NO963987L - Hypokolesterolemiske-, antiatherosklerotiske-, og hypotriglyceridemiske aminoacetylmercaptoderivater - Google Patents
Hypokolesterolemiske-, antiatherosklerotiske-, og hypotriglyceridemiske aminoacetylmercaptoderivaterInfo
- Publication number
- NO963987L NO963987L NO963987A NO963987A NO963987L NO 963987 L NO963987 L NO 963987L NO 963987 A NO963987 A NO 963987A NO 963987 A NO963987 A NO 963987A NO 963987 L NO963987 L NO 963987L
- Authority
- NO
- Norway
- Prior art keywords
- aminoacetylmercapto
- derivatives
- hypotriglyceridemic
- antiatherosclerotic
- hypocholesterolemic
- Prior art date
Links
- -1 aminoacetylmercapto Chemical class 0.000 title abstract 2
- 230000000879 anti-atherosclerotic effect Effects 0.000 title 1
- 230000000871 hypocholesterolemic effect Effects 0.000 title 1
- 230000000999 hypotriglyceridemic effect Effects 0.000 title 1
- 206010003210 Arteriosclerosis Diseases 0.000 abstract 1
- 208000035150 Hypercholesterolemia Diseases 0.000 abstract 1
- 208000011775 arteriosclerosis disease Diseases 0.000 abstract 1
- 208000006575 hypertriglyceridemia Diseases 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06139—Dipeptides with the first amino acid being heterocyclic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/05—Dipeptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Abstract
Foreliggende oppfinnelse angår anvendelse av visse aminoacetyl- mercaptoderivater ved behandling av pasienter som lider av hypertrigly- ceridemi, arteriosklerose og hyperkolesterolemi.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US21735094A | 1994-03-24 | 1994-03-24 | |
PCT/US1995/002458 WO1995025532A1 (en) | 1994-03-24 | 1995-02-28 | Hypocholesterolemic, antiatherosclerotic and hypotriglyceridemic aminoacetylmercapto derivatives |
Publications (2)
Publication Number | Publication Date |
---|---|
NO963987D0 NO963987D0 (no) | 1996-09-23 |
NO963987L true NO963987L (no) | 1996-11-22 |
Family
ID=22810704
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO963987A NO963987L (no) | 1994-03-24 | 1996-09-23 | Hypokolesterolemiske-, antiatherosklerotiske-, og hypotriglyceridemiske aminoacetylmercaptoderivater |
Country Status (19)
Country | Link |
---|---|
US (2) | US5624921A (no) |
EP (1) | EP0751783B1 (no) |
JP (1) | JPH09510476A (no) |
CN (1) | CN1144487A (no) |
AT (1) | ATE189392T1 (no) |
AU (1) | AU698320B2 (no) |
CA (1) | CA2184696C (no) |
DE (1) | DE69514912T2 (no) |
DK (1) | DK0751783T3 (no) |
ES (1) | ES2141923T3 (no) |
FI (1) | FI963783A (no) |
GR (1) | GR3033117T3 (no) |
HU (1) | HUT75160A (no) |
IL (1) | IL113076A (no) |
NO (1) | NO963987L (no) |
NZ (1) | NZ282568A (no) |
PT (1) | PT751783E (no) |
WO (1) | WO1995025532A1 (no) |
ZA (1) | ZA952284B (no) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE10229180A1 (de) * | 2002-06-28 | 2004-01-29 | Aventis Pharma Deutschland Gmbh | Verwendung von Vasopeptidase-Inhibitoren bei der Behandlung von metabolischen Erkrankungen, Nephropathie und mit AGE assoziierten Erkrankungen |
SI1670768T1 (sl) * | 2003-10-08 | 2010-01-29 | Lilly Co Eli | Spojine in metode za zdravljenje dislipidemije |
Family Cites Families (31)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3334095A (en) * | 1965-02-16 | 1967-08-01 | Sandoz Ag | Novel pyrrolo-oxazines and pyrrolo-oxazoles |
US3334091A (en) * | 1965-03-25 | 1967-08-01 | Sandoz Ag | Sedatives |
GB1525845A (en) * | 1976-07-30 | 1978-09-20 | Ucb Sa | 1,2,4,5-tetrahydro-3h-2-benzazepin-3-ones |
IE50839B1 (en) * | 1980-02-26 | 1986-07-23 | Wyeth John & Brother Ltd | Novel processes for preparing proline derivatives and analogous compounds |
EP0042100A1 (de) * | 1980-06-13 | 1981-12-23 | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft | Pyrazolopyridazin-Derivate, Zwischenprodukte und Verfahren zu deren Herstellung, sowie diese enthaltende Arzneimittel |
US4320057A (en) * | 1980-06-23 | 1982-03-16 | American Home Products Corporation | Aryl--pyrrolo--thiazepin--diones and aryl--piperidino--thiazepin--diones |
US4415496A (en) * | 1981-03-23 | 1983-11-15 | Merck & Co., Inc. | Bicyclic lactams |
GB2128984B (en) * | 1982-05-12 | 1985-05-22 | Hoffmann La Roche | Diaza-bicyclic compounds |
ZA833214B (en) * | 1982-05-12 | 1983-12-28 | Hoffmann La Roche | Bicyclic compounds |
US4552889A (en) * | 1983-06-09 | 1985-11-12 | Eli Lilly And Company | 3-Mercaptomethyl-2-oxo-1-pyrrolidine acetic acids and use for hypertension |
US4692438A (en) * | 1984-08-24 | 1987-09-08 | Hoffmann-La Roche Inc. | Pyridazo-diazepines, diazocines, and -triazepines having anti-hypertensive activity |
US4584294A (en) * | 1984-11-07 | 1986-04-22 | Merck & Co., Inc. | Fused tricyclic lactams as angiotensin converting enzyme inhibitors and as antihypertensive agents |
IL78634A0 (en) * | 1985-04-30 | 1986-08-31 | Lilly Co Eli | 7-substituted bicyclic pyrazolidinones |
ZA874106B (en) * | 1986-06-13 | 1987-12-08 | Merrell Dow Pharmaceuticals Inc. | Novel antihypertensive agent |
ZA874107B (no) * | 1986-06-13 | 1987-12-09 | ||
US4973585A (en) * | 1986-06-13 | 1990-11-27 | Merrell Dow Pharmaceuticals | Tricyclic lactams active as antihypertensive agents |
GB8629875D0 (en) * | 1986-12-15 | 1987-01-28 | Hoffmann La Roche | Pyridazodiazepine derivatives |
US4824832A (en) * | 1987-12-30 | 1989-04-25 | Merrell Dow Pharmaceuticals Inc. | Sulfhydryl containing tricyclic lactams and their pharmacological methods of use |
US5061694A (en) * | 1989-10-23 | 1991-10-29 | E. R. Squibb & Sons, Inc. | Method for stabilizing or causing regression of atherosclerosis in coronary arteries employing an ace inhibitor |
GB8926512D0 (en) * | 1989-11-23 | 1990-01-10 | Pfizer Ltd | Therapeutic agents |
US5407960A (en) * | 1989-12-22 | 1995-04-18 | Schering Corporation | Mercaptocycloacyl aminoacid endopeptidase inhibitors |
FR2659332B1 (fr) * | 1990-03-08 | 1994-04-29 | Adit Et Cie | Nouvelles pyrrolo [1,2-a] thieno [3,2-f] diazepines [1,4], leur procede de preparation et les compositions pharmaceutiques qui les contiennent. |
CA2053340C (en) * | 1990-10-18 | 2002-04-02 | Timothy P. Burkholder | Mercaptoacetylamide derivatives useful as inhibitors of enkephalinase and ace |
AU642321B2 (en) * | 1990-12-21 | 1993-10-14 | Merrell Pharmaceuticals Inc. | Novel amino and nitro containing tricyclic compounds useful as inhibitors of ace |
US5208230A (en) * | 1990-12-21 | 1993-05-04 | Merrell Dow Pharmaceuticals | Amino and nitro containing tricyclic compounds useful as inhibitors of ACE |
FR2679564A1 (fr) * | 1991-07-23 | 1993-01-29 | Inst Nat Sante Rech Med | Nouveaux acylmercaptoalcanoldipeptides, leur preparation et les compositions qui les contiennent. |
EP0605589A1 (en) * | 1991-09-16 | 1994-07-13 | Schering Corporation | Pharmaceutical compositions comprising natriuretic peptides or neutral endopeptidase inhibitors for treating or preventing myointimal proliferation |
AU668707B2 (en) * | 1992-02-14 | 1996-05-16 | Merrell Pharmaceuticals Inc. | Aminoacetylmercaptoacetylamide derivatives useful as inhibitors of enkephalinase and ACE |
KR100281450B1 (ko) * | 1992-05-15 | 2001-02-01 | 슈테펜 엘. 네스비트 | 엔케팔리나제 및 안지오텐신 전환 효소의 억제제로서 유용한 신규 메르캅토아세틸아미도 피리다조[1,2]피리다진, 피라졸로[1,2]피리다진, 피리다조[1,2-a][1,2]디아제핀 및 피라졸로[1,2-a][1,2]디아제핀 유도체 |
RU2124503C1 (ru) * | 1992-05-18 | 1999-01-10 | И.Р.Сквибб энд Санз, Инк. | Гетероциклические азотсодержащие производные карбоновой кислоты, способ их получения и фармацевтическая композиция |
US5238932A (en) * | 1992-05-20 | 1993-08-24 | Merrell Dow Pharmaceuticals Inc. | Mercaptoacetylamide tricyclic derivatives useful as inhibitors of enkephalinase |
-
1995
- 1995-02-28 WO PCT/US1995/002458 patent/WO1995025532A1/en active IP Right Grant
- 1995-02-28 AU AU19724/95A patent/AU698320B2/en not_active Ceased
- 1995-02-28 ES ES95912634T patent/ES2141923T3/es not_active Expired - Lifetime
- 1995-02-28 DE DE69514912T patent/DE69514912T2/de not_active Expired - Fee Related
- 1995-02-28 NZ NZ282568A patent/NZ282568A/en unknown
- 1995-02-28 DK DK95912634T patent/DK0751783T3/da active
- 1995-02-28 EP EP95912634A patent/EP0751783B1/en not_active Expired - Lifetime
- 1995-02-28 PT PT95912634T patent/PT751783E/pt unknown
- 1995-02-28 JP JP7524646A patent/JPH09510476A/ja not_active Abandoned
- 1995-02-28 HU HU9602604A patent/HUT75160A/hu unknown
- 1995-02-28 CN CN95192233A patent/CN1144487A/zh active Pending
- 1995-02-28 AT AT95912634T patent/ATE189392T1/de not_active IP Right Cessation
- 1995-02-28 CA CA002184696A patent/CA2184696C/en not_active Expired - Fee Related
- 1995-03-20 ZA ZA952284A patent/ZA952284B/xx unknown
- 1995-03-22 IL IL11307695A patent/IL113076A/xx not_active IP Right Cessation
- 1995-08-09 US US08/513,101 patent/US5624921A/en not_active Expired - Fee Related
- 1995-10-26 US US08/548,604 patent/US5602122A/en not_active Expired - Fee Related
-
1996
- 1996-09-23 NO NO963987A patent/NO963987L/no not_active Application Discontinuation
- 1996-09-23 FI FI963783A patent/FI963783A/fi unknown
-
2000
- 2000-03-31 GR GR20000400807T patent/GR3033117T3/el not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
ES2141923T3 (es) | 2000-04-01 |
EP0751783B1 (en) | 2000-02-02 |
WO1995025532A1 (en) | 1995-09-28 |
DE69514912T2 (de) | 2000-10-05 |
CA2184696C (en) | 2001-01-02 |
ATE189392T1 (de) | 2000-02-15 |
AU698320B2 (en) | 1998-10-29 |
EP0751783A1 (en) | 1997-01-08 |
CA2184696A1 (en) | 1995-09-28 |
FI963783A0 (fi) | 1996-09-23 |
PT751783E (pt) | 2000-05-31 |
ZA952284B (en) | 1996-01-09 |
AU1972495A (en) | 1995-10-09 |
NZ282568A (en) | 1997-07-27 |
US5624921A (en) | 1997-04-29 |
JPH09510476A (ja) | 1997-10-21 |
US5602122A (en) | 1997-02-11 |
HUT75160A (en) | 1997-04-28 |
IL113076A0 (en) | 1995-06-29 |
CN1144487A (zh) | 1997-03-05 |
NO963987D0 (no) | 1996-09-23 |
DE69514912D1 (de) | 2000-03-09 |
IL113076A (en) | 2000-09-28 |
GR3033117T3 (en) | 2000-08-31 |
FI963783A (fi) | 1996-09-23 |
DK0751783T3 (da) | 2000-06-26 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
PL323825A1 (en) | Peptidyloheterocycli compounds useful in treating diorders associated with thrombosin | |
MY180762A (en) | Combination therapy comprising glucose reabsorption inhibitors and ppar modulators. | |
EP0909561A3 (en) | Use of reboxetine for the treatment of attention-deficit/hyperactivity disorder | |
IT1305069B1 (it) | Polsino per la prevenzione e il trattamento della sindrome del tunnelcarpale e metodo per la sua applicazione | |
DE69620691T2 (de) | Therapeutisches Mittel zur Behandlung der Hypercholesterinämie | |
NO963987L (no) | Hypokolesterolemiske-, antiatherosklerotiske-, og hypotriglyceridemiske aminoacetylmercaptoderivater | |
DK0751775T3 (da) | Hypocholesterolæmiske, antiatherosclerotiske og hypotriglyceridæmiske mercaptoacetylamidderivater | |
PT869785E (pt) | 4-hidroxicumarina-3-carboxamidas para o tratamento de diabetes mellitus nao insulinodependente | |
NO963988L (no) | Hypokolesterolemiske-, antiatherosklerotiske-, og hypotriglyceridemiske mercaptoacetylamidderivater | |
IS5231A (is) | Vefjaþáttur sem hefur áhrif á blóðæðarmyndun | |
ZA977004B (en) | Therapeutic product and its use | |
UA30556A (uk) | Спосіб модуляції гоєння ран | |
UA31270A (uk) | Спосіб формування товстокишкового анастомозу |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FC2A | Withdrawal, rejection or dismissal of laid open patent application |