NO980337L - Penicillaminamidderivater - Google Patents

Penicillaminamidderivater

Info

Publication number
NO980337L
NO980337L NO980337A NO980337A NO980337L NO 980337 L NO980337 L NO 980337L NO 980337 A NO980337 A NO 980337A NO 980337 A NO980337 A NO 980337A NO 980337 L NO980337 L NO 980337L
Authority
NO
Norway
Prior art keywords
group
amino
alkyl group
compounds
butanoylüprolylüaminomethylcyclohexane
Prior art date
Application number
NO980337A
Other languages
English (en)
Other versions
NO980337D0 (no
NO311568B1 (no
Inventor
Masahiro Oshima
Norimichi Iwase
Naoto Inakoshi
Koichi Sugawara
Misao Okitsu
Original Assignee
Mitsubishi Chem Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mitsubishi Chem Corp filed Critical Mitsubishi Chem Corp
Publication of NO980337D0 publication Critical patent/NO980337D0/no
Publication of NO980337L publication Critical patent/NO980337L/no
Publication of NO311568B1 publication Critical patent/NO311568B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/0606—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing heteroatoms not provided for by C07K5/06086 - C07K5/06139, e.g. Ser, Met, Cys, Thr
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Genetics & Genomics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Steroid Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Hydrogenated Pyridines (AREA)
NO19980337A 1995-07-26 1998-01-26 Penicillaminamidderivater og medikament inneholdende disse NO311568B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP19065195 1995-07-26
PCT/JP1996/002027 WO1997005108A1 (fr) 1995-07-26 1996-07-19 Derives de penicillinamine amide

Publications (3)

Publication Number Publication Date
NO980337D0 NO980337D0 (no) 1998-01-26
NO980337L true NO980337L (no) 1998-03-17
NO311568B1 NO311568B1 (no) 2001-12-10

Family

ID=16261639

Family Applications (1)

Application Number Title Priority Date Filing Date
NO19980337A NO311568B1 (no) 1995-07-26 1998-01-26 Penicillaminamidderivater og medikament inneholdende disse

Country Status (15)

Country Link
US (1) US6239150B1 (no)
EP (1) EP0846682B9 (no)
JP (1) JP4050316B2 (no)
KR (1) KR100445094B1 (no)
CN (1) CN1121384C (no)
AT (1) ATE226192T1 (no)
AU (1) AU725483B2 (no)
CA (1) CA2227607C (no)
DE (1) DE69624365T2 (no)
EA (1) EA000966B1 (no)
ES (1) ES2185785T3 (no)
HU (1) HUP9802291A3 (no)
NO (1) NO311568B1 (no)
NZ (1) NZ312791A (no)
WO (1) WO1997005108A1 (no)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0918054B1 (en) * 1997-11-19 2002-05-29 Mitsubishi Chemical Corporation A 1/2 sulfate of ((S)-1-((S)-2-((trans-4-aminocyclohexylmethyl) carbamoyl) pyrrolidine-1-carbonyl)-2-iso-propylthio-2-methylpropyl) carbamic acid propyl ester
US6455571B1 (en) * 1998-04-23 2002-09-24 Abbott Laboratories Inhibitors of neuraminidases
US6316488B1 (en) * 1999-06-17 2001-11-13 Merck & Co., Inc. Antibiotic compound
US6713502B2 (en) * 2000-05-05 2004-03-30 Smithkline Beecham Corporation Anti-infectives
DE10049937A1 (de) * 2000-10-06 2002-04-11 Knoll Ag Niedermolekulare Inhibitoren von Serinproteasen mit Polyhydroxyalkyl- und Polyhydroxycycloalkylresten
WO2007049587A1 (ja) * 2005-10-24 2007-05-03 Mitsubishi Tanabe Pharma Corporation 腸溶性製剤
US9176147B2 (en) 2009-10-29 2015-11-03 Wisconsin Alumni Research Foundation Detection of B-cell activating factor as a biomarker for antibody mediated rejection in transplant recipients

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0813834B2 (ja) 1990-08-01 1996-02-14 日東紡績株式会社 トリペプチド誘導体及びそれを有効成分とする蛋白分解酵素阻害剤
GB9017694D0 (en) 1990-08-13 1990-09-26 Sandoz Ltd Improvements in or relating to organic chemistry
ATE171709T1 (de) 1992-02-14 1998-10-15 Corvas Int Inc Inhibitoren der thrombose
TW223629B (no) 1992-03-06 1994-05-11 Hoffmann La Roche
US5371072A (en) 1992-10-16 1994-12-06 Corvas International, Inc. Asp-Pro-Arg α-keto-amide enzyme inhibitors
FR2701951B1 (fr) 1993-02-24 1995-06-09 Adir Nouveaux derives peptidiques de l'acide boronique, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
IL109319A0 (en) 1993-04-27 1994-07-31 Du Pont Merck Pharma Amidino and guanidino substituted boronic acid compounds
AU670381B2 (en) 1993-04-30 1996-07-11 Merck & Co., Inc. Thrombin inhibitors
US5672582A (en) 1993-04-30 1997-09-30 Merck & Co., Inc. Thrombin inhibitors
SE9301916D0 (sv) 1993-06-03 1993-06-03 Ab Astra New peptides derivatives
JP3840668B2 (ja) 1994-01-27 2006-11-01 三菱化学株式会社 プロリンアミド誘導体
AU1025795A (en) 1994-01-27 1995-08-03 Mitsubishi Chemical Corporation Prolineamide derivatives
US5510369A (en) 1994-07-22 1996-04-23 Merck & Co., Inc. Pyrrolidine thrombin inhibitors

Also Published As

Publication number Publication date
EA199800168A1 (ru) 1998-10-29
DE69624365T2 (de) 2003-06-26
CN1197454A (zh) 1998-10-28
AU725483B2 (en) 2000-10-12
KR100445094B1 (ko) 2005-06-17
EA000966B1 (ru) 2000-08-28
EP0846682A4 (en) 1998-09-30
NZ312791A (en) 1999-07-29
CA2227607A1 (en) 1997-02-13
EP0846682B9 (en) 2003-05-14
EP0846682B1 (en) 2002-10-16
HUP9802291A3 (en) 1999-06-28
EP0846682A1 (en) 1998-06-10
CA2227607C (en) 2008-06-10
ATE226192T1 (de) 2002-11-15
WO1997005108A1 (fr) 1997-02-13
DE69624365D1 (de) 2002-11-21
HUP9802291A2 (hu) 1999-01-28
CN1121384C (zh) 2003-09-17
US6239150B1 (en) 2001-05-29
ES2185785T3 (es) 2003-05-01
NO980337D0 (no) 1998-01-26
JP4050316B2 (ja) 2008-02-20
AU6470696A (en) 1997-02-26
KR19990029018A (ko) 1999-04-15
NO311568B1 (no) 2001-12-10

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Legal Events

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