NZ216829A - Distamycin derivatives and pharmaceutical compositions - Google Patents

Distamycin derivatives and pharmaceutical compositions

Info

Publication number
NZ216829A
NZ216829A NZ216829A NZ21682986A NZ216829A NZ 216829 A NZ216829 A NZ 216829A NZ 216829 A NZ216829 A NZ 216829A NZ 21682986 A NZ21682986 A NZ 21682986A NZ 216829 A NZ216829 A NZ 216829A
Authority
NZ
New Zealand
Prior art keywords
pharmaceutical compositions
distamycin derivatives
distamycin
derivatives
pharmaceutical
Prior art date
Application number
NZ216829A
Other languages
English (en)
Inventor
F Arcamone
N Mongelli
S Penco
Original Assignee
Erba Farmitalia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB858517922A external-priority patent/GB8517922D0/en
Priority claimed from GB868613594A external-priority patent/GB8613594D0/en
Application filed by Erba Farmitalia filed Critical Erba Farmitalia
Publication of NZ216829A publication Critical patent/NZ216829A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/26Acyclic or carbocyclic radicals, substituted by hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Virology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Polyamides (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
NZ216829A 1985-07-16 1986-07-14 Distamycin derivatives and pharmaceutical compositions NZ216829A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB858517922A GB8517922D0 (en) 1985-07-16 1985-07-16 Carboxamido derivatives
GB868613594A GB8613594D0 (en) 1986-06-04 1986-06-04 Poly-4-aminopyrrole-2-carboxamido derivatives

Publications (1)

Publication Number Publication Date
NZ216829A true NZ216829A (en) 1989-03-29

Family

ID=26289538

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ216829A NZ216829A (en) 1985-07-16 1986-07-14 Distamycin derivatives and pharmaceutical compositions

Country Status (26)

Country Link
JP (1) JPH0780843B2 (nl)
KR (1) KR930010496B1 (nl)
CN (1) CN1018825B (nl)
AT (1) AT387013B (nl)
AU (1) AU587841B2 (nl)
BE (1) BE905110A (nl)
CA (1) CA1285934C (nl)
CH (1) CH674206A5 (nl)
CS (1) CS276981B6 (nl)
DE (1) DE3623880A1 (nl)
DK (1) DK335986A (nl)
ES (1) ES2000502A6 (nl)
FI (1) FI83640C (nl)
FR (1) FR2585018B1 (nl)
GB (1) GB2178036B (nl)
GR (1) GR861841B (nl)
HU (1) HU205949B (nl)
IE (1) IE59073B1 (nl)
IL (1) IL79402A (nl)
IT (1) IT1196488B (nl)
NL (1) NL8601837A (nl)
NO (1) NO168826C (nl)
NZ (1) NZ216829A (nl)
PH (1) PH24714A (nl)
PT (1) PT82984B (nl)
SE (1) SE468642B (nl)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN85103908A (zh) * 1985-07-16 1986-11-05 法米塔利·卡洛·埃尔巴有限公司 制备4′-表多克索红菌素的新方法
GB8906709D0 (en) * 1989-03-23 1989-05-10 Creighton Andrew M Acryloyl substituted pyrrole derivatives
IT1243389B (it) * 1990-11-22 1994-06-10 Menarini Farma Ind Derivati poliaminopirrolcarbossiamidici, processi di preparazione e composizioni farmaceutiche che li contengono.
AU1224392A (en) * 1991-02-06 1992-09-07 Synphar Laboratories, Inc. Oligopeptide antiretroviral agents
IT1247878B (it) * 1991-02-15 1995-01-05 Menarini Farma Ind Derivati poli-4-aminopirrol-2-carbossiamidici,processi di preparazione e composizioni farmaceutiche che li contengono
GB2260134A (en) * 1991-10-04 1993-04-07 Erba Carlo Spa Derivatives of poly-5-amino-3-carboxy-1-methyl compounds
IT1262921B (it) * 1992-01-10 1996-07-22 Federico Arcamone Agenti antitumorali analoghi di oligopeptidi pirrol-amidinici retroversi processi di preparazione e prodotti farmaceutici che li contengono
GB9416005D0 (en) * 1994-08-08 1994-09-28 Erba Carlo Spa Peptidic compounds analogous to distamycin a and process for their preparation
CA2204648A1 (en) * 1995-09-12 1997-03-20 Akira Mihara Uch15 compounds
US6165980A (en) * 1996-02-02 2000-12-26 Pharmacia & Upjohn S.P.A. Distamycin derivatives, process for preparing them, and their use as antitumor and antiviral agents
GB9615692D0 (en) * 1996-07-25 1996-09-04 Pharmacia Spa Acryloyl substituted distamycin derivatives, process for preparing them, and their use as antitumor and antiviral agents
GB0011059D0 (en) 2000-05-08 2000-06-28 Pharmacia & Upjohn Spa Use of substituted acryloyl distamycin derivatives in the treatment of tumours associated with high levels of glutathione
GB0015447D0 (en) 2000-06-23 2000-08-16 Pharmacia & Upjohn Spa Combined therapy against tumors comprising substituted acryloyl derivates and alkylating agents
GB0015446D0 (en) 2000-06-23 2000-08-16 Pharmacia & Upjohn Spa Combined therapy against tumors comprising substituted acryloyl distamycin derivates,taxanes and/or antimetabolites
GB0016447D0 (en) 2000-07-04 2000-08-23 Pharmacia & Upjohn Spa Process for preparing distamycin derivatives
US6969592B2 (en) 2001-09-26 2005-11-29 Pharmacia Italia S.P.A. Method for predicting the sensitivity to chemotherapy

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR86210E (nl) * 1963-04-04 1966-03-23
BR6461040D0 (pt) * 1963-07-26 1973-08-02 Farmaceutici Italia Processo para preparar novos derivados de pirrol
DE1795539A1 (de) * 1963-07-26 1972-01-13 Farmaceutici Italia Verfahren zur Herstellung von neuen Pyrrolderivaten und ihren Salzen
BE666612A (nl) * 1963-07-26 1965-11-03
NL130086C (nl) * 1964-07-14 1970-06-15
CN85103908A (zh) * 1985-07-16 1986-11-05 法米塔利·卡洛·埃尔巴有限公司 制备4′-表多克索红菌素的新方法

Also Published As

Publication number Publication date
AT387013B (de) 1988-11-25
DE3623880A1 (de) 1987-01-29
BE905110A (fr) 1987-01-15
GB2178036B (en) 1989-08-16
FR2585018B1 (fr) 1989-07-13
JPH0780843B2 (ja) 1995-08-30
IL79402A0 (en) 1986-10-31
IL79402A (en) 1991-06-10
JPS6277362A (ja) 1987-04-09
AU6020286A (en) 1987-01-22
PH24714A (en) 1990-10-01
FI83640B (fi) 1991-04-30
NO862860L (no) 1987-01-19
PT82984B (pt) 1989-01-30
IT8621125A1 (it) 1988-01-15
NO168826C (no) 1992-04-08
AU587841B2 (en) 1989-08-31
IE59073B1 (en) 1994-01-12
DK335986D0 (da) 1986-07-15
CN86104787A (zh) 1987-02-18
NO168826B (no) 1991-12-30
CA1285934C (en) 1991-07-09
FI83640C (fi) 1991-08-12
SE468642B (sv) 1993-02-22
PT82984A (en) 1986-08-01
IT8621125A0 (it) 1986-07-15
CH674206A5 (nl) 1990-05-15
DK335986A (da) 1987-01-17
SE8603098D0 (sv) 1986-07-11
CS276981B6 (en) 1992-11-18
SE8603098L (sv) 1987-01-17
KR930010496B1 (ko) 1993-10-25
ATA188886A (de) 1988-04-15
FI862959A0 (fi) 1986-07-16
FI862959A (fi) 1987-01-17
NO862860D0 (no) 1986-07-15
HUT43088A (en) 1987-09-28
FR2585018A1 (fr) 1987-01-23
KR870001201A (ko) 1987-03-12
ES2000502A6 (es) 1988-03-01
HU205949B (en) 1992-07-28
NL8601837A (nl) 1987-02-16
IT1196488B (it) 1988-11-16
CS8605412A2 (en) 1991-03-12
CN1018825B (zh) 1992-10-28
IE861875L (en) 1987-01-16
GR861841B (en) 1986-11-18
GB2178036A (en) 1987-02-04
GB8617292D0 (en) 1986-08-20

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