NZ230763A - Production of granules having a core by spraying the cores with a dispersion of hydroxypropylcellulose, optionally incorporating an active ingredient - Google Patents
Production of granules having a core by spraying the cores with a dispersion of hydroxypropylcellulose, optionally incorporating an active ingredientInfo
- Publication number
- NZ230763A NZ230763A NZ230763A NZ23076389A NZ230763A NZ 230763 A NZ230763 A NZ 230763A NZ 230763 A NZ230763 A NZ 230763A NZ 23076389 A NZ23076389 A NZ 23076389A NZ 230763 A NZ230763 A NZ 230763A
- Authority
- NZ
- New Zealand
- Prior art keywords
- granules
- core
- dispersion
- spraying
- active ingredient
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
- A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/38—Cellulose; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/167—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface
- A61K9/1676—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface having a drug-free core with discrete complete coating layer containing drug
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
- A61K9/2081—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Inorganic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Saccharide Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Cosmetics (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP24354388 | 1988-09-27 |
Publications (1)
Publication Number | Publication Date |
---|---|
NZ230763A true NZ230763A (en) | 1991-10-25 |
Family
ID=17105442
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NZ230763A NZ230763A (en) | 1988-09-27 | 1989-09-25 | Production of granules having a core by spraying the cores with a dispersion of hydroxypropylcellulose, optionally incorporating an active ingredient |
Country Status (11)
Country | Link |
---|---|
US (1) | US5855914A (de) |
EP (1) | EP0361874B1 (de) |
KR (1) | KR0143424B1 (de) |
AT (1) | ATE97317T1 (de) |
AU (1) | AU626584B2 (de) |
CA (1) | CA1338596C (de) |
DE (1) | DE68910773T2 (de) |
DK (1) | DK473889A (de) |
ES (1) | ES2060784T3 (de) |
IE (1) | IE63039B1 (de) |
NZ (1) | NZ230763A (de) |
Families Citing this family (39)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9114374D0 (en) * | 1991-07-03 | 1991-08-21 | Smithkline Beecham Plc | Novel process |
SE9402422D0 (sv) * | 1994-07-08 | 1994-07-08 | Astra Ab | New beads for controlled release and a pharmaceutical preparation containing the same |
SE9600046D0 (sv) * | 1996-01-05 | 1996-01-05 | Astra Ab | New pharmaceutical formulation |
WO1997037638A2 (de) * | 1996-04-04 | 1997-10-16 | L A B Gmbh & Co | Verfahren zur herstellung von gering dosierten freifliessenden und/oder direktkomprimierbaren pulversystemen |
TW580397B (en) * | 1997-05-27 | 2004-03-21 | Takeda Chemical Industries Ltd | Solid preparation |
FR2771291B1 (fr) * | 1997-11-21 | 2000-02-25 | Ethypharm Lab Prod Ethiques | Spheroides, procede de preparation et compositions pharmaceutiques |
FR2771292B1 (fr) * | 1997-11-21 | 2000-02-18 | Ethypharm Lab Prod Ethiques | Spheroides contenant de la tiagabine, procede de preparation et compositions pharmaceutiques |
KR101032289B1 (ko) | 1998-05-18 | 2011-05-06 | 다케다 야쿠힌 고교 가부시키가이샤 | 미세과립 |
EP1561458B1 (de) * | 1998-07-28 | 2010-09-15 | Takeda Pharmaceutical Company Limited | Leicht zerfallende feste Zubereitung |
US6555139B2 (en) | 1999-06-28 | 2003-04-29 | Wockhardt Europe Limited | Preparation of micron-size pharmaceutical particles by microfluidization |
US6245913B1 (en) | 1999-06-30 | 2001-06-12 | Wockhardt Europe Limited | Synthetic procedure for 5-methoxy-2-[(4-methoxy-3,5-dimethyl-2-pyridinyl)-methylthio]-IH-benzimidazole hydrochloride and its conversion to omeprazole |
CA2313504C (en) | 1999-07-12 | 2007-05-29 | Douglas P. Debernardi | Folic acid in solid dosage forms |
FR2796840B1 (fr) * | 1999-07-26 | 2003-06-20 | Ethypharm Lab Prod Ethiques | Comprimes faiblement doses et procede de preparation |
EP1238662B1 (de) * | 2001-03-07 | 2006-05-31 | Dainippon Sumitomo Pharma Co., Ltd. | Verfahren zur Herstellung von Arzneistoffgranulatkörnern, die Arzneistoffgranulatkörner sowie diese enthaltende pharmazeutische Zubereitungen |
US20070059368A1 (en) * | 2005-05-31 | 2007-03-15 | Cherukuri S R | Modified release formulations of anti-irritability drugs |
MY148466A (en) * | 2001-10-26 | 2013-04-30 | Merck Frosst Canada Ltd | Granule formulation |
US20030220351A1 (en) * | 2002-05-24 | 2003-11-27 | Gilbert Gonzales | Enteric coated caffeine tablet |
US20050054611A1 (en) * | 2002-09-13 | 2005-03-10 | Mats Lake | Composition and method for use in intestinal cleansing procedures |
DE602004024960D1 (de) | 2003-01-21 | 2010-02-25 | Nippon Shinyaku Co Ltd | Rasch in der mundhöhle schmelzende tablette |
FR2861990B1 (fr) | 2003-11-10 | 2006-02-10 | Nouveaux Produits Pharma | Comprimes faiblement doses a reseau de polymeres |
US7670624B2 (en) * | 2004-01-29 | 2010-03-02 | Astella Pharma Inc. | Gastrointestinal-specific multiple drug release system |
CA2561700A1 (en) * | 2004-04-16 | 2005-12-15 | Santarus, Inc. | Combination of proton pump inhibitor, buffering agent, and prokinetic agent |
US8715724B2 (en) * | 2004-10-29 | 2014-05-06 | Mayne Pharma International Pty Ltd | Tabletting process |
CA2784881C (en) * | 2005-02-25 | 2016-02-09 | Takeda Pharmaceutical Company Limited | Method for producing granules |
US20090017110A1 (en) * | 2005-05-31 | 2009-01-15 | Capricorn Pharma Inc. | Modified release formulations of anti-irritability drugs |
US11266607B2 (en) * | 2005-08-15 | 2022-03-08 | AbbVie Pharmaceuticals GmbH | Process for the manufacture and use of pancreatin micropellet cores |
WO2008018561A1 (fr) * | 2006-08-11 | 2008-02-14 | Asahi Kasei Chemicals Corporation | Procédé de production de granulé sphérique contenant une substance légèrement hydrosoluble |
MX2009004475A (es) | 2006-10-27 | 2009-08-12 | Univ Missouri | Composiciones que comprenden agentes acido labiles que inhiben la bomba de protones, por lo menos otro agente farmaceuticamente activo y metodos de uso de las misma. |
US20080194307A1 (en) * | 2007-02-13 | 2008-08-14 | Jeff Sanger | Sports-based game of chance |
WO2008114800A2 (en) * | 2007-03-13 | 2008-09-25 | Takeda Pharmaceutical Company Limited | Solid preparation comprising 2- [ [6- [ (3r) -3-amino-1-piperidinyl] -3, 4-dihydro-3-methyl-2, 4-dioxo-1 (2h) -pyrimidinyl] methyl] -4-fluorobenzonitrile |
CA2615137A1 (en) * | 2007-12-17 | 2009-06-17 | Pharmascience Inc. | Single layered controlled release therapeutic system |
US8247440B2 (en) | 2008-02-20 | 2012-08-21 | Curators Of The University Of Missouri | Composition comprising omeprazole, lansoprazole and at least one buffering agent |
US8303868B2 (en) * | 2009-01-26 | 2012-11-06 | Shin-Etsu Chemical Co., Ltd. | Wet granulation tableting method using aqueous dispersion of low-substituted hydroxypropyl cellulose |
CN103096880B (zh) * | 2010-09-13 | 2016-08-24 | 大鹏药品工业株式会社 | 不愉快味道被掩蔽的含药膜包覆的颗粒 |
EP2674149B1 (de) | 2012-06-15 | 2017-10-04 | Shin-Etsu Chemical Co., Ltd. | Verfahren zur Herstellung von Verbundgranulat mit niedrigsubstituierter Hydroxypropylcellulose und Präparat mit schneller Freisetzung |
US20170182070A1 (en) | 2014-10-08 | 2017-06-29 | Mayne Pharma International Pty Ltd. | Controlled Release Doxycycline |
US20170042806A1 (en) | 2015-04-29 | 2017-02-16 | Dexcel Pharma Technologies Ltd. | Orally disintegrating compositions |
US10076494B2 (en) | 2016-06-16 | 2018-09-18 | Dexcel Pharma Technologies Ltd. | Stable orally disintegrating pharmaceutical compositions |
CN110200935B (zh) * | 2019-06-03 | 2021-03-02 | 浙江得恩德制药股份有限公司 | 一种胶体果胶铋胶囊及其制备工艺 |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3664963A (en) * | 1969-10-22 | 1972-05-23 | Balchem Corp | Encapsulation process |
SE426548B (sv) * | 1978-12-05 | 1983-01-31 | Haessle Ab | Fast farmaceutisk beredning innehallande en terapeutiskt effektiv hjertglykosid och en polymer |
JPS5826816A (ja) * | 1981-08-11 | 1983-02-17 | Teisan Seiyaku Kk | 球形顆粒からなる持続性複合顆粒剤 |
DK150008C (da) * | 1981-11-20 | 1987-05-25 | Benzon As Alfred | Fremgangsmaade til fremstilling af et farmaceutisk oralt polydepotpraeparat |
US4568559A (en) * | 1984-02-06 | 1986-02-04 | Biotek, Inc. | Composite core coated microparticles and process of preparing same |
GB8507779D0 (en) * | 1985-03-26 | 1985-05-01 | Fujisawa Pharmaceutical Co | Drug carrier |
GB8518301D0 (en) * | 1985-07-19 | 1985-08-29 | Fujisawa Pharmaceutical Co | Hydrodynamically explosive systems |
US4704285A (en) * | 1985-11-18 | 1987-11-03 | The Dow Chemical Company | Sustained release compositions comprising hydroxypropyl cellulose ethers |
US5026560A (en) * | 1987-01-29 | 1991-06-25 | Takeda Chemical Industries, Ltd. | Spherical granules having core and their production |
JP2536109B2 (ja) * | 1988-12-19 | 1996-09-18 | ライオン株式会社 | 毛髪化粧料 |
-
1989
- 1989-09-25 CA CA000612782A patent/CA1338596C/en not_active Expired - Lifetime
- 1989-09-25 NZ NZ230763A patent/NZ230763A/xx unknown
- 1989-09-26 IE IE307589A patent/IE63039B1/en not_active IP Right Cessation
- 1989-09-26 DK DK473889A patent/DK473889A/da not_active Application Discontinuation
- 1989-09-26 EP EP89309802A patent/EP0361874B1/de not_active Expired - Lifetime
- 1989-09-26 DE DE89309802T patent/DE68910773T2/de not_active Expired - Lifetime
- 1989-09-26 ES ES89309802T patent/ES2060784T3/es not_active Expired - Lifetime
- 1989-09-26 AT AT89309802T patent/ATE97317T1/de not_active IP Right Cessation
- 1989-09-26 AU AU42332/89A patent/AU626584B2/en not_active Expired
- 1989-09-27 KR KR1019890013906A patent/KR0143424B1/ko not_active IP Right Cessation
-
1994
- 1994-08-09 US US08/287,424 patent/US5855914A/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
EP0361874A3 (de) | 1991-01-30 |
AU626584B2 (en) | 1992-08-06 |
ATE97317T1 (de) | 1993-12-15 |
US5855914A (en) | 1999-01-05 |
IE893075L (en) | 1990-03-27 |
DK473889D0 (da) | 1989-09-26 |
IE63039B1 (en) | 1995-03-22 |
EP0361874B1 (de) | 1993-11-18 |
DE68910773D1 (de) | 1993-12-23 |
CA1338596C (en) | 1996-09-17 |
KR0143424B1 (ko) | 1998-07-15 |
ES2060784T3 (es) | 1994-12-01 |
DE68910773T2 (de) | 1994-05-11 |
DK473889A (da) | 1990-03-28 |
EP0361874A2 (de) | 1990-04-04 |
AU4233289A (en) | 1990-04-05 |
KR900004325A (ko) | 1990-04-12 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RENW | Renewal (renewal fees accepted) |