NZ516743A - Methods for treating or preventing pain and anxiety - Google Patents
Methods for treating or preventing pain and anxietyInfo
- Publication number
- NZ516743A NZ516743A NZ516743A NZ51674300A NZ516743A NZ 516743 A NZ516743 A NZ 516743A NZ 516743 A NZ516743 A NZ 516743A NZ 51674300 A NZ51674300 A NZ 51674300A NZ 516743 A NZ516743 A NZ 516743A
- Authority
- NZ
- New Zealand
- Prior art keywords
- substituted
- alkyl
- aryl
- kcnq
- heteroaryl
- Prior art date
Links
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Classifications
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- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/75—Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
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- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Health & Medical Sciences (AREA)
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- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US14722199P | 1999-08-04 | 1999-08-04 | |
| US15871299P | 1999-10-08 | 1999-10-08 | |
| US16584799P | 1999-11-16 | 1999-11-16 | |
| PCT/US2000/021309 WO2001010381A2 (en) | 1999-08-04 | 2000-08-04 | Methods for treating or preventing pain and anxiety |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NZ516743A true NZ516743A (en) | 2004-02-27 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NZ516743A NZ516743A (en) | 1999-08-04 | 2000-08-04 | Methods for treating or preventing pain and anxiety |
| NZ527771A NZ527771A (en) | 1999-08-04 | 2000-08-04 | Methods for treating or preventing anxiety |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NZ527771A NZ527771A (en) | 1999-08-04 | 2000-08-04 | Methods for treating or preventing anxiety |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US6326385B1 (https=) |
| EP (1) | EP1200086A4 (https=) |
| JP (1) | JP2003506388A (https=) |
| AU (1) | AU772075B2 (https=) |
| BR (1) | BR0012934A (https=) |
| CA (1) | CA2378243C (https=) |
| NZ (2) | NZ516743A (https=) |
| WO (1) | WO2001010381A2 (https=) |
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| DK1169060T3 (da) * | 1999-04-09 | 2006-01-16 | Euro Celtique Sa | Natriumkanalblokkerpræparater og anvendelse deraf |
| EP1200086A4 (en) * | 1999-08-04 | 2009-05-27 | Icagen Inc | THERAPEUTIC OR PROPHYLACTIC METHODS OF PAIN AND ANXIETY |
| MXPA03000032A (es) * | 2000-06-29 | 2003-08-19 | Neurosearch As | Uso de derivados de oxindol 3-sustituidos como moduladores de los canales de potasio kcnq. |
| US6589986B2 (en) | 2000-12-20 | 2003-07-08 | Wyeth | Methods of treating anxiety disorders |
| CZ20032233A3 (cs) * | 2001-02-20 | 2004-12-15 | Bristol-Myers Squibb Company | Derivát 2,4-disubstituovaného pyrimidin-5-karboxamidu jako modulátor draslíkového kanálku KCNQ |
| CA2438868A1 (en) | 2001-02-20 | 2002-09-19 | Valentin K. Gribkoff | Modulators of kcnq potassium channels and use thereof in treating migraine and mechanistically related diseases |
| HUP0401750A2 (hu) | 2001-05-31 | 2004-12-28 | Bristol-Myers Squibb Company | Cinnamidszármazékok mint KCNQ káliumcsatorna-modulátorok és ezeket tartalmazó gyógyszerkészítmények |
| DK1423168T3 (da) * | 2001-09-03 | 2006-05-15 | Newron Pharm Spa | Farmaceutisk præparat omfattende gabapentin eller en analog deraf og et alfa-aminoamid og dets analgetiske anvendelse |
| US7205307B2 (en) * | 2002-02-14 | 2007-04-17 | Icagen, Inc. | Pyrimidines as novel openers of potassium ion channels |
| AU2003259846A1 (en) * | 2002-08-16 | 2004-03-03 | The General Hospital Corporation | Non-invasive functional imaging of peripheral nervous system activation in humans and animals |
| US7632866B2 (en) | 2002-10-21 | 2009-12-15 | Ramot At Tel Aviv University | Derivatives of N-phenylanthranilic acid and 2-benzimidazolone as potassium channel and/or neuron activity modulators |
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-
2000
- 2000-08-04 EP EP00955368A patent/EP1200086A4/en not_active Withdrawn
- 2000-08-04 AU AU67586/00A patent/AU772075B2/en not_active Ceased
- 2000-08-04 NZ NZ516743A patent/NZ516743A/en not_active IP Right Cessation
- 2000-08-04 WO PCT/US2000/021309 patent/WO2001010381A2/en not_active Ceased
- 2000-08-04 US US09/631,747 patent/US6326385B1/en not_active Expired - Lifetime
- 2000-08-04 BR BR0012934-8A patent/BR0012934A/pt not_active Application Discontinuation
- 2000-08-04 JP JP2001514906A patent/JP2003506388A/ja active Pending
- 2000-08-04 CA CA2378243A patent/CA2378243C/en not_active Expired - Fee Related
- 2000-08-04 NZ NZ527771A patent/NZ527771A/en not_active IP Right Cessation
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| CA2378243C (en) | 2012-05-15 |
| US20020013349A1 (en) | 2002-01-31 |
| JP2003506388A (ja) | 2003-02-18 |
| US6326385B1 (en) | 2001-12-04 |
| AU6758600A (en) | 2001-03-05 |
| BR0012934A (pt) | 2003-07-29 |
| WO2001010381A2 (en) | 2001-02-15 |
| NZ527771A (en) | 2005-04-29 |
| EP1200086A4 (en) | 2009-05-27 |
| EP1200086A2 (en) | 2002-05-02 |
| CA2378243A1 (en) | 2001-02-15 |
| AU772075B2 (en) | 2004-04-08 |
| WO2001010381A3 (en) | 2001-08-16 |
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