NO985160L - Anvendelse av interleukin-10 til fremstilling av en populasjon av suppresso - Google Patents

Anvendelse av interleukin-10 til fremstilling av en populasjon av suppresso

Info

Publication number
NO985160L
NO985160L NO985160A NO985160A NO985160L NO 985160 L NO985160 L NO 985160L NO 985160 A NO985160 A NO 985160A NO 985160 A NO985160 A NO 985160A NO 985160 L NO985160 L NO 985160L
Authority
NO
Norway
Prior art keywords
interleukin
population
suppresso
prepare
alloantigens
Prior art date
Application number
NO985160A
Other languages
English (en)
Other versions
NO985160D0 (no
Inventor
Maria-Grazia Roncarolo
Malefyt Rene De Waal
Rosa Bacchetta
Herve M Groux
Jan E De Vries
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Publication of NO985160D0 publication Critical patent/NO985160D0/no
Publication of NO985160L publication Critical patent/NO985160L/no

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/20—Interleukins [IL]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/001—Preparations to induce tolerance to non-self, e.g. prior to transplantation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/20—Interleukins [IL]
    • A61K38/2066—IL-10
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0008—Antigens related to auto-immune diseases; Preparations to induce self-tolerance
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0636—T lymphocytes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K2035/122—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells for inducing tolerance or supression of immune responses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/515—Animal cells
    • A61K2039/5158—Antigen-pulsed cells, e.g. T-cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/20—Cytokines; Chemokines
    • C12N2501/23—Interleukins [IL]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/50—Cell markers; Cell surface determinants
    • C12N2501/515—CD3, T-cell receptor complex

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Mycology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Transplantation (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Hematology (AREA)
  • Rheumatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Interleukin-10 for fremstil- ling av en populasjon av celler som er i stand til å inhibere eller under- trykke reaksjoner på alloantigener, f.eks. ved graft-versus-host-sykdom eller vevsavstøtning. Interleukin-10 for reduksjon av responser ved blandet lymfocyttrespons (MLR) er også be- skrevet. Eksogent eller indusert, endo- gent IL-10 kan anvendes for inhibering eller undertrykkelse av reaksjonene på alloantigener.
NO985160A 1996-05-06 1998-11-05 Anvendelse av interleukin-10 til fremstilling av en populasjon av suppresso NO985160L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/643,810 US6277635B1 (en) 1992-03-04 1996-05-06 Use of interleukin-10 to produce a population of suppressor cells
PCT/US1997/007120 WO1997042324A1 (en) 1996-05-06 1997-05-02 Use of interleukin-10 to produce a population of suppressor cells

Publications (2)

Publication Number Publication Date
NO985160D0 NO985160D0 (no) 1998-11-05
NO985160L true NO985160L (no) 1999-01-06

Family

ID=24582315

Family Applications (1)

Application Number Title Priority Date Filing Date
NO985160A NO985160L (no) 1996-05-06 1998-11-05 Anvendelse av interleukin-10 til fremstilling av en populasjon av suppresso

Country Status (16)

Country Link
US (1) US6277635B1 (no)
EP (1) EP0906428A1 (no)
JP (1) JP2000509604A (no)
KR (1) KR20000010799A (no)
AR (1) AR006942A1 (no)
AU (1) AU2927597A (no)
BR (1) BR9709307A (no)
CA (1) CA2253803A1 (no)
CZ (1) CZ347798A3 (no)
IL (1) IL126658A0 (no)
NO (1) NO985160L (no)
NZ (1) NZ332413A (no)
PL (1) PL329732A1 (no)
SK (1) SK151898A3 (no)
WO (1) WO1997042324A1 (no)
ZA (1) ZA973815B (no)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6358506B1 (en) 1997-11-05 2002-03-19 University Of Southern California Use of cytokines and mitogens to inhibit pathological immune responses
AU1864999A (en) * 1997-12-15 1999-07-05 Universite Laval Methods and compositions for improving the success of cell transplantation in a host
EP1061949B1 (en) 1998-03-03 2009-07-15 University of Southern California Cytokines and mitogens to inhibit graft-versus-host disease
US6803036B1 (en) 1998-03-03 2004-10-12 University Of Southern California Use of cytokines, cells and mitogens to inhibit graft versus host disease
ATE431399T1 (de) * 1999-09-01 2009-05-15 Univ Southern California Verwendung von cytokinen, zellen und mitogene zur hemmung der graft-versus-host krankheit
GB9928193D0 (en) * 1999-11-29 2000-01-26 Univ Bristol Cell treatment method
CA2405806A1 (en) * 2000-04-11 2001-10-18 University Of Southern California A method to prevent graft rejection using tgf-.beta. to induce t suppressor cells
EP2295450B1 (en) 2000-09-29 2015-01-28 Merck Sharp & Dohme Corp. Pegylated interleukin-10
FR2824567B1 (fr) * 2001-05-11 2003-08-08 Inst Nat Sante Rech Med Procede d'obtention de lymphocytes tr1 regulateurs specifiques d'antigene
AU2003219611A1 (en) * 2002-03-07 2003-09-16 Academisch Ziekenhuis Bij De Universiteit Van Amsterdam Il-10 gene transfer to peripheral blood mononuclear cells
GB0214528D0 (en) * 2002-06-24 2002-08-07 Univ Aberdeen Materials and methods for induction of immune tolerance
US20060127357A1 (en) 2002-11-29 2006-06-15 Roncarolo Maria G Rapamycin and il-10 for the treatment of immune diseases
FR2852967B1 (fr) * 2003-03-26 2007-12-07 Txcell Procede d'obtention de cellules dendritiques et de cellules t
FR2856700B1 (fr) * 2003-06-24 2007-06-08 Txcell Procede d'identification de lymphocytes tr1 regulateurs par la presence et la surexpression de molecules specifiques et ses applications
EP2591786B1 (en) 2003-10-16 2017-04-12 Cancure Limited Immunomodulating compositions and uses therefor
CA2545841A1 (en) * 2003-11-12 2005-05-26 Txcell Use of lipopeptides for activating t lymphocytes through the skin
JP4863452B2 (ja) * 2006-03-30 2012-01-25 国立大学法人 千葉大学 ヒトＴｈ１／Ｔｈ２分化誘導系及びその用途
CA2652148C (en) 2006-05-12 2016-10-04 Fondazione Centro San Raffaele Del Monte Tabor Tolerogenic dendritic cells, method for their production and uses thereof
US20120058096A1 (en) 2009-03-03 2012-03-08 St. Jude Children's Research Hospital Compositions and methods for generating interleukin-35-induced regulatory t cells
US10143778B2 (en) * 2010-12-21 2018-12-04 Cormatrix Cardiovascular, Inc Cardiovascular prostheses
CA2877286C (en) 2012-06-18 2023-05-16 Yale University Compositions and methods for diminishing an immune response
CA2782942C (en) * 2012-07-12 2019-08-27 Canadian Blood Services Method for inducing immune tolerance using polymer-modified antigenic leukocytes
DK3019176T3 (da) 2013-07-12 2020-06-22 Canadian Blood Services Anvendelse af acellulære pro-inflammatoriske sammensætninger og fremgangsmåde til fremstilling heraf
KR101868950B1 (ko) 2017-05-18 2018-06-19 연세대학교 산학협력단 Ｉｌ－１０을 발현하는 신경줄기세포를 포함하는 중추 신경계 질환 또는 손상의 치료용 약학적 조성물 및 이를 이용한 방법

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4483920A (en) 1982-05-17 1984-11-20 Hahnemann University Immobilization of message RNA directly from cells onto filter material
US4559310A (en) 1983-05-20 1985-12-17 Dana Farber Cancer Institute Assay methods and systems utilizing mast cell clones
IL94878A (en) 1989-06-28 2003-01-12 Schering Corp Cytokine synthesis inhibitory factor, antagonists thereof and methods of using same

Also Published As

Publication number Publication date
JP2000509604A (ja) 2000-08-02
SK151898A3 (en) 2000-04-10
BR9709307A (pt) 1999-08-10
IL126658A0 (en) 1999-08-17
NZ332413A (en) 2000-10-27
WO1997042324A1 (en) 1997-11-13
US6277635B1 (en) 2001-08-21
AR006942A1 (es) 1999-09-29
AU2927597A (en) 1997-11-26
ZA973815B (en) 1997-11-03
EP0906428A1 (en) 1999-04-07
PL329732A1 (en) 1999-04-12
KR20000010799A (ko) 2000-02-25
CZ347798A3 (cs) 1999-03-17
CA2253803A1 (en) 1997-11-13
NO985160D0 (no) 1998-11-05

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