OA05707A - Nouvelles quinazolines, leurs procédés d'obtention et leur application à la thérapeutique - Google Patents
Nouvelles quinazolines, leurs procédés d'obtention et leur application à la thérapeutiqueInfo
- Publication number
- OA05707A OA05707A OA56223A OA56223A OA05707A OA 05707 A OA05707 A OA 05707A OA 56223 A OA56223 A OA 56223A OA 56223 A OA56223 A OA 56223A OA 05707 A OA05707 A OA 05707A
- Authority
- OA
- OAPI
- Prior art keywords
- therapy
- application
- production processes
- quinazolines
- new
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title 1
- 150000003246 quinazolines Chemical class 0.000 title 1
- 238000002560 therapeutic procedure Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/56—Nitrogen atoms
- C07D211/58—Nitrogen atoms attached in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D211/72—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D211/72—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D211/74—Oxygen atoms
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Cardiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Heart & Thoracic Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB29317/76A GB1583753A (en) | 1976-07-14 | 1976-07-14 | Piperidine derivatives processes for their preparation and pharmaceutical compositions containing them |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| OA05707A true OA05707A (fr) | 1981-05-31 |
Family
ID=10289639
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| OA56223A OA05707A (fr) | 1976-07-14 | 1977-07-12 | Nouvelles quinazolines, leurs procédés d'obtention et leur application à la thérapeutique |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US4166117A (fr) |
| JP (1) | JPS5334784A (fr) |
| BE (1) | BE856784A (fr) |
| CA (1) | CA1103671A (fr) |
| CH (1) | CH625518A5 (fr) |
| DE (1) | DE2731299A1 (fr) |
| ES (2) | ES460699A1 (fr) |
| FR (1) | FR2361385A1 (fr) |
| GB (1) | GB1583753A (fr) |
| NL (1) | NL7707785A (fr) |
| OA (1) | OA05707A (fr) |
| SU (1) | SU751324A3 (fr) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3066434D1 (en) * | 1979-11-21 | 1984-03-08 | Kyowa Hakko Kogyo Kk | Novel piperidine derivatives, method for the preparation thereof and pharmaceutical compositions containing them |
| US4344945A (en) * | 1980-03-10 | 1982-08-17 | Kyowa Hakko Kogyo Co., Ltd. | Piperidine derivatives |
| US4684654A (en) * | 1985-08-14 | 1987-08-04 | American Cyanamid Company | 3-heteroalkyl-2,4-quinzaolinediones |
| PH23565A (en) * | 1986-09-05 | 1989-08-25 | Sumitomo Chemical Co | Novel pyrimidinylpyrimidine derivatives and a plant disease protectant containing them as the active ingredient |
| FI95572C (fi) * | 1987-06-22 | 1996-02-26 | Eisai Co Ltd | Menetelmä lääkeaineena käyttökelpoisen piperidiinijohdannaisten tai sen farmaseuttisen suolan valmistamiseksi |
| CA2118117A1 (fr) * | 1993-02-18 | 1994-08-19 | Shigeki Fujiwara | Inhibiteur de la capture de l'adenosine |
| JP2959765B2 (ja) * | 1997-12-12 | 1999-10-06 | 日本たばこ産業株式会社 | ３−ピペリジル−４−オキソキナゾリン誘導体及びそれを含有してなる医薬組成物 |
| US6258819B1 (en) * | 1999-08-05 | 2001-07-10 | Syntex (U.S.A.) Llc | Substituted 2(4-piperidyl)-4(3H)-quinazolinones and 2-(4-piperidyl)-4(3H)-azaquinazolinones |
| EP1717230B1 (fr) * | 2004-02-13 | 2014-08-06 | Msd K.K. | Derive de 4-oxopyrimidine cycles fusionnes |
| WO2008094909A2 (fr) * | 2007-01-29 | 2008-08-07 | Xenon Pharmaceuticals Inc. | Composés de quinazolinone et de pyrimidinone fusionnés et leur utilisation dans le traitement de maladies ou d'affections induites par les canaux sodiques |
| WO2014102592A2 (fr) | 2012-12-27 | 2014-07-03 | Purdue Pharma L.P. | Composés de pipéridine de type quinoxaline substituée par oxime et leurs utilisations |
| JO3512B1 (ar) | 2014-03-26 | 2020-07-05 | Astex Therapeutics Ltd | مشتقات كينوكسالين مفيدة كمعدلات لإنزيم fgfr كيناز |
| BR112018005637B1 (pt) | 2015-09-23 | 2023-11-28 | Janssen Pharmaceutica Nv | Compostos derivados de quinoxalina, quinolina e quinazolinona,composições farmacêuticas que os compreende, e uso dos referidos compostos |
| HUE057090T2 (hu) | 2015-09-23 | 2022-04-28 | Janssen Pharmaceutica Nv | BI-heteroaril-szubsztituált 1,4-benzodiazepinek és alkalmazásuk rák kezelésében |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2694711A (en) * | 1952-12-02 | 1954-11-16 | American Cyanamid Co | Quinazolone antimalarial compounds |
| US3086910A (en) * | 1960-03-09 | 1963-04-23 | Wallace & Tiernan Inc | Central nervous system depressants 3-(2'-pyridyl)-4-quinazolones |
| US3257397A (en) * | 1963-07-26 | 1966-06-21 | Rexall Drug Chemical | Substituted 2, 3-dihydro-4(1h)-quinazolinones |
| US4027028A (en) * | 1975-11-10 | 1977-05-31 | Science Union Et Cie | Arylethers and pharmaceutical compositions |
-
1976
- 1976-07-14 GB GB29317/76A patent/GB1583753A/en not_active Expired
-
1977
- 1977-07-08 FR FR7721035A patent/FR2361385A1/fr active Granted
- 1977-07-11 US US05/814,482 patent/US4166117A/en not_active Expired - Lifetime
- 1977-07-11 DE DE19772731299 patent/DE2731299A1/de not_active Withdrawn
- 1977-07-12 OA OA56223A patent/OA05707A/fr unknown
- 1977-07-13 JP JP8402477A patent/JPS5334784A/ja active Pending
- 1977-07-13 CA CA282,619A patent/CA1103671A/fr not_active Expired
- 1977-07-13 ES ES460699A patent/ES460699A1/es not_active Expired
- 1977-07-13 NL NL7707785A patent/NL7707785A/xx not_active Application Discontinuation
- 1977-07-13 BE BE179318A patent/BE856784A/fr unknown
- 1977-07-14 CH CH872877A patent/CH625518A5/fr not_active IP Right Cessation
-
1978
- 1978-08-14 ES ES472563A patent/ES472563A1/es not_active Expired
- 1978-10-17 SU SU782674601A patent/SU751324A3/ru active
Also Published As
| Publication number | Publication date |
|---|---|
| GB1583753A (en) | 1981-02-04 |
| ES460699A1 (es) | 1978-12-01 |
| BE856784A (fr) | 1978-01-13 |
| SU751324A3 (ru) | 1980-07-23 |
| CH625518A5 (fr) | 1981-09-30 |
| NL7707785A (nl) | 1978-01-17 |
| CA1103671A (fr) | 1981-06-23 |
| US4166117A (en) | 1979-08-28 |
| DE2731299A1 (de) | 1978-01-19 |
| JPS5334784A (en) | 1978-03-31 |
| ES472563A1 (es) | 1979-10-16 |
| FR2361385B1 (fr) | 1983-10-07 |
| FR2361385A1 (fr) | 1978-03-10 |
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