NZ516173A - Methods for manipulating the avian genome - Google Patents
Methods for manipulating the avian genomeInfo
- Publication number
- NZ516173A NZ516173A NZ516173A NZ51617300A NZ516173A NZ 516173 A NZ516173 A NZ 516173A NZ 516173 A NZ516173 A NZ 516173A NZ 51617300 A NZ51617300 A NZ 51617300A NZ 516173 A NZ516173 A NZ 516173A
- Authority
- NZ
- New Zealand
- Prior art keywords
- nucleic acid
- acid molecule
- genome
- manipulating
- methods
- Prior art date
Links
- 241000271566 Aves Species 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 2
- 102000039446 nucleic acids Human genes 0.000 abstract 6
- 108020004707 nucleic acids Proteins 0.000 abstract 6
- 150000007523 nucleic acids Chemical class 0.000 abstract 6
- 210000004027 cell Anatomy 0.000 abstract 2
- 108090000565 Capsid Proteins Proteins 0.000 abstract 1
- 210000002298 blastodisc Anatomy 0.000 abstract 1
- 210000000349 chromosome Anatomy 0.000 abstract 1
- 238000001727 in vivo Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/8509—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells for producing genetically modified animals, e.g. transgenic
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
- A01K67/027—New or modified breeds of vertebrates
- A01K67/0275—Genetically modified vertebrates, e.g. transgenic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/62—Insulins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/02—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies from eggs
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2227/00—Animals characterised by species
- A01K2227/30—Bird
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2267/00—Animals characterised by purpose
- A01K2267/01—Animal expressing industrially exogenous proteins
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2267/00—Animals characterised by purpose
- A01K2267/02—Animal zootechnically ameliorated
- A01K2267/025—Animal producing cells or organs for transplantation
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/008—Vector systems having a special element relevant for transcription cell type or tissue specific enhancer/promoter combination
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/46—Vector systems having a special element relevant for transcription elements influencing chromatin structure, e.g. scaffold/matrix attachment region, methylation free island
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/80—Vector systems having a special element relevant for transcription from vertebrates
- C12N2830/85—Vector systems having a special element relevant for transcription from vertebrates mammalian
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/80—Vector systems having a special element relevant for transcription from vertebrates
- C12N2830/90—Vector systems having a special element relevant for transcription from vertebrates avian
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- Environmental Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Husbandry (AREA)
- Gastroenterology & Hepatology (AREA)
- Biodiversity & Conservation Biology (AREA)
- Physics & Mathematics (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Toxicology (AREA)
- Animal Behavior & Ethology (AREA)
- Microbiology (AREA)
- Plant Pathology (AREA)
- Immunology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
A method for introducing a nucleic acid molecule into the genome of an avian species, comprising contacting in vivo a blastodermal cell in a laid fertilized egg with an isolated nucleic acid molecule, wherein (a) said nucleic acid molecule is not associated with a viral coat protein, (b) wherein said nucleic acid molecule is introduced directly into the germinal disc of said egg in a volume of greater than 1 microlitre and less than 0.5 millilitres, and (c) said nucleic acid molecule is integrated into a host chromosome of said blastodermal cell, thereby introducing said nucleic acid molecule into the genome of said avian species.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US13776199P | 1999-06-04 | 1999-06-04 | |
PCT/US2000/040059 WO2000075300A2 (en) | 1999-06-04 | 2000-06-02 | Methods for manipulating the avian genome |
Publications (1)
Publication Number | Publication Date |
---|---|
NZ516173A true NZ516173A (en) | 2004-02-27 |
Family
ID=22478939
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NZ516173A NZ516173A (en) | 1999-06-04 | 2000-06-02 | Methods for manipulating the avian genome |
Country Status (6)
Country | Link |
---|---|
EP (1) | EP1190042A2 (en) |
JP (1) | JP2003501083A (en) |
AU (1) | AU777420B2 (en) |
CA (1) | CA2375441A1 (en) |
NZ (1) | NZ516173A (en) |
WO (1) | WO2000075300A2 (en) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2044839A3 (en) | 2000-08-03 | 2009-07-01 | Therapeutic Human Polyclonals, Inc. | Production of humanized antibodies in transgenic animals |
US20020108132A1 (en) * | 2001-02-02 | 2002-08-08 | Avigenics Inc. | Production of a monoclonal antibody by a transgenic chicken |
CN1568366B (en) | 2001-08-13 | 2013-04-24 | 恩布里克斯公司 | Methods for injecting avian eggs |
ATE513038T1 (en) * | 2001-09-18 | 2011-07-15 | Synageva Biopharma Corp | PRODUCTION OF A TRANSGENIC BIRD USING CYTOPLASM INJECTION |
WO2003024199A2 (en) * | 2001-09-21 | 2003-03-27 | Avigenics, Inc. | Production of transgenic avians using sperm-mediated transfection |
US7145057B2 (en) | 2002-02-01 | 2006-12-05 | Origen Therapeutics, Inc. | Chimeric bird from embryonic stem cells |
US20060191026A1 (en) | 2005-02-18 | 2006-08-24 | Origen Therapeutics, Inc. | Tissue specific expression of antibodies in chickens |
US7323618B2 (en) | 2002-02-01 | 2008-01-29 | Origen Therapeutics, Inc. | Tissue specific expression of exogenous proteins in transgenic chickens |
US20030176660A1 (en) * | 2002-02-08 | 2003-09-18 | Ransohoff Thomas C. | Immunoglobulin purification |
WO2004094640A1 (en) * | 2003-04-15 | 2004-11-04 | University Of Georgia Research Foundation, Inc. | Avian transgenesis using a chicken ovalbumin gene region |
MXPA06000562A (en) | 2003-07-15 | 2006-03-30 | Therapeutic Human Polyclonals | Humanized immunoglobulin loci. |
EP2064325B1 (en) | 2006-09-01 | 2011-12-07 | Therapeutic Human Polyclonals, Inc. | Enhanced expression of human or humanized immunoglobulin in non-human transgenic animals |
JP6156144B2 (en) | 2011-09-21 | 2017-07-05 | 富士レビオ株式会社 | Antibodies against affinity complexes |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5162215A (en) * | 1988-09-22 | 1992-11-10 | Amgen Inc. | Method of gene transfer into chickens and other avian species |
EP0424044A1 (en) * | 1989-10-16 | 1991-04-24 | Merck & Co. Inc. | Transgenic fowl expressing bovine growth hormone |
GB2282139A (en) * | 1993-09-24 | 1995-03-29 | Univ Reading | Introducing DNA into the germ line of birds |
CA2259908A1 (en) * | 1996-07-08 | 1998-01-15 | Dnavec Research Inc. | In vivo electroporation method for early animal embryo |
EP1007697B1 (en) * | 1997-08-22 | 2007-03-14 | University Of Guelph | Production of proteins in eggs |
PT1023442E (en) * | 1997-10-16 | 2011-02-25 | Synageva Biopharma Corp | Transgenic birds and protein production |
-
2000
- 2000-06-02 AU AU57898/00A patent/AU777420B2/en not_active Ceased
- 2000-06-02 EP EP00943424A patent/EP1190042A2/en not_active Withdrawn
- 2000-06-02 WO PCT/US2000/040059 patent/WO2000075300A2/en not_active Application Discontinuation
- 2000-06-02 JP JP2001502566A patent/JP2003501083A/en not_active Withdrawn
- 2000-06-02 CA CA002375441A patent/CA2375441A1/en not_active Abandoned
- 2000-06-02 NZ NZ516173A patent/NZ516173A/en unknown
Also Published As
Publication number | Publication date |
---|---|
AU5789800A (en) | 2000-12-28 |
EP1190042A2 (en) | 2002-03-27 |
JP2003501083A (en) | 2003-01-14 |
CA2375441A1 (en) | 2000-12-14 |
WO2000075300A2 (en) | 2000-12-14 |
WO2000075300A3 (en) | 2002-01-10 |
AU777420B2 (en) | 2004-10-14 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
NZ516173A (en) | Methods for manipulating the avian genome | |
DE59611371D1 (en) | Process for the preparation of erythropoietin free of animal proteins | |
WO1998039485A3 (en) | Compositions and methods for analysis of nucleic acids | |
WO1998011243A3 (en) | Expression of an exogenous gene in a mammalian cell by use of a non-mammalian dna virus having an altered coat protein | |
MY157028A (en) | Mammalian cytokine, related reagents | |
DE69941044D1 (en) | Methods, apparatus and computer program for the quantitative determination of nucleic acid sequences in samples using standard curves and estimates of amplification ratios | |
LTIP1826A (en) | Process for preparing transformed prokaryotic host cell, stable gene amplification in the chromosome dna of prokaryotic microorganisms | |
WO2000077233A3 (en) | Complement-resistant non-mammalian dna viruses and uses thereof | |
HK1086297A1 (en) | Circular dna molecule having a conditional origin of replication and process for preparation | |
AP9901654A0 (en) | Gene sequencer and methods. | |
UA48936C2 (en) | Method for production of chicken anemia virus (cav) in two chain form, recombinant nucleate acid (variants), diagnostic set (variants), vaccination preparation (variants), cell culture (variants), method for production of diagnostic set (variants) | |
AU8110487A (en) | DNA molecules coding for proteins targeted to plant cell walls | |
TR199802648A3 (en) | Nucleic acid constructs for gene therapy. | |
ATE471980T1 (en) | ISOLATION OF DNA MOLECULES USING ARYLMERCAPTO LIGANDS | |
AU4985201A (en) | Human gene critical to fertility | |
NO921798L (en) | PROCEDURE AND REAGENTS FOR GAMMA GLOBIN TYPE DETERMINATION | |
CA2037677A1 (en) | Process for production of exogenous gene or its product in plant cells | |
WO2001046463A3 (en) | Methods for the preparation and use of internal standards for nucleic acid amplification assays | |
WO1999011799A3 (en) | Human aminopeptidase p gene | |
WO1996009399A3 (en) | Chimeric adenovirus for gene delivery | |
EP0859059A3 (en) | Methods and materials for introducing exogenous genes into cultured cells or fertilized eggs | |
ES2189560A1 (en) | Dna polymerase lambda and uses thereof | |
WO1999047673A3 (en) | Isolated mammalian membrane protein genes and related reagents | |
MXPA02004825A (en) | Genes specifically expressed in human dendritic cells. | |
EP2055779A3 (en) | Auxin transport proteins |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PSEA | Patent sealed | ||
RENW | Renewal (renewal fees accepted) |