NO995108L - 2-okso-1-azetidinsulfonsyrederivater som potente <beta>-laktamase inhibitorer - Google Patents
2-okso-1-azetidinsulfonsyrederivater som potente <beta>-laktamase inhibitorerInfo
- Publication number
- NO995108L NO995108L NO995108A NO995108A NO995108L NO 995108 L NO995108 L NO 995108L NO 995108 A NO995108 A NO 995108A NO 995108 A NO995108 A NO 995108A NO 995108 L NO995108 L NO 995108L
- Authority
- NO
- Norway
- Prior art keywords
- oxo
- sulfonic acid
- acid derivatives
- potent
- beta
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D419/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen, oxygen, and sulfur atoms as the only ring hetero atoms
- C07D419/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen, oxygen, and sulfur atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Oncology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/840,608 US5888998A (en) | 1997-04-24 | 1997-04-24 | 2-oxo-1-azetidine sulfonic acid derivatives as potent β-lactamase inhibitors |
| PCT/IB1998/000622 WO1998047895A1 (en) | 1997-04-24 | 1998-04-23 | 2-OXO-1-AZETIDINE SULFONIC ACID DERIVATIVES AS POTENT β-LACTAMASE INHIBITORS |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO995108D0 NO995108D0 (no) | 1999-10-20 |
| NO995108L true NO995108L (no) | 1999-10-20 |
Family
ID=25282793
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO995108A NO995108L (no) | 1997-04-24 | 1999-10-20 | 2-okso-1-azetidinsulfonsyrederivater som potente <beta>-laktamase inhibitorer |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US5888998A (https=) |
| EP (1) | EP0979229B1 (https=) |
| JP (1) | JP2001521549A (https=) |
| KR (1) | KR20010020181A (https=) |
| AU (1) | AU740446B2 (https=) |
| CA (1) | CA2287219C (https=) |
| DE (1) | DE69808901T2 (https=) |
| HU (1) | HUP0001269A3 (https=) |
| NO (1) | NO995108L (https=) |
| WO (1) | WO1998047895A1 (https=) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20010002705A (ko) * | 1999-06-17 | 2001-01-15 | 고두모 | 신규 티아졸 초산의 반응성 포스페이트 유도체의 제조방법 |
| US6916803B2 (en) * | 2000-09-14 | 2005-07-12 | Pantherix, Ltd. | 3-(Heteroaryl acetamido)-2-oxo-azetidine-1-sulfonic acids derivatives as antibacterial agents |
| WO2007065288A2 (en) | 2005-12-07 | 2007-06-14 | Basilea Pharmaceutica Ag | Useful combinations of monobactam antibiotics with beta-lactamase inhibitors |
| EP2124942B1 (en) * | 2007-03-23 | 2016-04-27 | Basilea Pharmaceutica AG | Combination medicaments for treating bacterial infections |
| CA2807546C (en) | 2010-08-10 | 2022-08-23 | Rempex Pharmaceuticals, Inc. | Cyclic boronic acid ester derivatives and therapeutic uses thereof |
| US8806158B2 (en) | 2010-09-22 | 2014-08-12 | International Business Machines Corporation | Intelligent computer memory management |
| WO2013033461A1 (en) | 2011-08-31 | 2013-03-07 | Rempex Pharmaceuticals, Inc. | Heterocyclic boronic acid ester derivatives and therapeutic uses thereof |
| US9156858B2 (en) | 2012-05-23 | 2015-10-13 | Rempex Pharmaceuticals, Inc. | Boronic acid derivatives and therapeutic uses thereof |
| US10561675B2 (en) | 2012-06-06 | 2020-02-18 | Rempex Pharmaceuticals, Inc. | Cyclic boronic acid ester derivatives and therapeutic uses thereof |
| CN103435650B (zh) * | 2012-12-28 | 2015-12-02 | 南京海融医药科技有限公司 | 单环β-内酰胺类化合物、制备方法及其制药用途 |
| KR20150103269A (ko) | 2013-01-04 | 2015-09-09 | 렘펙스 파머수티클스 인코퍼레이티드 | 보론산 유도체 및 그의 치료적 용도 |
| MX2015008627A (es) | 2013-01-04 | 2015-09-23 | Rempex Pharmaceuticals Inc | Derivados de acido boronico y usos terapeuticos de los mismos. |
| US9101638B2 (en) | 2013-01-04 | 2015-08-11 | Rempex Pharmaceuticals, Inc. | Boronic acid derivatives and therapeutic uses thereof |
| US9241947B2 (en) | 2013-01-04 | 2016-01-26 | Rempex Pharmaceuticals, Inc. | Boronic acid derivatives and therapeutic uses thereof |
| ES2750805T3 (es) | 2014-05-05 | 2020-03-27 | Rempex Pharmaceuticals Inc | Síntesis de sales de boronato y usos de las mismas |
| EP3139930B1 (en) | 2014-05-05 | 2024-08-14 | Melinta Therapeutics, Inc. | Salts and polymorphs of cyclic boronic acid ester derivatives and therapeutic uses thereof |
| AU2015264418A1 (en) | 2014-05-19 | 2016-11-10 | Rempex Pharmaceuticals, Inc. | Boronic acid derivatives and therapeutic uses thereof |
| WO2016003929A1 (en) | 2014-07-01 | 2016-01-07 | Rempex Pharmaceuticals, Inc. | Boronic acid derivatives and therapeutic uses thereof |
| US10662205B2 (en) | 2014-11-18 | 2020-05-26 | Qpex Biopharma, Inc. | Cyclic boronic acid ester derivatives and therapeutic uses thereof |
| EP3233869B1 (en) | 2014-12-19 | 2019-09-25 | Rempex Pharmaceuticals, Inc. | Apparatus and continuous flow process for production of boronic acid derivatives |
| US20180051041A1 (en) | 2015-03-17 | 2018-02-22 | Rempex Pharmaceuticals, Inc. | Boronic acid derivatives and therapeutic uses thereof |
| RU2618433C2 (ru) * | 2015-08-10 | 2017-05-03 | Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Санкт-Петербургский государственный университет" (СПбГУ) | Антимикробная комбинация в отношении устойчивых к карбапенемам грамотрицательных бактерий вида pseudomonas aeruginosa, продуцирующих металло-β-лактамазу |
| MX389349B (es) | 2016-06-30 | 2025-03-20 | Qpex Biopharma Inc | Derivados de ácido borónico y usos terapéuticos de los mismos. |
| CN107641119B (zh) * | 2016-07-21 | 2019-11-08 | 中国科学院上海药物研究所 | 单环β-内酰胺-铁载体轭合物及其制备方法和用途 |
| RU2664434C2 (ru) * | 2016-12-01 | 2018-08-17 | Федеральное государственное бюджетное образовательное учреждение высшего образования "Санкт-Петербургский государственный университет" (СПбГУ) | АНТИМИКРОБНАЯ КОМБИНАЦИЯ В ОТНОШЕНИИ УСТОЙЧИВЫХ К КАРБАПЕНЕМАМ ГРАМОТРИЦАТЕЛЬНЫХ БАКТЕРИЙ ВИДА KLEBSIELLA PNEUMONIAE, ПРОДУЦИРУЮЩИХ МЕТАЛЛО-β-ЛАКТАМАЗУ |
| RU2666619C2 (ru) * | 2016-12-01 | 2018-09-11 | Федеральное государственное бюджетное образовательное учреждение высшего образования "Санкт-Петербургский государственный университет" (СПбГУ) | АНТИМИКРОБНАЯ КОМБИНАЦИЯ В ОТНОШЕНИИ УСТОЙЧИВЫХ К КАРБАПЕНЕМАМ ГРАМОТРИЦАТЕЛЬНЫХ БАКТЕРИЙ ВИДА ACINETOBACTER BAUMANNII, ПРОДУЦИРУЮЩИХ МЕТАЛЛО-β-ЛАКТАМАЗУ |
| US11286270B2 (en) | 2017-10-11 | 2022-03-29 | Qpex Biopharma, Inc. | Boronic acid derivatives and synthesis thereof |
| EP3781576B1 (en) | 2018-04-20 | 2024-06-12 | Qpex Biopharma, Inc. | Boronic acid derivatives and therapeutic uses thereof |
| AU2021266715A1 (en) | 2020-05-05 | 2022-11-17 | Qpex Biopharma, Inc. | Boronic acid derivatives and synthesis, polymorphic forms, and therapeutic uses thereof |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4775670A (en) * | 1980-09-29 | 1988-10-04 | E. R. Squibb & Sons, Inc. | 2-oxo-1-azetidinesulfonic acid salts |
| US4632985A (en) * | 1985-06-03 | 1986-12-30 | E. R. Squibb & Sons, Inc. | 3-acylamino-2-oxo-1-azetidinesulfonic acids |
| US5006650A (en) * | 1987-02-11 | 1991-04-09 | The Upjohn Company | Novel N-1 substituted beta-lactams as antibiotics |
| JPH02502455A (ja) * | 1987-02-27 | 1990-08-09 | ジ・アップジョン・カンパニー | ピリドンカルボン酸または酸誘導体を含有する抗生物質β‐ラクタム |
| US5112968A (en) * | 1989-07-28 | 1992-05-12 | E. R. Squibb & Sons, Inc. | Monobactam hydrazide derivatives |
| CA2024282A1 (en) * | 1989-09-21 | 1991-03-22 | Peter H. Ermann | Heterocyclic hydrazide derivatives of monocyclic beta-lactam antibiotics |
| ZA918014B (en) * | 1990-11-05 | 1992-07-29 | Squibb & Sons Inc | Heteroaroyl derivatives of monocyclic beta-lactam antibiotics |
-
1997
- 1997-04-24 US US08/840,608 patent/US5888998A/en not_active Expired - Fee Related
-
1998
- 1998-04-23 JP JP54535898A patent/JP2001521549A/ja not_active Ceased
- 1998-04-23 KR KR1019997009755A patent/KR20010020181A/ko not_active Withdrawn
- 1998-04-23 CA CA002287219A patent/CA2287219C/en not_active Expired - Fee Related
- 1998-04-23 DE DE69808901T patent/DE69808901T2/de not_active Expired - Fee Related
- 1998-04-23 WO PCT/IB1998/000622 patent/WO1998047895A1/en not_active Ceased
- 1998-04-23 AU AU69314/98A patent/AU740446B2/en not_active Ceased
- 1998-04-23 EP EP98915027A patent/EP0979229B1/en not_active Expired - Lifetime
- 1998-04-23 HU HU0001269A patent/HUP0001269A3/hu unknown
-
1999
- 1999-10-20 NO NO995108A patent/NO995108L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| NO995108D0 (no) | 1999-10-20 |
| US5888998A (en) | 1999-03-30 |
| EP0979229B1 (en) | 2002-10-23 |
| AU6931498A (en) | 1998-11-13 |
| AU740446B2 (en) | 2001-11-01 |
| DE69808901D1 (de) | 2002-11-28 |
| KR20010020181A (ko) | 2001-03-15 |
| HUP0001269A3 (en) | 2001-11-28 |
| CA2287219C (en) | 2010-01-12 |
| CA2287219A1 (en) | 1998-10-29 |
| WO1998047895A1 (en) | 1998-10-29 |
| EP0979229A1 (en) | 2000-02-16 |
| DE69808901T2 (de) | 2003-07-31 |
| JP2001521549A (ja) | 2001-11-06 |
| HUP0001269A2 (hu) | 2001-05-28 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| NO995108L (no) | 2-okso-1-azetidinsulfonsyrederivater som potente <beta>-laktamase inhibitorer | |
| NO20064669L (no) | Dipeptidylpeptidaseinhibitorer | |
| CA2266107A1 (en) | Aralkyl and aralkylidene heterocyclic lactams and imides | |
| IE781140L (en) | Penicillanic acid s-oxides | |
| WO2003057688A3 (en) | Oxo or oxy-pyridine compounds as 5-ht4 receptor modulators | |
| HUP0203122A2 (hu) | Fab I inhibitorok, eljárás az előállításukra, ezeket tartalmazó gyógyszerkészítmények és alkalmazásuk | |
| AP1902A (en) | N-aryl-2-oxazolidinone-5-carboxamides and their derivatives and their use as antibacterials | |
| BG103655A (bg) | Дизаместени бициклични хетероциклени съединения, тяхното получаване и приложението им като лекарствени средства | |
| BR0116571A (pt) | Compostos heterocìclicos tendo atividade antibacteriana, processo para sua preparação e composições farmacêuticas contendo os mesmos | |
| NO781322L (no) | Cephemderivater og fremgangsmaate til deres fremstilling | |
| AR064130A1 (es) | Derivados de tiazoles y piridinas como antibacterianos. composiciones farmaceuticas. | |
| NO20015669D0 (no) | Heterocykliske substituerte aminoazacykler nyttige som sentralnervesystemmidler | |
| HK98486A (en) | Quinoline carboxylic acid derivatives and their preparation | |
| DK1078923T3 (da) | Fremgangsmåde til fremstilling af benzothiophenderivater | |
| NO20074763L (no) | (1,5-difenyl-1H-pyrazol-3-yl)oksadiazolderivater, fremgangsmate ved fremstilling derav og anvendelse av samme i terapi | |
| NO952493L (no) | Pyrrolidin- og tiazolidinderivater, deres fremstilling samt medikamenter inneholdende forbindelsene | |
| NO20072753L (no) | 3-Etylidenhydrazinosubstituerte heterocykliske forbindelser som trombopoietinreseptoraktivatorer | |
| NO20063132L (no) | Naftyridinderivater og deres anvendelse som modulatorer av muskarinreceptorer | |
| NO934836L (no) | Fremgangsmåte for fremstilling og anvendelse som medikament eller diagnostikum av 2,4-substituerte 5-(N-substituerte-sulfamoyl)-benzoylguanidiner, og medikamenter som inneholder disse | |
| CA1135687A (en) | .beta.-LACTAM ANTIBIOTICS, THEIR PRODUCTION, AND THEIR MEDICINAL USE | |
| EP1186604A4 (en) | Benzazepine derivatives, process for the preparation of the same and uses thereof | |
| AU5349286A (en) | 5-(azolyloxyphenylcarbamoyl)barbituric acid derivatives as anthelmintics | |
| NL2022854B1 (en) | Prodrug inhibitors | |
| ATE82976T1 (de) | Cephalosporinderivate. | |
| EP1336611A4 (en) | DESHALOGENVERBINDUNGEN |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |