NZ516743A - Methods for treating or preventing pain and anxiety - Google Patents
Methods for treating or preventing pain and anxietyInfo
- Publication number
- NZ516743A NZ516743A NZ516743A NZ51674300A NZ516743A NZ 516743 A NZ516743 A NZ 516743A NZ 516743 A NZ516743 A NZ 516743A NZ 51674300 A NZ51674300 A NZ 51674300A NZ 516743 A NZ516743 A NZ 516743A
- Authority
- NZ
- New Zealand
- Prior art keywords
- substituted
- alkyl
- aryl
- kcnq
- heteroaryl
- Prior art date
Links
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Classifications
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- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/75—Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
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- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
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- Life Sciences & Earth Sciences (AREA)
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- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pyridine Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US14722199P | 1999-08-04 | 1999-08-04 | |
| US15871299P | 1999-10-08 | 1999-10-08 | |
| US16584799P | 1999-11-16 | 1999-11-16 | |
| PCT/US2000/021309 WO2001010381A2 (en) | 1999-08-04 | 2000-08-04 | Methods for treating or preventing pain and anxiety |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NZ516743A true NZ516743A (en) | 2004-02-27 |
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| Application Number | Title | Priority Date | Filing Date |
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| NZ516743A NZ516743A (en) | 1999-08-04 | 2000-08-04 | Methods for treating or preventing pain and anxiety |
| NZ527771A NZ527771A (en) | 1999-08-04 | 2000-08-04 | Methods for treating or preventing anxiety |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NZ527771A NZ527771A (en) | 1999-08-04 | 2000-08-04 | Methods for treating or preventing anxiety |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US6326385B1 (enExample) |
| EP (1) | EP1200086A4 (enExample) |
| JP (1) | JP2003506388A (enExample) |
| AU (1) | AU772075B2 (enExample) |
| BR (1) | BR0012934A (enExample) |
| CA (1) | CA2378243C (enExample) |
| NZ (2) | NZ516743A (enExample) |
| WO (1) | WO2001010381A2 (enExample) |
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| DK1169060T3 (da) * | 1999-04-09 | 2006-01-16 | Euro Celtique Sa | Natriumkanalblokkerpræparater og anvendelse deraf |
| US6326385B1 (en) * | 1999-08-04 | 2001-12-04 | Icagen, Inc. | Methods for treating or preventing pain |
| WO2002000217A1 (en) * | 2000-06-29 | 2002-01-03 | Neurosearch A/S | Use of 3-substituted oxindole derivatives as kcnq potassium channel modulators |
| US6589986B2 (en) | 2000-12-20 | 2003-07-08 | Wyeth | Methods of treating anxiety disorders |
| US6855829B2 (en) | 2001-02-20 | 2005-02-15 | Bristol-Myers Squibb Company | 3-fluoro-2-oxindole modulators of KCNQ potassium channels and use thereof in treating migraine and mechanistically related disease |
| HUP0303841A2 (hu) * | 2001-02-20 | 2004-03-01 | Bristol-Myers Squibb Company | 2,4-Diszubsztituált-5-pirimidinkarboxamid-származékok mint KCNQ káliumcsatorna modulátorok és ezeket tartalmazó gyógyszerkészítmények és előállításuk |
| US6831080B2 (en) | 2001-05-31 | 2004-12-14 | Bristol-Myers Squibb Company | Cinnamide derivatives as KCNQ potassium channel modulators |
| ATE317280T1 (de) * | 2001-09-03 | 2006-02-15 | Newron Pharm Spa | Pharmazeutische zusammensetzung mit gabapentin oder deren analog und einem alpha-aminoamid und analgetische verwendung dieser zusammensetzung |
| US7205307B2 (en) * | 2002-02-14 | 2007-04-17 | Icagen, Inc. | Pyrimidines as novel openers of potassium ion channels |
| WO2004016167A1 (en) * | 2002-08-16 | 2004-02-26 | The General Hospital Corporation | Non-invasive functional imaging of peripheral nervous system activation in humans and animals |
| US7632866B2 (en) * | 2002-10-21 | 2009-12-15 | Ramot At Tel Aviv University | Derivatives of N-phenylanthranilic acid and 2-benzimidazolone as potassium channel and/or neuron activity modulators |
| EP1581516A4 (en) | 2002-11-22 | 2007-10-17 | Bristol Myers Squibb Co | BENZYLAMIDE 3-HETEROCYCLIC DERIVATIVES AS POTASIC CHANNEL OPENING AGENTS |
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2000
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- 2000-08-04 CA CA2378243A patent/CA2378243C/en not_active Expired - Fee Related
- 2000-08-04 AU AU67586/00A patent/AU772075B2/en not_active Ceased
- 2000-08-04 WO PCT/US2000/021309 patent/WO2001010381A2/en not_active Ceased
- 2000-08-04 EP EP00955368A patent/EP1200086A4/en not_active Withdrawn
- 2000-08-04 BR BR0012934-8A patent/BR0012934A/pt not_active Application Discontinuation
- 2000-08-04 NZ NZ516743A patent/NZ516743A/en not_active IP Right Cessation
- 2000-08-04 NZ NZ527771A patent/NZ527771A/en not_active IP Right Cessation
- 2000-08-04 JP JP2001514906A patent/JP2003506388A/ja active Pending
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| AU6758600A (en) | 2001-03-05 |
| CA2378243A1 (en) | 2001-02-15 |
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| US6326385B1 (en) | 2001-12-04 |
| EP1200086A2 (en) | 2002-05-02 |
| WO2001010381A2 (en) | 2001-02-15 |
| WO2001010381A3 (en) | 2001-08-16 |
| BR0012934A (pt) | 2003-07-29 |
| NZ527771A (en) | 2005-04-29 |
| EP1200086A4 (en) | 2009-05-27 |
| CA2378243C (en) | 2012-05-15 |
| AU772075B2 (en) | 2004-04-08 |
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