NO981146L - Transcytotiske midler og forsterkere for medikamentleveranser - Google Patents

Transcytotiske midler og forsterkere for medikamentleveranser

Info

Publication number
NO981146L
NO981146L NO981146A NO981146A NO981146L NO 981146 L NO981146 L NO 981146L NO 981146 A NO981146 A NO 981146A NO 981146 A NO981146 A NO 981146A NO 981146 L NO981146 L NO 981146L
Authority
NO
Norway
Prior art keywords
transcytotic
enhancers
agents
drug delivery
drug
Prior art date
Application number
NO981146A
Other languages
English (en)
Norwegian (no)
Other versions
NO981146D0 (no
Inventor
Andrew Derek Sutton
Asrar Bari Malik
Chinnaswamy Tiruppathi
Richard Alan Johnson
Original Assignee
Andaris Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9606315.1A external-priority patent/GB9606315D0/en
Application filed by Andaris Ltd filed Critical Andaris Ltd
Publication of NO981146D0 publication Critical patent/NO981146D0/no
Publication of NO981146L publication Critical patent/NO981146L/no

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A61K47/64Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
    • A61K47/6425Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent the peptide or protein in the drug conjugate being a receptor, e.g. CD4, a cell surface antigen, i.e. not a peptide ligand targeting the antigen, or a cell surface determinant, i.e. a part of the surface of a cell
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/68Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
    • A61K47/6835Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site
    • A61K47/6849Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site the antibody targeting a receptor, a cell surface antigen or a cell surface determinant
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
NO981146A 1995-09-21 1998-03-16 Transcytotiske midler og forsterkere for medikamentleveranser NO981146L (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US409795P 1995-09-21 1995-09-21
GBGB9606315.1A GB9606315D0 (en) 1996-03-26 1996-03-26 Transcytosis vehicles and enhancers for drug delivery
PCT/GB1996/002326 WO1997010850A1 (en) 1995-09-21 1996-09-20 Transcytosis vehicles and enhancers for drug delivery

Publications (2)

Publication Number Publication Date
NO981146D0 NO981146D0 (no) 1998-03-16
NO981146L true NO981146L (no) 1998-03-16

Family

ID=26308989

Family Applications (1)

Application Number Title Priority Date Filing Date
NO981146A NO981146L (no) 1995-09-21 1998-03-16 Transcytotiske midler og forsterkere for medikamentleveranser

Country Status (15)

Country Link
US (1) US6204054B1 (ru)
EP (1) EP0851767A1 (ru)
JP (1) JPH11512451A (ru)
KR (1) KR19990063632A (ru)
CN (1) CN1195995A (ru)
AU (1) AU717329B2 (ru)
BR (1) BR9610492A (ru)
CA (1) CA2230479A1 (ru)
CZ (1) CZ50398A3 (ru)
HU (1) HUP9900017A3 (ru)
NO (1) NO981146L (ru)
NZ (1) NZ318472A (ru)
PL (1) PL326078A1 (ru)
RU (1) RU2169010C2 (ru)
WO (1) WO1997010850A1 (ru)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6391343B1 (en) 1991-01-15 2002-05-21 Hemosphere, Inc. Fibrinogen-coated particles for therapeutic use
US20070117863A1 (en) * 1993-02-22 2007-05-24 Desai Neil P Novel formulations of pharmacological agents, methods for the preparation thereof and methods for the use thereof
US6165976A (en) 1994-06-23 2000-12-26 Astra Aktiebolag Therapeutic preparation for inhalation
DE69530519T2 (de) 1994-12-22 2004-03-04 Astrazeneca Ab Parathyroidhormon pth enthaltende therapeutische zubereitung zur inhalation
US6261787B1 (en) * 1996-06-03 2001-07-17 Case Western Reserve University Bifunctional molecules for delivery of therapeutics
US20070092563A1 (en) * 1996-10-01 2007-04-26 Abraxis Bioscience, Inc. Novel formulations of pharmacological agents, methods for the preparation thereof and methods for the use thereof
AU741528B2 (en) 1997-06-05 2001-12-06 Hemosphere, Inc. Fibrinogen-coated microspheres
US20030199425A1 (en) * 1997-06-27 2003-10-23 Desai Neil P. Compositions and methods for treatment of hyperplasia
GB9801070D0 (en) * 1998-01-19 1998-03-18 Andaris Ltd HIV inhibition
WO2001074400A1 (fr) * 2000-04-03 2001-10-11 Santen Pharmaceutical Co., Ltd. Transporteurs et systeme de distribution de medicament les utilisant
WO2002032396A2 (en) * 2000-10-16 2002-04-25 Massachusetts Institute Of Technology Lipid-protein-sugar particles for delivery of nucleic acids
AU2002210383A1 (en) * 2000-10-16 2002-04-29 Proteopharma Aps The function of a haptoglobin-haemoglobin receptor and the uses thereof
EP1355941A2 (en) * 2001-02-02 2003-10-29 ConjuChem, Inc. Long lasting growth hormone releasing factor derivatives
WO2003000711A1 (en) * 2001-06-22 2003-01-03 The University Of British Columbia Antimitotic eleuthesides
KR20040039428A (ko) * 2001-09-28 2004-05-10 산텐 세이야꾸 가부시키가이샤 약물-폴리에틸렌글리콜 결합체를 함유하는 안조직 내 주입제
US7482366B2 (en) 2001-12-21 2009-01-27 X-Ceptor Therapeutics, Inc. Modulators of LXR
EP1465869B1 (en) * 2001-12-21 2013-05-15 Exelixis Patent Company LLC Modulators of lxr
US20040038303A1 (en) * 2002-04-08 2004-02-26 Unger Gretchen M. Biologic modulations with nanoparticles
LT1585548T (lt) 2002-12-09 2018-09-25 Abraxis Bioscience, Llc Farmakologinių agentų kompozicijos ir įvedimo būdai
RU2361615C2 (ru) * 2002-12-09 2009-07-20 Абраксис Байосайенс, Ллс. Композиции и способы доставки фармакологических агентов
MXPA05006169A (es) * 2002-12-09 2006-03-30 American Biosciences Composiciones y metodos para el suministro de agentes farmacologicos.
EP2239273B1 (en) * 2003-11-13 2013-10-09 Hanmi Science Co., Ltd. A pharmaceutical composition comprosing an immunoglobulin fc as a carrier
AU2006249235B2 (en) 2004-05-14 2010-11-11 Abraxis Bioscience, Llc Sparc and methods of use thereof
US7666991B2 (en) * 2005-12-05 2010-02-23 Trinity Biosystems, Inc. Compositions for needleless delivery of antibodies
EP2253326B1 (en) * 2008-02-28 2018-04-04 Toray Industries, Inc. Pharmaceutical composition for transnasal administration
US20100166808A1 (en) * 2008-11-17 2010-07-01 Giovanni Marco Pauletti Method of Facilitating Intracellular Uptake or Transcellular Transport of Cargo Using Nanocarriers Containing Optimal Surface Densities of Integrin-Specific Ligands
AU2009322145A1 (en) * 2008-12-05 2011-06-23 Abraxis Bioscience, Llc SPARC Binding ScFvs
US9127079B2 (en) 2009-10-16 2015-09-08 The University Of British Columbia Inhibitors of phosphatase and tensin homolog (PTEN) conjugates
JP5818319B2 (ja) 2009-12-14 2015-11-18 国立大学法人北海道大学 脂質膜構造体に細胞透過能を付与および/または脂質膜構造体の細胞透過能を増強するペプチド、ならびにそれらペプチドと結合した脂質を構成脂質として含む、細胞透過能を有するまたは細胞透過能が増強された脂質膜構造体
BR112013006088B1 (pt) * 2010-09-15 2022-06-14 Randall J Mrsny Construto de entrega isolado, e, composição farmacêutica
WO2014197546A1 (en) * 2013-06-04 2014-12-11 The Johns Hopkins University Therapeutic strategy via controllable transepithelial delivery of therapeutics and diagnostics
CA2959660A1 (en) 2014-09-03 2016-03-10 Genesegues, Inc. Therapeutic nanoparticles and related compositions, methods, and systems

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4801575A (en) 1986-07-30 1989-01-31 The Regents Of The University Of California Chimeric peptides for neuropeptide delivery through the blood-brain barrier
US5254342A (en) 1991-09-30 1993-10-19 University Of Southern California Compositions and methods for enhanced transepithelial and transendothelial transport or active agents
WO1993020834A1 (en) * 1992-04-10 1993-10-28 Brigham And Women's Hospital Methods and compositions for oral delivery of therapeutic agents

Also Published As

Publication number Publication date
HUP9900017A3 (en) 2001-08-28
PL326078A1 (en) 1998-08-17
NZ318472A (en) 1999-10-28
HUP9900017A2 (hu) 1999-04-28
MX9802286A (es) 1998-08-30
CN1195995A (zh) 1998-10-14
JPH11512451A (ja) 1999-10-26
EP0851767A1 (en) 1998-07-08
WO1997010850A1 (en) 1997-03-27
NO981146D0 (no) 1998-03-16
KR19990063632A (ko) 1999-07-26
AU717329B2 (en) 2000-03-23
AU6995796A (en) 1997-04-09
BR9610492A (pt) 1999-03-30
US6204054B1 (en) 2001-03-20
CA2230479A1 (en) 1997-03-27
CZ50398A3 (cs) 1998-07-15
RU2169010C2 (ru) 2001-06-20

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