NZ189297A - Pgs inhibitor containing sterol glycosides - Google Patents
Pgs inhibitor containing sterol glycosidesInfo
- Publication number
- NZ189297A NZ189297A NZ189297A NZ18929779A NZ189297A NZ 189297 A NZ189297 A NZ 189297A NZ 189297 A NZ189297 A NZ 189297A NZ 18929779 A NZ18929779 A NZ 18929779A NZ 189297 A NZ189297 A NZ 189297A
- Authority
- NZ
- New Zealand
- Prior art keywords
- medicament according
- pgs
- formula
- glucoside
- compounds
- Prior art date
Links
- 229930182470 glycoside Natural products 0.000 title claims description 9
- 229930182558 Sterol Natural products 0.000 title claims description 8
- 235000003702 sterols Nutrition 0.000 title claims description 8
- 239000003112 inhibitor Substances 0.000 title description 9
- -1 sterol glycosides Chemical class 0.000 title description 9
- 150000001875 compounds Chemical class 0.000 claims description 29
- 230000000694 effects Effects 0.000 claims description 17
- 239000003814 drug Substances 0.000 claims description 12
- 239000002245 particle Substances 0.000 claims description 11
- 150000002148 esters Chemical class 0.000 claims description 10
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- WQLVFSAGQJTQCK-UHFFFAOYSA-N diosgenin Natural products CC1C(C2(CCC3C4(C)CCC(O)CC4=CCC3C2C2)C)C2OC11CCC(C)CO1 WQLVFSAGQJTQCK-UHFFFAOYSA-N 0.000 claims description 8
- DWCSNWXARWMZTG-UHFFFAOYSA-N Trigonegenin A Natural products CC1C(C2(CCC3C4(C)CCC(O)C=C4CCC3C2C2)C)C2OC11CCC(C)CO1 DWCSNWXARWMZTG-UHFFFAOYSA-N 0.000 claims description 7
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- 229930182478 glucoside Natural products 0.000 claims description 7
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- WQLVFSAGQJTQCK-VKROHFNGSA-N diosgenin Chemical compound O([C@@H]1[C@@H]([C@]2(CC[C@@H]3[C@@]4(C)CC[C@H](O)CC4=CC[C@H]3[C@@H]2C1)C)[C@@H]1C)[C@]11CC[C@@H](C)CO1 WQLVFSAGQJTQCK-VKROHFNGSA-N 0.000 claims description 6
- 125000004435 hydrogen atom Chemical group [H]* 0.000 claims description 6
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims description 6
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- 239000013543 active substance Substances 0.000 claims description 3
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 claims description 3
- 125000000219 ethylidene group Chemical group [H]C(=[*])C([H])([H])[H] 0.000 claims description 3
- 125000000325 methylidene group Chemical group [H]C([H])=* 0.000 claims description 3
- 239000002599 prostaglandin synthase inhibitor Substances 0.000 claims description 3
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- XYTLYKGXLMKYMV-UHFFFAOYSA-N 14alpha-methylzymosterol Natural products CC12CCC(O)CC1CCC1=C2CCC2(C)C(C(CCC=C(C)C)C)CCC21C XYTLYKGXLMKYMV-UHFFFAOYSA-N 0.000 claims description 2
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Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19772759171 DE2759171A1 (de) | 1977-12-31 | 1977-12-31 | Arzneimittel mit wirkung als prostaglandinsynthetaseninhibitor |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NZ189297A true NZ189297A (en) | 1984-10-19 |
Family
ID=6027873
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NZ189297A NZ189297A (en) | 1977-12-31 | 1979-01-04 | Pgs inhibitor containing sterol glycosides |
Country Status (19)
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2926463A1 (de) * | 1978-07-05 | 1980-01-24 | Roecar Holdings Nv | Spiroketaline und ihre verwendung |
| JPS5874619A (ja) * | 1981-10-29 | 1983-05-06 | Nippon Shinyaku Co Ltd | リポソ−ム及びその製法 |
| IE54837B1 (en) | 1982-04-19 | 1990-02-28 | Roecar Holdings Nv | Extract of plants of the family of hypoxidaceae for treatment of cancer |
| US4602003A (en) * | 1982-05-17 | 1986-07-22 | Medical Research Foundation Of Oregon | Synthetic compounds to inhibit intestinal absorption of cholesterol in the treatment of hypercholesterolemia |
| US4602005A (en) * | 1982-05-17 | 1986-07-22 | Medical Research Foundation Of Oregon | Tigogenin cellobioside for treating hypercholesterolemia and atherosclerosis |
| DE3401178A1 (de) * | 1984-01-14 | 1985-07-18 | Roecar Holdings (Netherlands Antilles) N.V., Willemstad, Curacao, Niederländische Antillen | Verwendung von phytosterolglykosiden zur behandlung erhoehter 5(6)(alpha)-epoxicholesterolspiegel |
| DE3416112A1 (de) * | 1984-04-30 | 1985-10-31 | Roecar Holdings (Netherlands Antilles) N.V., Willemstad, Curacao, Niederländische Antillen | Verwendung von sterolinen und spiroketalinen als lipoxygenaseregulatoren |
| DE3829641A1 (de) * | 1988-09-01 | 1990-03-15 | Roecar Holdings Nv | Transdermal anwendbare pharmazeutische zubereitungen mit sterolinen und/oder spiroketalinen |
| DE3829640C1 (enrdf_load_stackoverflow) * | 1988-09-01 | 1990-04-26 | Roecar Holdings (Netherlands Antilles) N.V., Willemstad, Curacao, Niederlaendische Antillen, Nl | |
| DE3829643A1 (de) * | 1988-09-01 | 1990-03-15 | Roecar Holdings Nv | Phyto- und zoosterole und deren derivate mit verbesserter wasserloeslichkeit |
| US5166194A (en) * | 1988-09-01 | 1992-11-24 | Roecar Holdings | Transdermally applicable pharmaceutical preparations having a pharmaceutically usable glycoside content |
| DE3838716A1 (de) * | 1988-11-15 | 1990-05-17 | Kanoldt Arzneimittel Gmbh | Arzneimittelzubereitung aus esterderivaten des hecogenins und dessen verwendung zur behandlung von benigner prostatahyperplasie |
| US5502038A (en) * | 1993-06-21 | 1996-03-26 | Medical Research Foundation Of Oregon | Cholesterol sequestrant glycosides that inhibit intestinal cholesterol absorption |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IE35018B1 (en) * | 1970-03-18 | 1975-10-15 | Liebenberg R W | Therapeutic agent |
| US3966918A (en) * | 1973-12-12 | 1976-06-29 | Nippon Shinyaku Co., Ltd. | Method of preparing aqueous solutions of sterol glycosides and their ester derivatives |
| JPS51118817A (en) * | 1975-04-08 | 1976-10-19 | Nippon Shinyaku Co Ltd | A process for preparing absorbable steroid glycoside pharmaceutical |
-
1977
- 1977-12-31 DE DE19772759171 patent/DE2759171A1/de active Granted
-
1978
- 1978-12-28 ES ES476443A patent/ES476443A1/es not_active Expired
- 1978-12-28 AR AR274988A patent/AR223334A1/es active
- 1978-12-28 ZA ZA787399A patent/ZA787399B/xx unknown
- 1978-12-29 DK DK587778A patent/DK587778A/da not_active Application Discontinuation
- 1978-12-29 BE BE192687A patent/BE873222A/xx not_active IP Right Cessation
- 1978-12-29 AU AU43024/78A patent/AU516933B2/en not_active Expired
- 1978-12-29 FR FR7836823A patent/FR2425859A1/fr active Granted
- 1978-12-29 PT PT69012A patent/PT69012A/pt unknown
- 1978-12-29 CA CA318,817A patent/CA1113006A/en not_active Expired
- 1978-12-29 IL IL56345A patent/IL56345A/xx not_active IP Right Cessation
- 1978-12-29 LU LU80739A patent/LU80739A1/de unknown
- 1978-12-29 JP JP16443078A patent/JPS54101436A/ja active Pending
- 1978-12-29 IT IT52493/78A patent/IT1109336B/it active
- 1978-12-29 CH CH1330878A patent/CH637829A5/de not_active IP Right Cessation
- 1978-12-29 NL NL7812656A patent/NL7812656A/xx not_active Application Discontinuation
- 1978-12-29 SE SE7813443A patent/SE466683B/sv not_active IP Right Cessation
- 1978-12-29 GB GB7850259A patent/GB2039217B/en not_active Expired
-
1979
- 1979-01-04 NZ NZ189297A patent/NZ189297A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU516933B2 (en) | 1981-07-02 |
| ZA787399B (en) | 1980-01-30 |
| DK587778A (da) | 1979-07-01 |
| DE2759171A1 (de) | 1979-07-12 |
| GB2039217A (en) | 1980-08-06 |
| IL56345A0 (en) | 1979-03-12 |
| PT69012A (pt) | 1979-01-01 |
| JPS54101436A (en) | 1979-08-10 |
| SE7813443L (sv) | 1979-07-01 |
| FR2425859B1 (enrdf_load_stackoverflow) | 1983-04-08 |
| DE2759171C2 (enrdf_load_stackoverflow) | 1990-10-25 |
| IL56345A (en) | 1984-11-30 |
| AU4302478A (en) | 1979-07-05 |
| CA1113006A (en) | 1981-11-24 |
| SE466683B (sv) | 1992-03-23 |
| AR223334A1 (es) | 1981-08-14 |
| GB2039217B (en) | 1982-08-04 |
| ES476443A1 (es) | 1979-10-16 |
| IT1109336B (it) | 1985-12-16 |
| CH637829A5 (de) | 1983-08-31 |
| NL7812656A (nl) | 1979-07-03 |
| BE873222A (fr) | 1979-06-29 |
| IT7852493A0 (it) | 1978-12-29 |
| FR2425859A1 (fr) | 1979-12-14 |
| LU80739A1 (de) | 1980-01-22 |
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