NZ222593A - Cephalosporin derivatives and pharmaceutical compositions - Google Patents

Cephalosporin derivatives and pharmaceutical compositions

Info

Publication number
NZ222593A
NZ222593A NZ222593A NZ22259387A NZ222593A NZ 222593 A NZ222593 A NZ 222593A NZ 222593 A NZ222593 A NZ 222593A NZ 22259387 A NZ22259387 A NZ 22259387A NZ 222593 A NZ222593 A NZ 222593A
Authority
NZ
New Zealand
Prior art keywords
pharmaceutical compositions
image
cephalosporin derivatives
derivatives
cooh
Prior art date
Application number
NZ222593A
Inventor
Dominique Olliero
Bernard Labeeuw
Gilles Roche
Ali Salhi
Original Assignee
Sanofi Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Sa filed Critical Sanofi Sa
Publication of NZ222593A publication Critical patent/NZ222593A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/26—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group
    • C07D501/34—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group with the 7-amino radical acylated by carboxylic acids containing hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Derivatives corresponding to the general formula: <IMAGE> in which: - R1, R2 and R3 denote H, or R1 and R2 denote H or CH3 and R3 = COOH or else <IMAGE> form a cyclobutyl group and R3 = COOH; - A and B are different and occupy the meta and para positions of the benzene nucleus; one denotes a hydroxyl group and the other is chosen from the groups <IMAGE> and the pharmaceutically acceptable salts and esters of the said derivatives. Use in therapeutics.
NZ222593A 1986-11-20 1987-11-18 Cephalosporin derivatives and pharmaceutical compositions NZ222593A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8616175A FR2607135B1 (en) 1986-11-20 1986-11-20 NOVEL CEPHALOSPORINS DERIVATIVES WITH IMPROVED PHARMACOKINETICS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

Publications (1)

Publication Number Publication Date
NZ222593A true NZ222593A (en) 1989-04-26

Family

ID=9341024

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ222593A NZ222593A (en) 1986-11-20 1987-11-18 Cephalosporin derivatives and pharmaceutical compositions

Country Status (13)

Country Link
EP (1) EP0269512B1 (en)
JP (1) JPS63141985A (en)
KR (1) KR880006251A (en)
AT (1) ATE67208T1 (en)
DE (1) DE3772936D1 (en)
DK (1) DK611987A (en)
ES (1) ES2038997T3 (en)
FR (1) FR2607135B1 (en)
GR (1) GR3002769T3 (en)
IL (1) IL84539A (en)
NZ (1) NZ222593A (en)
PT (1) PT86164B (en)
ZA (1) ZA878710B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2621589B1 (en) * 1987-10-08 1990-03-02 Sanofi Sa CEPHALOSPORIN DERIVATIVES WITH IMPROVED PHARMACOKINETICS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
US5189157A (en) * 1987-06-16 1993-02-23 Hoffmann La Roche Inc. Antibacterial cephalosporin compounds

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2546520B1 (en) * 1983-05-27 1985-08-30 Sanofi Sa NOVEL ANTIBIOTIC COMPOUNDS DERIVED FROM CEPHALOSPORINS
FR2570702B1 (en) * 1984-09-27 1987-01-09 Sanofi Sa CEPHALOSPORIN DERIVATIVES, PROCESSES FOR OBTAINING THEM AND THEIR APPLICATION AS ANTIBIOTICS

Also Published As

Publication number Publication date
EP0269512A1 (en) 1988-06-01
AU8134887A (en) 1988-05-26
ES2038997T3 (en) 1993-08-16
ZA878710B (en) 1988-05-20
DK611987D0 (en) 1987-11-20
EP0269512B1 (en) 1991-09-11
DK611987A (en) 1988-05-21
PT86164B (en) 1990-11-20
FR2607135B1 (en) 1989-04-28
FR2607135A1 (en) 1988-05-27
DE3772936D1 (en) 1991-10-17
GR3002769T3 (en) 1993-01-25
KR880006251A (en) 1988-07-22
JPS63141985A (en) 1988-06-14
PT86164A (en) 1987-12-01
ATE67208T1 (en) 1991-09-15
IL84539A (en) 1992-12-01
IL84539A0 (en) 1988-04-29
AU597748B2 (en) 1990-06-07

Similar Documents

Publication Publication Date Title
RU94028109A (en) NEW SUBSTITUTED SALICYL ACIDS, METHOD OF THEIR RECEIVING
FI894364A0 (en) STEROIDER MED EN 19,11B, BRYGGA, FRAMSTAELLNING AV OCH PHARMACEUTICAL COMPOSITION INNEHAOLLANDE DESAMMA.
AU1178588A (en) New 19-norsteroids substituted at the 7-position, their preparation, their application as drugs and the pharmaceutical compositions containing them
DE69032681D1 (en) Cephalosporins and their homologues, processes for their preparation and pharmaceutical preparations
ES8705891A1 (en) Cephalosporin antibiotics
ES8505352A1 (en) Mercapto-imidazole derivatives, their preparation, mercapto-imidazole derivatives for the treatment of inflammatory diseases and their pharmaceutical compositions.
SE8301178L (en) NEW CEPHALOSPORIN DERIVATIVES AND PROCEDURES FOR PRODUCING THEREOF
ES8304062A1 (en) Derivatives of 4-aminoethoxy-5-isopropyl-2-methyl phenol, process for their preparation and their use as medicines.
NZ222593A (en) Cephalosporin derivatives and pharmaceutical compositions
ES8406492A1 (en) Cephalosporin derivatives.
ATE54148T1 (en) NEW CEPHALOSPORINS AND PROCESSES FOR THEIR PRODUCTION.
ES8308331A1 (en) Cephalosporin derivatives substituted in position 3 with a thiomethylheterocyclic group, process for their preparation and pharmaceutical compositions containing them.
ATE18211T1 (en) QUINOLINEACETIC ACIDS AND PHARMACEUTICAL PREPARATIONS CONTAINING THEM.
DE68919433D1 (en) Cephalosporins, processes for their preparation, intermediates and pharmaceutical preparations.
ES8800162A1 (en) Esters of derivatives of 2-alpha-hydroxy-substituted 4-hydroxy-3-quinoline carboxylic acid, their preparation, their use as medicaments and compositions containing them.
GB2282810A (en) Process for the preparation of clavulanic acid
ES2005778A6 (en) Diisobutylxanthine derivatives substituted in position 7 which are useful as bronchodilators, process for their preparation and pharmaceutical composition containing them
ES8704163A1 (en) Cephem derivatives.
NZ223022A (en) Dibenzo(be)oxepineacetic acid derivatives and pharmaceutical compositions