NO984344D0 - Ny asymmetriske syntese av R-<alfa>-propylpiperonyalamin og dets analoger - Google Patents

Ny asymmetriske syntese av R-<alfa>-propylpiperonyalamin og dets analoger

Info

Publication number
NO984344D0
NO984344D0 NO984344A NO984344A NO984344D0 NO 984344 D0 NO984344 D0 NO 984344D0 NO 984344 A NO984344 A NO 984344A NO 984344 A NO984344 A NO 984344A NO 984344 D0 NO984344 D0 NO 984344D0
Authority
NO
Norway
Prior art keywords
propylpiperonyalamine
alfa
analogs
asymmetric synthesis
new asymmetric
Prior art date
Application number
NO984344A
Other languages
English (en)
Norwegian (no)
Other versions
NO984344L (no
Inventor
Hui-Yin Li
Luigi Anzalone
Robert Eugebe Waltermire
Original Assignee
Du Pont Merck Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Du Pont Merck Pharma filed Critical Du Pont Merck Pharma
Publication of NO984344L publication Critical patent/NO984344L/no
Publication of NO984344D0 publication Critical patent/NO984344D0/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D317/00Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D317/48Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
    • C07D317/50Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to atoms of the carbocyclic ring
    • C07D317/58Radicals substituted by nitrogen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
NO984344A 1996-03-22 1998-09-18 Ny asymmetriske syntese av R-<alfa>-propylpiperonyalamin og dets analoger NO984344D0 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US1395596P 1996-03-22 1996-03-22
PCT/US1997/003466 WO1997034887A1 (en) 1996-03-22 1997-03-17 NOVEL ASYMMETRIC SYNTHESIS OF R-α-PROPYL-PIPERONYL AMINE AND ITS ANALOGS

Publications (2)

Publication Number Publication Date
NO984344L NO984344L (no) 1998-09-18
NO984344D0 true NO984344D0 (no) 1998-09-18

Family

ID=21762727

Family Applications (1)

Application Number Title Priority Date Filing Date
NO984344A NO984344D0 (no) 1996-03-22 1998-09-18 Ny asymmetriske syntese av R-<alfa>-propylpiperonyalamin og dets analoger

Country Status (23)

Country Link
US (1) US5932749A (et)
EP (1) EP0888329A1 (et)
JP (1) JP2000506891A (et)
KR (1) KR20000064735A (et)
CN (1) CN1218463A (et)
AR (1) AR006521A1 (et)
AU (1) AU719633B2 (et)
BR (1) BR9708233A (et)
CA (1) CA2249401A1 (et)
CZ (1) CZ295098A3 (et)
EA (1) EA001207B1 (et)
EE (1) EE9800299A (et)
HR (1) HRP970165A2 (et)
IL (1) IL126223A0 (et)
LT (1) LT4540B (et)
LV (1) LV12259B (et)
NO (1) NO984344D0 (et)
NZ (1) NZ331875A (et)
PL (1) PL329070A1 (et)
SI (1) SI9720023A (et)
SK (1) SK127398A3 (et)
WO (1) WO1997034887A1 (et)
ZA (1) ZA972342B (et)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000012474A1 (en) 1998-08-31 2000-03-09 Du Pont Pharmaceuticals Company An efficient process for the preparation of a human leukocyte elastase inhibitor
CN101353324A (zh) * 2001-09-12 2009-01-28 阿诺麦德股份有限公司 对映体纯的氨基取代稠合双环的合成
WO2010077798A2 (en) * 2008-12-15 2010-07-08 Taigen Biotechnology Co., Ltd. Stereoselective synthesis of piperidine derivatives
US9126906B2 (en) 2012-02-21 2015-09-08 Celgene Corporation Asymmetric synthetic processes for the preparation of aminosulfone compounds
AR090100A1 (es) 2012-02-21 2014-10-22 Celgene Corp Procesos para la preparacion de la (s)-1-(3-etoxi-4-metoxifenil)-2-metanosulfoniletilamina
WO2017106332A1 (en) 2015-12-14 2017-06-22 X4 Pharmaceuticals, Inc. Methods for treating cancer
CN109069426B (zh) 2015-12-14 2021-10-29 X4 制药有限公司 治疗癌症的方法
PL3393468T3 (pl) 2015-12-22 2023-01-23 X4 Pharmaceuticals, Inc. Metody leczenia niedoboru odporności
WO2017177230A1 (en) 2016-04-08 2017-10-12 X4 Pharmaceuticals, Inc. Methods for treating cancer
CN109641838A (zh) 2016-06-21 2019-04-16 X4 制药有限公司 Cxcr4抑制剂及其用途
CN116554168A (zh) 2016-06-21 2023-08-08 X4 制药有限公司 Cxcr4抑制剂及其用途
CA3027495A1 (en) 2016-06-21 2017-12-28 X4 Pharmaceuticals, Inc. Cxcr4 inhibitors and uses thereof
US10548889B1 (en) 2018-08-31 2020-02-04 X4 Pharmaceuticals, Inc. Compositions of CXCR4 inhibitors and methods of preparation and use
CA3230380A1 (en) 2021-09-01 2023-03-09 Nicholas MORRA Synthesis of mdma or its optically active (r)- or (s)-mdma isomers
WO2023044027A1 (en) * 2021-09-17 2023-03-23 ATAI Life Sciences AG Preparation of optically active enantiomers of piperonyl amines by resolution of the diastereomeric salts
WO2023056102A1 (en) 2021-10-01 2023-04-06 ATAI Life Sciences AG Novel prodrugs of mdma, mda, and derivatives thereof
US11912680B2 (en) 2021-12-28 2024-02-27 Empathbio, Inc. Nitric oxide releasing prodrugs of MDA and MDMA

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3819438A1 (de) * 1987-06-30 1989-01-19 Basf Ag Verfahren zur herstellung von optisch aktiven 1-arylethylaminen
IL99658A0 (en) * 1990-10-15 1992-08-18 Merck & Co Inc Substituted azetidinones and pharmaceutical compositions containing them
US5149838A (en) * 1991-09-20 1992-09-22 Merck & Co., Inc. Intermediates for substituted azetidinones useful as anti-inflammatory and antidegenerative agents

Also Published As

Publication number Publication date
EP0888329A1 (en) 1999-01-07
EA001207B1 (ru) 2000-12-25
KR20000064735A (ko) 2000-11-06
SI9720023A (sl) 1999-04-30
CZ295098A3 (cs) 1999-03-17
NO984344L (no) 1998-09-18
EA199800844A1 (ru) 1999-02-25
IL126223A0 (en) 1999-05-09
HRP970165A2 (en) 1998-04-30
NZ331875A (en) 2000-01-28
LT98132A (en) 1999-03-25
PL329070A1 (en) 1999-03-15
AR006521A1 (es) 1999-09-08
LV12259B (en) 1999-09-20
CN1218463A (zh) 1999-06-02
EE9800299A (et) 1999-06-15
AU719633B2 (en) 2000-05-11
CA2249401A1 (en) 1997-09-25
LV12259A (lv) 1999-04-20
US5932749A (en) 1999-08-03
SK127398A3 (en) 1999-04-13
LT4540B (lt) 1999-08-25
ZA972342B (en) 1998-09-18
AU2196897A (en) 1997-10-10
JP2000506891A (ja) 2000-06-06
WO1997034887A1 (en) 1997-09-25
BR9708233A (pt) 2000-01-04

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