AU2002224403A1 - Endostatin and pitslre protein kinases as angiogenesis-inhibiting peptides and method of use - Google Patents

Endostatin and pitslre protein kinases as angiogenesis-inhibiting peptides and method of use

Info

Publication number
AU2002224403A1
AU2002224403A1 AU2002224403A AU2440302A AU2002224403A1 AU 2002224403 A1 AU2002224403 A1 AU 2002224403A1 AU 2002224403 A AU2002224403 A AU 2002224403A AU 2440302 A AU2440302 A AU 2440302A AU 2002224403 A1 AU2002224403 A1 AU 2002224403A1
Authority
AU
Australia
Prior art keywords
endostatin
angiogenesis
protein kinases
inhibiting peptides
pitslre protein
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2002224403A
Inventor
Hong Liang
Kim Lee Sim
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Casi Pharmaceuticals Inc
Original Assignee
Entremed Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Entremed Inc filed Critical Entremed Inc
Publication of AU2002224403A1 publication Critical patent/AU2002224403A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1205—Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/45—Transferases (2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
AU2002224403A 2000-10-13 2001-10-15 Endostatin and pitslre protein kinases as angiogenesis-inhibiting peptides and method of use Abandoned AU2002224403A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US24012700P 2000-10-13 2000-10-13
US60/240,127 2000-10-13
PCT/US2001/032437 WO2002030982A2 (en) 2000-10-13 2001-10-15 Endostatin and pitslre protein kinases as angiogenesis-inhibiting peptides and method of use

Publications (1)

Publication Number Publication Date
AU2002224403A1 true AU2002224403A1 (en) 2002-04-22

Family

ID=22905218

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2002224403A Abandoned AU2002224403A1 (en) 2000-10-13 2001-10-15 Endostatin and pitslre protein kinases as angiogenesis-inhibiting peptides and method of use

Country Status (3)

Country Link
US (1) US20020086007A1 (en)
AU (1) AU2002224403A1 (en)
WO (1) WO2002030982A2 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2815541B1 (en) * 2000-10-24 2008-02-29 Lipha USE OF PERICYTE APOPTOSIS INHIBITORS FOR THE TREATMENT AND / OR PREVENTION OF DIABETIC RETINOPATHY
WO2002067971A2 (en) 2001-02-22 2002-09-06 Novartis Ag Use of endostatin in the treatment of ocular neovascularization
US20070104684A1 (en) * 2002-08-28 2007-05-10 Campochiaro Peter A Ocular gene therapy
US7524811B2 (en) 2003-08-29 2009-04-28 Children's Medical Center Corporation Anti-angiogenic peptides from the N-terminus of endostatin
AU2004269399A1 (en) * 2003-08-29 2005-03-10 Children's Medical Center Corporation Anti-angiogenic peptides from the N-terminus of endostatin
EP2649095B1 (en) 2010-12-10 2021-10-06 Aleksander S. Popel Mimetic peptides derived from collagen type iv and their use for treating angiogenesis- and lymphangiogenesis- dependent diseases

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1202932A (en) * 1995-10-23 1998-12-23 儿童医学中心公司 Therapeutic antiangiogenic compositions and methods
EP1147188B1 (en) * 1999-01-26 2007-05-16 Vlaams Interuniversitair Instituut voor Biotechnologie vzw. Internal ribosome entry site (ires), vector containing same and the uses thereof
AU2001238347A1 (en) * 2000-02-28 2001-09-12 Hyseq, Inc. Novel nucleic acids and polypeptides

Also Published As

Publication number Publication date
WO2002030982A2 (en) 2002-04-18
US20020086007A1 (en) 2002-07-04
WO2002030982A3 (en) 2003-03-06

Similar Documents

Publication Publication Date Title
WO2002083921A8 (en) Nuleic acids and corresponding proteins useful in the detection and treatment of various cancers
AU2002230831A1 (en) Compositions of human proteins and method of use thereof
AU1926001A (en) Novel human protein kinases and protein kinase-like enzymes
AU5455900A (en) Heart homing peptides and methods of using same
AU2001267475A1 (en) Combinations of Enzyme Inhibitor-Containing Preparations and the use thereof
AU8079901A (en) Promyostatin peptides and methods of using same
WO2003059257A8 (en) Anti-angiogenic proteins and fragmentsand methods of use thereof
AU2002255952A1 (en) Short bioactive peptides and methods for their use
AU2002365404A1 (en) Solid-phase immobilization of proteins and peptides
AU2002246808A1 (en) Human nucleic acids and polypeptides and methods of use thereof
AU7748200A (en) Hypoxia-related human genes, proteins, and uses thereof
AU2002343601A1 (en) Proteins involved in regulation of adipocytes and uses related thereto
AU2002224403A1 (en) Endostatin and pitslre protein kinases as angiogenesis-inhibiting peptides and method of use
AU2002365202A1 (en) Synthetic genes for malarial proteins and methods of use
AU2001272932A1 (en) Angiostatin and endostatin binding proteins and methods of use
AU2001234544A1 (en) Novel human protein kinases and protein kinase-like enzymes
AU8542701A (en) Stress proteins and peptides and methods of use thereof
AU2002341828A1 (en) Enhanced proteins and methods for their use
AU7846000A (en) Novel human lipase proteins, nucleic acids encoding them, and uses of both of these
AU2001264934A1 (en) Dna repair polypeptides and methods of use
AU2001266813A1 (en) Human proteins and nucleic acids encoding same
AU5634400A (en) Shank proteins and methods of use thereof
AUPQ599500A0 (en) Novel peptides, modulatory agents therefor and methods of using them
AUPR595601A0 (en) Hypoglycaemic peptides and methods of use thereof
AU5495500A (en) Decorin binding protein essential peptides and methods of use