NZ598718A - Polymorphic forms of manidipine - Google Patents
Polymorphic forms of manidipineInfo
- Publication number
- NZ598718A NZ598718A NZ598718A NZ59871810A NZ598718A NZ 598718 A NZ598718 A NZ 598718A NZ 598718 A NZ598718 A NZ 598718A NZ 59871810 A NZ59871810 A NZ 59871810A NZ 598718 A NZ598718 A NZ 598718A
- Authority
- NZ
- New Zealand
- Prior art keywords
- manidipine
- polymorphic forms
- forms
- crystalline
- manidpine
- Prior art date
Links
- ANEBWFXPVPTEET-UHFFFAOYSA-N manidipine Chemical compound COC(=O)C1=C(C)NC(C)=C(C(=O)OCCN2CCN(CC2)C(C=2C=CC=CC=2)C=2C=CC=CC=2)C1C1=CC=CC([N+]([O-])=O)=C1 ANEBWFXPVPTEET-UHFFFAOYSA-N 0.000 title abstract 3
- 229960003963 manidipine Drugs 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
- C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN1970MU2009 | 2009-08-27 | ||
| PCT/GB2010/001615 WO2011023954A2 (en) | 2009-08-27 | 2010-08-26 | Polymorphic forms of manidipine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NZ598718A true NZ598718A (en) | 2014-10-31 |
Family
ID=43530516
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NZ598718A NZ598718A (en) | 2009-08-27 | 2010-08-26 | Polymorphic forms of manidipine |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US9018376B2 (enExample) |
| EP (1) | EP2470505A2 (enExample) |
| JP (1) | JP2013503145A (enExample) |
| KR (1) | KR20130027005A (enExample) |
| AU (1) | AU2010288273A1 (enExample) |
| CA (1) | CA2772499A1 (enExample) |
| NZ (1) | NZ598718A (enExample) |
| WO (1) | WO2011023954A2 (enExample) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2011023954A2 (en) | 2009-08-27 | 2011-03-03 | Cipla Limited | Polymorphic forms of manidipine |
| CN102875451B (zh) * | 2012-04-05 | 2014-12-03 | 常州制药厂有限公司 | 一种盐酸马尼地平合成工艺的改进方法 |
| CN103467364B (zh) * | 2013-06-21 | 2015-07-15 | 四川海思科制药有限公司 | 一种盐酸马尼地平化合物 |
| CN104292150A (zh) * | 2013-07-19 | 2015-01-21 | 许昌恒生制药有限公司 | 一种盐酸马尼地平的合成工艺 |
| CN104447513B (zh) * | 2014-11-26 | 2018-05-29 | 许昌恒生制药有限公司 | 一种高纯度盐酸马尼地平β晶型的制备方法 |
| CN108218765A (zh) * | 2017-11-24 | 2018-06-29 | 扬子江药业集团北京海燕药业有限公司 | 一种改进盐酸马尼地平ii晶型的生产方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE50987T1 (de) | 1982-05-10 | 1990-03-15 | Takeda Chemical Industries Ltd | Dihydropyridinderivate, deren herstellung und verwendung. |
| WO1983004023A1 (en) * | 1982-05-10 | 1983-11-24 | Takeda Chemical Industries, Ltd. | Dihydropyridine derivatives |
| US4994461A (en) | 1987-03-27 | 1991-02-19 | Byk Gulden Lomberg Chemische Fabrik Gmbh | 1,4-dihydropyridine enantiomers |
| ITMI20072226A1 (it) | 2007-11-23 | 2009-05-24 | Chiesi Farma Spa | Un metodo per determinare la purezza polimorfica di manidipina dicloridrato |
| WO2011023954A2 (en) | 2009-08-27 | 2011-03-03 | Cipla Limited | Polymorphic forms of manidipine |
-
2010
- 2010-08-26 WO PCT/GB2010/001615 patent/WO2011023954A2/en not_active Ceased
- 2010-08-26 US US13/392,583 patent/US9018376B2/en not_active Expired - Fee Related
- 2010-08-26 AU AU2010288273A patent/AU2010288273A1/en not_active Abandoned
- 2010-08-26 EP EP10752105A patent/EP2470505A2/en not_active Withdrawn
- 2010-08-26 JP JP2012526115A patent/JP2013503145A/ja active Pending
- 2010-08-26 NZ NZ598718A patent/NZ598718A/en not_active IP Right Cessation
- 2010-08-26 KR KR1020127007646A patent/KR20130027005A/ko not_active Ceased
- 2010-08-26 CA CA2772499A patent/CA2772499A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US9018376B2 (en) | 2015-04-28 |
| EP2470505A2 (en) | 2012-07-04 |
| WO2011023954A3 (en) | 2011-04-21 |
| AU2010288273A1 (en) | 2012-04-12 |
| KR20130027005A (ko) | 2013-03-14 |
| WO2011023954A2 (en) | 2011-03-03 |
| US20120232091A1 (en) | 2012-09-13 |
| CA2772499A1 (en) | 2011-03-03 |
| JP2013503145A (ja) | 2013-01-31 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| NZ598718A (en) | Polymorphic forms of manidipine | |
| WO2007127297A3 (en) | Crystalline forms of a dimethylphenyl compound | |
| MX2010006179A (es) | Formas solidas de acido 3-(6-(1-(2,2-difluorobenzo[d] [1,3]dioxol-5-il)ciclopropancarboxamido)-3-metilpiridin-2-il)benz oico. | |
| IL216349A (en) | Annals 4– (1-carboxy-ethylcarbamoyl) –4– (5– [1,12] diethylan-3-ram-pentanoylamino) -butyric acid and preparations containing them | |
| UA102574C2 (ru) | 1-фенил-2-пиридинилалкил-спиртовые производные как ингибиторы фосфодиэстеразы | |
| ZA200804393B (en) | Heteroaryl substituted piperidine derivatives as L-CPT1 inhibitors | |
| PE20070141A1 (es) | Derivados de isoquinolina como inhibidores de rho-cinasa | |
| WO2010067374A3 (en) | Polymorphs of dasatinib | |
| TW200613296A (en) | Crystalline form of a biphenyl compound | |
| NO20070445L (no) | Pyrimidinderivater. | |
| WO2009023539A3 (en) | Tetrahydropyridine carboxamide derivatives as trpvl antagonists | |
| WO2010001257A3 (en) | Novel solid state forms of laquinimod and its sodium salt | |
| ZA200705473B (en) | Processes for preparing 4-(phenoxy-5-methyl-pyrimidin-4-yloxy)piperidine-1-carboxylic acid derivatives and related compounds | |
| MX2011005090A (es) | Forma cristalina de un compuesto de 4-[2-(2-fluorofenoximetil)feni l] piperidina. | |
| ATE465719T1 (de) | Oral zerfallende zusammensetzung von olanzapin oder donepezil | |
| EP2865678A3 (en) | Crystalline hemi-tartrate form of a benzoimidazol-2-yl pyrimidine derivative | |
| EP3020704A3 (en) | Crystalline polymorphs of clevidipine butyrate | |
| WO2008087654A3 (en) | PIPERIDINES AS INHIBITORS OF 11β-HYDROXYSTEROID DEHYDROGENASE TYPE 1 | |
| WO2013175499A3 (en) | Process for the preparation of 5-(4-[4-(5-cyano-1 h-indol-3-yl)butyl]piperazin-1 -yl)benzofuran-2-carboxamide and intermediates thereof, polymorphic forms thereof | |
| WO2007096875A3 (en) | Novel polymorphs of montelukast ammonium salts and processes for preparation therefor | |
| WO2010036640A3 (en) | Compounds for the treatment of inflammatory disorders | |
| WO2009021943A3 (de) | Neues herstellverfahren | |
| TW200736245A (en) | Acid addition salts of optically active dihydropyridine derivatives | |
| EP1577309A4 (en) | Optically active dihydropyridine derivative | |
| WO2011161245A3 (en) | Polymorphs of febuxostat |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| AABA | Application abandoned | ||
| PSEA | Patent sealed | ||
| RENW | Renewal (renewal fees accepted) |
Free format text: PATENT RENEWED FOR 3 YEARS UNTIL 26 AUG 2017 BY BALDWINS INTELLECTUAL PROPERTY Effective date: 20150330 |
|
| LAPS | Patent lapsed |