NZ598783A - Use of opioid receptor antagonist for gastrointestinal tract disorders - Google Patents

Use of opioid receptor antagonist for gastrointestinal tract disorders

Info

Publication number
NZ598783A
NZ598783A NZ598783A NZ59878310A NZ598783A NZ 598783 A NZ598783 A NZ 598783A NZ 598783 A NZ598783 A NZ 598783A NZ 59878310 A NZ59878310 A NZ 59878310A NZ 598783 A NZ598783 A NZ 598783A
Authority
NZ
New Zealand
Prior art keywords
gastrointestinal tract
receptor antagonist
opioid receptor
tract disorders
opioid
Prior art date
Application number
NZ598783A
Other languages
English (en)
Inventor
Richard M Woodward
Original Assignee
Adolor Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=43216894&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NZ598783(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Adolor Corp filed Critical Adolor Corp
Publication of NZ598783A publication Critical patent/NZ598783A/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4965—Non-condensed pyrazines
    • A61K31/497—Non-condensed pyrazines containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/10—Laxatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2121/00—Preparations for use in therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Otolaryngology (AREA)
  • Pulmonology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
NZ598783A 2009-09-18 2010-09-17 Use of opioid receptor antagonist for gastrointestinal tract disorders NZ598783A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US24361609P 2009-09-18 2009-09-18
PCT/US2010/049311 WO2011035142A1 (en) 2009-09-18 2010-09-17 Use of opioid receptor antagonist for gastrointestinal tract disorders

Publications (1)

Publication Number Publication Date
NZ598783A true NZ598783A (en) 2013-07-26

Family

ID=43216894

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ598783A NZ598783A (en) 2009-09-18 2010-09-17 Use of opioid receptor antagonist for gastrointestinal tract disorders

Country Status (19)

Country Link
US (1) US20110071163A1 (enrdf_load_stackoverflow)
EP (1) EP2477627B1 (enrdf_load_stackoverflow)
JP (1) JP5797655B2 (enrdf_load_stackoverflow)
KR (1) KR20120092592A (enrdf_load_stackoverflow)
CN (2) CN104958298A (enrdf_load_stackoverflow)
AU (1) AU2010295464B2 (enrdf_load_stackoverflow)
BR (1) BR112012006069A8 (enrdf_load_stackoverflow)
CA (1) CA2774021A1 (enrdf_load_stackoverflow)
CL (1) CL2012000676A1 (enrdf_load_stackoverflow)
CO (1) CO6531453A2 (enrdf_load_stackoverflow)
HK (1) HK1210959A1 (enrdf_load_stackoverflow)
IL (1) IL218679A0 (enrdf_load_stackoverflow)
MX (1) MX342548B (enrdf_load_stackoverflow)
NZ (1) NZ598783A (enrdf_load_stackoverflow)
PE (1) PE20120991A1 (enrdf_load_stackoverflow)
RU (1) RU2561873C2 (enrdf_load_stackoverflow)
TW (1) TW201118084A (enrdf_load_stackoverflow)
WO (1) WO2011035142A1 (enrdf_load_stackoverflow)
ZA (1) ZA201201954B (enrdf_load_stackoverflow)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUE027856T2 (en) 2012-12-28 2016-11-28 Inst Medycyny Doswiadczalnej I Klinicznej Im Miroslawa Mossakowskiego Polskiej Akademii Nauk Peptidomimetics and their use
AU2017265377A1 (en) 2016-05-20 2018-11-22 Esteve Pharmaceuticals, S.A. Tetrahydropyran and Thiopyran derivatives having multimodal activity against pain
CN106117190B (zh) * 2016-06-21 2019-03-29 山东川成医药股份有限公司 一种倍福普兰的合成方法

Family Cites Families (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4191771A (en) * 1974-09-06 1980-03-04 Eli Lilly And Company Analgesic method using 1,3,4-trisubstituted-4-arylpiperidines
US5166174A (en) * 1987-01-28 1992-11-24 K.K. Ueno Seiyaku Oyo Kenkyujo Prostaglandins E and anti-ulcers containing same
US4891379A (en) * 1987-04-16 1990-01-02 Kabushiki Kaisha Kobe Seikosho Piperidine opioid antagonists
US5319087A (en) * 1987-04-16 1994-06-07 Eli Lilly And Company Piperidine opioid antagonists
US5064834A (en) * 1987-04-16 1991-11-12 Eli Lilly And Company Piperidine opioid antagonists
US4992450A (en) * 1987-04-16 1991-02-12 Eli Lilly And Company Piperidine opioid antagonists
US5250542A (en) * 1991-03-29 1993-10-05 Eli Lilly And Company Peripherally selective piperidine carboxylate opioid antagonists
US5270328A (en) * 1991-03-29 1993-12-14 Eli Lilly And Company Peripherally selective piperidine opioid antagonists
US5159081A (en) * 1991-03-29 1992-10-27 Eli Lilly And Company Intermediates of peripherally selective n-carbonyl-3,4,4-trisubstituted piperidine opioid antagonists
US5698155A (en) 1991-05-31 1997-12-16 Gs Technologies, Inc. Method for the manufacture of pharmaceutical cellulose capsules
AU689250B2 (en) 1994-04-22 1998-03-26 Astellas Pharma Inc. Colon-specific drug release system
US5378448A (en) * 1994-06-07 1995-01-03 Lin; Hsing K. Process for removing selenium from sulfur
TW490465B (en) * 1994-11-24 2002-06-11 Janssen Pharmaceutica Nv Enterokinetic benzamide, the preparation process and the pharmaceutical compositions thereof
ES2171839T3 (es) * 1996-09-05 2002-09-16 Lilly Co Eli Analogos de carbazol como agonistas adrenergicos selectivos de beta3.
US6559158B1 (en) * 1997-11-03 2003-05-06 Ur Labs, Inc. Use of methylnaltrexone and related compounds to treat chronic opioid use side affects
US6022884A (en) * 1997-11-07 2000-02-08 Amgen Inc. Substituted pyridine compounds and methods of use
WO2000018377A1 (en) 1998-09-28 2000-04-06 Warner-Lambert Company Enteric and colonic delivery using hpmc capsules
US6436959B1 (en) * 1998-12-23 2002-08-20 Ortho-Mcneil Pharmaceutical, Inc. 4-[aryl(piperidin-4-yl)]aminobenzamides
US6194382B1 (en) * 1999-03-03 2001-02-27 Albert Einstein College Of Medicine Of Yeshiva University Method and composition for treating irritable bowel syndrome using low doses of opioid receptor antagonists
ES2309410T5 (es) * 1999-10-15 2015-03-17 Sucampo Ag Nueva composición que contiene un compuesto bi-ciclico y un glicérido
DE60013630T2 (de) * 1999-11-01 2005-09-15 John Cardiff Rhodes Arzneimittel zur behandlung von darmverstopfung und reizkolon
US6469030B2 (en) * 1999-11-29 2002-10-22 Adolor Corporation Methods for the treatment and prevention of ileus
US6414016B1 (en) * 2000-09-05 2002-07-02 Sucampo, A.G. Anti-constipation composition
DE60109960T2 (de) * 2000-10-31 2006-02-16 Rensselaer Polytechnic Institute 8-substituierte 2,6-methano-3-benzazocine und 3-substituierte morphinane als opioidrezeptorbindende agenzien
AU2002330747B2 (en) * 2001-08-31 2007-07-19 Sucampo Ag Prostaglandin analogs as chloride channel opener
EP2236161A1 (en) * 2001-10-18 2010-10-06 Nektar Therapeutics Polymer conjugates of opioid antagonists
TWI331920B (en) * 2001-11-14 2010-10-21 Sucampo Ag Unit dosage form for relieving or treating constipation in human patients
BRPI0314308B8 (pt) * 2002-09-19 2021-05-25 Lilly Co Eli antagonistas de opióide, seus usos, e composição farmacêutica
AU2003292556B2 (en) * 2002-12-27 2009-09-10 Sucampo Ag Derivatives of prostaglandins for treating abdominal discomfort
AU2004220113A1 (en) * 2003-03-07 2004-09-23 Eli Lilly And Company Opioid receptor antagonists
AU2004303790A1 (en) * 2003-12-12 2005-07-07 Eli Lilly And Company Opioid receptor antagonists
CA2549089A1 (en) * 2003-12-22 2005-07-21 Eli Lilly And Company Opioid receptor antagonists
WO2005090286A1 (en) * 2004-03-12 2005-09-29 Eli Lilly And Company Opioid receptor antagonists
US7288543B2 (en) * 2004-03-12 2007-10-30 Eli Lilly And Company Opioid receptor antagonists
US8524731B2 (en) * 2005-03-07 2013-09-03 The University Of Chicago Use of opioid antagonists to attenuate endothelial cell proliferation and migration
WO2006126529A1 (ja) * 2005-05-25 2006-11-30 Shionogi & Co., Ltd. ６，７－不飽和－７－カルバモイル置換モルヒナン誘導体
WO2007086536A2 (en) * 2006-01-24 2007-08-02 R-Tech Ueno, Ltd. Soft-gelatin capsule formulation
MY145633A (en) * 2006-03-01 2012-03-15 Theravance Inc 8-azabicyclo[3.2.1]octane compounds as mu opioid receptor antagonists
TWI409067B (zh) * 2007-02-28 2013-09-21 Theravance Inc ８-氮雜雙環〔３．２．１〕辛烷化合物之結晶型
JP2011500686A (ja) * 2007-10-18 2011-01-06 アイコ バイオテクノロジー オピオイドと中性アンタゴニストを用いる組合せ鎮痛剤
MY149973A (en) * 2007-12-11 2013-11-15 Theravance Inc 3-carboxypropyl-aminotetralin derivatives as mu opioid receptor antagonists
MY179041A (en) * 2008-12-10 2020-10-26 Theravance Biopharma R&D Ip Llc Crystalline forms of a 3-carboxypropyl-aminotetralin compound
ES2729679T3 (es) * 2009-12-04 2019-11-05 Alkermes Pharma Ireland Ltd Derivados de morfinano para el tratamiento de la sobredosis de fármacos

Also Published As

Publication number Publication date
TW201118084A (en) 2011-06-01
EP2477627A1 (en) 2012-07-25
MX342548B (es) 2016-10-04
IL218679A0 (en) 2012-05-31
AU2010295464B2 (en) 2015-11-26
HK1210959A1 (en) 2016-05-13
JP5797655B2 (ja) 2015-10-21
JP2013505260A (ja) 2013-02-14
PE20120991A1 (es) 2012-08-01
US20110071163A1 (en) 2011-03-24
RU2012115450A (ru) 2013-10-27
BR112012006069A2 (pt) 2016-03-29
MX2012003310A (es) 2012-07-17
RU2561873C2 (ru) 2015-09-10
BR112012006069A8 (pt) 2017-10-10
KR20120092592A (ko) 2012-08-21
CN104958298A (zh) 2015-10-07
CA2774021A1 (en) 2011-03-24
EP2477627B1 (en) 2018-08-15
ZA201201954B (en) 2012-11-28
WO2011035142A1 (en) 2011-03-24
CL2012000676A1 (es) 2012-10-19
AU2010295464A1 (en) 2012-04-12
CN102695508A (zh) 2012-09-26
CO6531453A2 (es) 2012-09-28

Similar Documents

Publication Publication Date Title
GEP20135744B (en) Quinuclidine carbonate derivatives and medicinal compositions containing the same
MX2009010759A (es) Derivados de carboxamida imidazolidina como modulares de p2x7.
MX2012004848A (es) Compuestos heterociclicos triciclicos.
MY152279A (en) Immediate release pharmaceutical compositions comprising oxycodone and naloxone
MX2010001236A (es) Derivados de 5-fenil-isoxazol-3-carboxamida como moduladores del receptor de potencial transitorio v1 (trpv1).
NO20085051L (no) Behandling av gastrointestinale forstyrrelser med CGRP-antagonister
NZ589733A (en) Oral administration of peripherally-acting opioid antagonists
IL193252A0 (en) N-hydroxyacrylamide compounds
TN2012000046A1 (en) Pharmaceutical compositions for the treatment of cancer and other diseases or disorfers
WO2009025785A3 (en) Cb2 receptor ligands for the treatment of pain
NZ605431A (en) D2 antagonists, methods of synthesis and methods of use
MY154591A (en) Therapeutic compositions comprising a specific endothelin receptor antagonist and a pde5 inhibitor
MY148084A (en) Substituted carboxamides as group i metabotropic receptor antagonists
MX2013006768A (es) Moduladores de receptor de glucagon.
NZ598783A (en) Use of opioid receptor antagonist for gastrointestinal tract disorders
WO2007114902A3 (en) Alkylthiobenzylpiperidine compounds
MX2012007005A (es) Tiazoles biciclicos como moduladores alostericos de recptores de glutamato metabotropico subtipo 5.
MY156278A (en) Disubstituted [4-(5-aminomethyl-phenyl)-piperidin-1-yl]-1h-indol-3-yl]-methanones
WO2011080502A3 (en) New pharmaceutical dosage form for the treatment of gastric acid-related disorders
WO2007114916A3 (en) Arylbenzylpiperidine compounds
MX2011008857A (es) Derivados de oxiindol con actividad agonistica del receptor de motilina.
MX2012007006A (es) Tiazoles biciclicos como moduladores alostericos de receptores mglur5.
GEP20125640B (en) Phenanthrenone compounds, compositions containing them and use thereof
PL1805169T3 (pl) Inhibitory receptora histaminowego H3, ich wytwarzanie i zastosowania terapeutyczne
HK1173956A (en) Use of opioid receptor antagonist for gastrointestinal tract disorders

Legal Events

Date Code Title Description
ERR Error or correction

Free format text: THE TITLE HAS BEEN CORRECTED TO TITLE: USE OF OPIOID RECEPTOR ANTAGONIST FOR GASTROINTESTINAL TRACT DISORDERS; FILING DATE: 14 MAR 2012; STATUS: REJECTED; TITLE: USE OF OPIOID RECEPTOR ANTAGONIST FOR GASTROINTESTINAL TRACT DISORDERS; FILING DATE: 13 NOV 2012; STATUS: REJECTED; TITLE: USE OF OPIOID RECEPTOR ANTAGONIST FOR GASTROINTESTINAL TRACT DISORDERS; FILING DATE: 17 JUN 2013; STATUS: REJECTED; TITLE: USE OF OPIOID RECEPTOR ANTAGONIST FOR GASTROINTESTINAL TRACT DISORDERS; FILING DATE: 17 JUN 2013; STATUS: PROPOSED;

Effective date: 20130625

PSEA Patent sealed
RENW Renewal (renewal fees accepted)

Free format text: PATENT RENEWED FOR 3 YEARS UNTIL 17 SEP 2017 BY COMPUTER PACKAGES INC

Effective date: 20140910

LAPS Patent lapsed