NO992228L - 1-(3-aminoindazol-5-yl)-3-fenylmetyl-syklisk urea egnet som HIV protease inhibitor - Google Patents
1-(3-aminoindazol-5-yl)-3-fenylmetyl-syklisk urea egnet som HIV protease inhibitorInfo
- Publication number
- NO992228L NO992228L NO992228A NO992228A NO992228L NO 992228 L NO992228 L NO 992228L NO 992228 A NO992228 A NO 992228A NO 992228 A NO992228 A NO 992228A NO 992228 L NO992228 L NO 992228L
- Authority
- NO
- Norway
- Prior art keywords
- hiv protease
- phenylmethylcyclic
- aminoindazol
- protease inhibitor
- urea suitable
- Prior art date
Links
- -1 3-Aminoindazol-5-yl Chemical group 0.000 title 1
- 229940122440 HIV protease inhibitor Drugs 0.000 title 1
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 title 1
- 239000004202 carbamide Substances 0.000 title 1
- 239000004030 hiv protease inhibitor Substances 0.000 title 1
- 238000009007 Diagnostic Kit Methods 0.000 abstract 1
- 108010010369 HIV Protease Proteins 0.000 abstract 1
- 208000036142 Viral infection Diseases 0.000 abstract 1
- 238000004458 analytical method Methods 0.000 abstract 1
- 239000003153 chemical reaction reagent Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000003112 inhibitor Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 239000000651 prodrug Substances 0.000 abstract 1
- 229940002612 prodrug Drugs 0.000 abstract 1
- 150000003839 salts Chemical group 0.000 abstract 1
- 230000009385 viral infection Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Virology (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Communicable Diseases (AREA)
- AIDS & HIV (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Molecular Biology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US2974596P | 1996-11-08 | 1996-11-08 | |
US74710496A | 1996-11-08 | 1996-11-08 | |
PCT/US1997/020035 WO1998020008A1 (en) | 1996-11-08 | 1997-11-04 | 1-(3-aminoindazol-5-yl)-3-phenylmethyl-cyclic ureas useful as hiv protease inhibitors |
Publications (2)
Publication Number | Publication Date |
---|---|
NO992228D0 NO992228D0 (no) | 1999-05-07 |
NO992228L true NO992228L (no) | 1999-06-07 |
Family
ID=26705293
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO992228A NO992228L (no) | 1996-11-08 | 1999-05-07 | 1-(3-aminoindazol-5-yl)-3-fenylmetyl-syklisk urea egnet som HIV protease inhibitor |
Country Status (21)
Country | Link |
---|---|
EP (1) | EP0937067B1 (sk) |
JP (1) | JP2001503428A (sk) |
KR (1) | KR20000053122A (sk) |
CN (1) | CN1235602A (sk) |
AT (1) | ATE244714T1 (sk) |
AU (1) | AU5165198A (sk) |
BR (1) | BR9712910A (sk) |
CA (1) | CA2270966A1 (sk) |
CZ (1) | CZ157599A3 (sk) |
DE (1) | DE69723456T2 (sk) |
EA (1) | EA199900452A1 (sk) |
EE (1) | EE9900188A (sk) |
ES (1) | ES2202645T3 (sk) |
HU (1) | HUP9904676A2 (sk) |
IL (1) | IL129727A0 (sk) |
LV (1) | LV12375B (sk) |
NO (1) | NO992228L (sk) |
PL (1) | PL333421A1 (sk) |
SI (1) | SI20074A (sk) |
SK (1) | SK59699A3 (sk) |
WO (1) | WO1998020008A1 (sk) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1998043969A1 (en) * | 1997-03-31 | 1998-10-08 | Dupont Pharmaceuticals Company | Indazoles of cyclic ureas useful as hiv protease inhibitors |
US7135575B2 (en) | 2003-03-03 | 2006-11-14 | Array Biopharma, Inc. | P38 inhibitors and methods of use thereof |
DK1981851T3 (da) | 2006-01-31 | 2012-03-19 | Array Biopharma Inc | Kinaseinhibitorer og fremgangsmåder til anvendelse deraf |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5610294A (en) * | 1991-10-11 | 1997-03-11 | The Du Pont Merck Pharmaceutical Company | Substituted cyclic carbonyls and derivatives thereof useful as retroviral protease inhibitors |
US5532357A (en) * | 1995-06-07 | 1996-07-02 | The Dupont Merck Pharmaceutical Company | Method for preparing N-monosubstituted and N,N'-disubstituted unsymmetrical cyclic ureas |
-
1997
- 1997-11-04 CZ CZ991575A patent/CZ157599A3/cs unknown
- 1997-11-04 EP EP97946494A patent/EP0937067B1/en not_active Expired - Lifetime
- 1997-11-04 IL IL12972797A patent/IL129727A0/xx unknown
- 1997-11-04 WO PCT/US1997/020035 patent/WO1998020008A1/en not_active Application Discontinuation
- 1997-11-04 CN CN97199419A patent/CN1235602A/zh active Pending
- 1997-11-04 DE DE69723456T patent/DE69723456T2/de not_active Expired - Fee Related
- 1997-11-04 JP JP52168198A patent/JP2001503428A/ja active Pending
- 1997-11-04 ES ES97946494T patent/ES2202645T3/es not_active Expired - Lifetime
- 1997-11-04 HU HU9904676A patent/HUP9904676A2/hu unknown
- 1997-11-04 SK SK596-99A patent/SK59699A3/sk unknown
- 1997-11-04 CA CA002270966A patent/CA2270966A1/en not_active Abandoned
- 1997-11-04 AT AT97946494T patent/ATE244714T1/de not_active IP Right Cessation
- 1997-11-04 EE EEP199900188A patent/EE9900188A/xx unknown
- 1997-11-04 AU AU51651/98A patent/AU5165198A/en not_active Abandoned
- 1997-11-04 SI SI9720072A patent/SI20074A/sl unknown
- 1997-11-04 KR KR1019990704048A patent/KR20000053122A/ko not_active Application Discontinuation
- 1997-11-04 BR BR9712910A patent/BR9712910A/pt not_active Application Discontinuation
- 1997-11-04 PL PL97333421A patent/PL333421A1/xx unknown
- 1997-11-04 EA EA199900452A patent/EA199900452A1/ru unknown
-
1999
- 1999-04-29 LV LVP-99-76A patent/LV12375B/en unknown
- 1999-05-07 NO NO992228A patent/NO992228L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
DE69723456D1 (de) | 2003-08-14 |
JP2001503428A (ja) | 2001-03-13 |
IL129727A0 (en) | 2000-02-29 |
PL333421A1 (en) | 1999-12-06 |
LV12375B (en) | 2000-04-20 |
CZ157599A3 (cs) | 1999-11-17 |
BR9712910A (pt) | 2000-03-21 |
ES2202645T3 (es) | 2004-04-01 |
EP0937067A1 (en) | 1999-08-25 |
DE69723456T2 (de) | 2004-05-27 |
HUP9904676A2 (hu) | 2000-06-28 |
LV12375A (lv) | 1999-11-20 |
SI20074A (sl) | 2000-04-30 |
NO992228D0 (no) | 1999-05-07 |
SK59699A3 (en) | 1999-12-10 |
CN1235602A (zh) | 1999-11-17 |
EE9900188A (et) | 1999-12-15 |
AU5165198A (en) | 1998-05-29 |
ATE244714T1 (de) | 2003-07-15 |
WO1998020008A1 (en) | 1998-05-14 |
EA199900452A1 (ru) | 2000-02-28 |
CA2270966A1 (en) | 1998-05-14 |
KR20000053122A (ko) | 2000-08-25 |
EP0937067B1 (en) | 2003-07-09 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
NO932620L (no) | Amindiol-proteaseinhibitorer | |
EA199900907A1 (ru) | 4,4-дизамещенные 3,4-дигидро-2(1н)-хиназолиноны, полезные в качестве ингибиторов обратной транскриптазы вич | |
BG100455A (en) | Hiv protease inhibitors | |
DK0816376T3 (da) | Thrombininhibitorer som antikoagulante midler | |
ES2184763T3 (es) | Inhibidores de trombina. | |
NO20022095L (no) | Heterocyklisk substituerte pyrazoloner | |
DK0741694T3 (da) | Phenyleddikesyrederivater, fremgangsmåder og mellemprodukter til deres fremstilling og midler indeholdende disse | |
DK0528858T3 (da) | Inhibitorer af dipeptidyl-aminopeptidase type IV | |
BR9908280A (pt) | Inibidores de enzimas de fosfolipase | |
PT750618E (pt) | Derivados de oxazolidinona e composicoes farmaceuticas que os contem | |
DK0656887T3 (da) | Hydroxyethylaminosulfonamider til anvendelse som inhibitorer af retrovirale proteaser | |
WO1995033464A3 (en) | Retroviral protease inhibitor combinations | |
BR9810177A (pt) | Composto, formulação farmacêutica, uso de um composto, e, processos para tratamento de uma condição onde a inibição da trombina é requerida e para a preparação de compostos | |
SE9602263D0 (sv) | New amino acid derivatives | |
EE200300168A (et) | Tripeptidüülpeptidaasi inhibiitorid, nende valmistamine ja kasutamine ravimina ning neid sisaldav farmatseutiline kompositsioon | |
DK0763017T3 (da) | N-(3-amino-2-hydroxybutyl)sulfonamidderivater som HIV-proteaseinhibitorer | |
ES2171945T3 (es) | Derivados aromaticos de amidina que sirven de inhibidores selectivos de la trombina. | |
BR0007453A (pt) | Composto, formulação farmacêutica, uso de umcomposto, método de tratamento de uma condiçãoonde a inibição da trombina é requerida e,processo de preparação de um composto | |
YU62504A (sh) | Triciklična 2-pirimidonska jedinjenja korisna kao inhibitori hiv reverzne transkriptoze | |
NO992228L (no) | 1-(3-aminoindazol-5-yl)-3-fenylmetyl-syklisk urea egnet som HIV protease inhibitor | |
PT975588E (pt) | Compostos antipicornavirais, composicoes que os contem e metodos para a sua utilizacao | |
NO20044466L (no) | Plasma-karboksypeptidase B-inhibitorer | |
DK0604186T3 (da) | HIV-proteaseinhibitorer, som er egnede til behandling af AIDS | |
WO2004002410A3 (en) | 2,4-disubstituted-pyridine n-oxides useful as hiv reverse transcriptase inhibitors | |
LT2003003A (en) | Tricyclic 2-pyridone compounds useful as hiv reverse transcriptase inhibitors |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FC2A | Withdrawal, rejection or dismissal of laid open patent application |