NZ576174A - Novel antiproliferation antibodies - Google Patents

Novel antiproliferation antibodies

Info

Publication number
NZ576174A
NZ576174A NZ576174A NZ57617407A NZ576174A NZ 576174 A NZ576174 A NZ 576174A NZ 576174 A NZ576174 A NZ 576174A NZ 57617407 A NZ57617407 A NZ 57617407A NZ 576174 A NZ576174 A NZ 576174A
Authority
NZ
New Zealand
Prior art keywords
antibody
cdr
sequence seq
same
functional fragment
Prior art date
Application number
NZ576174A
Other languages
English (en)
Inventor
Liliane Goetsch
Nathalie Corvaia
Jean-Francois Haeuw
Cedric Bes
Original Assignee
Pf Medicament
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pf Medicament filed Critical Pf Medicament
Publication of NZ576174A publication Critical patent/NZ576174A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10Cells modified by introduction of foreign genetic material
    • C12N5/12Fused cells, e.g. hybridomas
    • C12N5/16Animal cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/54F(ab')2
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Oncology (AREA)
  • General Engineering & Computer Science (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
NZ576174A 2006-11-24 2007-11-23 Novel antiproliferation antibodies NZ576174A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0610329A FR2909092B1 (fr) 2006-11-24 2006-11-24 Nouveaux anticorps anti-proliferation
PCT/EP2007/062760 WO2008062063A1 (en) 2006-11-24 2007-11-23 Novel antiproliferation antibodies

Publications (1)

Publication Number Publication Date
NZ576174A true NZ576174A (en) 2012-03-30

Family

ID=37903981

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ576174A NZ576174A (en) 2006-11-24 2007-11-23 Novel antiproliferation antibodies

Country Status (27)

Country Link
US (2) US8071730B2 (cg-RX-API-DMAC7.html)
EP (1) EP2074148A1 (cg-RX-API-DMAC7.html)
JP (1) JP2010509931A (cg-RX-API-DMAC7.html)
KR (1) KR20090088878A (cg-RX-API-DMAC7.html)
CN (1) CN101535344B (cg-RX-API-DMAC7.html)
AU (1) AU2007324509B2 (cg-RX-API-DMAC7.html)
BR (1) BRPI0719323A2 (cg-RX-API-DMAC7.html)
CA (1) CA2670039A1 (cg-RX-API-DMAC7.html)
CL (1) CL2007003357A1 (cg-RX-API-DMAC7.html)
CR (1) CR10788A (cg-RX-API-DMAC7.html)
CU (1) CU23792A3 (cg-RX-API-DMAC7.html)
EC (1) ECSP099341A (cg-RX-API-DMAC7.html)
FR (1) FR2909092B1 (cg-RX-API-DMAC7.html)
GE (1) GEP20125629B (cg-RX-API-DMAC7.html)
GT (1) GT200900126A (cg-RX-API-DMAC7.html)
IL (1) IL198744A0 (cg-RX-API-DMAC7.html)
MA (1) MA30891B1 (cg-RX-API-DMAC7.html)
MX (1) MX2009005293A (cg-RX-API-DMAC7.html)
NI (1) NI200900079A (cg-RX-API-DMAC7.html)
NO (1) NO20092360L (cg-RX-API-DMAC7.html)
NZ (1) NZ576174A (cg-RX-API-DMAC7.html)
RU (1) RU2451689C2 (cg-RX-API-DMAC7.html)
SA (1) SA07280637B1 (cg-RX-API-DMAC7.html)
TN (1) TN2009000194A1 (cg-RX-API-DMAC7.html)
TW (1) TW200829602A (cg-RX-API-DMAC7.html)
UA (1) UA99602C2 (cg-RX-API-DMAC7.html)
WO (1) WO2008062063A1 (cg-RX-API-DMAC7.html)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JOP20080381B1 (ar) 2007-08-23 2023-03-28 Amgen Inc بروتينات مرتبطة بمولدات مضادات تتفاعل مع بروبروتين كونفيرتاز سيتيليزين ككسين من النوع 9 (pcsk9)
EP2313435A4 (en) * 2008-07-01 2012-08-08 Aveo Pharmaceuticals Inc FIBROBLAST GROWTH FACTOR RECEPTOR 3 (FGFR3) BINDING PROTEINS
WO2011053759A1 (en) * 2009-10-30 2011-05-05 Merck Sharp & Dohme Corp. Ax1 and ax189 pcsk9 antagonists and variants
CN103298489A (zh) * 2010-10-29 2013-09-11 伊缪诺金公司 新型egfr结合分子及其免疫偶联物
EP2455403A1 (en) 2010-11-23 2012-05-23 Pierre Fabre Medicament Homogeneous humanized antibodies against JAM-A that inhibit proliferation
US20130287790A1 (en) * 2012-03-30 2013-10-31 The Board Of Trustees Of The Leland Standford Junior University Use of jam-a in diagnosing and treating leukemia
DK3489261T3 (da) 2012-08-24 2020-12-14 Univ California Antistoffer og vacciner til anvendelse ved behandling af ror1-cancere og hæmning af metastase
KR20150097304A (ko) 2014-02-18 2015-08-26 삼성전자주식회사 항 EGFR DARPin을 포함하는 EGFR/HER2 이중 특이 항체
CA3015619A1 (en) 2016-03-01 2017-09-08 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Antibodies specific to human poliovirus receptor (pvr)
JP7109007B2 (ja) 2016-06-27 2022-07-29 ザ・リージエンツ・オブ・ザ・ユニバーシテイー・オブ・カリフオルニア がん治療の組み合わせ
WO2018027039A1 (en) 2016-08-03 2018-02-08 Nextcure, Inc. Compositions and methods for modulating lair signal transduction
CN109022366A (zh) * 2018-08-16 2018-12-18 江南大学 一株分泌抗左旋咪唑单克隆抗体的杂交瘤细胞株及其应用
CN114740108B (zh) * 2022-03-28 2023-07-14 天津键凯科技有限公司 一种聚合物修饰抗体类药物的修饰度的测定方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9604470D0 (sv) * 1996-12-04 1996-12-04 Tamas Bartfai Konsulting Ab Transmembrane component of tight junction
US6235883B1 (en) * 1997-05-05 2001-05-22 Abgenix, Inc. Human monoclonal antibodies to epidermal growth factor receptor
US20030171568A1 (en) * 1998-09-16 2003-09-11 Avi Ashkenazi Use of A33 antigens and JAM-IT
SK14812000A3 (sk) * 1998-04-03 2001-08-06 Chugai Seiyaku Kabushiki Kaisha Chimérny reťazec protilátky, chimérna protilátka, v oblasť, humanizovaný reťazec protilátky, humanizovaná protilátka, dna, expresný vektor, hostiteľ, spôsob prípravy a liečivo
HU229376B1 (en) * 1999-03-11 2013-11-28 Serono Lab Vascular adhesion molecules and modulation of their function
WO2005060457A2 (en) * 2003-12-04 2005-07-07 Pdl Biopharma, Inc. Treatment of inflammatory bowel diseases with anti-ip-10 antibodies
WO2006008076A2 (en) * 2004-07-16 2006-01-26 Universita Degli Studi Di Milano Methods and agents stimulating the immune response
JP2008539693A (ja) * 2005-05-12 2008-11-20 オンコセラピー・サイエンス株式会社 抗dsc2抗体のエフェクター機能を用いて細胞を障害する方法
CA2650380A1 (en) * 2006-04-28 2007-11-08 Oregon Health & Science University Monoclonal antibodies and their use

Also Published As

Publication number Publication date
GT200900126A (es) 2011-09-02
BRPI0719323A2 (pt) 2014-02-04
CN101535344B (zh) 2013-10-16
RU2451689C2 (ru) 2012-05-27
EP2074148A1 (en) 2009-07-01
CA2670039A1 (en) 2008-05-29
FR2909092A1 (fr) 2008-05-30
US20120156191A1 (en) 2012-06-21
AU2007324509A1 (en) 2008-05-29
IL198744A0 (en) 2010-02-17
UA99602C2 (ru) 2012-09-10
CR10788A (es) 2009-06-23
MA30891B1 (fr) 2009-11-02
CL2007003357A1 (es) 2008-04-04
RU2009123409A (ru) 2010-12-27
FR2909092B1 (fr) 2012-10-19
TN2009000194A1 (en) 2010-10-18
MX2009005293A (es) 2009-08-07
WO2008062063A1 (en) 2008-05-29
CN101535344A (zh) 2009-09-16
GEP20125629B (en) 2012-09-10
US8071730B2 (en) 2011-12-06
US20100092455A1 (en) 2010-04-15
ECSP099341A (es) 2009-06-30
JP2010509931A (ja) 2010-04-02
AU2007324509B2 (en) 2013-01-17
NO20092360L (no) 2009-08-11
CU23792A3 (es) 2012-03-15
KR20090088878A (ko) 2009-08-20
HK1132752A1 (en) 2010-03-05
NI200900079A (es) 2010-11-10
TW200829602A (en) 2008-07-16
SA07280637B1 (ar) 2012-04-11

Similar Documents

Publication Publication Date Title
AU2007324509B2 (en) Novel antiproliferation antibodies
CN102209730B (zh) 抗cxcr4抗体及其用于治疗癌症的用途
EP2535356B1 (en) Novel antibodies inhibiting C-MET dimerization, and uses thereof
EP3431502B1 (en) Anti-cmet antibody
CA2801264C (en) Novel anti-cmet antibody
HK1132752B (en) Novel antiproliferation antibodies
HK1163119B (en) Anti cxcr4 antibodies and their use for the treatment of cancer
AU2014200629A1 (en) Novel antibodies inhibiting c-met dimerization, and uses thereof

Legal Events

Date Code Title Description
PSEA Patent sealed
RENW Renewal (renewal fees accepted)

Free format text: PATENT RENEWED FOR 1 YEAR UNTIL 23 NOV 2015 BY ACUMASS

Effective date: 20141018

LAPS Patent lapsed