CA2378243C - Methods for treating or preventing pain and anxiety - Google Patents
Methods for treating or preventing pain and anxiety Download PDFInfo
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- CA2378243C CA2378243C CA2378243A CA2378243A CA2378243C CA 2378243 C CA2378243 C CA 2378243C CA 2378243 A CA2378243 A CA 2378243A CA 2378243 A CA2378243 A CA 2378243A CA 2378243 C CA2378243 C CA 2378243C
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Classifications
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- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
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- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
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- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
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- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
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- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
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Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
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| US15871299P | 1999-10-08 | 1999-10-08 | |
| US60/158,712 | 1999-10-08 | ||
| US16584799P | 1999-11-16 | 1999-11-16 | |
| US60/165,847 | 1999-11-16 | ||
| PCT/US2000/021309 WO2001010381A2 (en) | 1999-08-04 | 2000-08-04 | Methods for treating or preventing pain and anxiety |
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| CA2378243A1 CA2378243A1 (en) | 2001-02-15 |
| CA2378243C true CA2378243C (en) | 2012-05-15 |
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| CA2378243A Expired - Fee Related CA2378243C (en) | 1999-08-04 | 2000-08-04 | Methods for treating or preventing pain and anxiety |
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| Country | Link |
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| US (2) | US6326385B1 (enExample) |
| EP (1) | EP1200086A4 (enExample) |
| JP (1) | JP2003506388A (enExample) |
| AU (1) | AU772075B2 (enExample) |
| BR (1) | BR0012934A (enExample) |
| CA (1) | CA2378243C (enExample) |
| NZ (2) | NZ527771A (enExample) |
| WO (1) | WO2001010381A2 (enExample) |
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| US8722929B2 (en) * | 2006-10-10 | 2014-05-13 | Valeant Pharmaceuticals International | N-[2-amino-4-(phenylmethoxy)phenyl] amides and related compounds as potassium channel modulators |
| AU2007325629A1 (en) * | 2006-11-28 | 2008-06-05 | Valeant Pharmaceuticals International | 1,4 diamino bicyclic retigabine analogues as potassium channel modulators |
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| US8367684B2 (en) * | 2007-06-13 | 2013-02-05 | Valeant Pharmaceuticals International | Derivatives of 4-(N-azacycloalkyl) anilides as potassium channel modulators |
| US8563566B2 (en) | 2007-08-01 | 2013-10-22 | Valeant Pharmaceuticals International | Naphthyridine derivatives as potassium channel modulators |
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| CN101868443A (zh) | 2007-09-20 | 2010-10-20 | 特拉维夫大学拉莫特有限公司 | N-苯基邻氨基苯甲酸衍生物及其用途 |
| US20100323015A1 (en) * | 2008-07-18 | 2010-12-23 | Biljana Nadjsombati | Modified release formulation and methods of use |
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| TWI475020B (zh) * | 2009-03-12 | 2015-03-01 | The substituted nicotine amide as a KCNQ2 / 3 modifier | |
| MX342119B (es) | 2010-08-27 | 2016-09-14 | Grünenthal Gmbh * | 2-oxi-quinolin-3-carboxamidas sustituidas como moduladores de kcnq2/3. |
| US8653102B2 (en) | 2010-08-27 | 2014-02-18 | Gruenenthal Gmbh | Substituted 2-oxo- and 2-thioxo-dihydroquinoline-3-carboxamides as KCNQ2/3 modulators |
| CA2805932A1 (en) | 2010-08-27 | 2012-03-01 | Gruenenthal Gmbh | Substituted 2-amino-quinoline-3-carboxamides as kcnq2/3 modulators |
| EP2611780A1 (en) | 2010-09-01 | 2013-07-10 | Grünenthal GmbH | Substituted 1-oxo-dihydroisoquinoline-3-carboxamides as kcnq2/3 modulators |
| WO2013067591A1 (en) * | 2011-11-10 | 2013-05-16 | Relevare Australia Pty Ltd | Topical formulations for pain management |
| US9458464B2 (en) | 2014-06-23 | 2016-10-04 | The Johns Hopkins University | Treatment of neuropathic pain |
| WO2018204765A1 (en) * | 2017-05-05 | 2018-11-08 | Pairnomix, Llc | Methods of treating epilepsy and kcnq2 related conditions |
| TWI886158B (zh) | 2019-10-10 | 2025-06-11 | 加拿大商再諾製藥公司 | 選擇性鉀通道調節劑之固態晶型 |
| PH12022551110A1 (en) | 2019-11-08 | 2024-02-26 | Xenon Pharmaceuticals Inc | Methods of treating depressive disorders |
| JP2024508660A (ja) | 2021-02-09 | 2024-02-28 | ゼノン・ファーマシューティカルズ・インコーポレイテッド | 快感消失の治療に使用するための電位依存性カリウムチャネル開口薬 |
| KR102863193B1 (ko) * | 2023-03-13 | 2025-09-22 | 대구가톨릭대학교산학협력단 | 리도카인 유도체를 유효성분으로 포함하는 항염증용 조성물 |
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| GB9726339D0 (en) | 1997-12-13 | 1998-02-11 | Zeneca Ltd | Human-derived tissue-specific potassium channel |
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| ATE380176T1 (de) * | 1999-08-04 | 2007-12-15 | Icagen Inc | Benzanilide als öffner des kaliumkanals |
| US6326385B1 (en) * | 1999-08-04 | 2001-12-04 | Icagen, Inc. | Methods for treating or preventing pain |
| US6593349B2 (en) * | 2001-03-19 | 2003-07-15 | Icagen, Inc. | Bisarylamines as potassium channel openers |
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2000
- 2000-08-04 US US09/631,747 patent/US6326385B1/en not_active Expired - Lifetime
- 2000-08-04 WO PCT/US2000/021309 patent/WO2001010381A2/en not_active Ceased
- 2000-08-04 JP JP2001514906A patent/JP2003506388A/ja active Pending
- 2000-08-04 BR BR0012934-8A patent/BR0012934A/pt not_active Application Discontinuation
- 2000-08-04 EP EP00955368A patent/EP1200086A4/en not_active Withdrawn
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Also Published As
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|---|---|
| US20020013349A1 (en) | 2002-01-31 |
| EP1200086A4 (en) | 2009-05-27 |
| EP1200086A2 (en) | 2002-05-02 |
| AU772075B2 (en) | 2004-04-08 |
| US6326385B1 (en) | 2001-12-04 |
| WO2001010381A3 (en) | 2001-08-16 |
| WO2001010381A2 (en) | 2001-02-15 |
| JP2003506388A (ja) | 2003-02-18 |
| NZ516743A (en) | 2004-02-27 |
| AU6758600A (en) | 2001-03-05 |
| CA2378243A1 (en) | 2001-02-15 |
| BR0012934A (pt) | 2003-07-29 |
| NZ527771A (en) | 2005-04-29 |
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| EEER | Examination request | ||
| MKLA | Lapsed |
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