NZ538958A - Treating disorders of the retina by increasing the in vivo concentration of endostatin in ocular tissues - Google Patents
Treating disorders of the retina by increasing the in vivo concentration of endostatin in ocular tissuesInfo
- Publication number
- NZ538958A NZ538958A NZ538958A NZ53895803A NZ538958A NZ 538958 A NZ538958 A NZ 538958A NZ 538958 A NZ538958 A NZ 538958A NZ 53895803 A NZ53895803 A NZ 53895803A NZ 538958 A NZ538958 A NZ 538958A
- Authority
- NZ
- New Zealand
- Prior art keywords
- leu
- ser
- ala
- endostatin
- gly
- Prior art date
Links
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- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/39—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
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- A61K48/005—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'active' part of the composition delivered, i.e. the nucleic acid delivered
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Landscapes
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Applications Claiming Priority (2)
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| US40647002P | 2002-08-28 | 2002-08-28 | |
| PCT/EP2003/009497 WO2004020469A2 (en) | 2002-08-28 | 2003-08-27 | Ocular gene therapy |
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| NZ538958A true NZ538958A (en) | 2006-09-29 |
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| NZ538958A NZ538958A (en) | 2002-08-28 | 2003-08-27 | Treating disorders of the retina by increasing the in vivo concentration of endostatin in ocular tissues |
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| WO (1) | WO2004020469A2 (enExample) |
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| CN100475270C (zh) * | 2006-01-20 | 2009-04-08 | 清华大学 | 一种治疗肿瘤的药物及其应用 |
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| US6174861B1 (en) | 1996-10-22 | 2001-01-16 | The Children's Medical Center Corporation | Methods of inhibiting angiogenesis via increasing in vivo concentrations of endostatin protein |
| JP2001517433A (ja) * | 1997-09-24 | 2001-10-09 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | 非霊長類レンチウイルスベクターおよびパッケージングシステム |
| US6106826A (en) * | 1997-12-17 | 2000-08-22 | Wisconsin Alumni Research Foundation | Replication competent, avirulent Herpes simplex virus as a vector for neural and ocular gene therapy |
| US6670321B1 (en) * | 1998-12-30 | 2003-12-30 | The Children's Medical Center Corporation | Prevention and treatment for retinal ischemia and edema |
| US6267954B1 (en) * | 1999-11-24 | 2001-07-31 | Universite De Paris V Rene-Descartes | Intraocular transplantation of encapsulated cells |
| EP1280929A2 (en) * | 2000-05-01 | 2003-02-05 | Novartis AG | Vectors for ocular transduction and use thereof for genetic therapy |
| WO2001093897A2 (en) * | 2000-06-02 | 2001-12-13 | Entremed, Inc. | Angiostatin and endostatin binding proteins and methods of use |
| AU2002224403A1 (en) * | 2000-10-13 | 2002-04-22 | Entremed, Inc | Endostatin and pitslre protein kinases as angiogenesis-inhibiting peptides and method of use |
| EP1401480B1 (en) * | 2001-02-22 | 2012-11-28 | Novartis AG | Viral vectors encoding endostatin in the treatment of ocular neovascularization |
| AU2003225544A1 (en) * | 2002-02-04 | 2003-09-02 | Novartis Ag | Recombinant bovine immunodeficiency virus based gene transfer system |
| CA2480809A1 (en) * | 2002-04-11 | 2003-10-23 | Children's Medical Center Corporation | Methods for inhibiting vascular hyperpermeability |
| WO2004028635A1 (en) * | 2002-09-27 | 2004-04-08 | Novartis Ag | Ocular gene therapy |
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- 2003-08-27 CN CN200910150526A patent/CN101637611A/zh active Pending
- 2003-08-27 JP JP2004532124A patent/JP4612417B2/ja not_active Expired - Fee Related
- 2003-08-27 US US10/526,127 patent/US20070104684A1/en not_active Abandoned
- 2003-08-27 AT AT03790928T patent/ATE464321T1/de not_active IP Right Cessation
- 2003-08-27 WO PCT/EP2003/009497 patent/WO2004020469A2/en not_active Ceased
- 2003-08-27 DE DE60332122T patent/DE60332122D1/de not_active Expired - Lifetime
- 2003-08-27 CN CNB038231344A patent/CN100526332C/zh not_active Expired - Fee Related
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Also Published As
| Publication number | Publication date |
|---|---|
| WO2004020469A2 (en) | 2004-03-11 |
| CN101637611A (zh) | 2010-02-03 |
| JP2006516112A (ja) | 2006-06-22 |
| CN1708513A (zh) | 2005-12-14 |
| WO2004020469A3 (en) | 2004-04-29 |
| IL166950A (en) | 2011-04-28 |
| DE60332122D1 (de) | 2010-05-27 |
| EP1534751B1 (en) | 2010-04-14 |
| CA2496820A1 (en) | 2004-03-11 |
| AU2003258675B2 (en) | 2009-03-26 |
| AU2003258675A1 (en) | 2004-03-19 |
| HK1077306A1 (en) | 2006-02-10 |
| EP1534751A2 (en) | 2005-06-01 |
| US20070104684A1 (en) | 2007-05-10 |
| ATE464321T1 (de) | 2010-04-15 |
| JP4612417B2 (ja) | 2011-01-12 |
| CN100526332C (zh) | 2009-08-12 |
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