones.
OA07645A (fr) Dérivés de la pyridazine ayant une action psychotrope, procédé d'obtention, intermédiaires et médicaments en contenant.
DE3888530D1 (de) 3'-Azido-2',3'-dideoxynucleosid-5'-phosphonate.
MA21748A1 (fr) Procede d'obtention de nouvelles tetrahydroimidazo [1,4] bensodiazepin-2-thiones antivirales et leur preparation .
DE3770661D1 (de) 1,2,3,4-tetrahydro-6-substituierte-4-aryl(oder heterozyklo)3-((substituierte amino)carbonyl)-2-thioxo(oder oxo)-5-pyrimidinkarbonsaeuren und -ester.
DE3650211D1 (de) Polyätherhomo- oder -copolymer, Monomer dafür und Verfahren zu deren Herstellung.
FR2665175B1 (fr) Equivalent d'epiderme, son procede d'obtention et son utilisation.
FR2628933B1 (fr) Dispositif pour recolter des ombelles, notamment d'oignons ou de poireaux
HUT53774A (en) Antidotums containing 2,3-substituted 1,8-naphtiridines, antidoted herbicide kompositions and process for producing the active components
FR2504526B1 (fr) Derives de l'amidine, leur procede de preparation et agents anti-complement en contenant
NL193614B (nl) Werkwijze voor de bereiding van 4,5-tri- en -tetramethyleen-4-isothiazoline-3-onen, 2-alkyl- of -aralkylthio-1-cycloalkeencarbonamiden ten gebruike bij deze werkwijze en werkwijze voor de bereiding van de 2-alkyl- of -aralkylthio-1-cycloalkeencarbonamiden.
FR2518881B1 (fr) Medicaments a base de 26,23-lactones de la 25-hydroxyvitamine d3, utiles notamment pour agir sur la concentration en calcium du serum
ATE57935T1 (de) 16,17-acetalsubstituierte pregnan-21-saeure, verfahren zu deren herstellung und diese enthaltende pharmazeutische praeparate.
DK642687D0 (da) N,n'-disubstituerede urinstoffer samt fremgangsmaade til fremstilling deraf
FR2666591B1 (fr) Procede et dispositif de recuperation selective des ions argent en solution, composition eluante de recuperation et utilisation d'une telle composition.