NZ232868A - An intranasal composition comprising an icam - Google Patents

An intranasal composition comprising an icam

Info

Publication number
NZ232868A
NZ232868A NZ232868A NZ23286890A NZ232868A NZ 232868 A NZ232868 A NZ 232868A NZ 232868 A NZ232868 A NZ 232868A NZ 23286890 A NZ23286890 A NZ 23286890A NZ 232868 A NZ232868 A NZ 232868A
Authority
NZ
New Zealand
Prior art keywords
icam
family
glycoproteins
asthma
antibody
Prior art date
Application number
NZ232868A
Other languages
English (en)
Inventor
Craig D Wegner
Robert H Gundel
Robert Rothlein
Angel A Corbi
Timothy A Springer
K Kishimoto Takashi
Thomas Roberts
Steven D Marlin
Michael L Dustin
Original Assignee
Boehringer Ingelheim Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Pharma filed Critical Boehringer Ingelheim Pharma
Publication of NZ232868A publication Critical patent/NZ232868A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/70525—ICAM molecules, e.g. CD50, CD54, CD102
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70546—Integrin superfamily
    • C07K14/70553—Integrin beta2-subunit-containing molecules, e.g. CD11, CD18
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2821—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against ICAM molecules, e.g. CD50, CD54, CD102
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2839—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily
    • C07K16/2845—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily against integrin beta2-subunit-containing molecules, e.g. CD11, CD18
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pulmonology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Cell Biology (AREA)
  • Epidemiology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
NZ232868A 1989-03-09 1990-03-09 An intranasal composition comprising an icam NZ232868A (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US32101889A 1989-03-09 1989-03-09
US32123989A 1989-03-09 1989-03-09
US32123789A 1989-03-09 1989-03-09
US32448189A 1989-03-16 1989-03-16
US40140989A 1989-09-01 1989-09-01

Publications (1)

Publication Number Publication Date
NZ232868A true NZ232868A (en) 1995-05-26

Family

ID=27541038

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ232868A NZ232868A (en) 1989-03-09 1990-03-09 An intranasal composition comprising an icam

Country Status (13)

Country Link
EP (1) EP0387701B1 (forum.php)
JP (1) JP3119483B2 (forum.php)
KR (1) KR0177519B1 (forum.php)
AT (1) ATE79270T1 (forum.php)
AU (1) AU638450B2 (forum.php)
CA (1) CA2047721C (forum.php)
DE (1) DE69000248T2 (forum.php)
DK (1) DK0387701T3 (forum.php)
ES (1) ES2035668T3 (forum.php)
GR (1) GR3006073T3 (forum.php)
HU (1) HU216313B (forum.php)
NZ (1) NZ232868A (forum.php)
WO (1) WO1990010453A1 (forum.php)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE186552T1 (de) 1988-09-01 1999-11-15 Bayer Ag Menschliches rhinovirusrezeptorprotein, das die virusinfektionsanfälligkeit hemmt
US6514936B1 (en) 1988-09-01 2003-02-04 Bayer Corporation Antiviral methods using human rhinovirus receptor (ICAM-1)
US6051231A (en) * 1988-09-01 2000-04-18 Bayer Corporation Antiviral methods and prepations
ZA896668B (en) * 1988-09-01 1990-06-27 Molecular Therapeutics Inc A human rhinovirus receptor protein that inhibits virus infectivity
US6143298A (en) * 1988-09-01 2000-11-07 Bayer Corporation Soluble truncated forms of ICAM-1
US5776775A (en) * 1989-02-21 1998-07-07 Dana-Farber Cancer Institute Anti-LAM 1-3 antibody and hybridoma
US6107461A (en) * 1990-07-20 2000-08-22 Bayer Corporation Multimeric forms of human rhinovirus receptor and fragments thereof, and method of use
US5871733A (en) * 1990-07-20 1999-02-16 Bayer Corporation Multimeric forms of human rhinovirus receptor protein
ES2134762T3 (es) * 1990-07-20 1999-10-16 Bayer Ag Formas multimericas de proteinas receptoras de rinovirus humanos.
US5674982A (en) * 1990-07-20 1997-10-07 Bayer Corporation Multimeric form of human rhinovirus receptor protein
CA2092801A1 (en) * 1990-10-03 1992-04-04 Randall Barton Method for treating inflammation using anti-idiotypic antibodies
CA2056143A1 (en) * 1990-11-28 1992-05-29 Michael S. Diamond The mac-1 binding site of icam-1
ATE145827T1 (de) * 1991-04-03 1996-12-15 Boehringer Ingelheim Pharma Verfahren zur hemmung der sauerstofftoxizität in den lungen
GB9115364D0 (en) 1991-07-16 1991-08-28 Wellcome Found Antibody
HU215549B (hu) * 1991-07-31 1999-01-28 Baylor College Of Medicine Eljárás asztma kezelésére szolgáló gyógyszerkészítmények előállítására
HUT69725A (en) * 1991-10-01 1995-09-28 Gen Hospital Corp Process for producing compositions for preventing allograft rejection
US5871734A (en) * 1992-01-13 1999-02-16 Biogen, Inc. Treatment for asthma with VLA-4 blocking agents
US5708141A (en) * 1992-05-11 1998-01-13 Corvas International, Inc. Neutrophil inhibitors
FI946006A7 (fi) * 1992-06-22 1994-12-21 Bayer Corp Humaani-rinoviruksen reseptoriproteiinin multimeerisiä muotoja
US6391452B1 (en) 1997-07-18 2002-05-21 Bayer Corporation Compositions for nasal drug delivery, methods of making same, and methods of removing residual solvent from pharmaceutical preparations
US20030035798A1 (en) 2000-08-16 2003-02-20 Fang Fang Humanized antibodies
CA2454358A1 (en) 2001-07-19 2003-07-31 Perlan Therapeutics, Inc. Multimeric proteins and methods of making and using same
GB0525214D0 (en) 2005-12-12 2006-01-18 Bioinvent Int Ab Biological materials and uses thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3854536T2 (de) * 1987-05-04 1996-03-07 Dana Farber Cancer Inst Inc Interzellulare Adhäsions-Moleküle und deren Bindungsliganden.
ATE114972T1 (de) * 1987-11-02 1994-12-15 Baylor College Medicine Verwendung von icam-1 oder ihre funktionelle derivate zur behandlung unspezifischer entzündungen.
CA1341055C (en) * 1987-12-08 2000-07-18 Alan Mcclelland Transfectant cell lines which express the major human rhinovirus receptor

Also Published As

Publication number Publication date
CA2047721C (en) 2004-01-06
EP0387701B1 (en) 1992-08-12
KR920700667A (ko) 1992-08-10
HUT65843A (en) 1994-07-28
HU216313B (hu) 1999-06-28
DK0387701T3 (da) 1992-12-07
EP0387701A1 (en) 1990-09-19
ES2035668T3 (es) 1993-04-16
GR3006073T3 (forum.php) 1993-06-21
JP3119483B2 (ja) 2000-12-18
JPH04504127A (ja) 1992-07-23
DE69000248T2 (de) 1993-01-07
WO1990010453A1 (en) 1990-09-20
HU902883D0 (en) 1991-12-30
ATE79270T1 (de) 1992-08-15
AU5349990A (en) 1990-10-09
CA2047721A1 (en) 1990-09-10
AU638450B2 (en) 1993-07-01
KR0177519B1 (ko) 1999-03-20
DE69000248D1 (de) 1992-09-17

Similar Documents

Publication Publication Date Title
US5730983A (en) Use of intercellular adhesion molecules, and their binding ligands in the treatment of asthma
EP0387701B1 (en) Use of intercellular adhesion molecules, and their binding ligands in the treatment of asthma
JP3288042B2 (ja) 細胞間接着分子−３およびその結合リガンド
US7666432B2 (en) Methods of suppressing fibrosis and fibrocyte formation
EP0488061B1 (en) The MAC-1 binding site of ICAM-1
US5284931A (en) Intercellular adhesion molecules, and their binding ligands
US8187608B2 (en) Treatment of Fibrosis related disorders
CA2011633C (en) Intercellular adhesion molecule - 2 and its binding ligands
JPH08507860A (ja) リンパ球走化性誘引物質に基づくアッセイおよび治療方法
WO1993013798A1 (en) Treatment for asthma
JPH05503070A (ja) 新規の細胞外基質レセプター／リガンド相互作用を利用した血管内皮に対するリンパ球接着の抑止方法
WO1993006842A1 (en) Use of intercellular adhesion molecules, and their binding ligands in the treatment of asthma
US20090035321A1 (en) Intercellular adhesion molecules and their binding ligands
WO1995027736A1 (en) Use of agents which block intercellular adhesion molecule/receptor interaction in the treatment of respiratory viral infection
AU651633B2 (en) The Mac-1 binding site of ICAM-1
AU665232C (en) Treatment for asthma
MXPA96004715A (en) Use of agents that block the molecular interaction / receiver adhesion interaction in the treatment of viral infections respirator
DD297417A5 (de) Interzellulares adhaesionsmolekuel-2 und seine bindungsliganden

Legal Events

Date Code Title Description
RENW Renewal (renewal fees accepted)