NZ561374A - Polymyxin B analogs for LPS detoxification - Google Patents

Polymyxin B analogs for LPS detoxification

Info

Publication number
NZ561374A
NZ561374A NZ561374A NZ56137406A NZ561374A NZ 561374 A NZ561374 A NZ 561374A NZ 561374 A NZ561374 A NZ 561374A NZ 56137406 A NZ56137406 A NZ 56137406A NZ 561374 A NZ561374 A NZ 561374A
Authority
NZ
New Zealand
Prior art keywords
peptide
lps
leu
cys2
saep
Prior art date
Application number
NZ561374A
Other languages
English (en)
Inventor
Massimo Porro
Tino Krell
Noelle Mistretta
Monique Moreau
Alessandro Rustici
Massimo Velucchi
Original Assignee
Sanofi Pasteur
Biosynth
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from EP05300270A external-priority patent/EP1712559A1/en
Application filed by Sanofi Pasteur, Biosynth filed Critical Sanofi Pasteur
Publication of NZ561374A publication Critical patent/NZ561374A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/06Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00General protective or antinoxious agents
    • A61P39/02Antidotes
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Veterinary Medicine (AREA)
  • Genetics & Genomics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Epidemiology (AREA)
  • Toxicology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
NZ561374A 2005-04-11 2006-04-10 Polymyxin B analogs for LPS detoxification NZ561374A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP05300270A EP1712559A1 (en) 2005-04-11 2005-04-11 Polymyxin B analogs for LPS detoxification
EP05300319 2005-04-26
PCT/EP2006/003237 WO2006108586A2 (en) 2005-04-11 2006-04-10 Polymyxin b analogs for lps detoxification

Publications (1)

Publication Number Publication Date
NZ561374A true NZ561374A (en) 2009-02-28

Family

ID=36968822

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ561374A NZ561374A (en) 2005-04-11 2006-04-10 Polymyxin B analogs for LPS detoxification

Country Status (11)

Country Link
EP (1) EP1871787A2 (pt)
JP (1) JP2008537749A (pt)
KR (1) KR20070118646A (pt)
AU (1) AU2006233634A1 (pt)
BR (1) BRPI0610701A2 (pt)
CA (1) CA2603850A1 (pt)
IL (1) IL186322A0 (pt)
MX (1) MX2007012457A (pt)
NO (1) NO20075753L (pt)
NZ (1) NZ561374A (pt)
WO (1) WO2006108586A2 (pt)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2032161B1 (en) 2006-06-12 2012-07-11 GlaxoSmithKline Biologicals S.A. L3v los vaccines
CA2761924C (fr) 2009-05-14 2017-10-31 Sanofi Pasteur Vaccin meningocoque a base de lipooligosaccharide (los) provenant de souches modifiees de neisseria meningitidis d'immunotype l6
NZ597004A (en) 2009-05-14 2013-03-28 Sanofi Pasteur Method for admixing the lipopolysaccharide (lps) of gram-negative bacteria
TWI548746B (zh) * 2009-08-06 2016-09-11 英特威特國際股份有限公司 防備豬胸膜肺炎之疫苗及製備該疫苗之方法
CN111511910A (zh) * 2017-12-22 2020-08-07 韩美药品株式会社 具有新颖结构的治疗酶融合蛋白及其用途
US20230287048A1 (en) * 2020-03-20 2023-09-14 HLB Science Inc. Composition and kit for removing lipopolysaccharide

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5371186A (en) * 1991-02-11 1994-12-06 Biosynth S.R.L. Synthetic peptides for detoxification of bacterial endotoxins and for the prevention and treatment of septic shock
WO2004052394A1 (en) * 2002-12-06 2004-06-24 Biosynth S.R.L. Broad-spectrum lps based vaccines of unencapsulated strains of haemophilus influenzae and other pathogenic species of gram-negative bacteria

Also Published As

Publication number Publication date
KR20070118646A (ko) 2007-12-17
AU2006233634A1 (en) 2006-10-19
EP1871787A2 (en) 2008-01-02
JP2008537749A (ja) 2008-09-25
CA2603850A1 (en) 2006-10-19
BRPI0610701A2 (pt) 2010-07-20
WO2006108586A3 (en) 2006-12-14
MX2007012457A (es) 2007-12-10
WO2006108586A2 (en) 2006-10-19
IL186322A0 (en) 2008-01-20
NO20075753L (no) 2007-11-09

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Legal Events

Date Code Title Description
PSEA Patent sealed
RENW Renewal (renewal fees accepted)
LAPS Patent lapsed