NZ572525A - Detection method for influenza viruses - Google Patents
Detection method for influenza virusesInfo
- Publication number
- NZ572525A NZ572525A NZ572525A NZ57252507A NZ572525A NZ 572525 A NZ572525 A NZ 572525A NZ 572525 A NZ572525 A NZ 572525A NZ 57252507 A NZ57252507 A NZ 57252507A NZ 572525 A NZ572525 A NZ 572525A
- Authority
- NZ
- New Zealand
- Prior art keywords
- virus particles
- viruses
- virus
- detection
- influenza
- Prior art date
Links
- 238000001514 detection method Methods 0.000 title claims abstract description 61
- 241000712461 unidentified influenza virus Species 0.000 title claims abstract description 39
- 241000700605 Viruses Species 0.000 claims abstract description 102
- 238000000034 method Methods 0.000 claims abstract description 44
- 239000002245 particle Substances 0.000 claims abstract description 44
- 108010006232 Neuraminidase Proteins 0.000 claims abstract description 36
- 102000005348 Neuraminidase Human genes 0.000 claims abstract description 35
- 101710154606 Hemagglutinin Proteins 0.000 claims abstract description 21
- 101710093908 Outer capsid protein VP4 Proteins 0.000 claims abstract description 21
- 101710135467 Outer capsid protein sigma-1 Proteins 0.000 claims abstract description 21
- 101710176177 Protein A56 Proteins 0.000 claims abstract description 21
- 239000000185 hemagglutinin Substances 0.000 claims abstract description 21
- 239000000758 substrate Substances 0.000 claims abstract description 18
- 102000004190 Enzymes Human genes 0.000 claims abstract description 15
- 108090000790 Enzymes Proteins 0.000 claims abstract description 15
- 108090000288 Glycoproteins Proteins 0.000 claims abstract description 11
- 102000003886 Glycoproteins Human genes 0.000 claims abstract description 11
- 230000027455 binding Effects 0.000 claims abstract description 11
- 239000000203 mixture Substances 0.000 claims abstract description 8
- 229920001542 oligosaccharide Polymers 0.000 claims abstract description 5
- 150000002482 oligosaccharides Chemical class 0.000 claims abstract description 5
- 238000012360 testing method Methods 0.000 claims description 22
- 206010064097 avian influenza Diseases 0.000 claims description 12
- 208000002979 Influenza in Birds Diseases 0.000 claims description 10
- 238000006243 chemical reaction Methods 0.000 claims description 9
- 230000001717 pathogenic effect Effects 0.000 claims description 8
- 238000013459 approach Methods 0.000 claims description 7
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- 241001465754 Metazoa Species 0.000 claims description 5
- -1 a2-macroglobulin Proteins 0.000 claims description 5
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- 108010064983 Ovomucin Proteins 0.000 claims description 4
- 239000002253 acid Substances 0.000 claims description 4
- 230000010460 detection of virus Effects 0.000 claims description 3
- 230000007613 environmental effect Effects 0.000 claims description 3
- 239000013641 positive control Substances 0.000 claims description 3
- 239000011230 binding agent Substances 0.000 claims description 2
- 239000008280 blood Substances 0.000 claims description 2
- 210000004369 blood Anatomy 0.000 claims description 2
- 230000008859 change Effects 0.000 claims description 2
- 229920003023 plastic Polymers 0.000 claims description 2
- SQVRNKJHWKZAKO-PFQGKNLYSA-N N-acetyl-beta-neuraminic acid Chemical class CC(=O)N[C@@H]1[C@@H](O)C[C@@](O)(C(O)=O)O[C@H]1[C@H](O)[C@H](O)CO SQVRNKJHWKZAKO-PFQGKNLYSA-N 0.000 claims 2
- 238000003757 reverse transcription PCR Methods 0.000 claims 1
- 239000000523 sample Substances 0.000 description 26
- 239000000872 buffer Substances 0.000 description 25
- 102000005962 receptors Human genes 0.000 description 15
- 108020003175 receptors Proteins 0.000 description 15
- 235000014633 carbohydrates Nutrition 0.000 description 13
- 206010022000 influenza Diseases 0.000 description 12
- 241000287828 Gallus gallus Species 0.000 description 9
- 239000000243 solution Substances 0.000 description 9
- 241000271566 Aves Species 0.000 description 7
- IAZDPXIOMUYVGZ-UHFFFAOYSA-N Dimethylsulphoxide Chemical compound CS(C)=O IAZDPXIOMUYVGZ-UHFFFAOYSA-N 0.000 description 6
- 241000272525 Anas platyrhynchos Species 0.000 description 5
- 238000003556 assay Methods 0.000 description 5
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- 235000006576 Althaea officinalis Nutrition 0.000 description 4
- 102000013361 fetuin Human genes 0.000 description 4
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- 210000004072 lung Anatomy 0.000 description 3
- 235000010486 polyoxyethylene sorbitan monolaurate Nutrition 0.000 description 3
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- 238000002360 preparation method Methods 0.000 description 3
- HZAXFHJVJLSVMW-UHFFFAOYSA-N 2-Aminoethan-1-ol Chemical compound NCCO HZAXFHJVJLSVMW-UHFFFAOYSA-N 0.000 description 2
- RGSFGYAAUTVSQA-UHFFFAOYSA-N Cyclopentane Chemical compound C1CCCC1 RGSFGYAAUTVSQA-UHFFFAOYSA-N 0.000 description 2
- 241000712431 Influenza A virus Species 0.000 description 2
- JGFZNNIVVJXRND-UHFFFAOYSA-N N,N-Diisopropylethylamine (DIPEA) Chemical compound CCN(C(C)C)C(C)C JGFZNNIVVJXRND-UHFFFAOYSA-N 0.000 description 2
- 239000002250 absorbent Substances 0.000 description 2
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- 230000035931 haemagglutination Effects 0.000 description 2
- 239000003112 inhibitor Substances 0.000 description 2
- BQINXKOTJQCISL-GRCPKETISA-N keto-neuraminic acid Chemical compound OC(=O)C(=O)C[C@H](O)[C@@H](N)[C@@H](O)[C@H](O)[C@H](O)CO BQINXKOTJQCISL-GRCPKETISA-N 0.000 description 2
- CERZMXAJYMMUDR-UHFFFAOYSA-N neuraminic acid Natural products NC1C(O)CC(O)(C(O)=O)OC1C(O)C(O)CO CERZMXAJYMMUDR-UHFFFAOYSA-N 0.000 description 2
- 108090000623 proteins and genes Proteins 0.000 description 2
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- 230000003612 virological effect Effects 0.000 description 2
- 239000011534 wash buffer Substances 0.000 description 2
- 238000005406 washing Methods 0.000 description 2
- VHUUQVKOLVNVRT-UHFFFAOYSA-N Ammonium hydroxide Chemical compound [NH4+].[OH-] VHUUQVKOLVNVRT-UHFFFAOYSA-N 0.000 description 1
- 241001136800 Anas acuta Species 0.000 description 1
- LOYTUFQOTJYLPX-UHFFFAOYSA-N C1=CC=[Si]C=C1 Chemical compound C1=CC=[Si]C=C1 LOYTUFQOTJYLPX-UHFFFAOYSA-N 0.000 description 1
- 206010014612 Encephalitis viral Diseases 0.000 description 1
- 241001500351 Influenzavirus A Species 0.000 description 1
- 241000272168 Laridae Species 0.000 description 1
- 241000124008 Mammalia Species 0.000 description 1
- NQTADLQHYWFPDB-UHFFFAOYSA-N N-Hydroxysuccinimide Chemical compound ON1C(=O)CCC1=O NQTADLQHYWFPDB-UHFFFAOYSA-N 0.000 description 1
- 125000003047 N-acetyl group Chemical group 0.000 description 1
- 239000000020 Nitrocellulose Substances 0.000 description 1
- 241000712464 Orthomyxoviridae Species 0.000 description 1
- 229920002684 Sepharose Polymers 0.000 description 1
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 1
- 229920002125 Sokalan® Polymers 0.000 description 1
- 230000004520 agglutination Effects 0.000 description 1
- QGZKDVFQNNGYKY-UHFFFAOYSA-N ammonia Natural products N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 description 1
- 238000004458 analytical method Methods 0.000 description 1
- 230000000890 antigenic effect Effects 0.000 description 1
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- 230000005540 biological transmission Effects 0.000 description 1
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- 125000002433 cyclopentenyl group Chemical class C1(=CCCC1)* 0.000 description 1
- 230000034994 death Effects 0.000 description 1
- 231100000517 death Toxicity 0.000 description 1
- 230000029087 digestion Effects 0.000 description 1
- LOKCTEFSRHRXRJ-UHFFFAOYSA-I dipotassium trisodium dihydrogen phosphate hydrogen phosphate dichloride Chemical compound P(=O)(O)(O)[O-].[K+].P(=O)(O)([O-])[O-].[Na+].[Na+].[Cl-].[K+].[Cl-].[Na+] LOKCTEFSRHRXRJ-UHFFFAOYSA-I 0.000 description 1
- 235000013601 eggs Nutrition 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
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- 238000005227 gel permeation chromatography Methods 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- DMEGYFMYUHOHGS-UHFFFAOYSA-N heptamethylene Natural products C1CCCCCC1 DMEGYFMYUHOHGS-UHFFFAOYSA-N 0.000 description 1
- 230000001900 immune effect Effects 0.000 description 1
- 238000010324 immunological assay Methods 0.000 description 1
- 230000002458 infectious effect Effects 0.000 description 1
- 208000037797 influenza A Diseases 0.000 description 1
- 238000011005 laboratory method Methods 0.000 description 1
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- 239000003550 marker Substances 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
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- 239000002953 phosphate buffered saline Substances 0.000 description 1
- 229920002401 polyacrylamide Polymers 0.000 description 1
- 239000004584 polyacrylic acid Substances 0.000 description 1
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- 238000003752 polymerase chain reaction Methods 0.000 description 1
- 230000002035 prolonged effect Effects 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 238000013102 re-test Methods 0.000 description 1
- 230000004044 response Effects 0.000 description 1
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- 125000005630 sialyl group Chemical group 0.000 description 1
- 239000011780 sodium chloride Substances 0.000 description 1
- 238000011895 specific detection Methods 0.000 description 1
- 238000003786 synthesis reaction Methods 0.000 description 1
- 238000013518 transcription Methods 0.000 description 1
- 230000035897 transcription Effects 0.000 description 1
- 238000012546 transfer Methods 0.000 description 1
- 150000004043 trisaccharides Chemical class 0.000 description 1
- 229960005486 vaccine Drugs 0.000 description 1
- 201000002498 viral encephalitis Diseases 0.000 description 1
- 230000029812 viral genome replication Effects 0.000 description 1
- 210000002845 virion Anatomy 0.000 description 1
- 230000000007 visual effect Effects 0.000 description 1
Landscapes
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP06114170 | 2006-05-18 | ||
| US83941506P | 2006-08-23 | 2006-08-23 | |
| EP06119398 | 2006-08-23 | ||
| PCT/EP2007/054835 WO2007135099A1 (en) | 2006-05-18 | 2007-05-18 | Detection method for influenza viruses |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NZ572525A true NZ572525A (en) | 2010-09-30 |
Family
ID=42561294
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NZ572525A NZ572525A (en) | 2006-05-18 | 2007-05-18 | Detection method for influenza viruses |
Country Status (5)
| Country | Link |
|---|---|
| BR (1) | BRPI0712023A2 (da) |
| DK (1) | DK2018564T3 (da) |
| ES (1) | ES2345790T3 (da) |
| MY (1) | MY148949A (da) |
| NZ (1) | NZ572525A (da) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2019182466A1 (ru) * | 2018-03-21 | 2019-09-26 | Общество с ограниченной ответственностью "Синтавр" | Метод специфического выявления вируса гриппа человека |
-
2007
- 2007-05-18 MY MYPI20084611 patent/MY148949A/en unknown
- 2007-05-18 BR BRPI0712023-0A patent/BRPI0712023A2/pt not_active IP Right Cessation
- 2007-05-18 NZ NZ572525A patent/NZ572525A/en unknown
- 2007-05-18 ES ES07729279T patent/ES2345790T3/es active Active
- 2007-05-18 DK DK07729279.5T patent/DK2018564T3/da active
Also Published As
| Publication number | Publication date |
|---|---|
| ES2345790T3 (es) | 2010-10-01 |
| BRPI0712023A2 (pt) | 2011-12-27 |
| MY148949A (en) | 2013-06-14 |
| DK2018564T3 (da) | 2010-08-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PSEA | Patent sealed |