FR2585018B1 - Poly-4-aminopyrrole-2-carboxamides et derives, procede pour leur preparation et leurs utilisations therapeutiques - Google Patents
Poly-4-aminopyrrole-2-carboxamides et derives, procede pour leur preparation et leurs utilisations therapeutiquesInfo
- Publication number
- FR2585018B1 FR2585018B1 FR868610294A FR8610294A FR2585018B1 FR 2585018 B1 FR2585018 B1 FR 2585018B1 FR 868610294 A FR868610294 A FR 868610294A FR 8610294 A FR8610294 A FR 8610294A FR 2585018 B1 FR2585018 B1 FR 2585018B1
- Authority
- FR
- France
- Prior art keywords
- aminopyrrole
- carboxamides
- poly
- derivatives
- preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/26—Acyclic or carbocyclic radicals, substituted by hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Virology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
- Polyamides (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB858517922A GB8517922D0 (en) | 1985-07-16 | 1985-07-16 | Carboxamido derivatives |
GB868613594A GB8613594D0 (en) | 1986-06-04 | 1986-06-04 | Poly-4-aminopyrrole-2-carboxamido derivatives |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2585018A1 FR2585018A1 (fr) | 1987-01-23 |
FR2585018B1 true FR2585018B1 (fr) | 1989-07-13 |
Family
ID=26289538
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR868610294A Expired FR2585018B1 (fr) | 1985-07-16 | 1986-07-15 | Poly-4-aminopyrrole-2-carboxamides et derives, procede pour leur preparation et leurs utilisations therapeutiques |
Country Status (26)
Country | Link |
---|---|
JP (1) | JPH0780843B2 (nl) |
KR (1) | KR930010496B1 (nl) |
CN (1) | CN1018825B (nl) |
AT (1) | AT387013B (nl) |
AU (1) | AU587841B2 (nl) |
BE (1) | BE905110A (nl) |
CA (1) | CA1285934C (nl) |
CH (1) | CH674206A5 (nl) |
CS (1) | CS276981B6 (nl) |
DE (1) | DE3623880A1 (nl) |
DK (1) | DK335986A (nl) |
ES (1) | ES2000502A6 (nl) |
FI (1) | FI83640C (nl) |
FR (1) | FR2585018B1 (nl) |
GB (1) | GB2178036B (nl) |
GR (1) | GR861841B (nl) |
HU (1) | HU205949B (nl) |
IE (1) | IE59073B1 (nl) |
IL (1) | IL79402A (nl) |
IT (1) | IT1196488B (nl) |
NL (1) | NL8601837A (nl) |
NO (1) | NO168826C (nl) |
NZ (1) | NZ216829A (nl) |
PH (1) | PH24714A (nl) |
PT (1) | PT82984B (nl) |
SE (1) | SE468642B (nl) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN85103908A (zh) * | 1985-07-16 | 1986-11-05 | 法米塔利·卡洛·埃尔巴有限公司 | 制备4′-表多克索红菌素的新方法 |
GB8906709D0 (en) * | 1989-03-23 | 1989-05-10 | Creighton Andrew M | Acryloyl substituted pyrrole derivatives |
IT1243389B (it) * | 1990-11-22 | 1994-06-10 | Menarini Farma Ind | Derivati poliaminopirrolcarbossiamidici, processi di preparazione e composizioni farmaceutiche che li contengono. |
AU1224392A (en) * | 1991-02-06 | 1992-09-07 | Synphar Laboratories, Inc. | Oligopeptide antiretroviral agents |
IT1247878B (it) * | 1991-02-15 | 1995-01-05 | Menarini Farma Ind | Derivati poli-4-aminopirrol-2-carbossiamidici,processi di preparazione e composizioni farmaceutiche che li contengono |
GB2260134A (en) * | 1991-10-04 | 1993-04-07 | Erba Carlo Spa | Derivatives of poly-5-amino-3-carboxy-1-methyl compounds |
IT1262921B (it) * | 1992-01-10 | 1996-07-22 | Federico Arcamone | Agenti antitumorali analoghi di oligopeptidi pirrol-amidinici retroversi processi di preparazione e prodotti farmaceutici che li contengono |
GB9416005D0 (en) * | 1994-08-08 | 1994-09-28 | Erba Carlo Spa | Peptidic compounds analogous to distamycin a and process for their preparation |
CA2204648A1 (en) * | 1995-09-12 | 1997-03-20 | Akira Mihara | Uch15 compounds |
US6165980A (en) * | 1996-02-02 | 2000-12-26 | Pharmacia & Upjohn S.P.A. | Distamycin derivatives, process for preparing them, and their use as antitumor and antiviral agents |
GB9615692D0 (en) * | 1996-07-25 | 1996-09-04 | Pharmacia Spa | Acryloyl substituted distamycin derivatives, process for preparing them, and their use as antitumor and antiviral agents |
GB0011059D0 (en) | 2000-05-08 | 2000-06-28 | Pharmacia & Upjohn Spa | Use of substituted acryloyl distamycin derivatives in the treatment of tumours associated with high levels of glutathione |
GB0015447D0 (en) | 2000-06-23 | 2000-08-16 | Pharmacia & Upjohn Spa | Combined therapy against tumors comprising substituted acryloyl derivates and alkylating agents |
GB0015446D0 (en) | 2000-06-23 | 2000-08-16 | Pharmacia & Upjohn Spa | Combined therapy against tumors comprising substituted acryloyl distamycin derivates,taxanes and/or antimetabolites |
GB0016447D0 (en) | 2000-07-04 | 2000-08-23 | Pharmacia & Upjohn Spa | Process for preparing distamycin derivatives |
US6969592B2 (en) | 2001-09-26 | 2005-11-29 | Pharmacia Italia S.P.A. | Method for predicting the sensitivity to chemotherapy |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR86210E (nl) * | 1963-04-04 | 1966-03-23 | ||
BR6461040D0 (pt) * | 1963-07-26 | 1973-08-02 | Farmaceutici Italia | Processo para preparar novos derivados de pirrol |
DE1795539A1 (de) * | 1963-07-26 | 1972-01-13 | Farmaceutici Italia | Verfahren zur Herstellung von neuen Pyrrolderivaten und ihren Salzen |
BE666612A (nl) * | 1963-07-26 | 1965-11-03 | ||
NL130086C (nl) * | 1964-07-14 | 1970-06-15 | ||
CN85103908A (zh) * | 1985-07-16 | 1986-11-05 | 法米塔利·卡洛·埃尔巴有限公司 | 制备4′-表多克索红菌素的新方法 |
-
1986
- 1986-07-11 AT AT0188886A patent/AT387013B/de not_active IP Right Cessation
- 1986-07-11 SE SE8603098A patent/SE468642B/sv not_active IP Right Cessation
- 1986-07-14 IE IE187586A patent/IE59073B1/en not_active IP Right Cessation
- 1986-07-14 IL IL79402A patent/IL79402A/xx not_active IP Right Cessation
- 1986-07-14 HU HU862904A patent/HU205949B/hu not_active IP Right Cessation
- 1986-07-14 NZ NZ216829A patent/NZ216829A/xx unknown
- 1986-07-14 NL NL8601837A patent/NL8601837A/nl not_active Application Discontinuation
- 1986-07-14 AU AU60202/86A patent/AU587841B2/en not_active Ceased
- 1986-07-14 ES ES8600290A patent/ES2000502A6/es not_active Expired
- 1986-07-15 FR FR868610294A patent/FR2585018B1/fr not_active Expired
- 1986-07-15 IT IT21125/86A patent/IT1196488B/it active
- 1986-07-15 PT PT82984A patent/PT82984B/pt not_active IP Right Cessation
- 1986-07-15 GR GR861841A patent/GR861841B/el unknown
- 1986-07-15 JP JP61164879A patent/JPH0780843B2/ja not_active Expired - Lifetime
- 1986-07-15 KR KR1019860005715A patent/KR930010496B1/ko not_active IP Right Cessation
- 1986-07-15 CH CH2820/86A patent/CH674206A5/de not_active IP Right Cessation
- 1986-07-15 BE BE0/216924A patent/BE905110A/fr not_active IP Right Cessation
- 1986-07-15 DE DE3623880A patent/DE3623880A1/de not_active Withdrawn
- 1986-07-15 PH PH34014A patent/PH24714A/en unknown
- 1986-07-15 CA CA000513760A patent/CA1285934C/en not_active Expired - Fee Related
- 1986-07-15 NO NO862860A patent/NO168826C/no unknown
- 1986-07-15 DK DK335986A patent/DK335986A/da not_active Application Discontinuation
- 1986-07-16 CS CS865412A patent/CS276981B6/cs unknown
- 1986-07-16 GB GB8617292A patent/GB2178036B/en not_active Expired
- 1986-07-16 FI FI862959A patent/FI83640C/fi not_active IP Right Cessation
- 1986-07-16 CN CN86104787A patent/CN1018825B/zh not_active Expired
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
TP | Transmission of property | ||
CD | Change of name or company name | ||
TP | Transmission of property | ||
ST | Notification of lapse |