NO983802D0 - Benzothiofener, formuleringer inneholdende samme og fremgangsmÕter - Google Patents

Benzothiofener, formuleringer inneholdende samme og fremgangsmÕter

Info

Publication number
NO983802D0
NO983802D0 NO983802A NO983802A NO983802D0 NO 983802 D0 NO983802 D0 NO 983802D0 NO 983802 A NO983802 A NO 983802A NO 983802 A NO983802 A NO 983802A NO 983802 D0 NO983802 D0 NO 983802D0
Authority
NO
Norway
Prior art keywords
benzothiophenes
methods
same
formulations containing
formulations
Prior art date
Application number
NO983802A
Other languages
English (en)
Norwegian (no)
Other versions
NO983802L (no
Inventor
George Joseph Cullinan
Alan D Palkowitz
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9604912.7A external-priority patent/GB9604912D0/en
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of NO983802L publication Critical patent/NO983802L/no
Publication of NO983802D0 publication Critical patent/NO983802D0/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/62Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • C07D333/64Oxygen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/24Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/30Oestrogens
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/54Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C07D333/56Radicals substituted by oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Endocrinology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Epidemiology (AREA)
  • Reproductive Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Plural Heterocyclic Compounds (AREA)
NO983802A 1996-02-22 1998-08-19 Benzothiofener, formuleringer inneholdende samme og fremgangsmÕter NO983802D0 (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US1204496P 1996-02-22 1996-02-22
GBGB9604912.7A GB9604912D0 (en) 1996-03-08 1996-03-08 Benzothiophenes, formulations containing same, and methods
PCT/US1997/002464 WO1997030709A1 (en) 1996-02-22 1997-02-19 Benzothiophenes, formulations containing same, and methods

Publications (2)

Publication Number Publication Date
NO983802L NO983802L (no) 1998-08-19
NO983802D0 true NO983802D0 (no) 1998-08-19

Family

ID=26308887

Family Applications (1)

Application Number Title Priority Date Filing Date
NO983802A NO983802D0 (no) 1996-02-22 1998-08-19 Benzothiofener, formuleringer inneholdende samme og fremgangsmÕter

Country Status (23)

Country Link
EP (1) EP0791591B1 (ru)
JP (1) JP2000505455A (ru)
KR (1) KR19990087091A (ru)
CN (1) CN1211921A (ru)
AR (2) AR005970A1 (ru)
AT (1) ATE204869T1 (ru)
AU (1) AU713204B2 (ru)
BR (1) BR9707657A (ru)
CA (1) CA2246721A1 (ru)
CO (1) CO4761064A1 (ru)
CZ (1) CZ260798A3 (ru)
DE (1) DE69706338T2 (ru)
DK (1) DK0791591T3 (ru)
EA (1) EA000767B1 (ru)
ES (1) ES2162196T3 (ru)
IL (1) IL125863A (ru)
NO (1) NO983802D0 (ru)
NZ (1) NZ331461A (ru)
PL (1) PL328832A1 (ru)
PT (1) PT791591E (ru)
TR (1) TR199801612T2 (ru)
WO (1) WO1997030709A1 (ru)
YU (1) YU6797A (ru)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999015521A1 (en) * 1997-09-23 1999-04-01 Eli Lilly And Company Benzothiophenes
US6465445B1 (en) 1998-06-11 2002-10-15 Endorecherche, Inc. Medical uses of a selective estrogen receptor modulator in combination with sex steroid precursors
US7005428B1 (en) 1998-06-11 2006-02-28 Endorecherche, Inc. Medical uses of a selective estrogen receptor modulator in combination with sex steroid precursors
US6060488A (en) * 1998-09-22 2000-05-09 Eli Lilly And Company Benzothiophenes for treating estrogen deficiency
ES2225641T3 (es) * 2000-12-05 2005-03-16 F. Hoffmann-La Roche Ag Derivados de benzofurano y benzotiofeno como inhibidores de cox-2 selectivos.
MXPA05000898A (es) * 2002-07-22 2005-05-16 Lilly Co Eli Moduladores de receptor de estrogeno selectivos que contiene, un grupo fenilsulfonilo.
EP1782810A3 (en) * 2002-07-22 2007-05-23 Eli Lilly & Company Selective estrogen receptor modulators containing a phenylsulfonyl group
CA2499819A1 (en) 2002-09-30 2004-04-08 A/S Gea Farmaceutisk Fabrik Novel raloxifene acid addition salts and/or solvates thereof, improved method for purification of said raloxifene acid addition salts and/or solvates thereof and pharmaceutical compositions comprising these
NZ541126A (en) * 2003-02-25 2008-07-31 Lilly Co Eli Crystalline non-solvated 1-(4-(2-piperidinylethoxy)phenoxy)-2-(4-methanesulfonylphenyl)-6-hydroxynaphthalene hydrochloride
US20080227814A1 (en) * 2004-01-29 2008-09-18 Jeffrey Alan Dodge Selective Estrogen Receptor Modulators
GR1005694B (el) * 2005-06-08 2007-10-22 Αλεξης Μιχαηλ Ιστοειδικα αντιοιστρογονα ειδικα για τον αλφα υποδοχεα των οιστρογονων
CN111018770A (zh) * 2019-12-26 2020-04-17 北京鑫开元医药科技有限公司 一种巴多昔芬氧化物的制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PH18628A (en) * 1981-04-03 1985-08-23 Lilly Co Eli "6-hydroxy-2-(4-hydroxyphenyl)-3 4-(2- piperidine or 3-methylpyrollidine -benzo b thiophene compounds
US5482949A (en) * 1993-03-19 1996-01-09 Eli Lilly And Company Sulfonate derivatives of 3-aroylbenzo[b]thiophenes
US6756388B1 (en) * 1993-10-12 2004-06-29 Pfizer Inc. Benzothiophenes and related compounds as estrogen agonists
US5510357A (en) * 1995-02-28 1996-04-23 Eli Lilly And Company Benzothiophene compounds as anti-estrogenic agents

Also Published As

Publication number Publication date
IL125863A0 (en) 1999-04-11
BR9707657A (pt) 1999-07-27
EA000767B1 (ru) 2000-04-24
WO1997030709A1 (en) 1997-08-28
DE69706338T2 (de) 2002-06-13
PT791591E (pt) 2001-12-28
PL328832A1 (en) 1999-02-15
IL125863A (en) 2000-10-31
TR199801612T2 (xx) 1998-11-23
DE69706338D1 (de) 2001-10-04
EP0791591A1 (en) 1997-08-27
AR005970A1 (es) 1999-07-21
AU713204B2 (en) 1999-11-25
JP2000505455A (ja) 2000-05-09
AU2276497A (en) 1997-09-10
CN1211921A (zh) 1999-03-24
ATE204869T1 (de) 2001-09-15
NO983802L (no) 1998-08-19
EA199800753A1 (ru) 1999-02-25
CZ260798A3 (cs) 1999-05-12
ES2162196T3 (es) 2001-12-16
KR19990087091A (ko) 1999-12-15
YU6797A (sh) 1999-09-27
CA2246721A1 (en) 1997-08-28
AR005969A1 (es) 1999-07-21
NZ331461A (en) 1999-05-28
EP0791591B1 (en) 2001-08-29
DK0791591T3 (da) 2001-10-08
CO4761064A1 (es) 1999-04-27

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