NO975852D0 - Nye vitamin D-derivater med C-25-substituenter, fremgangsmåte for fremstilling av disse, mellomprodukter og deres anvendelse ved fremstilling av medikamenter - Google Patents

Nye vitamin D-derivater med C-25-substituenter, fremgangsmåte for fremstilling av disse, mellomprodukter og deres anvendelse ved fremstilling av medikamenter

Info

Publication number
NO975852D0
NO975852D0 NO975852A NO975852A NO975852D0 NO 975852 D0 NO975852 D0 NO 975852D0 NO 975852 A NO975852 A NO 975852A NO 975852 A NO975852 A NO 975852A NO 975852 D0 NO975852 D0 NO 975852D0
Authority
NO
Norway
Prior art keywords
preparing
medications
intermediates
substituents
derivatives
Prior art date
Application number
NO975852A
Other languages
English (en)
Other versions
NO975852L (no
NO317059B1 (no
Inventor
Gerald Kirsch
Andreas Steinmeyer
Guenter Neef
Katica Schwarz
Ruth Thieroff-Ekerdt
Herbert Wiesinger
Andreas Menrad
Martin Heberey
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Publication of NO975852D0 publication Critical patent/NO975852D0/no
Publication of NO975852L publication Critical patent/NO975852L/no
Publication of NO317059B1 publication Critical patent/NO317059B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/14—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Urology & Nephrology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Rheumatology (AREA)
  • Communicable Diseases (AREA)
  • Nutrition Science (AREA)
  • Oncology (AREA)
  • Immunology (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Virology (AREA)
  • Pain & Pain Management (AREA)
  • Neurosurgery (AREA)
  • Dermatology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Steroid Compounds (AREA)
NO19975852A 1995-06-14 1997-12-12 Nye vitamin D-derivater med C-25-substituenter, fremgangsmate for fremstilling av disse, mellomprodukter og anvendelse av vitamin D-derivatene ved fremstilling av legemidler NO317059B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19522797 1995-06-14
PCT/EP1996/001788 WO1997000242A1 (de) 1995-06-14 1996-04-30 Neue vitamin d-derivate mit substituenten an c-25, verfahren zu ihrer herstellung, zwischenprodukte und die verwendung zur herstellung von arzneimitteln

Publications (3)

Publication Number Publication Date
NO975852D0 true NO975852D0 (no) 1997-12-12
NO975852L NO975852L (no) 1998-02-16
NO317059B1 NO317059B1 (no) 2004-08-02

Family

ID=7765061

Family Applications (1)

Application Number Title Priority Date Filing Date
NO19975852A NO317059B1 (no) 1995-06-14 1997-12-12 Nye vitamin D-derivater med C-25-substituenter, fremgangsmate for fremstilling av disse, mellomprodukter og anvendelse av vitamin D-derivatene ved fremstilling av legemidler

Country Status (19)

Country Link
US (2) US6372731B1 (no)
EP (1) EP0832063B1 (no)
JP (1) JPH11507649A (no)
AT (1) ATE189888T1 (no)
AU (1) AU707942B2 (no)
CA (1) CA2224440A1 (no)
CZ (1) CZ291915B6 (no)
DE (1) DE59604498D1 (no)
DK (1) DK0832063T3 (no)
ES (1) ES2144239T3 (no)
GR (1) GR3033459T3 (no)
HU (1) HUP9801059A3 (no)
IL (1) IL118366A (no)
NO (1) NO317059B1 (no)
NZ (1) NZ307549A (no)
PT (1) PT832063E (no)
TW (1) TW351714B (no)
WO (1) WO1997000242A1 (no)
ZA (1) ZA965098B (no)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5795882A (en) * 1992-06-22 1998-08-18 Bone Care International, Inc. Method of treating prostatic diseases using delayed and/or sustained release vitamin D formulations
DE19619036A1 (de) * 1996-04-30 1997-11-13 Schering Ag Neue Vitamin D-Derivate mit carbo- oder heterocyclischen Substituenten an C-25, Verfahren zu ihrer Herstellung und die Verwendung zur Herstellung von Arzneimitteln
US6392071B1 (en) * 1997-03-17 2002-05-21 Wisconsin Alumni: Research Foundation 26,27-homologated-20-EPI-2-alkylidene-19-nor-vitamin D compounds
AU1022999A (en) * 1997-09-08 1999-03-29 F. Hoffmann-La Roche Ag 1,3-dihydroxy-20,20-dialkyl-vitamin d3 analogs
DE19744127B4 (de) * 1997-10-01 2006-10-05 Schering Ag Neue Vitamin D-Derivate mit Cyclopropylringen in den Seitenketten, Verfahren und Zwischenprodukte zu ihrer Herstellung sowie ihre Verwendung zur Herstellung von Arzneimitteln
US6531459B1 (en) * 1997-12-17 2003-03-11 Schering Aktiengesellschaft Vitamin D derivatives with phosphorus atoms in the side chains
EP0927721A1 (de) * 1997-12-17 1999-07-07 Schering Aktiengesellschaft Neue Vitamin D-Derivate mit Phosphoratomen in den Seitenketten, Zwischenprodukte bei ihrer Herstellung und die Verwendung zur Herstellung von Arzneimitteln
US5972917A (en) * 1998-05-29 1999-10-26 Bone Care Int Inc 1 α-hydroxy-25-ene-vitamin D, analogs and uses thereof
US20040019024A1 (en) * 2000-08-23 2004-01-29 Seiichi Ishizuka Use of vitamin d derivatives as bone resorption inhibitors
US7491711B2 (en) * 2001-09-21 2009-02-17 Roche Palo Alto Llc Methods of treatment using 3-desoxy vitamin D3 analogs
DE10156596A1 (de) * 2001-11-13 2003-05-28 Schering Ag Vitamin D-Derivate mit Acyloxygruppen in der Seitenkette, Verfahren zu ihrer Herstellung und die Verwendung zur Herstellung von Arzneimitteln
US7351869B2 (en) * 2002-11-18 2008-04-01 Teva Pharmaceutical Industries Ltd Crystallization method for purification of calcipotriene
WO2005079464A2 (en) * 2004-02-17 2005-09-01 Wisconsin Alumni Research Foundation Vitamin d receptor antagonists and their use in treating asthma
MX2007006653A (es) * 2005-10-05 2009-02-17 Sicor Inc Separacion de isomeros de fulvestrant.
BRPI0715636A2 (pt) * 2006-08-29 2013-07-02 Teva Pharma composiÇÕes farmacologicamente ativas estÁveis incluindo compostos contendo vitamina d e corticosteràide com compatibilidade para ph baixo
WO2009108388A2 (en) * 2008-02-28 2009-09-03 University Of Tennessee Research Foundation Enzymatic production or chemical synthesis and uses for 5,7-dienes and uvb conversion products thereof
JPWO2010053165A1 (ja) 2008-11-04 2012-04-05 帝人ファーマ株式会社 ビタミンｄ３ラクタム誘導体
EP2393494A1 (en) * 2009-01-27 2011-12-14 Berg Biosystems, LLC Vitamin d3 and analogs thereof for alleviating side effects associated with chemotherapy
CA2770683C (en) 2009-08-14 2018-09-04 Berg Biosystems, Llc Vitamin d3 and analogs thereof for treating alopecia
EP2714656B1 (en) * 2011-06-03 2017-05-03 Wisconsin Alumni Research Foundation (22e)-2-methylene-26,27-cyclo-22-dehydro-1alpha-hydroxy-19-norvitamin d3 derivatives
WO2013003307A1 (en) * 2011-06-28 2013-01-03 Wisconsin Alumni Research Foundation 2-methylene-(22e)-25-hexanoyl-24-oxo-26,27-cyclo-22-dehydro-19-nor-vitamin d analogs
SG10201709894RA (en) 2013-05-29 2018-01-30 Berg Llc Preventing or mitigating chemotherapy induced alopecia using vitamin d
WO2022078877A1 (en) * 2020-10-12 2022-04-21 Universite De Strasbourg A calcium normalizer targeting the vitamin d receptor and therapeutic uses thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5182396A (en) * 1991-03-29 1993-01-26 Nisshin Flour Milling Co., Ltd. 1-hydroxyvitamin d derivatives
IL107185A (en) * 1992-10-06 1998-02-22 Schering Ag History of 52-carboxylic acid, processes for their preparation and pharmaceutical preparations containing them

Also Published As

Publication number Publication date
EP0832063B1 (de) 2000-02-23
DK0832063T3 (da) 2000-06-13
GR3033459T3 (en) 2000-09-29
ZA965098B (en) 1997-01-22
AU5693096A (en) 1997-01-15
HUP9801059A2 (hu) 1998-08-28
CA2224440A1 (en) 1997-01-03
NO975852L (no) 1998-02-16
US6376480B1 (en) 2002-04-23
HUP9801059A3 (en) 1999-05-28
IL118366A0 (en) 1996-09-12
JPH11507649A (ja) 1999-07-06
AU707942B2 (en) 1999-07-22
WO1997000242A1 (de) 1997-01-03
IL118366A (en) 2004-12-15
ATE189888T1 (de) 2000-03-15
CZ291915B6 (cs) 2003-06-18
ES2144239T3 (es) 2000-06-01
DE59604498D1 (de) 2000-03-30
EP0832063A1 (de) 1998-04-01
NO317059B1 (no) 2004-08-02
US6372731B1 (en) 2002-04-16
TW351714B (en) 1999-02-01
PT832063E (pt) 2000-06-30
CZ403197A3 (cs) 1998-07-15
NZ307549A (en) 1999-11-29

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