NZ598031A - Inhibition of the tumorigenic potential of tumor stem cells by lif and bmps - Google Patents

Inhibition of the tumorigenic potential of tumor stem cells by lif and bmps

Info

Publication number
NZ598031A
NZ598031A NZ598031A NZ59803106A NZ598031A NZ 598031 A NZ598031 A NZ 598031A NZ 598031 A NZ598031 A NZ 598031A NZ 59803106 A NZ59803106 A NZ 59803106A NZ 598031 A NZ598031 A NZ 598031A
Authority
NZ
New Zealand
Prior art keywords
lif
tumor stem
targeted
bmps
inhibition
Prior art date
Application number
NZ598031A
Other languages
English (en)
Inventor
Angelo Luigi Vescovi
Brent Allan Reynolds
Original Assignee
Stemgen S P A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Stemgen S P A filed Critical Stemgen S P A
Publication of NZ598031A publication Critical patent/NZ598031A/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/20—Interleukins [IL]
    • A61K38/2093—Leukaemia inhibitory factor [LIF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A61K38/1875—Bone morphogenic factor; Osteogenins; Osteogenic factor; Bone-inducing factor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
NZ598031A 2005-07-19 2006-07-19 Inhibition of the tumorigenic potential of tumor stem cells by lif and bmps NZ598031A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US70085905P 2005-07-19 2005-07-19
NZ565172A NZ565172A (en) 2005-07-19 2006-07-19 Inhibition of the tumorigenic potential of tumor stem cells by LIF and BMPS

Publications (1)

Publication Number Publication Date
NZ598031A true NZ598031A (en) 2013-11-29

Family

ID=37420973

Family Applications (2)

Application Number Title Priority Date Filing Date
NZ598031A NZ598031A (en) 2005-07-19 2006-07-19 Inhibition of the tumorigenic potential of tumor stem cells by lif and bmps
NZ565172A NZ565172A (en) 2005-07-19 2006-07-19 Inhibition of the tumorigenic potential of tumor stem cells by LIF and BMPS

Family Applications After (1)

Application Number Title Priority Date Filing Date
NZ565172A NZ565172A (en) 2005-07-19 2006-07-19 Inhibition of the tumorigenic potential of tumor stem cells by LIF and BMPS

Country Status (13)

Country Link
US (2) US9220756B2 (cg-RX-API-DMAC7.html)
EP (2) EP3117833B1 (cg-RX-API-DMAC7.html)
JP (3) JP5189977B2 (cg-RX-API-DMAC7.html)
KR (2) KR101311061B1 (cg-RX-API-DMAC7.html)
AU (1) AU2006271308B2 (cg-RX-API-DMAC7.html)
CA (2) CA2615491C (cg-RX-API-DMAC7.html)
DK (2) DK1904093T3 (cg-RX-API-DMAC7.html)
ES (2) ES2686093T3 (cg-RX-API-DMAC7.html)
HR (1) HRP20181379T1 (cg-RX-API-DMAC7.html)
HU (2) HUE040063T2 (cg-RX-API-DMAC7.html)
NZ (2) NZ598031A (cg-RX-API-DMAC7.html)
PL (2) PL3117833T3 (cg-RX-API-DMAC7.html)
WO (1) WO2007010394A2 (cg-RX-API-DMAC7.html)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007010394A2 (en) * 2005-07-19 2007-01-25 Stemgen S.P.A. Inhibition of the tumorigenic potential of tumor stem cells by lif and bmps
ATE526984T1 (de) 2008-02-13 2011-10-15 Dkfz Krebsforschungszentrum Knochen-morphogenetische proteine zur verwendung zur behandlung und prävention von neuroblastomen
JP7056932B2 (ja) 2015-08-25 2022-04-19 ヒスタイド アクツィエンゲゼルシャフト 組織形成誘導用化合物及びその使用
AU2016324971A1 (en) * 2015-09-17 2018-04-19 Histide Ag Pharmaceutical association comprising a growth factor receptor agonist conjugated to a bioactive carrierfor converting a neoplastic cell into a non-neoplastic cell and uses thereof
HRP20211627T1 (hr) * 2015-09-17 2022-02-04 Histide Ag Farmaceutski pripravak koji se sastoji od agonista receptora čimbenika rasta i proteina inhibitora adhezije za pretvaranje neoplastične stanice u neneoplastičnu stanicu i njegova upotreba
WO2017046226A2 (en) * 2015-09-17 2017-03-23 Histide Ag Pharmaceutical association for converting a neoplastic cell into a non-neoplastic cell and uses thereof.
KR20180050744A (ko) * 2015-09-17 2018-05-23 히스티드 아게 신생물성 세포를 비-신생물성 세포로 전환시키기 위한 약제학적 회합물 및 이것의 용도
JP6890835B2 (ja) * 2015-09-17 2021-06-18 ヒスタイド アクツィエンゲゼルシャフト 腫瘍細胞を非腫瘍細胞に変換するための医薬的連合体及びその使用
WO2020138503A1 (ja) * 2018-12-28 2020-07-02 国立大学法人 東京大学 神経膠腫の治療および予防剤、脳腫瘍の悪性度のマーカーおよび脳腫瘍の予後マーカー、脳腫瘍の悪性度および予後の判定方法並びに腫瘍増殖を抑制する抗体

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Also Published As

Publication number Publication date
CA2790675A1 (en) 2007-01-25
PL3117833T3 (pl) 2019-06-28
HRP20181379T1 (hr) 2018-11-16
WO2007010394A2 (en) 2007-01-25
ES2686093T3 (es) 2018-10-16
HUE042197T2 (hu) 2019-06-28
JP5891068B2 (ja) 2016-03-22
KR101311061B1 (ko) 2013-09-25
EP3117833B1 (en) 2019-01-23
JP5189977B2 (ja) 2013-04-24
US9220756B2 (en) 2015-12-29
ES2710601T3 (es) 2019-04-26
US20100167999A1 (en) 2010-07-01
JP2012107063A (ja) 2012-06-07
US9737589B2 (en) 2017-08-22
KR20120125990A (ko) 2012-11-19
EP1904093B1 (en) 2018-06-13
EP1904093A2 (en) 2008-04-02
DK3117833T3 (en) 2019-03-18
PL1904093T3 (pl) 2018-12-31
US20160228511A1 (en) 2016-08-11
AU2006271308B2 (en) 2012-12-20
HUE040063T2 (hu) 2019-02-28
JP2015057452A (ja) 2015-03-26
DK1904093T3 (en) 2018-09-03
KR101338533B1 (ko) 2013-12-12
CA2615491C (en) 2016-11-29
CA2615491A1 (en) 2007-01-25
KR20080082595A (ko) 2008-09-11
JP2009502771A (ja) 2009-01-29
WO2007010394A3 (en) 2007-08-30
CA2790675C (en) 2016-12-20
AU2006271308A1 (en) 2007-01-25
EP3117833A1 (en) 2017-01-18
NZ565172A (en) 2012-12-21

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